Structural details of the binding of guanosine diphosphate to elongation factor Tu from E. coli as studied by X-ray crystallography

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Structural details of the binding of guanosine diphosphate to elongation factor Tu from E. coli as studied by X-ray crystallography is …
instance of (P31):
scholarly articleQ13442814

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P932PMC publication ID554514
P698PubMed publication ID3908095

P2093author name stringNyborg J
Clark BF
Thirup S
la Cour TF
P2860cites workNucleotide sequence of aEuglena gracilischloroplast genome region coding for the elongation factor Tu; evidence for a spliced mRNAQ24604961
Molecular cloning and sequence determination of the nuclear gene coding for mitochondrial elongation factor Tu of Saccharomyces cerevisiaeQ27939841
Structural patterns in globular proteinsQ28252376
Electron-paramagnetic-resonance studies of manganese(II) complexes with elongation factor Tu from Bacillus stearothermophilus. Observation of a GTP hydrolysis intermediate state complexQ36586586
Polypeptide chain elongation factor 1 alpha (EF-1 alpha) from yeast: nucleotide sequence of one of the two genes for EF-1 alpha from Saccharomyces cerevisiaeQ36602230
Sequence of the initiation factor IF2 gene: unusual protein features and homologies with elongation factors.Q37580219
Phosphate-binding sequences in nucleotide-binding proteinsQ39494819
Regional homology in GTP-binding proto-oncogene products and elongation factorsQ40200769
Structural requirements of the GDP binding site of elongation factor TuQ40764508
High resolution X-ray crystallographic analysis of a modified form of the elongation factor Tu:Guanosine diphosphate complexQ40981501
Homologies in the primary structure of GTP-binding proteins: the nucleotide-binding site of EF-Tu and p21.Q41562639
The primary structure of elongation factor EF-1 alpha from the brine shrimp ArtemiaQ41571645
The preparation of thiophosphate analogs of GDP and their interaction with EF-TuQ41681521
Spectroscopic studies of the nucleotide binding site of elongation factor Tu from Escherichia coli. An approach to characterizing the elementary steps of the elongation cycle of protein biosynthesisQ42262693
Guanine nucleotide-binding and autophosphorylating activities associated with the p21src protein of Harvey murine sarcoma virusQ45105517
The alpha-helix dipole and the properties of proteinsQ45281613
The reactions of the sulfhydryl groups on the elongation factors Tu and Ts.Q47740490
Homology between human bladder carcinoma oncogene product and mitochondrial ATP-synthaseQ59086195
Predicted nucleotide-binding properties of p21 protein and its cancer-associated variantQ59098604
Stereochemistry of the elongation factor Tu . GTP complexQ59663148
The Structure of the EF-Tu . GDP . Me2+ ComplexQ59663156
Elongation factor T from Bacillus stearothermophilus and Escherichia coli. Purification and some properties of EF-Tu and EF-Ts from Bacillus stearothermophilusQ67475238
Studies on the polypeptide elongation factors form E. coli. VI. Characterization of sulfhydryl groups in EF-Tu and EF-TsQ69361642
X-ray determination of the GDP-binding site of Escherichia coli elongation factor Tu by substitution with ppGppQ70153170
Structural features of the GDP binding site of elongation factor Tu from Escherichia coli as determined by x-ray diffractionQ70175772
The primary structure of elongation factor G from Escherichia coli. A complete amino acid sequenceQ70230845
Modification of amino groups in EF-Tu.GTP and the ternary complex EF-Tu.GTP.valyl-tRNAValQ70489154
Interaction of Escherichia coli EF-Tu.GTP and EF-Tu.GDP with analogues of the 3' terminus of aminoacyl-tRNAQ72135964
The complete amino-acid sequence of elongation factor Tu from Escherichia coliQ72148461
EPR studies of the Mn(II) complex with elongation factor Tu and GDP Identification of oxygen ligands to Mn(II) by observation of 17O superhyperfine couplingQ72909105
Electron paramagnetic resonance studies of MN(II) complexes with myosin subfragment 1 and oxygen 17-labeled ligandsQ72923414
P433issue9
P407language of work or nameEnglishQ1860
P921main subjectEscherichia coliQ25419
X-ray crystallographyQ826582
P304page(s)2385-2388
P577publication date1985-09-01
P1433published inThe EMBO JournalQ1278554
P1476titleStructural details of the binding of guanosine diphosphate to elongation factor Tu from E. coli as studied by X-ray crystallography
P478volume4

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cites work (P2860)
Q37408568A GTP-binding protein of Escherichia coli has homology to yeast RAS proteins
Q30426704A proposed architecture for the central domain of the bacterial enhancer-binding proteins based on secondary structure prediction and fold recognition
Q39895623A single amino acid substitution in elongation factor Tu disrupts interaction between the ternary complex and the ribosome
Q42284161ATP is a cofactor of the Upf1 protein that modulates its translation termination and RNA binding activities
Q35930280Altering the conserved nucleotide binding motif in the Salmonella typhimurium MutS mismatch repair protein affects both its ATPase and mismatch binding activities
Q40744665Aluminum interaction with phosphoinositide-associated signal transduction
Q35615941Amino acid sequence of mammalian elongation factor 2 deduced from the cDNA sequence: homology with GTP-binding proteins
Q33889534An ATP-ADP switch in MuB controls progression of the Mu transposition pathway
Q41265251An NTP-binding motif is the most conserved sequence in a highly diverged monophyletic group of proteins involved in positive strand RNA viral replication
Q35930129An enlarged largest subunit of Plasmodium falciparum RNA polymerase II defines conserved and variable RNA polymerase domains
Q35908923Autophosphorylation of nucleoside diphosphate kinase from Myxococcus xanthus
Q42159732Biochemical characteristics of a rice (Oryza sativa L., IR36) G-protein alpha-subunit expressed in Escherichia coli
Q27936486Biochemical properties of the ras-related YPT protein in yeast: a mutational analysis.
Q28592967Characterization of mSelB, a novel mammalian elongation factor for selenoprotein translation
Q48298374Characterization of the str operon genes from Spirulina platensis and their evolutionary relationship to those of other prokaryotes
Q40806950Codon-dependent conformational change of elongation factor Tu preceding GTP hydrolysis on the ribosome.
Q36757146Comparison of the Tu elongation factors from Staphylococcus aureus and Escherichia coli: possible basis for elfamycin insensitivity
Q70264589Comparison of the predicted structure for the activated form of the P21 protein with the X-ray crystal structure
Q67288412Complete nucleotide sequences of seven eubacterial genes coding for the elongation factor Tu: functional, structural and phylogenetic evaluations
Q45105290Computer-aided active-site-directed modeling of the herpes simplex virus 1 and human thymidine kinase
Q34630861Consensus topography in the ATP binding site of the simian virus 40 and polyomavirus large tumor antigens
Q37420187Drosophila stimulatory G protein alpha subunit activates mammalian adenylyl cyclase but interacts poorly with mammalian receptors: implications for receptor-G protein interaction
Q40485134Effects of the ?F508 mutation on the structure, function, and folding of the first nucleotide-binding domain of CFTR
Q24633187Elongation in translation as a dynamic interaction among the ribosome, tRNA, and elongation factors EF-G and EF-Tu
Q39501095Escherichia coli DNA polymerase III tau- and gamma-subunit conserved residues required for activity in vivo and in vitro
Q42570121Expression of p21 proteins in Escherichia coli and stereochemistry of the nucleotide-binding site
Q40530157Functional implications related to the gene structure of the elongation factor EF-Tu from Halobacterium marismortui
Q34607799GTP-binding domain: three consensus sequence elements with distinct spacing
Q27940268Genetic and biochemical characterization of mutations in the ATPase and helicase regions of the Upf1 protein
Q36108067Glucitol induction in Bacillus subtilis is mediated by a regulatory factor, GutR
Q24648387Identification of cDNA encoding an additional alpha subunit of a human GTP-binding protein: expression of three alpha i subtypes in human tissues and cell lines
Q35614371Identification of effector residues and a neutralizing epitope of Ha-ras-encoded p21.
Q33997185Identification of essential amino acids in the Azorhizobium caulinodans fucosyltransferase NodZ.
Q34985438Identification of the gene encoding the mitochondrial elongation factor G in mammals
Q40510090Influence of a mutation in the putative nucleotide binding site of the nitrogen regulatory protein NTRC on its positive control function
Q24323138Interferon-induced guanylate-binding proteins lack an N(T)KXD consensus motif and bind GMP in addition to GDP and GTP
Q43206224Isoleucine:RNA sites with associated coding sequences
Q24634693Mechanism and regulation of eukaryotic protein synthesis
Q36179458Molecular analysis of the Escherichia coli recO gene
Q80608657Molecular cloning of the black tiger shrimp (Penaeus monodon) elongation factor 2 (EF-2): sequence analysis and its expression on the ovarian maturation stage
Q33842411Molecular model of the G protein alpha subunit based on the crystal structure of the HRAS protein
Q24675718Multiple protein structure alignment
Q35990517Mutation of lysine-48 to arginine in the yeast RAD3 protein abolishes its ATPase and DNA helicase activities but not the ability to bind ATP.
Q33566253Mutational analysis of SEC4 suggests a cyclical mechanism for the regulation of vesicular traffic
Q35616455Mutations of the ras gene product p21 that abolish guanine nucleotide binding
Q35241401Neuronal expression of a newly identified Drosophila melanogaster G protein alpha 0 subunit
Q27936901Novel G-protein complex whose requirement is linked to the translational status of the cell.
Q72188135Phylogenetic relationships of Bacteria based on comparative sequence analysis of elongation factor Tu and ATP-synthase beta-subunit genes
Q34599393Prokaryotic and eukaryotic RNA polymerases have homologous core subunits
Q34622043Properties of a genetically engineered G domain of elongation factor Tu.
Q24643469Protein translocation across the ER requires a functional GTP binding site in the alpha subunit of the signal recognition particle receptor
Q24630231Ras-catalyzed hydrolysis of GTP: a new perspective from model studies
Q27674619Refined crystal structure of the triphosphate conformation of H-ras p21 at 1.35 A resolution: implications for the mechanism of GTP hydrolysis
Q34244273Rep protein of tomato yellow leaf curl geminivirus has an ATPase activity required for viral DNA replication.
Q38302842Rhizobium meliloti NodP and NodQ form a multifunctional sulfate-activating complex requiring GTP for activity
Q36709185SAS1 and SAS2, GTP-binding protein genes in Dictyostelium discoideum with sequence similarities to essential genes in Saccharomyces cerevisiae
Q36222336Saccharomyces cerevisiae and Schizosaccharomyces pombe contain a homologue to the 54-kD subunit of the signal recognition particle that in S. cerevisiae is essential for growth
Q42628895Sequence analysis of the second largest subunit of tomato RNA polymerase II.
Q40391660Sequence and identification of the nucleotide binding site for the elongation factor Tu from Thermus thermophilus HB8.
Q40450644Structure and expression of elongation factor 1 alpha in tomato.
Q27622305Structure of the fMet-tRNAfMet-binding domain of B.stearothermophilus initiation factor IF2
Q30420492Structure-based identification and clustering of protein families and superfamilies
Q38346597Structure-function relationships in the GTP binding domain of EF-Tu: mutation of Val20, the residue homologous to position 12 in p21
Q33264100The Trypanosoma cruzi neuraminidase contains sequences similar to bacterial neuraminidases, YWTD repeats of the low density lipoprotein receptor, and type III modules of fibronectin
Q36685367The conserved helicase motifs of the herpes simplex virus type 1 origin-binding protein UL9 are important for function
Q33635485The highly conserved amino acid sequence motif Tyr-Gly-Asp-Thr-Asp-Ser in alpha-like DNA polymerases is required by phage phi 29 DNA polymerase for protein-primed initiation and polymerization
Q27638673The large subunit of initiation factor aIF2 is a close structural homologue of elongation factors.
Q40468679The movement protein of cowpea mosaic virus binds GTP and single-stranded nucleic acid in vitro.
Q77576610The role of GTP-binding proteins in mechanochemical movements of microorganisms and their potential to form filamentous structures
Q36656301The six conserved helicase motifs of the UL5 gene product, a component of the herpes simplex virus type 1 helicase-primase, are essential for its function
Q28325351Three-dimensional structure of p21 in the active conformation and analysis of an oncogenic mutant
Q38353711Transcription in the early diverging eukaryote Trichomonas vaginalis: an unusual RNA polymerase II and alpha-amanitin-resistant transcription of protein-coding genes
Q42641979Two new members of the OmpR superfamily detected by homology to a sensor-binding core domain
Q24635818Two related superfamilies of putative helicases involved in replication, recombination, repair and expression of DNA and RNA genomes
Q54698709Unusual organization of a ribosomal protein operon in the plastid genome of Cryptomonas phi: evolutionary considerations.
Q38345731Unusually strong immunological cross-reaction between elongation factor Tu of Escherichia coli and Bacillus subtilis
Q38306984Viral proteins containing the purine NTP-binding sequence pattern
Q36615800YeiR: a metal-binding GTPase from Escherichia coli involved in metal homeostasis

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