FtsZ Protofilaments Use a Hinge-Opening Mechanism for Constrictive Force Generation

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FtsZ Protofilaments Use a Hinge-Opening Mechanism for Constrictive Force Generation is …
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scholarly articleQ13442814

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P356DOI10.1126/SCIENCE.1239248
P8608Fatcat IDrelease_tcb4e26bhrasnhrgwpoqv3mima
P3181OpenCitations bibliographic resource ID3604870
P932PMC publication ID3816583
P698PubMed publication ID23888039
P5875ResearchGate publication ID252325756

P2093author name stringYing Li
Jen Hsin
Kerwyn Casey Huang
Hong-Wei Wang
Sheng Ye
Lingyun Zhao
Yiwen Cheng
Weina Shang
P2860cites workStructure of Mycobacterium tuberculosis FtsZ reveals unexpected, G protein-like conformational switchesQ45040689
Adaptive biasing force method for scalar and vector free energy calculationsQ46830946
The interactions of cell division protein FtsZ with guanine nucleotides.Q46918546
Self-activation of guanosine triphosphatase activity by oligomerization of the bacterial cell division protein FtsZQ73168034
Structural insights into FtsZ protofilament formationQ81042807
Reconstitution of contractile FtsZ rings in liposomesQ24650388
Comparison of simple potential functions for simulating liquid waterQ26778447
Processing of X-ray diffraction data collected in oscillation modeQ26778468
Refined structure of alpha beta-tubulin at 3.5 A resolutionQ27636088
Structural insights into the conformational variability of FtsZQ27648605
Probing FtsZ and tubulin with C8-substituted GTP analogs reveals differences in their nucleotide binding sitesQ27649905
Combined protein construct and synthetic gene engineering for heterologous protein expression and crystallization using Gene ComposerQ27654997
Restoring methicillin-resistant Staphylococcus aureus susceptibility to β-lactam antibioticsQ27678160
Structural reorganization of the bacterial cell-division protein FtsZ from Staphylococcus aureusQ27682149
Crystal structure of the bacterial cell-division protein FtsZQ27748785
VMD: visual molecular dynamicsQ27860554
Likelihood-enhanced fast translation functionsQ27860634
Scalable molecular dynamics with NAMDQ27860718
XtalView/Xfit--A versatile program for manipulating atomic coordinates and electron densityQ27861034
The CCP4 suite: programs for protein crystallographyQ27861090
Extending the treatment of backbone energetics in protein force fields: limitations of gas-phase quantum mechanics in reproducing protein conformational distributions in molecular dynamics simulationsQ29547631
High-resolution model of the microtubuleQ29618379
Nucleotide-dependent conformations of FtsZ dimers and force generation observed through molecular dynamics simulationsQ30519199
Polymerization of Ftsz, a bacterial homolog of tubulin. is assembly cooperative?Q31816073
Activation of cell division protein FtsZ. Control of switch loop T3 conformation by the nucleotide gamma-phosphateQ31888195
Bacterial cell division protein FtsZ assembles into protofilament sheets and minirings, structural homologs of tubulin polymersQ33634552
The polymerization mechanism of the bacterial cell division protein FtsZ.Q33955077
A rapid fluorescence assay for FtsZ assembly indicates cooperative assembly with a dimer nucleusQ34188556
Tethering the Z ring to the membrane through a conserved membrane targeting sequence in FtsA.Q34400717
Tubulin and FtsZ form a distinct family of GTPasesQ34471922
Parallel Generalized Born Implicit Solvent Calculations with NAMD.Q35569847
ftsZ is an essential cell division gene in Escherichia coliQ36146680
Straight and curved conformations of FtsZ are regulated by GTP hydrolysisQ39498382
In vivo characterization of Escherichia coli ftsZ mutants: effects on Z-ring structure and functionQ39794014
Mutants of FtsZ targeting the protofilament interface: effects on cell division and GTPase activityQ41762400
SulA inhibits assembly of FtsZ by a simple sequestration mechanismQ42402954
Polymerization of nucleotide-free, GDP- and GTP-bound cell division protein FtsZ: GDP makes the differenceQ44957915
Overcoming free energy barriers using unconstrained molecular dynamics simulationsQ45005453
P433issue6144
P407language of work or nameEnglishQ1860
P304page(s)392-5
P577publication date2013-07-26
P1433published inScienceQ192864
P1476titleFtsZ Protofilaments Use a Hinge-Opening Mechanism for Constrictive Force Generation
P478volume341

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cites work (P2860)
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Q35126034The Kil peptide of bacteriophage λ blocks Escherichia coli cytokinesis via ZipA-dependent inhibition of FtsZ assembly
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Q28545060Variations in the binding pocket of an inhibitor of the bacterial division protein FtsZ across genotypes and species
Q41941508Whole genome re-sequencing to identify suppressor mutations of mutant and foreign Escherichia coli FtsZ.

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