scholarly article | Q13442814 |
P356 | DOI | 10.1016/S1074-5521(98)90632-9 |
P698 | PubMed publication ID | 9545432 |
P50 | author | Dana E Vanderwall | Q58894938 |
P2093 | author name string | J H Toney | |
J W Kozarich | |||
D L Pompliano | |||
S H Olson | |||
J K Wu | |||
S K Grant | |||
W J May | |||
P M Fitzgerald | |||
J G Sundelof | |||
G G Hammond | |||
K A Cleary | |||
N Grover-Sharma | |||
P2860 | cites work | Novel method for detection of beta-lactamases by using a chromogenic cephalosporin substrate | Q24564458 |
The 3-D structure of a zinc metallo-beta-lactamase from Bacillus cereus reveals a new type of protein fold | Q24598128 | ||
Crystal structure of the wide-spectrum binuclear zinc beta-lactamase from Bacteroides fragilis | Q27733390 | ||
Unanticipated inhibition of the metallo-beta-lactamase from Bacteroides fragilis by 4-morpholineethanesulfonic acid (MES): a crystallographic study at 1.85-A resolution | Q27757196 | ||
X-ray structure of the ZnII beta-lactamase from Bacteroides fragilis in an orthorhombic crystal form | Q27765648 | ||
Imipenem/cilastatin. A reappraisal of its antibacterial activity, pharmacokinetic properties and therapeutic efficacy | Q28188300 | ||
Imipenem/Cilastatin | Q29400850 | ||
FLOG: a system to select 'quasi-flexible' ligands complementary to a receptor of known three-dimensional structure | Q30420637 | ||
Metabolism of thienamycin and related carbapenem antibiotics by the renal dipeptidase, dehydropeptidase | Q34056981 | ||
Flexibases: a way to enhance the use of molecular docking methods | Q34319987 | ||
Methicillin-resistant Staphylococcus aureus: a consensus review of the microbiology, pathogenesis, and epidemiology with implications for prevention and management | Q34361837 | ||
Characterization of the metal-binding sites of the beta-lactamase from Bacteroides fragilis | Q36820128 | ||
High-yield expression, purification, and characterization of active, soluble Bacteroides fragilis metallo-beta-lactamase, CcrA. | Q38347224 | ||
Inhibition of metallo-beta-lactamases by a series of mercaptoacetic acid thiol ester derivatives | Q39783479 | ||
Carbapenem-hydrolyzing beta-lactamases | Q39783563 | ||
Purification and characterization of human renal dehydropeptidase I. | Q39818046 | ||
Molecular aspects of methicillin resistance in Staphylococcus aureus | Q40740211 | ||
Beta-lactam resistance in anaerobic bacteria: a review | Q41134735 | ||
Advances in automated docking applied to human immunodeficiency virus type 1 protease | Q45784087 | ||
CLIX: A search algorithm for finding novel ligands capable of binding proteins of known three‐dimensional structure | Q52434109 | ||
Uptake of glycine from L-alanylglycine into renal brush border vesicles. | Q54561219 | ||
Automated docking with grid-based energy evaluation | Q56005218 | ||
Potent, orally active imidazo[4,5-b]pyridine-based angiotensin II receptor antagonists | Q67977564 | ||
Stereochemically restrained refinement of macromolecular structures | Q69806243 | ||
Renal dipeptidase: Localization and inhibition | Q70714567 | ||
Tetrazole and carboxylate groups of angiotensin receptor antagonists bind to the same subsite by different mechanisms | Q71670902 | ||
Molecular evolution of bacterial beta-lactam resistance | Q71824485 | ||
Simultaneous resistance to metronidazole, co-amoxiclav, and imipenem in clinical isolate of Bacteroides fragilis | Q72226523 | ||
Nonpeptide angiotensin II antagonists derived from 1H-pyrazole-5-carboxylates and 4-aryl-1H-imidazole-5-carboxylates | Q72622138 | ||
Antimicrobial resistance in Bacteroides | Q72812806 | ||
Containment of antibiotic resistance | Q74331515 | ||
P433 | issue | 4 | |
P921 | main subject | Bacteroides fragilis | Q221817 |
P304 | page(s) | 185-196 | |
P577 | publication date | 1998-04-01 | |
P1433 | published in | Chemistry and Biology | Q15758410 |
P1476 | title | Antibiotic sensitization using biphenyl tetrazoles as potent inhibitors of Bacteroides fragilis metallo-beta-lactamase | |
P478 | volume | 5 |
Q48143694 | 1,2,4-Triazole-3-thione Compounds as Inhibitors of Dizinc Metallo-β-lactamases |
Q36294078 | 2-Substituted 4,5-dihydrothiazole-4-carboxylic acids are novel inhibitors of metallo-β-lactamases |
Q38119956 | An Update on the Status of Potent Inhibitors of Metallo-β-Lactamases |
Q44426206 | Analysis of the importance of the metallo-beta-lactamase active site loop in substrate binding and catalysis |
Q73679146 | Antifungal properties of substituted 1-phenyl-5-mercaptotetrazoles and their oxidation product, 5-bis-(1-phenyltetrazolyl)disulfide |
Q38620756 | Aromatic interactions at the ligand-protein interface: Implications for the development of docking scoring functions |
Q41832679 | Assay platform for clinically relevant metallo-β-lactamases |
Q44124582 | Binding of D- and L-captopril inhibitors to metallo-beta-lactamase studied by polarizable molecular mechanics and quantum mechanics |
Q34579901 | Biochemical, mechanistic, and spectroscopic characterization of metallo-β-lactamase VIM-2. |
Q42816243 | Bulgecin A: a novel inhibitor of binuclear metallo-beta-lactamases |
Q46236865 | Carbamylmethyl Mercaptoacetate Thioether: A Novel Scaffold for the Development of L1 Metallo-β-lactamase Inhibitors |
Q39471986 | Carbapenem derivatives as potential inhibitors of various beta-lactamases, including class B metallo-beta-lactamases. |
Q34158563 | Computational analysis of pathogen-borne metallo β-lactamases reveals discriminating structural features between B1 types |
Q36953146 | Conformational changes in the metallo-beta-lactamase ImiS during the catalytic reaction: an EPR spectrokinetic study of Co(II)-spin label interactions |
Q36522851 | Conformational dynamics of metallo-β-lactamase CcrA during catalysis investigated by using DEER spectroscopy |
Q35801593 | Crystal Structure of DIM-1, an Acquired Subclass B1 Metallo-β-Lactamase from Pseudomonas stutzeri |
Q35847179 | Crystallization and preliminary X-ray analysis of the subclass B3 metallo-β-lactamase SMB-1 that confers carbapenem resistance |
Q37731521 | Current challenges in antimicrobial chemotherapy: focus on ß-lactamase inhibition |
Q87421586 | Diaryl-substituted azolylthioacetamides: Inhibitor discovery of New Delhi metallo-β-lactamase-1 (NDM-1) |
Q36522810 | Dilution of dipolar interactions in a spin-labeled, multimeric metalloenzyme for DEER studies |
Q58641878 | Diversity and Proliferation of Metallo-β-Lactamases: a Clarion Call for Clinically Effective Metallo-β-Lactamase Inhibitors |
Q45162110 | Docking and scoring of metallo-beta-lactamases inhibitors |
Q43512278 | Docking molecules by families to increase the diversity of hits in database screens: computational strategy and experimental evaluation |
Q28752557 | Evolving carbapenemases: can medicinal chemists advance one step ahead of the coming storm? |
Q38196443 | Fragment-based inhibitor discovery against β-lactamase |
Q27639017 | Identification of a series of tricyclic natural products as potent broad-spectrum inhibitors of metallo-beta-lactamases |
Q54060436 | In vitro antibacterial activity and mechanism of action of J-111,225, a novel 1beta-methylcarbapenem, against transferable IMP-1 metallo-beta-lactamase producers. |
Q30684727 | Inactivation of Aeromonas hydrophila metallo-beta-lactamase by cephamycins and moxalactam |
Q46617087 | Loss of enzyme activity during turnover of the Bacillus cereus beta-lactamase catalysed hydrolysis of beta-lactams due to loss of zinc ion. |
Q33745008 | Metallo-beta-lactamase: structure and mechanism |
Q33755227 | Metallo-beta-lactamases: the quiet before the storm? |
Q38060809 | Metallo-β-lactamase structure and function |
Q57971140 | Metallo-β-lactamases: does it take two to tango? |
Q44190840 | Molecular dynamics simulations of the dinuclear zinc-beta-lactamase from Bacteroides fragilis complexed with imipenem |
Q33974530 | Molecular strategies for overcoming antibiotic resistance in bacteria |
Q39652530 | N-arylsulfonyl hydrazones as inhibitors of IMP-1 metallo-beta-lactamase |
Q35053125 | New ways to treat bacterial infections |
Q43666445 | Novel mechanism of hydrolysis of therapeutic beta-lactams by Stenotrophomonas maltophilia L1 metallo-beta-lactamase |
Q34211132 | Overcoming antimicrobial resistance by targeting resistance mechanisms |
Q37775511 | Photochemical transformations of tetrazole derivatives: applications in organic synthesis. |
Q24802987 | Probing substrate binding to metallo-beta-lactamase L1 from Stenotrophomonas maltophilia by using site-directed mutagenesis |
Q54505676 | Probing the specificity of the subclass B3 FEZ-1 metallo-beta-lactamase by site-directed mutagenesis. |
Q38683817 | Progress toward inhibitors of metallo-β-lactamases |
Q39537109 | Purification and biochemical characterization of the VIM-1 metallo-beta-lactamase |
Q43152746 | Role of a solvent-exposed tryptophan in the recognition and binding of antibiotic substrates for a metallo-beta-lactamase |
Q57945566 | Sigmatropic rearrangements in 5-allyloxytetrazoles |
Q27680023 | Solution structures of the Bacillus cereus metallo-β-lactamase BcII and its complex with the broad spectrum inhibitor R -thiomandelic acid |
Q39476451 | Standard numbering scheme for class B beta-lactamases |
Q53706201 | Structural and Kinetic Studies of the Potent Inhibition of Metallo-β-lactamases by 6-Phosphonomethylpyridine-2-carboxylates. |
Q44894410 | Structural determinants of substrate binding to Bacillus cereus metallo-beta-lactamase |
Q73049539 | Structure-activity relationships of biphenyl tetrazoles as metallo-beta-lactamase inhibitors |
Q60195800 | Structure-based discovery and in-parallel optimization of novelcompetitive inhibitors of thymidylate synthase |
Q27632353 | Succinic acids as potent inhibitors of plasmid-borne IMP-1 metallo-beta-lactamase |
Q73022449 | Synthesis and SAR of thioester and thiol inhibitors of IMP-1 metallo-beta-lactamase |
Q48905941 | Synthesis of (2-mercaptoacetyl)-L-[2-14 C]tryptophan as a selective metallo-β-lactamase inhibitor via [2-14 C]indole based on chiral pool strategy |
Q42826676 | Synthesis, anticandidal activity and cytotoxicity of some tetrazole derivatives. |
Q58733176 | Synthesis, single crystal analysis, biological and docking evaluation of tetrazole derivatives |
Q38121932 | Targeting metallo-β-lactamase enzymes in antibiotic resistance |
Q61802827 | Tetrazoles via Multicomponent Reactions |
Q26866583 | Tetrazolium compounds: synthesis and applications in medicine |
Q27640947 | The 1.5-A structure of Chryseobacterium meningosepticum zinc beta-lactamase in complex with the inhibitor, D-captopril |
Q39729538 | The Role of Active Site Flexible Loops in Catalysis and of Zinc in Conformational Stability of Bacillus cereus 569/H/9 β-Lactamase |
Q44425130 | The inhibitor thiomandelic acid binds to both metal ions in metallo-beta-lactamase and induces positive cooperativity in metal binding |
Q41249257 | The multifaceted roles of antibiotics and antibiotic resistance in nature |
Q43743302 | Thiomandelic acid, a broad spectrum inhibitor of zinc beta-lactamases: kinetic and spectroscopic studies |
Q24646623 | Three decades of beta-lactamase inhibitors |
Q57946539 | Vibrational spectra and structure of 1-phenyltetrazole and 5-chloro-1-phenyltetrazole |
Q64914465 | Virtual Screening and Experimental Testing of B1 Metallo-β-lactamase Inhibitors. |
Q34074695 | beta-Lactamase epidemiology and the utility of established and novel beta-lactamase inhibitors |
Search more.