scholarly article | Q13442814 |
P50 | author | Tim Skern | Q56056868 |
Irina Grishkovskaya | Q57662231 | ||
P2093 | author name string | Euripedes de Almeida Ribeiro | |
Sofiya Fedosyuk | |||
P2860 | cites work | Toll/IL-1 receptor domain-containing adaptor inducing IFN-beta (TRIF) associates with TNF receptor-associated factor 6 and TANK-binding kinase 1, and activates two distinct transcription factors, NF-kappa B and IFN-regulatory factor-3... | Q24297037 |
Functional and structural studies of the vaccinia virus virulence factor N1 reveal a Bcl-2-like anti-apoptotic protein | Q24305049 | ||
Electrostatics of nanosystems: application to microtubules and the ribosome | Q24555224 | ||
Toll-like receptor signalling | Q24570126 | ||
MolProbity: all-atom structure validation for macromolecular crystallography | Q24649111 | ||
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Vaccinia Virus Proteins A52 and B14 Share a Bcl-2–Like Fold but Have Evolved to Inhibit NF-κB rather than Apoptosis | Q27651621 | ||
Structural basis for the multiple interactions of the MyD88 TIR domain in TLR4 signaling | Q27655822 | ||
Crystal structure of Toll-like receptor adaptor MAL/TIRAP reveals the molecular basis for signal transduction and disease protection | Q27672321 | ||
Structural Insights into TIR Domain Specificity of the Bridging Adaptor Mal in TLR4 Signaling | Q27678387 | ||
XDS | Q27860472 | ||
Coot: model-building tools for molecular graphics | Q27860505 | ||
Substructure solution with SHELXD | Q27860593 | ||
Overview of the CCP4 suite and current developments | Q27860782 | ||
Efficient selection for high-expression transfectants with a novel eukaryotic vector | Q27860810 | ||
Automated macromolecular model building for X-ray crystallography using ARP/wARP version 7 | Q27860936 | ||
T-Coffee: A novel method for fast and accurate multiple sequence alignment | Q27860999 | ||
Refinement of macromolecular structures by the maximum-likelihood method | Q27861011 | ||
PRIMUS: a Windows PC-based system for small-angle scattering data analysis | Q57091059 | ||
1H, 13C, and 15N resonance assignment of the TIR domain of human MyD88 | Q58480700 | ||
The dimerization of Pseudomonas putida cytochrome P450cam: practical consequences and engineering of a monomeric enzyme | Q74445725 | ||
IRAK-2 participates in multiple toll-like receptor signaling pathways to NFkappaB via activation of TRAF6 ubiquitination | Q28249343 | ||
TRAM couples endocytosis of Toll-like receptor 4 to the induction of interferon-beta | Q28506630 | ||
Phosphoinositide-mediated adaptor recruitment controls Toll-like receptor signaling | Q28593045 | ||
The family of five: TIR-domain-containing adaptors in Toll-like receptor signalling | Q29615457 | ||
Innate immunity | Q29618949 | ||
Lysine methylation as a routine rescue strategy for protein crystallization | Q29619069 | ||
A dimer of the Toll-like receptor 4 cytoplasmic domain provides a specific scaffold for the recruitment of signalling adaptor proteins | Q33295379 | ||
Kinetics and intracellular location of intramolecular disulfide bond formation mediated by the cytoplasmic redox system encoded by vaccinia virus | Q33664851 | ||
Molecular interaction studies using microscale thermophoresis | Q33980465 | ||
Microscale thermophoresis quantifies biomolecular interactions under previously challenging conditions | Q34319793 | ||
Achieving reliability and high accuracy in automated protein docking: ClusPro, PIPER, SDU, and stability analysis in CAPRI rounds 13-19 | Q34522304 | ||
Vaccinia viruses: vaccines against smallpox and vectors against infectious diseases and tumors. | Q35571248 | ||
Poxviral protein A46 antagonizes Toll-like receptor 4 signaling by targeting BB loop motifs in Toll-IL-1 receptor adaptor proteins to disrupt receptor:adaptor interactions | Q36080307 | ||
Viral infection: an evolving insight into the signal transduction pathways responsible for the innate immune response | Q36246428 | ||
How Toll-like receptors signal: what we know and what we don't know | Q36339101 | ||
The poxvirus protein A52R targets Toll-like receptor signaling complexes to suppress host defense | Q36370571 | ||
Vaccinia virus protein A46R targets multiple Toll-like-interleukin-1 receptor adaptors and contributes to virulence | Q36403362 | ||
Recognition and signaling by toll-like receptors. | Q36527707 | ||
Molecular basis of NF-κB signaling | Q36918115 | ||
Signaling to NF-kappaB by Toll-like receptors | Q37009320 | ||
Viral evasion and subversion of pattern-recognition receptor signalling | Q37319381 | ||
A46R and A52R from vaccinia virus are antagonists of host IL-1 and toll-like receptor signaling. | Q37421291 | ||
The interferon system and vaccinia virus evasion mechanisms | Q37587172 | ||
How vaccinia virus has evolved to subvert the host immune response. | Q37855047 | ||
Innate and adaptive immune responses to viral infection and vaccination | Q37996191 | ||
Poxvirus antagonism of innate immunity by Bcl-2 fold proteins. | Q38058659 | ||
Research methods: Know when your numbers are significant | Q38067061 | ||
DAMMIF, a program for rapid ab-initio shape determination in small-angle scattering | Q39388340 | ||
The vaccinia virus-encoded Bcl-2 homologues do not act as direct Bax inhibitors | Q39455647 | ||
Viral inhibitory peptide of TLR4, a peptide derived from vaccinia protein A46, specifically inhibits TLR4 by directly targeting MyD88 adaptor-like and TRIF-related adaptor molecule | Q39662113 | ||
A molecular mechanism for Toll-IL-1 receptor domain-containing adaptor molecule-1-mediated IRF-3 activation | Q39711054 | ||
Identification of a peptide derived from vaccinia virus A52R protein that inhibits cytokine secretion in response to TLR-dependent signaling and reduces in vivo bacterial-induced inflammation. | Q40455030 | ||
Mapping the IkappaB kinase beta (IKKbeta)-binding interface of the B14 protein, a vaccinia virus inhibitor of IKKbeta-mediated activation of nuclear factor kappaB. | Q41763836 | ||
A poxvirus Bcl-2-like gene family involved in regulation of host immune response: sequence similarity and evolutionary history | Q42717454 | ||
Heme ligand binding properties and intradimer interactions in the full-length sensor protein dos from Escherichia coli and its isolated heme domain. | Q42952015 | ||
A novel inhibitory peptide of Toll-like receptor signaling limits lipopolysaccharide-induced production of inflammatory mediators and enhances survival in mice | Q43692467 | ||
Crystal contacts as nature's docking solutions | Q47863999 | ||
Poxvirus A46 protein binds to TIR domain-containing Mal/TIRAP via an α-helical sub-domain. | Q54065182 | ||
P433 | issue | 6 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | cell biology | Q7141 |
NF-κB | Q411114 | ||
Vaccinia virus | Q1986297 | ||
P304 | page(s) | 3749-3762 | |
P577 | publication date | 2013-12-19 | |
P1433 | published in | Journal of Biological Chemistry | Q867727 |
P1476 | title | Characterization and structure of the vaccinia virus NF-κB antagonist A46 | |
P478 | volume | 289 |
Q41491559 | An in silico approach towards the identification of novel inhibitors of the TLR-4 signaling pathway |
Q89889589 | Leaky scanning translation generates a second A49 protein that contributes to vaccinia virus virulence |
Q50533334 | Modulating Vaccinia Virus Immunomodulators to Improve Immunological Memory. |
Q37296099 | Multiple Bcl-2 family immunomodulators from vaccinia virus regulate MAPK/AP-1 activation |
Q64092200 | NF-κB activation is a turn on for vaccinia virus phosphoprotein A49 to turn off NF-κB activation |
Q33870595 | Structure of vaccinia virus A46, an inhibitor of TLR4 signaling pathway, shows the conformation of VIPER motif |
Q26823990 | Surfing the Protein-Protein Interaction Surface Using Docking Methods: Application to the Design of PPI Inhibitors |
Q34646268 | TRAM is required for TLR2 endosomal signaling to type I IFN induction |
Q41922877 | The Bcl-2 Family in Host-Virus Interactions. |
Q92662243 | The Bcl-2 Family: Ancient Origins, Conserved Structures, and Divergent Mechanisms |
Q36223863 | Vaccinia Virus Immunomodulator A46: A Lipid and Protein-Binding Scaffold for Sequestering Host TIR-Domain Proteins |
Q30370948 | Vaccinia virus protein A49 is an unexpected member of the B-cell Lymphoma (Bcl)-2 protein family |
Q38986293 | Vaccinia virus virulence factor N1 can be ubiquitylated on multiple lysine residues |
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