Crystal structure of importin-α bound to a peptide bearing the nuclear localisation signal from chloride intracellular channel protein 4

scientific article

Crystal structure of importin-α bound to a peptide bearing the nuclear localisation signal from chloride intracellular channel protein 4 is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1111/J.1742-4658.2011.08086.X
P3181OpenCitations bibliographic resource ID3551900
P698PubMed publication ID21388519
P5875ResearchGate publication ID50350587

P50authorBoštjan KobeQ28606730
Paul CurmiQ42648512
Louise J BrownQ56974610
P2093author name stringSamuel N Breit
Stephen J Harrop
Andrew V Mynott
P2860cites workCLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choiceQ24286950
A new role for nuclear transport factor 2 and Ran: nuclear import of CapGQ24312996
Molecular cloning and expression of a chloride ion channel of cell nucleiQ24318734
CLIC4 mediates and is required for Ca2+-induced keratinocyte differentiationQ24320143
MolProbity: all-atom contacts and structure validation for proteins and nucleic acidsQ24684673
Autoinhibition by an internal nuclear localization signal revealed by the crystal structure of mammalian importin alphaQ27617932
Crystallographic analysis of the specific yet versatile recognition of distinct nuclear localization signals by karyopherin alphaQ27622027
Structural basis of recognition of monopartite and bipartite nuclear localization sequences by mammalian importin-alphaQ27622214
Structural basis for the specificity of bipartite nuclear localization sequence binding by importin-alphaQ27640986
The intracellular chloride ion channel protein CLIC1 undergoes a redox-controlled structural transitionQ27642531
Structure and nuclear import function of the C-terminal domain of influenza virus polymerase PB2 subunitQ27643860
S-nitrosylation-induced conformational change in blackfin tuna myoglobinQ27644723
Structural basis for the nuclear import of the human androgen receptorQ27649987
Probing the Specificity of Binding to the Major Nuclear Localization Sequence-binding Site of Importin-  Using Oriented Peptide Library ScreeningQ27660683
Crystallographic Analysis of the Recognition of a Nuclear Localization Signal by the Nuclear Import Factor Karyopherin αQ27764929
Coot: model-building tools for molecular graphicsQ27860505
ESPript: analysis of multiple sequence alignments in PostScriptQ27860708
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Automated macromolecular model building for X-ray crystallography using ARP/wARP version 7Q27860936
Blu-Ice and the Distributed Control System: software for data acquisition and instrument control at macromolecular crystallography beamlinesQ27860952
Refinement of macromolecular structures by the maximum-likelihood methodQ27861011
The CCP4 suite: programs for protein crystallographyQ27861090
Scaling and assessment of data qualityQ27861107
The integration of macromolecular diffraction dataQ27861123
CLIC4 (p64H1) and its putative transmembrane domain form poorly selective, redox-regulated ion channelsQ28299065
Phospholipid scramblase 1 contains a nonclassical nuclear localization signal with unique binding site in importin alphaQ28299257
A short amino acid sequence able to specify nuclear locationQ29547781
Finding nuclear localization signalsQ29614387
Improved amino acid flexibility parametersQ30332782
NLStradamus: a simple Hidden Markov Model for nuclear localization signal predictionQ33475952
S-nitrosylation regulates nuclear translocation of chloride intracellular channel protein CLIC4.Q34025221
Crystal structure of the soluble form of the redox-regulated chloride ion channel protein CLIC4.Q34452667
Visualizing and quantifying molecular goodness-of-fit: small-probe contact dots with explicit hydrogen atomsQ34489213
Identification of S-nitrosylation motifs by site-specific mapping of the S-nitrosocysteine proteome in human vascular smooth muscle cellsQ34624562
CLIC4, skin homeostasis and cutaneous cancer: surprising connectionsQ36795420
Extensive mutagenesis of the nuclear location signal of simian virus 40 large-T antigenQ36900713
Reciprocal modifications of CLIC4 in tumor epithelium and stroma mark malignant progression of multiple human cancersQ40187945
Dissection of a nuclear localization signalQ43508477
CLIC4, an intracellular chloride channel protein, is a novel molecular target for cancer therapyQ53351272
Efficiency of importin alpha/beta-mediated nuclear localization sequence recognition and nuclear import. Differential role of NTF2.Q53895014
P433issue10
P407language of work or nameEnglishQ1860
P921main subjectcrystal structureQ895901
P304page(s)1662-1675
P577publication date2011-03-30
P1433published inFEBS JournalQ1388041
P1476titleCrystal structure of importin-α bound to a peptide bearing the nuclear localisation signal from chloride intracellular channel protein 4
P478volume278

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cites work (P2860)
Q46495548A conserved cationic motif enhances membrane binding and insertion of the chloride intracellular channel protein 1 transmembrane domain
Q54202903APOBEC3B Nuclear Localization Requires two Distinct N-Terminal Domain Surfaces
Q24336527Adaptor protein self-assembly drives the control of a cullin-RING ubiquitin ligase
Q35907430CLIC4 is a tumor suppressor for cutaneous squamous cell cancer.
Q41492916Chloride intracellular channel proteins respond to heat stress in Caenorhabditis elegans.
Q93039507Comparative study of the interactions between fungal transcription factor nuclear localization sequences with mammalian and fungal importin-alpha
Q27316831Design rules for selective binding of nuclear localization signals to minor site of importin α
Q37711718Eag1 K+ Channel: Endogenous Regulation and Functions in Nervous System.
Q28608504Nuclear Localization of the DNA Repair Scaffold XRCC1: Uncovering the Functional Role of a Bipartite NLS
Q40057606Structural Basis for Importin-α Binding of the Human Immunodeficiency Virus Tat.
Q30402034Structural gymnastics of multifunctional metamorphic proteins.
Q27468720The C-terminal 18 Amino Acid Region of Dengue Virus NS5 Regulates its Subcellular Localization and Contains a Conserved Arginine Residue Essential for Infectious Virus Production

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