Structural and functional analysis of the yeast N-acetyltransferase Mpr1 involved in oxidative stress tolerance via proline metabolism

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Structural and functional analysis of the yeast N-acetyltransferase Mpr1 involved in oxidative stress tolerance via proline metabolism is …
instance of (P31):
scholarly articleQ13442814

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P819ADS bibcode2013PNAS..11011821N
P356DOI10.1073/PNAS.1300558110
P3181OpenCitations bibliographic resource ID4731842
P932PMC publication ID3718155
P698PubMed publication ID23818613
P5875ResearchGate publication ID244482666

P50authorYoshinori HiranoQ60965574
Takao HibiQ63645109
P2093author name stringToshio Hakoshima
Hiroshi Takagi
Ryo Nasuno
Takafumi Itoh
P2860cites workAzetidine-2-carboxylic acid: a new cyclic imino acid occurring in plantsQ24531875
The structural basis of ordered substrate binding by serotonin N-acetyltransferase: enzyme complex at 1.8 A resolution with a bisubstrate analogQ27618151
Crystal structure of an aminoglycoside 6'-N-acetyltransferase: defining the GCN5-related N-acetyltransferase superfamily foldQ27618744
The crystal structures of Apo and complexed Saccharomyces cerevisiae GNA1 shed light on the catalytic mechanism of an amino-sugar N-acetyltransferaseQ27630892
Aminoglycoside 2'-N-acetyltransferase from Mycobacterium tuberculosis in complex with coenzyme A and aminoglycoside substratesQ27639456
X-ray structure of the AAC(6')-Ii antibiotic resistance enzyme at 1.8 A resolution; examination of oligomeric arrangements in GNAT superfamily membersQ27640518
Crystal structure of mycothiol synthase (Rv0819) fromMycobacterium tuberculosisshows structural homology to the GNAT family of N-acetyltransferasesQ27641884
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Molecular functions of the histone acetyltransferase chaperone complex Rtt109-Vps75Q27653529
Structure of the histone acetyltransferase Hat1: a paradigm for the GCN5-related N-acetyltransferase superfamilyQ27765266
Inference of macromolecular assemblies from crystalline stateQ27860457
Chaperone control of the activity and specificity of the histone H3 acetyltransferase Rtt109.Q27932154
The flavoprotein Tah18-dependent NO synthesis confers high-temperature stress tolerance on yeast cellsQ27933160
Structure and functions of the GNAT superfamily of acetyltransferasesQ28296840
Saccharomyces cerevisiae sigma 1278b has novel genes of the N-acetyltransferase gene superfamily required for L-proline analogue resistanceQ31786182
Engineering of the yeast antioxidant enzyme Mpr1 for enhanced activity and stability.Q33402999
Enhancement of the proline and nitric oxide synthetic pathway improves fermentation ability under multiple baking-associated stress conditions in industrial baker's yeastQ35984698
Functional annotation and kinetic characterization of PhnO from Salmonella entericaQ36832602
Chemical biology of peroxynitrite: kinetics, diffusion, and radicals.Q37408232
Role of the yeast acetyltransferase Mpr1 in oxidative stress: regulation of oxygen reactive species caused by a toxic proline catabolism intermediateQ37494103
The application of the yeast N-acetyltransferase MPR1 gene and the proline analogue L-azetidine-2-carboxylic acid as a selectable marker system for plant transformationQ40932527
Crystallization and preliminary crystallographic analysis of N-acetyltransferase Mpr1 from Saccharomyces cerevisiaeQ42000985
Nitrogenous compounds and nitrogen metabolism in the Liliaceae. 5. The metabolism of azetidine-2-carboxylic acidQ42949914
An antioxidative mechanism mediated by the yeast N-acetyltransferase Mpr1: oxidative stress-induced arginine synthesis and its physiological roleQ43021310
Antioxidant N-acetyltransferase Mpr1/2 of industrial baker's yeast enhances fermentation ability after air-drying stress in bread doughQ43185691
Heterologous expression of Saccharomyces cerevisiae MPR1 gene confers tolerance to ethanol and L: -azetidine-2-carboxylic acid in Hansenula polymorphaQ43228325
MPR1 as a novel selection marker in Saccharomyces cerevisiaeQ43277188
A novel acetyltransferase found in Saccharomyces cerevisiae Sigma1278b that detoxifies a proline analogue, azetidine-2-carboxylic acidQ43736462
Polymorphism of the MPR1 gene required for toxic proline analogue resistance in the Saccharomyces cerevisiae complex speciesQ44246528
Characterization of novel acetyltransferases found in budding and fission yeasts that detoxify a proline analogue, azetidine-2-carboxylic acidQ44449770
Distribution of L-azetidine-2-carboxylate N-acetyltransferase in yeastQ46767577
N-acetyltransferase Mpr1 confers freeze tolerance on Saccharomyces cerevisiae by reducing reactive oxygen speciesQ46792237
The proline metabolism intermediate Δ1-pyrroline-5-carboxylate directly inhibits the mitochondrial respiration in budding yeast.Q52626459
Production of N-acetyl cis-4-hydroxy-L-proline by the yeast N-acetyltransferase Mpr1.Q54336606
Metabolism of L-azetidine-2-carboxylic acid in the alga Cyanidium caldariumQ68818230
N-Acetyltransferase Mpr1 confers ethanol tolerance on Saccharomyces cerevisiae by reducing reactive oxygen speciesQ80044849
P433issue29
P407language of work or nameEnglishQ1860
P304page(s)11821-11826
P577publication date2013-07-01
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titleStructural and functional analysis of the yeast N-acetyltransferase Mpr1 involved in oxidative stress tolerance via proline metabolism
P478volume110

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