| scholarly article | Q13442814 |
| P2093 | author name string | A Varshavsky | |
| B Bartel | |||
| K Madura | |||
| R J Dohmen | |||
| P2860 | cites work | The Role of Radiation (rad) Genes in Meiotic Recombination in Yeast | Q24533493 |
| The human ubiquitin carrier protein E2(Mr = 17,000) is homologous to the yeast DNA repair gene RAD6 | Q24556553 | ||
| Inhibition of the N-end rule pathway in living cells | Q24564179 | ||
| Purification of a RAS-responsive adenylyl cyclase complex from Saccharomyces cerevisiae by use of an epitope addition method | Q24631695 | ||
| A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae | Q27860636 | ||
| UBA 1: an essential yeast gene encoding ubiquitin-activating enzyme | Q27931184 | ||
| The yeast cell cycle gene CDC34 encodes a ubiquitin-conjugating enzyme | Q27933363 | ||
| The yeast DNA repair gene RAD6 encodes a ubiquitin-conjugating enzyme | Q27933609 | ||
| Cloning and functional analysis of the arginyl-tRNA-protein transferase gene ATE1 of Saccharomyces cerevisiae | Q27935532 | ||
| The recognition component of the N-end rule pathway | Q27937878 | ||
| Ubiquitin-conjugating enzymes UBC4 and UBC5 mediate selective degradation of short-lived and abnormal proteins | Q27939145 | ||
| New yeast-Escherichia coli shuttle vectors constructed with in vitro mutagenized yeast genes lacking six-base pair restriction sites | Q28131597 | ||
| In vivo half-life of a protein is a function of its amino-terminal residue | Q28287702 | ||
| A multiubiquitin chain is confined to specific lysine in a targeted short-lived protein | Q29547884 | ||
| Cloning of the Schwanniomyces occidentalis glucoamylase gene (GAM1) and its expression in Saccharomyces cerevisiae | Q33507708 | ||
| Analysis of meiosis-defective mutations in yeast by physical monitoring of recombination. | Q33952129 | ||
| Universality and structure of the N-end rule | Q34430814 | ||
| Expression of the Saccharomyces cerevisiae DNA repair gene RAD6 that encodes a ubiquitin conjugating enzyme, increases in response to DNA damage and in meiosis but remains constant during the mitotic cell cycle | Q35828769 | ||
| Defective presentation to class I-restricted cytotoxic T lymphocytes in vaccinia-infected cells is overcome by enhanced degradation of antigen. | Q36355512 | ||
| Mutations in RAD6, a yeast gene encoding a ubiquitin-conjugating enzyme, stimulate retrotransposition | Q36720521 | ||
| Domain structure and functional analysis of the carboxyl-terminal polyacidic sequence of the RAD6 protein of Saccharomyces cerevisiae | Q36785062 | ||
| Deoxyribonucleic acid repair in the yeast Saccharomyces cerevisiae | Q37054819 | ||
| RAD6 gene of Saccharomyces cerevisiae encodes a protein containing a tract of 13 consecutive aspartates | Q37672743 | ||
| Ubiquitin-conjugating enzymes: novel regulators of eukaryotic cells | Q37936125 | ||
| How are substrates recognized by the ubiquitin-mediated proteolytic system? | Q38767963 | ||
| Ubiquitin-mediated protein degradation. | Q39266643 | ||
| A uniform isopeptide-linked multiubiquitin chain is sufficient to target substrate for degradation in ubiquitin-mediated proteolysis | Q43812538 | ||
| Several mammalian ubiquitin carrier proteins, but not E2(20K), are related to the 20-kDa yeast E2, RAD6. | Q44243062 | ||
| cis-trans recognition and subunit-specific degradation of short-lived proteins | Q44620385 | ||
| The RAD6 protein of Saccharomyces cerevisiae polyubiquitinates histones, and its acidic domain mediates this activity | Q44992776 | ||
| The degradation signal in a short-lived protein | Q45180905 | ||
| Naming a targeting signal | Q68181361 | ||
| Specificity of binding of NH2-terminal residue of proteins to ubiquitin-protein ligase. Use of amino acid derivatives to characterize specific binding sites | Q68268502 | ||
| Post-translational addition of an arginine moiety to acidic NH2 termini of proteins is required for their recognition by ubiquitin-protein ligase | Q68475620 | ||
| The proteasome (multicatalytic protease) is a component of the 1500-kDa proteolytic complex which degrades ubiquitin-conjugated proteins | Q68499670 | ||
| Specificity and frequency of ultraviolet-induced reversion of an iso-1-cytochrome c ochre mutant in radiation-sensitive strains of yeast | Q68687867 | ||
| Affinity purification of ubiquitin-protein ligase on immobilized protein substrates. Evidence for the existence of separate NH2-terminal binding sites on a single enzyme | Q68708773 | ||
| Binding sites of ubiquitin-protein ligase. Binding of ubiquitin-protein conjugates and of ubiquitin-carrier protein | Q69628638 | ||
| Functional heterogeneity of ubiquitin carrier proteins | Q70077950 | ||
| Recombination and mutagenesis in rad6 mutants of Saccharomyces cerevisiae: evidence for multiple functions of the RAD6 gene | Q70221014 | ||
| The isolation, genetics and survival characteristics of ultraviolet light-sensitive mutants in yeast | Q72183420 | ||
| P433 | issue | 16 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | E3 ubiquitin-protein ligase UBR1 YGR184C | Q27547427 |
| E2 ubiquitin-conjugating protein RAD6 YGL058W | Q27547682 | ||
| P304 | page(s) | 7351-5 | |
| P577 | publication date | 1991-08-15 | |
| P1433 | published in | Proceedings of the National Academy of Sciences of the United States of America | Q1146531 |
| P1476 | title | The N-end rule is mediated by the UBC2(RAD6) ubiquitin-conjugating enzyme | |
| P478 | volume | 88 |
| Q33938223 | A chimeric ubiquitin conjugating enzyme that combines the cell cycle properties of CDC34 (UBC3) and the DNA repair properties of RAD6 (UBC2): implications for the structure, function and evolution of the E2s |
| Q36557378 | A conserved RAD6-MDM2 ubiquitin ligase machinery targets histone chaperone ASF1A in tumorigenesis |
| Q27934010 | A conserved RING finger protein required for histone H2B monoubiquitination and cell size control. |
| Q36897180 | A gene encoding a putative tyrosine phosphatase suppresses lethality of an N-end rule-dependent mutant |
| Q28511918 | A mouse amidase specific for N-terminal asparagine. The gene, the enzyme, and their function in the N-end rule pathway |
| Q27936443 | A protein translocation defect linked to ubiquitin conjugation at the endoplasmic reticulum |
| Q40015739 | A ubiquitin mutant with specific defects in DNA repair and multiubiquitination |
| Q38614411 | A ubiquitin-conjugating enzyme is essential for developmental transitions in Dictyostelium |
| Q95808120 | Accumulation of Ade(+) reversions in isoauxotrophic strains ofSaccharomyces cerevisioe allelic inRAD6 during adenine starvation |
| Q74297565 | Alteration in the choice of DNA repair pathway with increasing sequence selective DNA alkylation in the minor groove |
| Q35151521 | Alternative ubiquitin activation/conjugation cascades interact with N-end rule ubiquitin ligases to control degradation of RGS proteins. |
| Q48072395 | An essential role for UBE2A/HR6A in learning and memory and mGLUR-dependent long-term depression |
| Q27937762 | An essential yeast gene encoding a homolog of ubiquitin-activating enzyme |
| Q43251008 | Autophosphorylation-induced degradation of the Pho85 cyclin Pcl5 is essential for response to amino acid limitation |
| Q28594626 | Biochemical and genetic studies of UBR3, a ubiquitin ligase with a function in olfactory and other sensory systems |
| Q27935893 | Bul1, a new protein that binds to the Rsp5 ubiquitin ligase in Saccharomyces cerevisiae |
| Q42562861 | Caffeine-mediated override of checkpoint controls. A requirement for rhp6 (Schizosaccharomyces pombe). |
| Q35908681 | Cdc48p interacts with Ufd3p, a WD repeat protein required for ubiquitin-mediated proteolysis in Saccharomyces cerevisiae. |
| Q44734385 | Characterization of C. elegans RING finger protein 1, a binding partner of ubiquitin-conjugating enzyme 1. |
| Q36169613 | Characterization of HIV-1 integrase N-terminal mutant viruses |
| Q39835408 | Characterization of novel yeast RAD6 (UBC2) ubiquitin-conjugating enzyme mutants constructed by charge-to-alanine scanning mutagenesis |
| Q33285644 | Chromatin signaling to kinetochores: transregulation of Dam1 methylation by histone H2B ubiquitination |
| Q28590671 | Construction and analysis of mouse strains lacking the ubiquitin ligase UBR1 (E3alpha) of the N-end rule pathway |
| Q33725461 | Convergence of Rad6/Rad18 and Fanconi Anemia Tumor Suppressor Pathways upon DNA Damage |
| Q36226144 | Cross-talking histones: implications for the regulation of gene expression and DNA repair |
| Q27748912 | Crystal structure of the Saccharomyces cerevisiae ubiquitin-conjugating enzyme Rad6 at 2.6 A resolution |
| Q34311450 | DNA postreplication repair and mutagenesis in Saccharomyces cerevisiae |
| Q35978862 | DNA postreplication repair modulated by ubiquitination and sumoylation. |
| Q28709604 | DNA repair mechanisms and the bypass of DNA damage in Saccharomyces cerevisiae |
| Q27933435 | DNA2 Encodes a DNA Helicase Essential for Replication of Eukaryotic Chromosomes |
| Q28751734 | Degradation of the Saccharomyces cerevisiae mating-type regulator alpha1: genetic dissection of cis-determinants and trans-acting pathways |
| Q33905811 | Degradation or maintenance: actions of the ubiquitin system on eukaryotic chromatin |
| Q28290146 | Differential regulation of Rad18 through Rad6-dependent mono- and polyubiquitination |
| Q24607508 | Discovery of cellular regulation by protein degradation |
| Q33408783 | Disease-associated mutant ubiquitin causes proteasomal impairment and enhances the toxicity of protein aggregates |
| Q41761925 | Dissection of the functions of the Saccharomyces cerevisiae RAD6 postreplicative repair group in mutagenesis and UV sensitivity |
| Q34280594 | Diversity in genetic in vivo methods for protein-protein interaction studies: from the yeast two-hybrid system to the mammalian split-luciferase system |
| Q36570180 | Domains required for dimerization of yeast Rad6 ubiquitin-conjugating enzyme and Rad18 DNA binding protein |
| Q34684950 | E2 ligase dRad6 regulates DMP53 turnover in Drosophila |
| Q37635419 | E2-C, a cyclin-selective ubiquitin carrier protein required for the destruction of mitotic cyclins |
| Q90736751 | Estrogen Receptors and Ubiquitin Proteasome System: Mutual Regulation |
| Q37044564 | Eukaryotic DNA damage tolerance and translesion synthesis through covalent modifications of PCNA. |
| Q34081429 | Felix Hoppe-Seyler Lecture 2000. The ubiquitin system and the N-end rule pathway |
| Q28485335 | Fission yeast 26S proteasome mutants are multi-drug resistant due to stabilization of the Pap1 transcription factor |
| Q28296085 | Formation and repair of interstrand cross-links in DNA |
| Q73094269 | Genetic interactions between error-prone and error-free postreplication repair pathways in Saccharomyces cerevisiae |
| Q56985312 | HcPT1.2 participates in Pi acquisition in Hebeloma cylindrosporum external hyphae of ectomycorrhizas under high and low phosphate conditions |
| Q46843282 | Heat-inducible degron and the making of conditional mutants |
| Q36747193 | Homologues of wheat ubiquitin-conjugating enzymes--TaUBC1 and TaUBC4 are encoded by small multigene families in Arabidopsis thaliana |
| Q34606562 | Host genes that affect the target-site distribution of the yeast retrotransposon Ty1 |
| Q22010136 | Human Cdc34 and Rad6B ubiquitin-conjugating enzymes target repressors of cyclic AMP-induced transcription for proteolysis |
| Q24313127 | Identification of a family of closely related human ubiquitin conjugating enzymes |
| Q24321129 | Identification of a human ubiquitin-conjugating enzyme that mediates the E6-AP-dependent ubiquitination of p53 |
| Q41531902 | Identification of a portable determinant of cell cycle function within the carboxyl-terminal domain of the yeast CDC34 (UBC3) ubiquitin conjugating (E2) enzyme |
| Q28138234 | Identification of determinants in E2 ubiquitin-conjugating enzymes required for hect E3 ubiquitin-protein ligase interaction |
| Q28709417 | Improved use of a public good selects for the evolution of undifferentiated multicellularity |
| Q41531854 | In vivo function of the proteasome in the ubiquitin pathway |
| Q48060228 | Inactivation of the HR6B ubiquitin-conjugating DNA repair enzyme in mice causes male sterility associated with chromatin modification. |
| Q24323018 | Inhibition of G-protein-mediated MAP kinase activation by a new mammalian gene family |
| Q27939929 | Inhibition of proteolysis and cell cycle progression in a multiubiquitination-deficient yeast mutant |
| Q36555375 | Intragenic suppression among CDC34 (UBC3) mutations defines a class of ubiquitin-conjugating catalytic domains |
| Q36562006 | Involvement of the molecular chaperone Ydj1 in the ubiquitin-dependent degradation of short-lived and abnormal proteins in Saccharomyces cerevisiae |
| Q41112370 | Iodination of tyrosine 59 of ubiquitin selectively blocks ubiquitin's acceptor activity in diubiquitin synthesis catalyzed by E2(25K) |
| Q27938946 | K63 polyubiquitination is a new modulator of the oxidative stress response |
| Q43722249 | Kinetic analysis of the conjugation of ubiquitin to picornavirus 3C proteases catalyzed by the mammalian ubiquitin-protein ligase E3alpha |
| Q27934604 | MMS2, encoding a ubiquitin-conjugating-enzyme-like protein, is a member of the yeast error-free postreplication repair pathway |
| Q46022608 | Methotrexate inhibits proteolysis of dihydrofolate reductase by the N-end rule pathway. |
| Q39498461 | Monoubiquitination is sufficient to signal internalization of the maltose transporter in Saccharomyces cerevisiae |
| Q34276362 | Multiplicity and regulation of genes encoding peptide transporters in Saccharomyces cerevisiae |
| Q57024845 | NF-κB p105 Processing via the Ubiquitin-Proteasome Pathway |
| Q36549697 | Novel CDC34 (UBC3) ubiquitin-conjugating enzyme mutants obtained by charge-to-alanine scanning mutagenesis |
| Q37343840 | Novel inhibitors of Rad6 ubiquitin conjugating enzyme: design, synthesis, identification, and functional characterization |
| Q36163989 | PRT1 of Arabidopsis thaliana encodes a component of the plant N-end rule pathway |
| Q27933838 | Peptides accelerate their uptake by activating a ubiquitin-dependent proteolytic pathway |
| Q39347268 | Phosphorylation by cyclin-dependent kinase-9 controls ubiquitin-conjugating enzyme-2A function |
| Q33576739 | Post-replication repair suppresses duplication-mediated genome instability |
| Q35669902 | Posttranslational modifications of histones by methylation |
| Q40416393 | Proteasomes of the yeast S. cerevisiae: genes, structure and functions |
| Q71980463 | Proteasomes. Complex proteases lead to a new understanding of cellular regulation through proteolysis |
| Q44276071 | Protein interactions within the N-end rule ubiquitin ligation pathway |
| Q29620459 | Protein ubiquitination involving an E1-E2-E3 enzyme ubiquitin thioester cascade |
| Q41064205 | Pub1 acts as an E6-AP-like protein ubiquitiin ligase in the degradation of cdc25. |
| Q81159793 | RAD6 gene is involved in heat shock induction of bleomycin resistance in Saccharomyces cerevisiae |
| Q30388307 | RAD6 promotes homologous recombination repair by activating the autophagy-mediated degradation of heterochromatin protein HP1. |
| Q35665695 | RAD6 regulates the dosage of p53 by a combination of transcriptional and posttranscriptional mechanisms |
| Q24563236 | Rad18 guides poleta to replication stalling sites through physical interaction and PCNA monoubiquitination |
| Q27930655 | Rad6 plays a role in transcriptional activation through ubiquitylation of histone H2B. |
| Q40794267 | Regulated degradation of the transcription factor Gcn4. |
| Q34353641 | Regulation of gross chromosomal rearrangements by ubiquitin and SUMO ligases in Saccharomyces cerevisiae |
| Q24793777 | Regulation of repair by the 26Sproteasome |
| Q33257837 | Replication-dependent and -independent responses of RAD18 to DNA damage in human cells |
| Q34276876 | Requirement of RAD5 and MMS2 for postreplication repair of UV-damaged DNA in Saccharomyces cerevisiae |
| Q34606378 | Role of Saccharomyces cerevisiae chromatin assembly factor-I in repair of ultraviolet radiation damage in vivo |
| Q36160654 | Role of a non-canonical surface of Rad6 in ubiquitin conjugating activity. |
| Q27939180 | Roles of RAD6 epistasis group members in spontaneous polzeta-dependent translesion synthesis in Saccharomyces cerevisiae |
| Q52547316 | Saccharomyces cerevisiae RAD5 influences the excision repair of DNA minor groove adducts. |
| Q27935597 | Selective ubiquitination of calmodulin by UBC4 and a putative ubiquitin protein ligase (E3) from Saccharomyces cerevisiae |
| Q47762708 | Sequence elements that contribute to the degradation of yeast G alpha |
| Q34438710 | Ser(120) of Ubc2/Rad6 regulates ubiquitin-dependent N-end rule targeting by E3{alpha}/Ubr1 |
| Q42077760 | Sit4 phosphatase is functionally linked to the ubiquitin-proteasome system. |
| Q42102982 | Somatic hypermutation of immunoglobulin genes: lessons from proliferating cell nuclear antigenK164R mutant mice. |
| Q28240495 | Subcellular localization and ubiquitin-conjugating enzyme (E2) interactions of mammalian HECT family ubiquitin protein ligases |
| Q36688596 | Synthetic signals for ubiquitin-dependent proteolysis |
| Q38316669 | The 26S proteasome negatively regulates the level of overall genomic nucleotide excision repair |
| Q27934025 | The DNA damage checkpoint response requires histone H2B ubiquitination by Rad6-Bre1 and H3 methylation by Dot1. |
| Q74298282 | The DNA repair protein rad23 is a negative regulator of multi-ubiquitin chain assembly |
| Q36110489 | The Deubiquitinase USP47 Stabilizes MAPK by Counteracting the Function of the N-end Rule ligase POE/UBR4 in Drosophila. |
| Q39406784 | The E2 ubiquitin conjugase Rad6 is required for the ArgR/Mcm1 repression of ARG1 transcription |
| Q34189152 | The N-end rule pathway and regulation by proteolysis |
| Q37947993 | The N-end rule pathway: emerging functions and molecular principles of substrate recognition |
| Q24609395 | The N-end rule: functions, mysteries, uses |
| Q40707410 | The RAD6 gene and protein of Saccharomyces cerevisiae |
| Q27936359 | The RAD6/BRE1 histone modification pathway in Saccharomyces confers radiation resistance through a RAD51-dependent process that is independent of RAD18 |
| Q27935826 | The Saccharomyces cerevisiae RAD6 group is composed of an error-prone and two error-free postreplication repair pathways |
| Q37355959 | The Saccharomyces cerevisiae Rad6 postreplication repair and Siz1/Srs2 homologous recombination-inhibiting pathways process DNA damage that arises in asf1 mutants |
| Q27940309 | The Ubc3 (Cdc34) ubiquitin-conjugating enzyme is ubiquitinated and phosphorylated in vivo |
| Q80597464 | The association between RAD18 Arg302Gln polymorphism and the risk of human non-small-cell lung cancer |
| Q24656114 | The cyclosome, a large complex containing cyclin-selective ubiquitin ligase activity, targets cyclins for destruction at the end of mitosis |
| Q27929822 | The multiubiquitin-chain-binding protein Mcb1 is a component of the 26S proteasome in Saccharomyces cerevisiae and plays a nonessential, substrate-specific role in protein turnover. |
| Q53557506 | The plant homeodomain fingers of fission yeast Msc1 exhibit E3 ubiquitin ligase activity. |
| Q24548218 | The products of the yeast MMS2 and two human homologs (hMMS2 and CROC-1) define a structurally and functionally conserved Ubc-like protein family |
| Q67492448 | The proteasome/multicatalytic-multifunctional proteinase. In vivo function in the ubiquitin-dependent N-end rule pathway of protein degradation in eukaryotes |
| Q34246788 | The ribonucleotide reductase inhibitor, Sml1, is sequentially phosphorylated, ubiquitylated and degraded in response to DNA damage |
| Q43182438 | The ubc-2 gene of Caenorhabditis elegans encodes a ubiquitin-conjugating enzyme involved in selective protein degradation |
| Q44461744 | The ubiquitin proteasome system acutely regulates presynaptic protein turnover and synaptic efficacy |
| Q27860803 | The ubiquitin system |
| Q28587712 | The ubiquitin-conjugating DNA repair enzyme HR6A is a maternal factor essential for early embryonic development in mice |
| Q27934959 | The ubiquitin-conjugating enzyme Rad6 (Ubc2) is required for silencing in Saccharomyces cerevisiae |
| Q33540242 | The ubiquitin-proteasome pathway and pathogenesis of human diseases |
| Q28367002 | The ubiquitin-proteasome pathway and proteasome inhibitors |
| Q36268060 | The ubiquitin-proteasome system of Saccharomyces cerevisiae |
| Q27937937 | The yeast DOA4 gene encodes a deubiquitinating enzyme related to a product of the human tre-2 oncogene |
| Q71843152 | The yeast Rad6 protein: a mediator of homologous recombination across the scaffold attached region at the replication origin ARS1 |
| Q27930877 | Transcriptional regulation by Lge1p requires a function independent of its role in histone H2B ubiquitination |
| Q27935427 | Two RING finger proteins mediate cooperation between ubiquitin-conjugating enzymes in DNA repair. |
| Q40456510 | Ubiquitin and the Enigma of Intracellular Protein Degradation |
| Q33937351 | Ubiquitin as a degradation signal |
| Q34024105 | Ubiquitin ligases of the N-end rule pathway: assessment of mutations in UBR1 that cause the Johanson-Blizzard syndrome |
| Q33723941 | Ubiquitin pathway: another link in the polyubiquitin chain? |
| Q40792160 | Ubiquitin-assisted dissection of protein transport across membranes. |
| Q35971167 | Ubiquitin-dependent degradation of the yeast Mat(alpha)2 repressor enables a switch in developmental state |
| Q27931305 | Ump1p is required for proper maturation of the 20S proteasome and becomes its substrate upon completion of the assembly. |
| Q61552544 | Uracilless death and papillae formation inrad6-1 polyauxotrophic strains ofSaccharomyces cerevisiae |
| Q36052478 | Use of a reporter transgene to generate arabidopsis mutants in ubiquitin-dependent protein degradation |
| Q27936521 | Yeast N-terminal amidase. A new enzyme and component of the N-end rule pathway |
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