A phosphatidylinositol transfer protein integrates phosphoinositide signaling with lipid droplet metabolism to regulate a developmental program of nutrient stress-induced membrane biogenesis

scientific article

A phosphatidylinositol transfer protein integrates phosphoinositide signaling with lipid droplet metabolism to regulate a developmental program of nutrient stress-induced membrane biogenesis is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1091/MBC.E13-11-0634
P3181OpenCitations bibliographic resource ID4119299
P932PMC publication ID3937096
P698PubMed publication ID24403601

P50authorEric A. OrtlundQ55476823
Mara C. DuncanQ55743789
Carl J. MousleyQ55834857
Robert C. MurphyQ57083376
Aaron M NeimanQ30502889
Aaron H NileQ42736135
P2093author name stringH Alex Brown
Debra M Eckert
David S Myers
Thomas J Leiker
Brenda R S Temple
Manish C Pathak
Vytas A Bankaitis
Jihui Ren
Pavlina T Ivanova
Kerry S Bloom
Coney Pei-Chen Lin
Jolien Verdaasdonk
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A highly redundant gene network controls assembly of the outer spore wall in S. cerevisiaeQ27931126
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Lipid droplets are functionally connected to the endoplasmic reticulum in Saccharomyces cerevisiae.Q53239116
Characterization of lipid particles of the yeast, Saccharomyces cerevisiaeQ72581652
The gene encoding the phosphatidylinositol transfer protein is essential for cell growth.Q27932378
Nonclassical PITPs activate PLD via the Stt4p PtdIns-4-kinase and modulate function of late stages of exocytosis in vegetative yeast.Q27932380
The lipodystrophy protein seipin is found at endoplasmic reticulum lipid droplet junctions and is important for droplet morphologyQ27932399
Cdk1/Cdc28-dependent activation of the major triacylglycerol lipase Tgl4 in yeast links lipolysis to cell-cycle progressionQ27933027
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A lecithin cholesterol acyltransferase-like gene mediates diacylglycerol esterification in yeast.Q27933801
The ubiquitin-like (UBX)-domain-containing protein Ubx2/Ubxd8 regulates lipid droplet homeostasisQ27933872
Prospore membrane formation defines a developmentally regulated branch of the secretory pathway in yeastQ27934009
SAC1-like domains of yeast SAC1, INP52, and INP53 and of human synaptojanin encode polyphosphoinositide phosphatasesQ27934132
Identification of a novel family of nonclassic yeast phosphatidylinositol transfer proteins whose function modulates phospholipase D activity and Sec14p-independent cell growthQ27934214
The Saccharomyces cerevisiae SEC14 gene encodes a cytosolic factor that is required for transport of secretory proteins from the yeast Golgi complexQ27935633
Identification of domains required for developmentally regulated SNARE function in Saccharomyces cerevisiaeQ27936460
Fld1p, a functional homologue of human seipin, regulates the size of lipid droplets in yeastQ27937464
Erv14 family cargo receptors are necessary for ER exit during sporulation in Saccharomyces cerevisiaeQ27937949
Dtrlp, a multidrug resistance transporter of the major facilitator superfamily, plays an essential role in spore wall maturation in Saccharomyces cerevisiae.Q27938079
An essential role for a phospholipid transfer protein in yeast Golgi functionQ27938456
Mutations in the CDP-choline pathway for phospholipid biosynthesis bypass the requirement for an essential phospholipid transfer proteinQ27938693
The yeast lipin orthologue Pah1p is important for biogenesis of lipid dropletsQ27939057
Phospholipase D and the SNARE Sso1p are necessary for vesicle fusion during sporulation in yeastQ27939389
The lipid droplet is an important organelle for hepatitis C virus productionQ28131709
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COPI complex is a regulator of lipid homeostasisQ28474150
The life of lipid dropletsQ28749823
Phospholipase D activity is required for suppression of yeast phosphatidylinositol transfer protein defectsQ28776473
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The anaphase promoting complex targeting subunit Ama1 links meiotic exit to cytokinesis during sporulation in Saccharomyces cerevisiaeQ30485258
Functional genomic screen reveals genes involved in lipid-droplet formation and utilizationQ30489849
Glycerophospholipid identification and quantitation by electrospray ionization mass spectrometryQ33303514
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Perilipins, ADRP, and other proteins that associate with intracellular neutral lipid droplets in animal cellsQ33650749
Phospholipase D signaling is essential for meiosis.Q33651595
The Sec14 superfamily and mechanisms for crosstalk between lipid metabolism and lipid signalingQ33712549
Quantitative analysis of glycerophospholipids by LC-MS: acquisition, data handling, and interpretationQ33935579
Commitment to meiosis in Saccharomyces cerevisiae: involvement of the SPO14 geneQ33959237
ARF1 and GBF1 generate a PI4P-enriched environment supportive of hepatitis C virus replicationQ34168582
Thematic review series: glycerolipids. DGAT enzymes and triacylglycerol biosynthesisQ34817393
Crystallization and preliminary X-ray diffraction analysis of Sfh3, a member of the Sec14 protein superfamily.Q35539154
Role of PAT proteins in lipid metabolismQ36055789
An intimate collaboration between peroxisomes and lipid bodiesQ36117598
Development of the spore wall during ascospore formation in Saccharomyces cerevisiaeQ36191557
Nile red: a selective fluorescent stain for intracellular lipid dropletsQ36211849
Relocalization of phospholipase D activity mediates membrane formation during meiosisQ36254911
Perilipin A is essential for the translocation of hormone-sensitive lipase during lipolytic activationQ36323578
Yeast Cdc42 functions at a late step in exocytosis, specifically during polarized growth of the emerging budQ36380043
Hepatitis C virus utilizes lipid droplet for production of infectious virusQ36580492
A proposed model of fat packaging by exchangeable lipid droplet proteinsQ36589548
Separation of cellular nonpolar neutral lipids by normal-phase chromatography and analysis by electrospray ionization mass spectrometryQ36631783
Regulation of triglyceride metabolism. I. Eukaryotic neutral lipid synthesis: "Many ways to skin ACAT or a DGAT".Q36649458
Cellular spelunking: exploring adipocyte caveolaeQ36818964
Sorting signals within the Saccharomyces cerevisiae sporulation-specific dityrosine transporter, Dtr1p, C terminus promote Golgi-to-prospore membrane transportQ36939035
A role for lipid droplets in inter-membrane lipid trafficQ37178208
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PAT proteins, an ancient family of lipid droplet proteins that regulate cellular lipid stores.Q37435661
Cellular lipid droplets and hepatitis C virus life cycleQ37700052
The obligate intracellular pathogen Chlamydia trachomatis targets host lipid droplets.Q37861620
PERILIPIN-dependent control of lipid droplet structure and fat storage in DrosophilaQ42479119
Mammalian diseases of phosphatidylinositol transfer proteins and their homologsQ42736093
Perilipin A mediates the reversible binding of CGI-58 to lipid droplets in 3T3-L1 adipocytesQ42826631
Gene expression and evolution of antifungal drug resistanceQ43128288
Lipid bodies in oxidized LDL-induced foam cells are leukotriene-synthesizing organelles: a MCP-1/CCL2 regulated phenomenon.Q45941888
A role for phospholipase D (Pld1p) in growth, secretion, and regulation of membrane lipid synthesis in yeastQ47922035
SGXPro: a parallel workflow engine enabling optimization of program performance and automation of structure determination.Q48604817
Microscopic analysis of lipid droplet metabolism and dynamics in yeast.Q50610011
Dynamic activity of lipid droplets: protein phosphorylation and GTP-mediated protein translocation.Q51796352
Functional studies on native and mutated forms of perilipins. A role in protein kinase A-mediated lipolysis of triacylglycerols.Q51840956
P4510describes a project that usesImageJQ1659584
P433issue5
P921main subjectcell biologyQ7141
Phosphatidylinositol transporter YNL231CQ27551399
P304page(s)712-27
P577publication date2014-03-01
P1433published inMolecular Biology of the CellQ2338259
P1476titleA phosphatidylinositol transfer protein integrates phosphoinositide signaling with lipid droplet metabolism to regulate a developmental program of nutrient stress-induced membrane biogenesis
P478volume25

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