The crystal structure of human telomeric DNA complexed with berberine: an interesting case of stacked ligand to G-tetrad ratio higher than 1:1

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The crystal structure of human telomeric DNA complexed with berberine: an interesting case of stacked ligand to G-tetrad ratio higher than 1:1 is …
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scholarly articleQ13442814

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P356DOI10.1093/NAR/GKS1001
P932PMC publication ID3592469
P698PubMed publication ID23104378
P5875ResearchGate publication ID232720855

P50authorAnna Rita BiliaQ40259516
Carla BazzicalupiQ42766944
Marta FerraroniQ42889879
Paola GratteriQ49897604
P2093author name stringFrancesca Scheggi
P2860cites workCrystal structure of parallel quadruplexes from human telomeric DNAQ22122125
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Structural basis for binding of porphyrin to human telomeresQ27643721
Structural basis of DNA quadruplex recognition by an acridine drugQ27650536
Topology conservation and loop flexibility in quadruplex-drug recognition: crystal structures of inter- and intramolecular telomeric DNA quadruplex-drug complexesQ27651136
Structural basis of telomeric RNA quadruplex--acridine ligand recognitionQ27666646
X-Ray diffraction analyses of the natural isoquinoline alkaloids Berberine and Sanguinarine complexed with double helix DNA d(CGTACG)Q27667085
Structure of human telomeric DNA in crowded solutionQ27667739
Molecular basis of structure-activity relationships between salphen metal complexes and human telomeric DNA quadruplexesQ27675778
Structural basis for telomeric G-quadruplex targeting by naphthalene diimide ligandsQ27676902
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Features and development of CootQ27861079
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Polymorphic Nucleic Acid Binding of Bioactive Isoquinoline Alkaloids and Their Role in CancerQ34043401
The anti-inflammatory potential of berberine in vitro and in vivoQ34290953
Molecular aspects on the interaction of protoberberine, benzophenanthridine, and aristolochia group of alkaloids with nucleic acid structures and biological perspectivesQ34555144
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G-quadruplexes: targets in anticancer drug design.Q37072655
A hitchhiker's guide to G-quadruplex ligandsQ37080928
Human telomeric G-quadruplex: structures of DNA and RNA sequencesQ37642073
Human telomeric G-quadruplex: the current status of telomeric G-quadruplexes as therapeutic targets in human cancerQ37642075
Interaction of metal complexes with G-quadruplex DNA.Q37760871
Isoquinoline alkaloids and their binding with DNA: calorimetry and thermal analysis applicationsQ37780564
Insight into G-DNA structural polymorphism and folding from sequence and loop connectivity through free energy analysisQ38346238
Synthesis and evaluation of 9-O-substituted berberine derivatives containing aza-aromatic terminal group as highly selective telomeric G-quadruplex stabilizing ligandsQ39845848
9-N-Substituted berberine derivatives: stabilization of G-quadruplex DNA and down-regulation of oncogene c-mycQ39954843
9-Substituted berberine derivatives as G-quadruplex stabilizing ligands in telomeric DNA.Q40118819
G-quadruplex nucleic acids as therapeutic targetsQ41786267
Interaction of human telomeric DNA with N-methyl mesoporphyrin IX.Q41986001
The parallel G-quadruplex structure of vertebrate telomeric repeat sequences is not the preferred folding topology under physiological conditions.Q42727062
Inhibitory effect of isoquinoline alkaloids on movement of second-stage larvae of Toxocara canisQ44260740
Natural and synthetic G-quadruplex interactive berberine derivatives.Q46867706
Following G-quadruplex formation by its intrinsic fluorescence.Q51499661
Mercury CSD 2.0– new features for the visualization and investigation of crystal structuresQ56161326
Shedding Light on the Interaction between TMPyP4 and Human Telomeric QuadruplexesQ57976383
Spectroscopic, Molecular Modeling, and NMR-Spectroscopic Investigation of the Binding Mode of the Natural Alkaloids Berberine and Sanguinarine to Human Telomeric G-Quadruplex DNAQ58061968
G-Quadruplexes from Human Telomeric DNA: How Many Conformations in PEG Containing Solutions?Q59133300
Binding properties of human telomeric quadruplex multimers: A new route for drug designQ59171424
Anthelmintic activity of berberine hydrochloride against Syphacia obvelata in miceQ68287036
Binding of berberine to human telomeric quadruplex - spectroscopic, calorimetric and molecular modeling studiesQ81615700
Interaction of berberine, palmatine, coralyne, and sanguinarine to quadruplex DNA: a comparative spectroscopic and calorimetric studyQ83331779
Kinetic and thermodynamic control of G-quadruplex foldingQ84563247
P275copyright licenseCreative Commons Attribution-NonCommercial 3.0 UnportedQ18810331
P6216copyright statuscopyrightedQ50423863
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectcrystal structureQ895901
P304page(s)632-8
P577publication date2013-01-07
P1433published inNucleic Acids ResearchQ135122
P1476titleThe crystal structure of human telomeric DNA complexed with berberine: an interesting case of stacked ligand to G-tetrad ratio higher than 1:1
P478volume41

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