Ocular transient receptor potential channel function in health and disease

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Ocular transient receptor potential channel function in health and disease is …
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review articleQ7318358
scholarly articleQ13442814

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P6179Dimensions Publication ID1035445804
P356DOI10.1186/S12886-015-0135-7
P3181OpenCitations bibliographic resource ID4441983
P932PMC publication ID4895786
P698PubMed publication ID26818117
P5875ResearchGate publication ID287390371

P2093author name stringYuka Okada
Shizuya Saika
Stefan Mergler
Peter S. Reinach
P2860cites workIncreased expression of the transient receptor potential cation channel 6 gene in patients with primary open-angle glaucomaQ86557231
Autoantibodies to transient receptor potential cation channel, subfamily M, member 1 in a Japanese patient with melanoma-associated retinopathyQ87173848
Isoform-specific inhibition of TRPC4 channel by phosphatidylinositol 4,5-bisphosphateQ40019222
Dual role of the TRPV4 channel as a sensor of flow and osmolality in renal epithelial cellsQ40094040
A high-threshold heat-activated channel in cultured rat dorsal root ganglion neurons resembles TRPV2 and is blocked by gadoliniumQ40114604
Calcium regulation by thermo- and osmosensing transient receptor potential vanilloid channels (TRPVs) in human conjunctival epithelial cells.Q50517284
Induction of voltage-dependent sodium channels by in vitro differentiation of human retinoblastoma cells.Q51653628
Polyunsaturated fatty acids activate the Drosophila light-sensitive channels TRP and TRPL.Q52568167
Blockade of the intermediate-conductance Ca(2+)-activated K+ channel inhibits the angiogenesis induced by epidermal growth factor in the treatment of corneal alkali burn.Q53116830
Expression and regulation of antimicrobial peptide psoriasin (S100A7) at the ocular surface and in the lacrimal apparatus.Q54374186
Influence of temperature on corneas stored in culture medium. A comparative study using functional and morphological methodsQ73111290
The contribution of TRPV4-mediated calcium signaling to calcium homeostasis in endothelial cellsQ80573495
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Channelopathies converge on TRPV4Q82659974
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RetinoblastomaQ84672125
How cold is it? TRPM8 and TRPA1 in the molecular logic of cold sensationQ21223670
Whole-exome sequencing identifies mutations in GPR179 leading to autosomal-recessive complete congenital stationary night blindnessQ21710708
Metabotropic glutamate receptor 6 signaling enhances TRPM1 calcium channel function and increases melanin content in human melanocytesQ24321293
The capsaicin receptor: a heat-activated ion channel in the pain pathwayQ24322558
Anandamide and vanilloid TRPV1 receptorsQ24672354
From mechanosensitivity to inflammatory responses: new players in the pathology of glaucomaQ26864408
TRPM6 forms the Mg2+ influx channel involved in intestinal and renal Mg2+ absorptionQ28212198
Molecular characterization of the Drosophila trp locus: a putative integral membrane protein required for phototransductionQ28246876
The mammalian melastatin-related transient receptor potential cation channels: an overviewQ28250890
Abnormal Electroretinogram from a Drosophila MutantQ28252075
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Coupling of photoexcited rhodopsin to inositol phospholipid hydrolysis in fly photoreceptorsQ28360942
The menthol receptor TRPM8 is the principal detector of environmental coldQ28508677
Mutation of the melastatin-related cation channel, TRPM3, underlies inherited cataract and glaucomaQ28541568
Identification of a cold receptor reveals a general role for TRP channels in thermosensationQ28580334
TRPM1 is required for the depolarizing light response in retinal ON-bipolar cellsQ28591911
Regulation of cell death: the calcium-apoptosis linkQ29615554
An introduction to TRP channelsQ29615753
Transient receptor potential vanilloid 1 activation induces inflammatory cytokine release in corneal epithelium through MAPK signalingQ40131820
TRPV6 mediates capsaicin-induced apoptosis in gastric cancer cells--Mechanisms behind a possible new "hot" cancer treatmentQ40172527
Direct activation of the ion channel TRPA1 by Ca2+.Q40177823
Contribution of TRPM8 channels to cold transduction in primary sensory neurons and peripheral nerve terminals.Q40202804
TRPV1b overexpression negatively regulates TRPV1 responsiveness to capsaicin, heat and low pH in HEK293 cellsQ40224259
Transient receptor potential (TRP) protein 7 acts as a G protein-activated Ca2+ channel mediating angiotensin II-induced myocardial apoptosisQ40256202
Ca(v)3.1 splice variant expression during neuronal differentiation of Y-79 retinoblastoma cellsQ40282908
TRPV4 exhibits a functional role in cell-volume regulationQ40415614
Functional control of cold- and menthol-sensitive TRPM8 ion channels by phosphatidylinositol 4,5-bisphosphate.Q40457196
EGF suppresses hydrogen peroxide induced Ca2+ influx by inhibiting L-type channel activity in cultured human corneal endothelial cells.Q40465867
The principle of temperature-dependent gating in cold- and heat-sensitive TRP channelsQ40526282
Involvement of TRPM7 in cell growth as a spontaneously activated Ca2+ entry pathway in human retinoblastoma cells.Q40529906
A novel TRPM2 isoform inhibits calcium influx and susceptibility to cell deathQ40669622
Heat-evoked activation of TRPV4 channels in a HEK293 cell expression system and in native mouse aorta endothelial cellsQ40700786
A mammalian capacitative calcium entry channel homologous to Drosophila TRP and TRPL.Q41078512
Ionic channels in corneal endotheliumQ41224043
Choroidal atrophy in a patient with paraneoplastic retinopathy and anti-TRPM1 antibodyQ41860529
Role of melastatin-related transient receptor potential channel TRPM1 in the retina: Clues from horses and mice.Q41876357
Differential expression and localization of transient receptor potential vanilloid 1 in rabbit and human eyes.Q42439011
Impairment of corneal epithelial wound healing in a TRPV1-deficient mouseQ42458157
Ocular surface wetness is regulated by TRPM8-dependent cold thermoreceptors of the cornea.Q42479895
TRPV channels mediate temperature-sensing in human corneal endothelial cellsQ43118660
Functional expression of transient receptor potential vanilloid 3 (TRPV3) in corneal epithelial cells: involvement in thermosensation and wound healingQ43269027
The role of apoptosis in the pathogenesis of Fuchs endothelial dystrophy of the corneaQ43799684
Calcium influx induced by activation of receptor tyrosine kinases in SV40-transfected human corneal endothelial cellsQ43838337
T-Type calcium channel alpha1G and alpha1H subunits in human retinoblastoma cells and their loss after differentiationQ44046161
The Ca(2+) channel antagonists mibefradil and pimozide inhibit cell growth via different cytotoxic mechanismsQ44072135
Mechanotransduction channels of the trabecular meshworkQ44509142
Immunolocalization of TRPC channel subunits 1 and 4 in the chicken retinaQ44682048
2-aminoethoxydiphenyl borate activates and sensitizes the heat-gated ion channel TRPV3.Q44919605
The fibroblast growth factor receptors, FGFR-1 and FGFR-2, mediate two independent signalling pathways in human retinal pigment epithelial cellsQ46723874
Novel mechanism of massive photoreceptor degeneration caused by mutations in the trp gene of Drosophila.Q47070695
Low-voltage-activated calcium channels in human retinoblastoma cellsQ48395823
Heat-evoked activation of the ion channel, TRPV4.Q48526032
Peripheral and central distribution of TRPV1, substance P and CGRP of rat corneal neurons.Q48605588
Camphor modulates TRPV3 cation channels activity by interacting with critical pore-region cysteine residues.Q48625876
TRP channelsQ29616673
Changes in corneal endothelial apical junctional protein organization after corneal cold storageQ30817014
The National Cancer Data Base report on cutaneous and noncutaneous melanoma: a summary of 84,836 cases from the past decade. The American College of Surgeons Commission on Cancer and the American Cancer SocietyQ31995716
Transient Receptor Potential Channels in Endothelium: Solving the Calcium Entry Puzzle?Q33338297
Transient receptor potential (TRP) channels: a clinical perspectiveQ33562143
TRPC4 knockdown suppresses epidermal growth factor-induced store-operated channel activation and growth in human corneal epithelial cellsQ33896548
Ultrastructural localization and expression of TRPM1 in the human retinaQ34012483
Epidermal growth factor receptor transactivation by the cannabinoid receptor (CB1) and transient receptor potential vanilloid 1 (TRPV1) induces differential responses in corneal epithelial cellsQ34079507
The trp gene is essential for a light-activated Ca2+ channel in Drosophila photoreceptors.Q34234955
The TRP superfamily of cation channelsQ34397161
Impaired thermosensation in mice lacking TRPV3, a heat and camphor sensor in the skin.Q34399994
Physiology, phylogeny, and functions of the TRP superfamily of cation channelsQ34467912
TRPV4.Q34600626
TRPV1 Activation Is Required for Hypertonicity-Stimulated Inflammatory Cytokine Release in Human Corneal Epithelial CellsQ34646774
Pharmacology of vanilloid transient receptor potential cation channelsQ34965016
TRPV1 potentiates TGFβ-induction of corneal myofibroblast development through an oxidative stress-mediated p38-SMAD2 signaling loopQ35009747
The history of the Drosophila TRP channel: the birth of a new channel superfamilyQ35012564
The polymodal ion channel transient receptor potential vanilloid 4 modulates calcium flux, spiking rate, and apoptosis of mouse retinal ganglion cellsQ35030683
TRPV1 involvement in inflammatory tissue fibrosis in miceQ35071389
Role of Ca2+ signaling in the regulation of endothelial permeabilityQ35127956
Thermosensory and nonthermosensory isoforms of Drosophila melanogaster TRPA1 reveal heat-sensor domains of a thermoTRP ChannelQ35752664
Ocular dryness excites two classes of corneal afferent neurons implicated in basal tearing in rats: involvement of transient receptor potential channels.Q35787569
Thermosensation and painQ35884812
Mucolipin 1: endocytosis and cation channel--a reviewQ35966839
G-protein-mediated inhibition of the Trp channel TRPM1 requires the Gβγ dimerQ36001431
Drosophila visual transductionQ36007831
TRPV4 in porcine lens epithelium regulates hemichannel-mediated ATP release and Na-K-ATPase activityQ36041917
Function and pharmacology of TRPM cation channelsQ36103564
The mechanosensitive nature of TRPV channelsQ36134906
TRPV4 as osmosensor: a transgenic approachQ36160926
TRP channels: a TR(I)P through a world of multifunctional cation channelsQ36192009
TRP channels in diseaseQ36217258
TRP channels: an overviewQ36228455
TRP channel gene expression in the mouse retina.Q36280955
Menthol activation of corneal cool cells induces TRPM8-mediated lacrimation but not nociceptive responses in rodentsQ36318296
Gβ3 is required for normal light ON responses and synaptic maintenanceQ36338293
Ion channels in cell proliferation and apoptotic cell deathQ36345950
Clinical relevance of ion channels for diagnosis and therapy of cancerQ36345960
TRPV1: contribution to retinal ganglion cell apoptosis and increased intracellular Ca2+ with exposure to hydrostatic pressure.Q36547404
Functional TRPV1 expression in human corneal fibroblastsQ36565378
Advances in corneal preservationQ36652121
TRP channels of the pancreatic beta cellQ36705027
Dry eye syndromesQ36722830
The human corneal endothelium: new insights into electrophysiology and ion channelsQ36796488
The vanilloid receptor TRPV1: 10 years from channel cloning to antagonist proof-of-conceptQ36803753
TRP channels in mechanosensation: direct or indirect activation?Q36856424
Ca2+ channels in retinal pigment epithelial cells regulate vascular endothelial growth factor secretion rates in health and disease.Q37110107
Calcium homeostasis in human melanocytes: role of transient receptor potential melastatin 1 (TRPM1) and its regulation by ultraviolet lightQ37338925
Absence of transient receptor potential vanilloid-1 accelerates stress-induced axonopathy in the optic projectionQ37603758
Transient receptor potential channelopathiesQ37686351
Pharmacological modulation of diacylglycerol-sensitive TRPC3/6/7 channelsQ37798861
TRP channels of islets.Q37835168
Transient receptor potential (TRP) gene superfamily encoding cation channelsQ37836175
Uveal melanoma: trends in incidence, treatment, and survivalQ37894345
Ion channels and transporters in cancer. 6. Vascularizing the tumor: TRP channels as molecular targetsQ37915101
Targeting calcium channels to block tumor vascularizationQ38005195
TRP channelsQ38111283
TRPM1.Q38206431
Functional and physiopathological implications of TRP channels.Q38456330
Drosophila in vision research. The Friedenwald LectureQ38574728
Thyronamine induces TRPM8 channel activation in human conjunctival epithelial cellsQ38933704
Functional significance of thermosensitive transient receptor potential melastatin channel 8 (TRPM8) expression in immortalized human corneal endothelial cells.Q39077388
Calcium regulation by temperature-sensitive transient receptor potential channels in human uveal melanoma cellsQ39089165
Cannabinoid receptor 1 suppresses transient receptor potential vanilloid 1-induced inflammatory responses to corneal injuryQ39246714
Altered calcium regulation by thermosensitive transient receptor potential channels in etoposide-resistant WERI-Rb1 retinoblastoma cellsQ39425591
Characterization of transient receptor potential vanilloid channel 4 (TRPV4) in human corneal endothelial cellsQ39458657
Thermosensitive transient receptor potential channels in human corneal epithelial cellsQ39555890
Heat-sensitive TRPV channels in retinal pigment epithelial cells: regulation of VEGF-A secretionQ39694506
Calcium elevation in mouse pancreatic beta cells evoked by extracellular human islet amyloid polypeptide involves activation of the mechanosensitive ion channel TRPV4.Q39946656
TRPM8 activation suppresses cellular viability in human melanomaQ39975199
Dependence of regulatory volume decrease on transient receptor potential vanilloid 4 (TRPV4) expression in human corneal epithelial cells.Q40000125
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P407language of work or nameEnglishQ1860
P921main subjectmembrane proteinQ423042
transport proteinQ2111029
eye diseaseQ3041498
P5008on focus list of Wikimedia projectScienceSourceQ55439927
P304page(s)153
P577publication date2015-12-17
P1433published inBMC OphthalmologyQ15765692
P1476titleOcular transient receptor potential channel function in health and disease
P478volume15 Suppl 1

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cites work (P2860)
Q573004863-Iodothyronamine Activates a Set of Membrane Proteins in Murine Hypothalamic Cell Lines
Q28552858Borneol Is a TRPM8 Agonist that Increases Ocular Surface Wetness
Q40062999Neuropathic symptoms of the ocular surface: dryness, pain, and itch
Q93178733TRPM8 Channels and Dry Eye
Q26738621TRPV1: A Target for Rational Drug Design
Q99730948The role of TRPV4 channels in ocular function and pathologies
Q59812970Vascular Endothelial Growth Factor (VEGF) Induced Downstream Responses to Transient Receptor Potential Vanilloid 1 (TRPV1) and 3-Iodothyronamine (3-TAM) in Human Corneal Keratocytes

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