FAP1, a homologue of human transcription factor NF-X1, competes with rapamycin for binding to FKBP12 in yeast

scientific article

FAP1, a homologue of human transcription factor NF-X1, competes with rapamycin for binding to FKBP12 in yeast is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1046/J.1365-2958.2000.02105.X
P698PubMed publication ID10998178
P5875ResearchGate publication ID12325433

P2093author name stringM N Hall
J Kunz
M Deuter-Reinhard
A Loeschmann
P2860cites workDNA sequencing with chain-terminating inhibitorsQ22066207
Specific interaction of type I receptors of the TGF-beta family with the immunophilin FKBP-12Q24305896
Two cytoplasmic candidates for immunophilin action are revealed by affinity for a new cyclophilin: one in the presence and one in the absence of CsAQ24306828
Point mutations in v-Myb disrupt a cyclophilin-catalyzed negative regulatory mechanismQ24313422
A novel cysteine-rich sequence-specific DNA-binding protein interacts with the conserved X-box motif of the human major histocompatibility complex class II genes via a repeated Cys-His domain and functions as a transcriptional repressorQ24337320
The 25-kDa FK506-binding protein is localized in the nucleus and associates with casein kinase II and nucleolinQ24561774
A comprehensive set of sequence analysis programs for the VAXQ26778432
A novel genetic system to detect protein-protein interactionsQ27860915
The TOR signalling pathway controls nuclear localization of nutrient-regulated transcription factorsQ27929794
FK 506-binding protein proline rotamase is a target for the immunosuppressive agent FK 506 in Saccharomyces cerevisiaeQ27931207
PIK-related kinases: DNA repair, recombination, and cell cycle checkpointsQ27934828
All cyclophilins and FK506 binding proteins are, individually and collectively, dispensable for viability in Saccharomyces cerevisiaeQ27937279
A human peptidyl-prolyl isomerase essential for regulation of mitosisQ28117639
Getting started with yeastQ28131602
5-Fluoroorotic acid as a selective agent in yeast molecular geneticsQ28131614
A mammalian protein targeted by G1-arresting rapamycin-receptor complexQ28243712
FKBP12 binds the inositol 1,4,5-trisphosphate receptor at leucine-proline (1400-1401) and anchors calcineurin to this FK506-like domainQ28252789
Calcineurin associated with the inositol 1,4,5-trisphosphate receptor-FKBP12 complex modulates Ca2+ fluxQ28270468
Targets for Cell Cycle Arrest by the Immunosuppressant Rapamycin in YeastQ28277565
Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexesQ28277749
Immunopharmacology of rapamycinQ28285198
RAFT1: a mammalian protein that binds to FKBP12 in a rapamycin-dependent fashion and is homologous to yeast TORsQ28286431
Cyclophilin A and FKBP12 interact with YY1 and alter its transcriptional activityQ28288097
FAP48, a new protein that forms specific complexes with both immunophilins FKBP59 and FKBP12. Prevention by the immunosuppressant drugs FK506 and rapamycinQ28299106
Isolation of a protein target of the FKBP12-rapamycin complex in mammalian cellsQ28305483
Calcineurin phosphatase activity in T lymphocytes is inhibited by FK 506 and cyclosporin AQ28316169
RAPT1, a mammalian homolog of yeast Tor, interacts with the FKBP12/rapamycin complexQ28368227
Cardiac defects and altered ryanodine receptor function in mice lacking FKBP12Q28594463
Immunophilin FK506 binding protein associated with inositol 1,4,5-trisphosphate receptor modulates calcium fluxQ28609357
Additional modules for versatile and economical PCR-based gene deletion and modification in Saccharomyces cerevisiaeQ29546523
Protein folding in the cellQ29547792
Target of rapamycin in yeast, TOR2, is an essential phosphatidylinositol kinase homolog required for G1 progressionQ29616821
Rapamycin-modulated transcription defines the subset of nutrient-sensitive signaling pathways directly controlled by the Tor proteinsQ29617782
Vectors for the inducible overexpression of glutathione S-transferase fusion proteins in yeastQ29618547
Identification of calcineurin as a key signalling enzyme in T-lymphocyte activationQ29620223
The TOR signaling cascade regulates gene expression in response to nutrientsQ29620801
The mechanism of action of cyclosporin A and FK506Q30014847
Target of rapamycin (TOR): balancing the opposing forces of protein synthesis and degradationQ33540082
Dominant missense mutations in a novel yeast protein related to mammalian phosphatidylinositol 3-kinase and VPS34 abrogate rapamycin cytotoxicityQ34358570
Regulation of MHC class II genes: lessons from a diseaseQ34389691
TOR2 is required for organization of the actin cytoskeleton in yeastQ35930168
Asymmetrical blockade of the Ca2+ release channel (ryanodine receptor) by 12-kDa FK506 binding proteinQ35950019
Starvation induces vacuolar targeting and degradation of the tryptophan permease in yeastQ36301450
A homolog of human transcription factor NF-X1 encoded by the Drosophila shuttle craft gene is required in the embryonic central nervous systemQ36556749
RNA- and single-stranded DNA-binding (SSB) proteins expressed during Drosophila melanogaster oogenesis: a homolog of bacterial and eukaryotic mitochondrial SSBsQ36752505
TOR mutations confer rapamycin resistance by preventing interaction with FKBP12-rapamycin.Q38289137
FKBP12 physically and functionally interacts with aspartokinase in Saccharomyces cerevisiaeQ40023567
Protein folding. Prolyl isomerases join the foldQ40935542
A signaling pathway to translational controlQ41073792
Mechanism of TGFbeta receptor inhibition by FKBP12Q41101968
Stabilization of calcium release channel (ryanodine receptor) function by FK506-binding proteinQ41467443
TOR signalling and control of cell growthQ41678494
Confirmation of the existence of a third family among peptidyl-prolyl cis/trans isomerases. Amino acid sequence and recombinant production of parvulinQ48079055
FKBP-12 recognition is dispensable for signal generation by type I transforming growth factor-beta receptors.Q52521102
The immunophilin FKBP12 functions as a common inhibitor of the TGF beta family type I receptors.Q52549447
Characterization of an exchange reaction between soluble FKBP-12 and the FKBP.ryanodine receptor complex. Modulation by FKBP mutants deficient in peptidyl-prolyl isomerase activity.Q54014128
Characterization of the Interaction of FKBP12 with the Transforming Growth Factor-β Type I Receptorin VivoQ57267089
Immunosuppressant Target Protein FKBP12 Is Required for P-Glycoprotein Function in YeastQ57371744
Calcineurin mediates inhibition by FK506 and cyclosporin of recovery from alpha-factor arrest in yeastQ59064521
P433issue6
P407language of work or nameEnglishQ1860
P921main subjectsirolimusQ32089
Fap1p YNL023CQ27552076
P304page(s)1480-93
P577publication date2000-09-01
P1433published inMolecular MicrobiologyQ6895967
P1476titleFAP1, a homologue of human transcription factor NF-X1, competes with rapamycin for binding to FKBP12 in yeast
P478volume37

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cites work (P2860)
Q37336719NFX1-123 and human papillomavirus 16E6 increase Notch expression in keratinocytes
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Q41054780Recurrent background mutations in WHI2 impair proteostasis and degradation of misfolded cytosolic proteins in Saccharomyces cerevisiae
Q44875173Transcript profiling of the phytotoxic response of wheat to the Fusarium mycotoxin deoxynivalenol
Q52813151Yeast Gup1(2) Proteins Are Homologues of the Hedgehog Morphogens Acyltransferases HHAT(L): Facts and Implications.