| scholarly article | Q13442814 |
| P6179 | Dimensions Publication ID | 1036438887 |
| P356 | DOI | 10.1038/NATURE07966 |
| P3181 | OpenCitations bibliographic resource ID | 839315 |
| P698 | PubMed publication ID | 19536266 |
| P50 | author | Ilme Schlichting | Q1658972 |
| P2093 | author name string | Dmitri A Ryjenkov | |
| Elisabeth Hartmann | |||
| Jochen Reinstein | |||
| Julia J Griese | |||
| Mark Gomelsky | |||
| Natalia V Kirienko | |||
| Robert L Shoeman | |||
| Thomas R M Barends | |||
| Thorsten Beitlich | |||
| P2860 | cites work | The ubiquitous protein domain EAL is a cyclic diguanylate-specific phosphodiesterase: enzymatically active and inactive EAL domains | Q24532048 |
| The structural basis of cyclic diguanylate signal transduction by PilZ domains | Q24678233 | ||
| Pfam: clans, web tools and services | Q25257103 | ||
| Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination | Q26778405 | ||
| Structure and insight into blue light-induced changes in the BlrP1 BLUF domain | Q27653640 | ||
| Crystal Structures of YkuI and Its Complex with Second Messenger Cyclic Di-GMP Suggest Catalytic Mechanism of Phosphodiester Bond Cleavage by EAL Domains | Q27653952 | ||
| SOLVE and RESOLVE: automated structure solution, density modification and model building | Q27860452 | ||
| SOLVE and RESOLVE: automated structure solution and density modification | Q27860481 | ||
| Coot: model-building tools for molecular graphics | Q27860505 | ||
| Automated structure solution with autoSHARP | Q27860516 | ||
| Version 1.2 of the Crystallography and NMR system | Q27860583 | ||
| Refinement of macromolecular structures by the maximum-likelihood method | Q27861011 | ||
| XtalView/Xfit--A versatile program for manipulating atomic coordinates and electron density | Q27861034 | ||
| Analysis of Pseudomonas aeruginosa diguanylate cyclases and phosphodiesterases reveals a role for bis-(3'-5')-cyclic-GMP in virulence | Q28492942 | ||
| Aminoglycoside antibiotics induce bacterial biofilm formation | Q28493241 | ||
| Automatic processing of rotation diffraction data from crystals of initially unknown symmetry and cell constants | Q29546524 | ||
| Automated structure solution, density modification and model building | Q29620768 | ||
| Structure of a bacterial BLUF photoreceptor: insights into blue light-mediated signal transduction | Q33933797 | ||
| BLUF: a novel FAD-binding domain involved in sensory transduction in microorganisms | Q34153242 | ||
| Hydrogen-bond switching through a radical pair mechanism in a flavin-binding photoreceptor | Q34984165 | ||
| Crystal structures of the Synechocystis photoreceptor Slr1694 reveal distinct structural states related to signaling | Q36839565 | ||
| Structure of a novel photoreceptor, the BLUF domain of AppA from Rhodobacter sphaeroides | Q37415159 | ||
| Catalytic mechanism of cyclic di-GMP-specific phosphodiesterase: a study of the EAL domain-containing RocR from Pseudomonas aeruginosa | Q38608396 | ||
| AppA, a redox regulator of photosystem formation in Rhodobacter sphaeroides 2.4.1, is a flavoprotein. Identification of a novel fad binding domain. | Q42688340 | ||
| Molecular models predict light-induced glutamine tautomerization in BLUF photoreceptors | Q43205756 | ||
| Structural requirements for key residues and auxiliary portions of a BLUF domain | Q44184864 | ||
| Enzymes do what is expected (chalcone isomerase versus chorismate mutase). | Q44303357 | ||
| A conclusive mechanism of the photoinduced reaction cascade in blue light using flavin photoreceptors | Q46414721 | ||
| Structure of a cyanobacterial BLUF protein, Tll0078, containing a novel FAD-binding blue light sensor domain | Q46474274 | ||
| A glutamate-alanine-leucine (EAL) domain protein of Salmonella controls bacterial survival in mice, antioxidant defence and killing of macrophages: role of cyclic diGMP. | Q46480554 | ||
| First computational evidence for a catalytic bridging hydroxide ion in a phosphodiesterase active site | Q49312895 | ||
| Crystal structures of the AppA BLUF domain photoreceptor provide insights into blue light-mediated signal transduction | Q50476145 | ||
| The flagellar sigma factor FliA regulates adhesion and invasion of Crohn disease-associated Escherichia coli via a cyclic dimeric GMP-dependent pathway. | Q54434727 | ||
| The cyclic diguanylic acid regulatory system of cellulose synthesis in Acetobacter xylinum. Chemical synthesis and biological activity of cyclic nucleotide dimer, trimer, and phosphothioate derivatives | Q68483799 | ||
| Catalysis of the hydrolysis of phosphorylated pyridines by Mg(OH)+: a possible model for enzymatic phosphoryl transfer | Q68872016 | ||
| Determination of the sedimentation coefficient distribution by least-squares boundary modeling | Q74145637 | ||
| The mechanism of cyclic nucleotide hydrolysis in the phosphodiesterase catalytic site | Q80138651 | ||
| P433 | issue | 7249 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 1015-8 | |
| P577 | publication date | 2009-06-18 | |
| P1433 | published in | Nature | Q180445 |
| P1476 | title | Structure and mechanism of a bacterial light-regulated cyclic nucleotide phosphodiesterase | |
| P478 | volume | 459 |
| Q91654874 | A Conserved Regulatory Circuit Controls Large Adhesins in Vibrio cholerae |
| Q89582639 | A Cyclic-di-GMP signalling network regulates biofilm formation and surface associated motility of Acinetobacter baumannii 17978 |
| Q46310941 | A LOV-domain-mediated blue-light-activated adenylate (adenylyl) cyclase from the cyanobacterium Microcoleus chthonoplastes PCC 7420. |
| Q35080173 | A Q63E Rhodobacter sphaeroides AppA BLUF domain mutant is locked in a pseudo-light-excited signaling state |
| Q88573763 | A bipartite periplasmic receptor-diguanylate cyclase pair (XAC2383-XAC2382) in the bacterium Xanthomonas citri |
| Q48341315 | A near-infrared light responsive c-di-GMP module-based AND logic gate in Shewanella oneidensis |
| Q30381513 | A proposal for a dipole-generated BLUF domain mechanism |
| Q27678464 | A ternary AppA–PpsR–DNA complex mediates light regulation of photosynthesis-related gene expression |
| Q51602292 | Analysis of proton wires in the enzyme active site suggests a mechanism of c-di-GMP hydrolysis by the EAL domain phosphodiesterases. |
| Q50196724 | Anomalous pressure effects on the photoreaction of a light-sensor protein from Synechocystis, PixD (Slr1694), and the compressibility change of its intermediates |
| Q40589121 | Application of Synthetic Peptide Arrays To Uncover Cyclic Di-GMP Binding Motifs |
| Q27003155 | Applications of hydrogen deuterium exchange (HDX) for the characterization of conformational dynamics in light-activated photoreceptors |
| Q47417457 | BLUF hydrogen network dynamics and UV/Vis spectra: a combined molecular dynamics and quantum chemical study. |
| Q28085674 | Bacterial Signal Transduction by Cyclic Di-GMP and Other Nucleotide Second Messengers |
| Q39628830 | Binding of cyclic diguanylate in the non-catalytic EAL domain of FimX induces a long-range conformational change. |
| Q37800205 | Biophysical assays for protein interactions in the Wsp sensory system and biofilm formation. |
| Q57850688 | Blue-Light Receptors for Optogenetics |
| Q28533508 | C-di-GMP hydrolysis by Pseudomonas aeruginosa HD-GYP phosphodiesterases: analysis of the reaction mechanism and novel roles for pGpG |
| Q42606708 | Catalytically incompetent by design |
| Q91891762 | CdbA is a DNA-binding protein and c-di-GMP receptor important for nucleoid organization and segregation in Myxococcus xanthus |
| Q38799745 | Characterization of elements involved in allosteric light regulation of phosphodiesterase activity by comparison of different functional BlrP1 states |
| Q30396694 | Coincidence detection and bi-directional transmembrane signaling control a bacterial second messenger receptor. |
| Q34331215 | Comparative analysis of diguanylate cyclase and phosphodiesterase genes in Klebsiella pneumoniae. |
| Q34099199 | Complex c-di-GMP signaling networks mediate transition between virulence properties and biofilm formation in Salmonella enterica serovar Typhimurium |
| Q47163053 | Computational and NMR spectroscopy insights into the conformation of cyclic di-nucleotides |
| Q50439681 | Computational characterization of reaction intermediates in the photocycle of the sensory domain of the AppA blue light photoreceptor. |
| Q30402180 | Correlated single-crystal electronic absorption spectroscopy and X-ray crystallography at NSLS beamline X26-C. |
| Q50441547 | Coupling between the BLUF and EAL domains in the blue light-regulated phosphodiesterase BlrP1. |
| Q27675706 | Crystal Structure of an EAL Domain in Complex with Reaction Product 5′-pGpG |
| Q28248973 | Crystal structure of a c-di-AMP riboswitch reveals an internally pseudo-dimeric RNA |
| Q27680495 | Crystal structure of an HD-GYP domain cyclic-di-GMP phosphodiesterase reveals an enzyme with a novel trinuclear catalytic iron centre |
| Q42545699 | Cyanobacteriochrome SesA is a diguanylate cyclase that induces cell aggregation in Thermosynechococcus. |
| Q35701612 | Cyclic Di-GMP Signaling Contributes to Pseudomonas aeruginosa-Mediated Catheter-Associated Urinary Tract Infection |
| Q28504076 | Cyclic Di-GMP phosphodiesterases RmdA and RmdB are involved in regulating colony morphology and development in Streptomyces coelicolor |
| Q26799100 | Cyclic Dinucleotide-Controlled Regulatory Pathways in Streptomyces Species |
| Q38118107 | Cyclic di-AMP: another second messenger enters the fray |
| Q24338485 | Cyclic di-GMP sensing via the innate immune signaling protein STING |
| Q36396858 | Cyclic di-GMP stimulates biofilm formation and inhibits virulence of Francisella novicida |
| Q37951094 | Cyclic di-GMP, an established secondary messenger still speeding up. |
| Q28541732 | Cyclic di-GMP-dependent signaling pathways in the pathogenic Firmicute Listeria monocytogenes |
| Q39120722 | Cyclic di-GMP: second messenger extraordinaire |
| Q26850396 | Cyclic di-GMP: the first 25 years of a universal bacterial second messenger |
| Q34501565 | Cyclic diguanylate signaling proteins control intracellular growth of Legionella pneumophila |
| Q37220147 | De- and repolarization mechanism of flagellar morphogenesis during a bacterial cell cycle. |
| Q34545333 | Detection of cyclic diguanylate G-octaplex assembly and interaction with proteins |
| Q40337429 | Dimerisation induced formation of the active site and the identification of three metal sites in EAL-phosphodiesterases |
| Q40058765 | Discovery of the Second Messenger Cyclic di-GMP. |
| Q36390608 | Diversity of Cyclic Di-GMP-Binding Proteins and Mechanisms |
| Q33540454 | Diversity of structure and function of response regulator output domains |
| Q64063942 | DncV Synthesizes Cyclic GMP-AMP and Regulates Biofilm Formation and Motility in ECOR31 |
| Q38805397 | Evidence for Tautomerisation of Glutamine in BLUF Blue Light Receptors by Vibrational Spectroscopy and Computational Chemistry |
| Q27322162 | Expression and Genetic Activation of Cyclic Di-GMP-Specific Phosphodiesterases in Escherichia coli |
| Q43019989 | Finally! The structural secrets of a HD-GYP phosphodiesterase revealed |
| Q27696249 | Formation and dimerization of the phosphodiesterase active site of the Pseudomonas aeruginosa MorA, a bi-functional c-di-GMP regulator |
| Q27007001 | From Plant Infectivity to Growth Patterns: The Role of Blue-Light Sensing in the Prokaryotic World |
| Q37253126 | Functional characterization of core components of the Bacillus subtilis cyclic-di-GMP signaling pathway |
| Q33976662 | GIL, a new c-di-GMP-binding protein domain involved in regulation of cellulose synthesis in enterobacteria. |
| Q64090155 | Genetic dissection of Escherichia coli's master diguanylate cyclase DgcE: Role of the N-terminal MASE1 domain and direct signal input from a GTPase partner system |
| Q36390632 | Genome-Based Comparison of Cyclic Di-GMP Signaling in Pathogenic and Commensal Escherichia coli Strains |
| Q38082430 | Guiding lights: recent developments in optogenetic control of biochemical signals |
| Q36598846 | Identification of c-di-GMP derivatives resistant to an EAL domain phosphodiesterase |
| Q59357088 | Illuminating pathogen-host intimacy through optogenetics |
| Q27681424 | Inherent Regulation of EAL Domain-catalyzed Hydrolysis of Second Messenger Cyclic di-GMP |
| Q47375995 | Insights into biofilm dispersal regulation from the crystal structure of the PAS-GGDEF-EAL region of RbdA from Pseudomonas aeruginosa. |
| Q50278366 | Introduction to the Symposium-in Print: Blue light effects |
| Q26800227 | Investigating neuronal function with optically controllable proteins |
| Q50439064 | Light-generated paramagnetic intermediates in BLUF domains |
| Q50246577 | Light-induced alteration of c-di-GMP level controls motility of Synechocystis sp. PCC 6803. |
| Q37845235 | Lights on and action! Controlling microbial gene expression by light |
| Q41276478 | Membrane-anchored MucR mediates nitrate-dependent regulation of alginate production in Pseudomonas aeruginosa. |
| Q47871055 | Molecular determinant modulates thermal recovery kinetics and structural integrity of the bacterial BLUF photoreceptor |
| Q26853118 | Molecular eyes: proteins that transform light into biological information |
| Q42065060 | Molecular function and potential evolution of the biofilm-modulating blue light-signalling pathway of Escherichia coli. |
| Q41433478 | Molecular mechanism of photoactivation of a light-regulated adenylate cyclase. |
| Q27670482 | Mutational and Structural Studies of the PixD BLUF Output Signal That Affects Light-Regulated Interactions with PixE |
| Q38769055 | Natural Resources for Optogenetic Tools. |
| Q41889063 | Nitric oxide modulates bacterial biofilm formation through a multicomponent cyclic-di-GMP signaling network |
| Q36586267 | Nuclease-Resistant c-di-AMP Derivatives That Differentially Recognize RNA and Protein Receptors |
| Q92245300 | Nucleotide signaling pathway convergence in a cAMP-sensing bacterial c-di-GMP phosphodiesterase |
| Q38047778 | Nucleotide, c-di-GMP, c-di-AMP, cGMP, cAMP, (p)ppGpp signaling in bacteria and implications in pathogenesis. |
| Q34166937 | Old chromophores, new photoactivation paradigms, trendy applications: flavins in blue light-sensing photoreceptors |
| Q50182820 | Optogenetic Module for Dichromatic Control of c-di-GMP Signaling. |
| Q38250355 | Photochemistry of flavoprotein light sensors |
| Q50439066 | Photoreaction in BLUF receptors: proton-coupled electron transfer in the flavin-Gln-Tyr system |
| Q33922838 | Photoreactions of aureochrome-1. |
| Q30538906 | Probing the activity of diguanylate cyclases and c-di-GMP phosphodiesterases in real-time by CD spectroscopy |
| Q39061511 | Progress in Understanding the Molecular Basis Underlying Functional Diversification of Cyclic Dinucleotide Turnover Proteins |
| Q37531714 | Quenching Dynamics of Ultraviolet-Light Perception by UVR8 Photoreceptor |
| Q41906114 | Rationalizing the evolution of EAL domain-based cyclic di-GMP-specific phosphodiesterases |
| Q27679815 | Redox and Light Control the Heme-Sensing Activity of AppA |
| Q38323197 | Redox modulation of flavin and tyrosine determines photoinduced proton-coupled electron transfer and photoactivation of BLUF photoreceptors. |
| Q58769303 | Regulating exopolysaccharide gene wcaF allows control of Escherichia coli biofilm formation |
| Q42914730 | Revealing the functional states in the active site of BLUF photoreceptors from electrochromic shift calculations. |
| Q37748363 | Riboswitch function: flipping the switch or tuning the dimmer? |
| Q37074141 | Second messenger regulation of biofilm formation: breakthroughs in understanding c-di-GMP effector systems |
| Q39310596 | Seeing the light with BLUF proteins. |
| Q36483723 | Self-produced exopolysaccharide is a signal that stimulates biofilm formation in Pseudomonas aeruginosa. |
| Q38010664 | Sensing the messenger: the diverse ways that bacteria signal through c-di-GMP. |
| Q33806123 | Stability and dynamics of cyclic diguanylic acid in solution |
| Q41357740 | Stand-Alone EAL Domain Proteins Form a Distinct Subclass of EAL Proteins Involved in Regulation of Cell Motility and Biofilm Formation in Enterobacteria. |
| Q27666910 | Structural Basis for c-di-GMP-Mediated Inside-Out Signaling Controlling Periplasmic Proteolysis |
| Q27663896 | Structural Insight into the Mechanism of c-di-GMP Hydrolysis by EAL Domain Phosphodiesterases |
| Q35003079 | Structural and mechanistic determinants of c-di-GMP signalling |
| Q61800419 | Structural basis of DSF recognition by its receptor RpfR and its regulatory interaction with the DSF synthase RpfF |
| Q24602499 | Structural basis of ligand binding by a c-di-GMP riboswitch |
| Q27660426 | Structural determinants underlying photoprotection in the photoactive orange carotenoid protein of cyanobacteria |
| Q37021685 | Structural insight into photoactivation of an adenylate cyclase from a photosynthetic cyanobacterium |
| Q27673555 | Structural insight of a concentration-dependent mechanism by which YdiV inhibits Escherichia coli flagellum biogenesis and motility |
| Q27670606 | Structural insights into the regulatory mechanism of the response regulator RocR from Pseudomonas aeruginosa in cyclic Di-GMP signaling |
| Q39876557 | Structural refinement of a key tryptophan residue in the BLUF photoreceptor AppA by ultraviolet resonance Raman spectroscopy. |
| Q27684664 | Structures of the catalytic EAL domain of the Escherichia coli direct oxygen sensor |
| Q28550530 | Systematic Identification of Cyclic-di-GMP Binding Proteins in Vibrio cholerae Reveals a Novel Class of Cyclic-di-GMP-Binding ATPases Associated with Type II Secretion Systems |
| Q34684486 | Systematic analysis of cyclic di-GMP signalling enzymes and their role in biofilm formation and virulence in Yersinia pestis |
| Q36050221 | The Characterization of Escherichia coli CpdB as a Recombinant Protein Reveals that, besides Having the Expected 3´-Nucleotidase and 2´,3´-Cyclic Mononucleotide Phosphodiesterase Activities, It Is Also Active as Cyclic Dinucleotide Phosphodiesterase |
| Q39078192 | The EAL-like protein STM1697 regulates virulence phenotypes, motility and biofilm formation in Salmonella typhimurium |
| Q27674977 | The Structure of an Unconventional HD-GYP Protein from Bdellovibrio Reveals the Roles of Conserved Residues in this Class of Cyclic-di-GMP Phosphodiesterases |
| Q37894859 | The bacterial second messenger c-di-GMP: mechanisms of signalling |
| Q54286969 | The c-di-GMP phosphodiesterase VmpA absent in Escherichia coli K12 strains affects motility and biofilm formation in the enterohemorrhagic O157:H7 serotype. |
| Q33579968 | The cyclic-di-GMP signaling pathway in the Lyme disease spirochete, Borrelia burgdorferi |
| Q38349818 | The expanding roles of c-di-GMP in the biosynthesis of exopolysaccharides and secondary metabolites. |
| Q35818825 | Three cyanobacteriochromes work together to form a light color-sensitive input system for c-di-GMP signaling of cell aggregation. |
| Q34383878 | Transient conformational fluctuation of TePixD during a reaction |
| Q52668709 | Transmembrane redox control and proteolysis of PdeC, a novel type of c-di-GMP phosphodiesterase. |
| Q37818106 | Tripping the light fantastic: blue-light photoreceptors as examples of environmentally modulated protein-protein interactions |
| Q47693426 | Using Light-Activated Enzymes for Modulating Intracellular c-di-GMP Levels in Bacteria. |
| Q39193399 | Versatile modes of cellular regulation via cyclic dinucleotides. |
| Q28709193 | Why flavins are not competitors of chlorophyll in the evolution of biological converters of solar energy |
| Q37973939 | You've come a long way: c-di-GMP signaling |
| Q42269280 | c-di-GMP signaling regulates E. coli O157:H7 adhesion to colonic epithelium |
Search more.