| scholarly article | Q13442814 |
| review article | Q7318358 |
| P356 | DOI | 10.1146/ANNUREV.PHARMTOX.41.1.261 |
| P698 | PubMed publication ID | 11264458 |
| P2093 | author name string | G Powis | |
| W R Montfort | |||
| P433 | issue | 1 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 261-95 | |
| P577 | publication date | 2001-01-01 | |
| P1433 | published in | Annual Review of Pharmacology and Toxicology | Q567365 |
| P1476 | title | Properties and biological activities of thioredoxins | |
| P478 | volume | 41 |
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| Q44572770 | Absolute gene expression patterns of thioredoxin and glutaredoxin redox systems in mouse |
| Q46874754 | An investigation into the serum thioredoxin, superoxide dismutase, malondialdehyde, and advanced oxidation protein products in patients with breast cancer |
| Q34056376 | Angiogenesis inhibitors: current strategies and future prospects |
| Q34009906 | Antigen-presenting dendritic cells provide the reducing extracellular microenvironment required for T lymphocyte activation |
| Q35822221 | Antioxidant enzymes and redox regulating thiol proteins in malignancies of human lung |
| Q42509598 | Basal and angiotensin II-inhibited neuronal delayed-rectifier K+ current are regulated by thioredoxin |
| Q91792214 | CD40 induces renal cell carcinoma-specific differential regulation of TRAF proteins, ASK1 activation and JNK/p38-mediated, ROS-dependent mitochondrial apoptosis |
| Q38789891 | CYP2E1 Sensitizes the Liver to LPS- and TNF α-Induced Toxicity via Elevated Oxidative and Nitrosative Stress and Activation of ASK-1 and JNK Mitogen-Activated Kinases |
| Q33961287 | Carbamoylating activity associated with the activation of the antitumor agent laromustine inhibits angiogenesis by inducing ASK1-dependent endothelial cell death |
| Q28395366 | Characterization of a Thioredoxin-1 Gene from Taenia solium and Its Encoding Product |
| Q35170644 | Characterization of human thioredoxin-like 2. A novel microtubule-binding thioredoxin expressed predominantly in the cilia of lung airway epithelium and spermatid manchette and axoneme |
| Q28570641 | Cloning and characterization of rat spermatid protein SSP411: a thioredoxin-like protein |
| Q23910065 | Cloning and developmental analysis of murid spermatid-specific thioredoxin-2 (SPTRX-2), a novel sperm fibrous sheath protein and autoantigen |
| Q37707861 | Converting disulfide bridges in native peptides to stable methylene thioacetals |
| Q27663622 | Crystal structure of human thioredoxin revealing an unraveled helix and exposedS-nitrosation site |
| Q89540112 | Crystal structure of thioredoxin 1 from Cryptococcus neoformans at 1.8 Å resolution shows unexpected plasticity of the loop preceding the catalytic site |
| Q36010528 | Cynoglossus semilaevis thioredoxin: a reductase and an antioxidant with immunostimulatory property |
| Q34103330 | Delivering the message: epimorphin and mammary epithelial morphogenesis |
| Q35027866 | Depletion of cytosolic or mitochondrial thioredoxin increases CYP2E1-induced oxidative stress via an ASK-1-JNK1 pathway in HepG2 cells |
| Q47886605 | Differential inhibition of high and low Mr thioredoxin reductases of parasites by organotelluriums supports the concept that low Mr thioredoxin reductases are good drug targets |
| Q41839448 | Effects of insulin-like growth factor 1 on glutathione S-transferases and thioredoxin in growth hormone receptor knockout mice |
| Q36748734 | Evolution and cellular function of monothiol glutaredoxins: involvement in iron-sulphur cluster assembly. |
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| Q36203156 | Extracellular thioredoxin levels are increased in patients with acute lung injury. |
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| Q33859467 | Functional specialization of Chlamydomonas reinhardtii cytosolic thioredoxin h1 in the response to alkylation-induced DNA damage |
| Q42081344 | Glutathione and thioredoxin type 1 cooperatively denitrosate HepG2 cells-derived cytosolic S-nitrosoproteins |
| Q89069255 | Gold-Based Medicine: A Paradigm Shift in Anti-Cancer Therapy? |
| Q57696989 | HIF-1 inhibitors as anti-cancer therapy |
| Q34163208 | HIF-independent regulation of thioredoxin reductase 1 contributes to the high levels of reactive oxygen species induced by hypoxia |
| Q46004073 | Hepatocellular carcinoma in Txnip-deficient mice. |
| Q36219726 | Histone deacetylase inhibitors: insights into mechanisms of lethality |
| Q33282459 | Human TRP14 gene homologue from amphioxus Branchiostoma belcheri: identification, evolution, expression and functional characterization |
| Q30332092 | Human spermatid-specific thioredoxin-1 (Sptrx-1) is a two-domain protein with oxidizing activity. |
| Q42722446 | Identification and pathway mapping of furan target proteins reveal mitochondrial energy production and redox regulation as critical targets of furan toxicity |
| Q48035078 | Identification of acid-base catalytic residues of high-Mr thioredoxin reductase from Plasmodium falciparum |
| Q21263139 | Identification of genes differentially expressed in T cells following stimulation with the chemokines CXCL12 and CXCL10 |
| Q33382549 | Identification of human thioredoxin as a novel IFN-gamma-induced factor: mechanism of induction and its role in cytokine production |
| Q47739141 | Increased expression of thioredoxin-1 in human colorectal cancer is associated with decreased patient survival |
| Q39986849 | Increased mitochondrial thioredoxin 2 potentiates N-ethylmaleimide-induced cytotoxicity |
| Q38353655 | Increased thioredoxin-1 inhibits SSAT expression in MCF-7 human breast cancer cells |
| Q35040845 | Infusion of Trx-1-overexpressing hucMSC prolongs the survival of acutely irradiated NOD/SCID mice by decreasing excessive inflammatory injury |
| Q40331679 | Insights into Trx1, TRP14, and Prx1 homologs of Paralichthys olivaceus: molecular profiles and transcriptional responses to immune stimulations |
| Q37697032 | Intermolecular disulfide bond to modulate protein function as a redox-sensing switch |
| Q80094198 | Investigation of TXNIP (thioredoxin-interacting protein) and TRX (thioredoxin) genes for growth-related traits in pigs |
| Q35149589 | Involvement of metformin and AMPK in the radioresponse and prognosis of luminal versus basal-like breast cancer treated with radiotherapy |
| Q47068703 | Lifespan decrease in a Caenorhabditis elegans mutant lacking TRX-1, a thioredoxin expressed in ASJ sensory neurons |
| Q43034833 | Mitochondrial thioredoxin in regulation of oxidant-induced cell death |
| Q42226736 | Modulation of ASK1 expression during overexpression of Trx and HSP70 in stressed fish liver mitochondria |
| Q44120318 | Molecular and enzymatic characterisation of Schistosoma mansoni thioredoxin |
| Q34619502 | Molecular pharmacology and antitumor activity of palmarumycin-based inhibitors of thioredoxin reductase |
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| Q27670644 | NMR Structure of Carcinoscorpius rotundicauda Thioredoxin-related Protein 16 and Its Role in Regulating Transcription Factor NF- B Activity |
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| Q27930254 | Nuclear monothiol glutaredoxins of Saccharomyces cerevisiae can function as mitochondrial glutaredoxins |
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| Q44635825 | Overexpression of thioredoxin reductase 1 regulates NF‐κB activation |
| Q46685693 | Overexpression of yeast thioredoxin TRX2 reduces p53-mediated cell death in yeast |
| Q40647018 | Oxidation of nuclear thioredoxin during oxidative stress |
| Q39625412 | Oxidation of thiols and modification of redox-sensitive signaling in human lung epithelial cells exposed to Pseudomonas pyocyanin |
| Q36803025 | Oxidoreductase regulation of Kv currents in rat ventricle |
| Q42817098 | Paeoniflorin isolated from Paeonia lactiflora attenuates osteoblast cytotoxicity induced by antimycin A. |
| Q37240258 | Potent activity of indolequinones against human pancreatic cancer: identification of thioredoxin reductase as a potential target |
| Q35754188 | Potential role of recombinant adeno-associated virus human thioredoxin-PR39 in cell and vascular protection against hypoxia |
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| Q35773665 | Pro-Oxidant Activity of Amine-Pyridine-Based Iron Complexes Efficiently Kills Cancer and Cancer Stem-Like Cells |
| Q44322876 | Purification and characterization of delta3Trx-1, a splicing variant of human thioredoxin-1 lacking exon 3. |
| Q33691222 | Quantitative mass spectrometry of diabetic kidney tubules identifies GRAP as a novel regulator of TGF-beta signaling |
| Q27015003 | Quantitative redox biology: an approach to understand the role of reactive species in defining the cellular redox environment |
| Q24630110 | Reactivity of thioredoxin as a protein thiol-disulfide oxidoreductase |
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| Q38202479 | Revisiting an age-old question regarding oxidative stress |
| Q33296324 | Rod-derived Cone Viability Factor-2 is a novel bifunctional-thioredoxin-like protein with therapeutic potential |
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| Q35832440 | Serum thioredoxin is a diagnostic marker for hepatocellular carcinoma |
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| Q44239927 | Silencing of the thioredoxin gene in Trypanosoma brucei brucei |
| Q36028185 | Silencing thioredoxin induces liver cancer cell senescence under hypoxia |
| Q24295125 | Spermatocyte/spermatid-specific thioredoxin-3, a novel Golgi apparatus-associated thioredoxin, is a specific marker of aberrant spermatogenesis |
| Q34104400 | Sptrx-2, a fusion protein composed of one thioredoxin and three tandemly repeated NDP-kinase domains is expressed in human testis germ cells |
| Q27640170 | Structural and functional characterization of the Pseudomonas hydroperoxide resistance protein Ohr. |
| Q24303332 | Structural basis of cellular redox regulation by human TRP14 |
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| Q44519300 | The Pseudomonas secretory product pyocyanin inhibits catalase activity in human lung epithelial cells |
| Q36151496 | The Redox System in C. elegans, a Phylogenetic Approach |
| Q33233126 | The antitumor thioredoxin-1 inhibitor PX-12 (1-methylpropyl 2-imidazolyl disulfide) decreases thioredoxin-1 and VEGF levels in cancer patient plasma |
| Q37848718 | The cytoprotective role of the Keap1-Nrf2 pathway |
| Q23910066 | The mammalian testis-specific thioredoxin system |
| Q40677508 | The nonclassic secretion of thioredoxin is not sensitive to redox state |
| Q34576816 | The quiescin sulfhydryl oxidase (hQSOX1b) tunes the expression of resistin-like molecule alpha (RELM-α or mFIZZ1) in a wheat germ cell-free extract |
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| Q39932236 | Thioredoxin overexpression modulates remodeling factors in stress responses to cigarette smoke. |
| Q36312905 | Thioredoxin reductase is inhibited by the carbamoylating activity of the anticancer sulfonylhydrazine drug laromustine. |
| Q43841731 | Thioredoxin stimulates MMP-9 expression, de-regulates the MMP-9/TIMP-1 equilibrium and promotes MMP-9 dependent invasion in human MDA-MB-231 breast cancer cells |
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| Q38348470 | Thioredoxin-mediated redox control of the transcription factor Sp1 and regulation of the thioredoxin gene promoter. |
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| Q35083415 | Up-regulation of the redox mediators thioredoxin and apurinic/apyrimidinic excision (APE)/Ref-1 in hypoxic microregions of invasive cervical carcinomas, mapped using multispectral, wide-field fluorescence image analysis |
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