YCL047C/POF1 is a novel nicotinamide mononucleotide adenylyltransferase (NMNAT) in Saccharomyces cerevisiae

scientific article

YCL047C/POF1 is a novel nicotinamide mononucleotide adenylyltransferase (NMNAT) in Saccharomyces cerevisiae is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.M114.558643
P932PMC publication ID4140913
P698PubMed publication ID24759102

P2093author name stringMichiko Kato
Su-Ju Lin
P2860cites workMolecular cloning, chromosomal localization, tissue mRNA levels, bacterial expression, and enzymatic properties of human NMN adenylyltransferaseQ24290390
Structure of human NMN adenylyltransferase. A key nuclear enzyme for NAD homeostasisQ27636976
Crystal structure of Haemophilus influenzae NadR protein. A bifunctional enzyme endowed with NMN adenyltransferase and ribosylnicotinimide kinase activitiesQ27639180
Functional characterization of the S. cerevisiae genome by gene deletion and parallel analysisQ27860815
Additional modules for versatile and economical PCR-based gene deletion and modification in Saccharomyces cerevisiaeQ27861085
The malate-aspartate NADH shuttle components are novel metabolic longevity regulators required for calorie restriction-mediated life span extension in yeast.Q27931892
Identification of Isn1 and Sdt1 as glucose- and vitamin-regulated nicotinamide mononucleotide and nicotinic acid mononucleotide [corrected] 5'-nucleotidases responsible for production of nicotinamide riboside and nicotinic acid riboside.Q27932210
Requirement of NAD and SIR2 for life-span extension by calorie restriction in Saccharomyces cerevisiaeQ27933365
Manipulation of a nuclear NAD+ salvage pathway delays aging without altering steady-state NAD+ levelsQ27933382
Secretion of quinolinic acid, an intermediate in the kynurenine pathway, for utilization in NAD+ biosynthesis in the yeast Saccharomyces cerevisiae.Q27933581
The promoter of filamentation (POF1) protein from Saccharomyces cerevisiae is an ATPase involved in the protein quality control processQ27933928
Nicotinamide riboside promotes Sir2 silencing and extends lifespan via Nrk and Urh1/Pnp1/Meu1 pathways to NAD+.Q27934069
Nucleotide degradation and ribose salvage in yeastQ27934673
Discoveries of nicotinamide riboside as a nutrient and conserved NRK genes establish a Preiss-Handler independent route to NAD+ in fungi and humansQ27937147
Phosphate-responsive signaling pathway is a novel component of NAD+ metabolism in Saccharomyces cerevisiaeQ27937830
Identification and characterization of YLR328W, the Saccharomyces cerevisiae structural gene encoding NMN adenylyltransferase. Expression and characterization of the recombinant enzymeQ27938021
Aerobic and anaerobic NAD+ metabolism in Saccharomyces cerevisiaeQ27938512
The NADH diphosphatase encoded by the Saccharomyces cerevisiae NPY1 nudix hydrolase gene is located in peroxisomesQ27940087
Designer deletion strains derived from Saccharomyces cerevisiae S288C: a useful set of strains and plasmids for PCR-mediated gene disruption and other applicationsQ28131600
Inhibition of silencing and accelerated aging by nicotinamide, a putative negative regulator of yeast sir2 and human SIRT1Q28203762
Pyridine nucleotide metabolites stimulate calcium release from sea urchin egg microsomes desensitized to inositol trisphosphateQ28299232
The NAD biosynthesis pathway mediated by nicotinamide phosphoribosyltransferase regulates Sir2 activity in mammalian cellsQ28594408
The Escherichia coli NadR regulator is endowed with nicotinamide mononucleotide adenylyltransferase activityQ28611173
Ribosylnicotinamide kinase domain of NadR protein: identification and implications in NAD biosynthesisQ28611186
Nicotinamide adenine dinucleotide, a metabolic regulator of transcription, longevity and diseaseQ28611191
Biosynthesis of diphosphopyridine nucleotide. II. Enzymatic aspectsQ28646941
Additional modules for versatile and economical PCR-based gene deletion and modification in Saccharomyces cerevisiaeQ29546523
The establishment, inheritance, and function of silenced chromatin in Saccharomyces cerevisiaeQ29614854
Nicotinamide clearance by Pnc1 directly regulates Sir2-mediated silencing and longevityQ30432790
Role of sirtuins in lifespan regulation is linked to methylation of nicotinamideQ30582056
NAD+ metabolite levels as a function of vitamins and calorie restriction: evidence for different mechanisms of longevityQ33533467
Biosynthesis of diphosphopyridine nucleotide. I. Identification of intermediates.Q33969811
Poly(ADP-ribose). The most elaborate metabolite of NAD+.Q33989976
NAD synthase NMNAT acts as a chaperone to protect against neurodegeneration.Q34655913
Quantitation of NAD+ biosynthesis from the salvage pathway in Saccharomyces cerevisiaeQ35538258
Structure and function of nicotinamide mononucleotide adenylyltransferase.Q35743627
The dihydrolipoamide acetyltransferase is a novel metabolic longevity factor and is required for calorie restriction-mediated life span extensionQ36737714
Single sample extraction protocol for the quantification of NAD and NADH redox states in Saccharomyces cerevisiaeQ37092531
CD38 as a regulator of cellular NAD: a novel potential pharmacological target for metabolic conditionsQ37370474
Isolation of NAD cycle mutants defective in nicotinamide mononucleotide deamidase in Salmonella typhimuriumQ39839254
Transcriptional and post-transcriptional control of PHO8 expression by PHO regulatory genes in Saccharomyces cerevisiaeQ40665645
NAD+ salvage pathway proteins suppress proteotoxicity in yeast models of neurodegeneration by promoting the clearance of misfolded/oligomerized proteinsQ40812779
Signaling phosphate starvationQ41211790
Assimilation of endogenous nicotinamide riboside is essential for calorie restriction-mediated life span extension in Saccharomyces cerevisiaeQ41873781
Regulation of NAD synthesis by the trifunctional NadR protein of Salmonella enterica.Q42216077
NAADP: a universal Ca2+ triggerQ42444377
Identification and characterization of a second NMN adenylyltransferase gene in Saccharomyces cerevisiae.Q44322888
Nicotinamide mononucleotide adenylyltransferase. Molecular and enzymatic properties of the homogeneous enzyme from baker's yeast.Q50909068
Assay Methods for Nicotinamide Mononucleotide Adenylyltransferase of Wide ApplicabilityQ58044517
Human equilibrative nucleoside transporter (ENT) family of nucleoside and nucleobase transporter proteinsQ94705295
P433issue22
P407language of work or nameEnglishQ1860
P921main subjectcell biologyQ7141
niacinamideQ192423
Saccharomyces cerevisiaeQ719725
Nicotinamide-nucleotide adenylyltransferase YCL047CQ27549975
P304page(s)15577-87
P577publication date2014-05-30
P1433published inJournal of Biological ChemistryQ867727
P1476titleYCL047C/POF1 is a novel nicotinamide mononucleotide adenylyltransferase (NMNAT) in Saccharomyces cerevisiae
P478volume289

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cites work (P2860)
Q47215863A Functional Link Between NAD+ Homeostasis and N-terminal Protein Acetylation in Saccharomyces cerevisiae.
Q64101935Dual control of NAD synthesis by purine metabolites in yeast
Q97528486Identification and sub-cellular localization of a NAD transporter in Leishmania braziliensis (LbNDT1)
Q37283423Less is more: Nutrient limitation induces cross-talk of nutrient sensing pathways with NAD(+) homeostasis and contributes to longevity
Q53997564Localization and phosphorylation of Plasmodium falciparum nicotinamide/nicotinate mononucleotide adenylyltransferase (PfNMNAT) in intraerythrocytic stages
Q89860291NAD+ Metabolism and Regulation: Lessons From Yeast
Q35891449Nmnat3 Is Dispensable in Mitochondrial NAD Level Maintenance In Vivo
Q35608122Reduced Ssy1-Ptr3-Ssy5 (SPS) signaling extends replicative life span by enhancing NAD+ homeostasis in Saccharomyces cerevisiae
Q34622726Regulation of NAD+ metabolism, signaling and compartmentalization in the yeast Saccharomyces cerevisiae

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