Genome-wide deletion mutant analysis reveals genes required for respiratory growth, mitochondrial genome maintenance and mitochondrial protein synthesis in Saccharomyces cerevisiae

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Genome-wide deletion mutant analysis reveals genes required for respiratory growth, mitochondrial genome maintenance and mitochondrial protein synthesis in Saccharomyces cerevisiae is …
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scholarly articleQ13442814

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P6179Dimensions Publication ID1029158742
P356DOI10.1186/GB-2009-10-9-R95
P932PMC publication ID2768984
P698PubMed publication ID19751518
P5875ResearchGate publication ID26809546

P50authorBenedikt WestermannQ30158841
P2860cites workRecent developments in yeast agingQ21145229
Mitochondrial evolutionQ22065556
Identification and sequence of the gene encoding cytochrome c heme lyase in the yeast Saccharomyces cerevisiaeQ24556388
The fungal vacuole: composition, function, and biogenesisQ24634743
Integrative analysis of the mitochondrial proteome in yeastQ24793149
Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT MethodQ25938999
Global analysis of protein localization in budding yeastQ27653962
The proteome of Saccharomyces cerevisiae mitochondriaQ27653963
Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomicsQ27653964
Functional profiling of the Saccharomyces cerevisiae genomeQ27860544
A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiaeQ27860636
Genome-wide analysis of Rad52 foci reveals diverse mechanisms impacting recombinationQ27929891
A DNA helicase required for maintenance of the functional mitochondrial genome in Saccharomyces cerevisiaeQ27930399
Isolation and inactivation of the nuclear gene encoding the rotenone-insensitive internal NADH: ubiquinone oxidoreductase of mitochondria from Saccharomyces cerevisiaeQ27930947
Characterization of insertion mutations in the Saccharomyces cerevisiae MSH1 and MSH2 genes: evidence for separate mitochondrial and nuclear functionsQ27932283
Genetic basis of mitochondrial function and morphology in Saccharomyces cerevisiaeQ27932416
Recombination-dependent mtDNA partitioning: in vivo role of Mhr1p to promote pairing of homologous DNA.Q27933132
PIF1: a DNA helicase in yeast mitochondriaQ27933153
Cloning and sequencing of the nuclear gene MIP1 encoding the catalytic subunit of the yeast mitochondrial DNA polymerase.Q27933302
Mdm31 and Mdm32 are inner membrane proteins required for maintenance of mitochondrial shape and stability of mitochondrial DNA nucleoids in yeastQ27933308
Mitochondrial DNA maintenance in yeast requires a protein containing a region related to the GTP-binding domain of dynaminQ27934616
Two yeast nuclear genes, CBS1 and CBS2, are required for translation of mitochondrial transcripts bearing the 5'-untranslated COB leaderQ27935129
The Doc1 subunit is a processivity factor for the anaphase-promoting complex.Q27935255
Fzo1p is a mitochondrial outer membrane protein essential for the biogenesis of functional mitochondria in Saccharomyces cerevisiaeQ27935307
Characterization of COX19, a widely distributed gene required for expression of mitochondrial cytochrome oxidaseQ27935578
Pir1p mediates translocation of the yeast Apn1p endonuclease into the mitochondria to maintain genomic stabilityQ27935689
The PET54 gene of Saccharomyces cerevisiae: characterization of a nuclear gene encoding a mitochondrial translational activator and subcellular localization of its product.Q27935696
Mitochondrial protein synthesis is required for maintenance of intact mitochondrial genomes in Saccharomyces cerevisiaeQ27935904
The genetic interactome of prohibitins: coordinated control of cardiolipin and phosphatidylethanolamine by conserved regulators in mitochondriaQ27936543
Functional genomics of genes with small open reading frames (sORFs) in S. cerevisiaeQ27936631
Peripheral mitochondrial inner membrane protein, Mss2p, required for export of the mitochondrially coded Cox2p C tail in Saccharomyces cerevisiaeQ27937026
Assessing systems properties of yeast mitochondria through an interaction map of the organelleQ27937134
The dynamin-related GTPase, Mgm1p, is an intermembrane space protein required for maintenance of fusion competent mitochondriaQ27938333
On the functions of the yeast COX10 and COX11 gene productsQ27938703
Computationally driven, quantitative experiments discover genes required for mitochondrial biogenesisQ27939191
COX16 encodes a novel protein required for the assembly of cytochrome oxidase in Saccharomyces cerevisiaeQ27939371
Aconitase couples metabolic regulation to mitochondrial DNA maintenanceQ27939485
Mgm101p is a novel component of the mitochondrial nucleoid that binds DNA and is required for the repair of oxidatively damaged mitochondrial DNAQ27939716
Genetic and structural analysis of Hmg2p-induced endoplasmic reticulum remodeling in Saccharomyces cerevisiaeQ27939773
The role of DNA double-strand breaks in spontaneous homologous recombination in S. cerevisiaeQ27940078
Disruption and basic phenotypic analysis of 18 novel genes from the yeast Saccharomyces cerevisiaeQ27940102
Mitochondrial fusion in yeast requires the transmembrane GTPase Fzo1pQ27940327
Feasting, fasting and fermenting. Glucose sensing in yeast and other cellsQ27940330
Designer deletion strains derived from Saccharomyces cerevisiae S288C: a useful set of strains and plasmids for PCR-mediated gene disruption and other applicationsQ28131600
Getting started with yeastQ28131602
Computational method to predict mitochondrially imported proteins and their targeting sequencesQ29547581
Mitochondria, oxidants, and agingQ29547594
Systematic screen for human disease genes in yeastQ29617873
Yeast carbon catabolite repressionQ29622932
Primary structure and import pathway of the rotenone-insensitive NADH-ubiquinone oxidoreductase of mitochondria from Saccharomyces cerevisiaeQ30360394
ATP13, a nuclear gene ofSaccharomyces cerevisiaeessential for the expression of subunit 9 of the mitochondrialATPaseQ33318200
Maintenance and integrity of the mitochondrial genome: a plethora of nuclear genes in the budding yeastQ33334641
Oxidative phosphorylation at the fin de siècleQ33538525
Disruption of the yeast nuclear PET54 gene blocks excision of mitochondrial intron aI5 beta from pre-mRNA for cytochrome c oxidase subunit I.Q33610094
Mitochondrial assembly in yeast.Q33665594
Cells have distinct mechanisms to maintain protection against different reactive oxygen species: oxidative-stress-response genesQ33695799
COX10 codes for a protein homologous to the ORF1 product of Paracoccus denitrificans and is required for the synthesis of yeast cytochrome oxidaseQ33932529
How did Saccharomyces evolve to become a good brewer?Q33993786
Identification of the gene encoding lipoate-protein ligase A of Escherichia coli. Molecular cloning and characterization of the lplA gene and gene productQ34060812
Genetic approaches to the study of mitochondrial biogenesis in yeastQ35534771
Aberrant translation of cytochrome c oxidase subunit 1 mRNA species in the absence of Mss51p in the yeast Saccharomyces cerevisiaeQ35613363
Regulation of mitochondrial translation in yeastQ36338048
The where, when, and how of organelle acidification by the yeast vacuolar H+-ATPaseQ36416690
Product of Saccharomyces cerevisiae nuclear gene PET494 activates translation of a specific mitochondrial mRNA.Q36898661
Molecular machinery of mitochondrial dynamics in yeastQ36909235
Intersection of RNA processing and the type II fatty acid synthesis pathway in yeast mitochondriaQ36949735
The long physiological reach of the yeast vacuolar H+-ATPaseQ37000446
PET genes of Saccharomyces cerevisiaeQ37056313
Mss51p promotes mitochondrial Cox1p synthesis and interacts with newly synthesized Cox1p.Q37368127
VMA8 encodes a 32-kDa V1 subunit of the Saccharomyces cerevisiae vacuolar H(+)-ATPase required for function and assembly of the enzyme complexQ42686936
Oxygen stress: a regulator of apoptosis in yeastQ42797452
Coq3 and Coq4 define a polypeptide complex in yeast mitochondria for the biosynthesis of coenzyme Q.Q46201484
Cloning of a nuclear gene MRS1 involved in the excision of a single group I intron (bI3) from the mitochondrial COB transcript in S. cerevisiaeQ46661542
Mechanism of selectivity of an angiogenesis inhibitor from screening a genome-wide set of Saccharomyces cerevisiae deletion strains.Q46761627
Saccharomyces Genome DatabaseQ46791139
Selective and non-selective autophagic degradation of mitochondria in yeastQ48408669
The role of subunit 4, a nuclear-encoded protein of the F0 sector of yeast mitochondrial ATP synthase, in the assembly of the whole complex.Q52486307
Systematic screening of nuclear encoded proteins involved in the splicing metabolism of group II introns in yeast mitochondria.Q52938427
A “Petite Obligate” Mutant ofSaccharomyces cerevisiaeQ57246534
Analysis of mitochondrial translation products in Vivo and in organello in yeastQ63359604
Loss of vacuolar proton-translocating ATPase activity in yeast results in chronic oxidative stressQ79534685
P433issue9
P407language of work or nameEnglishQ1860
P921main subjectmitochondrionQ39572
Saccharomyces cerevisiaeQ719725
Rrg8p YPR116WQ27549160
Ccm1p YGR150CQ27550427
Rrg9p YNL213CQ27550899
Rrg1p YDR065WQ27551562
Gep5p YLR091WQ27551587
P304page(s)R95
P577publication date2009-01-01
P1433published inGenome BiologyQ5533480
P1476titleGenome-wide deletion mutant analysis reveals genes required for respiratory growth, mitochondrial genome maintenance and mitochondrial protein synthesis in Saccharomyces cerevisiae
P478volume10

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cites work (P2860)
Q36499256A Signaling Lipid Associated with Alzheimer's Disease Promotes Mitochondrial Dysfunction
Q33826387A novel bZIP protein, Gsb1, is required for oxidative stress response, mating, and virulence in the human pathogen Cryptococcus neoformans
Q36776353A unique ecological niche fosters hybridization of oak-tree and vineyard isolates of Saccharomyces cerevisiae
Q35585529ATG18 and FAB1 are involved in dehydration stress tolerance in Saccharomyces cerevisiae
Q27939270Activation of 5'-3' exoribonuclease Xrn1 by cofactor Dcs1 is essential for mitochondrial function in yeast
Q38078949Amyloids and yeast prion biology
Q42144725Analysis of Protein-protein Interaction Interface between Yeast Mitochondrial Proteins Rim1 and Pif1 Using Chemical Cross-linking Mass Spectrometry.
Q40119894Bacterial Signaling Nucleotides Inhibit Yeast Cell Growth by Impacting Mitochondrial and Other Specifically Eukaryotic Functions.
Q42030829Building a new bridge between metabolism, free radicals and longevity
Q38757601Cancer-associated isocitrate dehydrogenase mutations induce mitochondrial DNA instability
Q90172695Ccm1p is a 15S rRNA primary transcript processing factor as elucidated by a novel in vivo system in Saccharomyces cerevisiae
Q30657240Cell periphery-related proteins as major genomic targets behind the adaptive evolution of an industrial Saccharomyces cerevisiae strain to combined heat and hydrolysate stress
Q96302584Cell size sets the diameter of the budding yeast contractile ring
Q27936564Coa3 and Cox14 are essential for negative feedback regulation of COX1 translation in mitochondria
Q36395398Comparative functional genomic screens of three yeast deletion collections reveal unexpected effects of genotype in response to diverse stress
Q35652759Comprehensive survey of condition-specific reproductive isolation reveals genetic incompatibility in yeast
Q27934526Cox25 Teams Up with Mss51, Ssc1, and Cox14 to Regulate Mitochondrial Cytochrome c Oxidase Subunit 1 Expression and Assembly in Saccharomyces cerevisiae
Q27938800DMR1 (CCM1/YGR150C) of Saccharomyces cerevisiae encodes an RNA-binding protein from the pentatricopeptide repeat family required for the maintenance of the mitochondrial 15S ribosomal RNA.
Q34129957Defects in mitochondrial fatty acid synthesis result in failure of multiple aspects of mitochondrial biogenesis in Saccharomyces cerevisiae.
Q35604289Distinct functions of evolutionary conserved MSF1 and late embryogenesis abundant (LEA)-like domains in mitochondria
Q36926606Effects of Fcj1-Mos1 and mitochondrial division on aggregation of mitochondrial DNA nucleoids and organelle morphology
Q52367409Efficient termination of nuclear lncRNA transcription promotes mitochondrial genome maintenance.
Q47675174Elimination of the last reactions in ergosterol biosynthesis alters the resistance of Saccharomyces cerevisiae to multiple stresses
Q36676640Elongator-dependent modification of cytoplasmic tRNALysUUU is required for mitochondrial function under stress conditions
Q38370208End-of-life cell cycle arrest contributes to stochasticity of yeast replicative aging
Q28818584Functional and regulatory profiling of energy metabolism in fission yeast
Q28264035Genetic instability in budding and fission yeast-sources and mechanisms
Q42355621Genome-wide analysis of intracellular pH reveals quantitative control of cell division rate by pH(c) in Saccharomyces cerevisiae
Q88697987Hermes Transposon Mutagenesis Shows [URE3] Prion Pathology Prevented by a Ubiquitin-Targeting Protein: Evidence for Carbon/Nitrogen Assimilation Cross Talk and a Second Function for Ure2p in Saccharomyces cerevisiae
Q35105750High-resolution profiling of stationary-phase survival reveals yeast longevity factors and their genetic interactions.
Q42953233Identification of gold nanoparticle-resistant mutants of Saccharomyces cerevisiae suggests a role for respiratory metabolism in mediating toxicity.
Q42098919Identification of novel causative genes determining the complex trait of high ethanol tolerance in yeast using pooled-segregant whole-genome sequence analysis.
Q28590744Identifying genes required for respiratory growth of fission yeast
Q42431012In vivo phosphorylation of Ser21 and Ser83 during nutrient-induced activation of the yeast protein kinase A (PKA) target trehalase
Q27935659Inaccurately assembled cytochrome c oxidase can lead to oxidative stress-induced growth arrest.
Q47718370Investigation of Candida parapsilosis virulence regulatory factors during host-pathogen interaction.
Q52861844Isolation of conditional mutations in genes essential for viability of Cryptococcus neoformans.
Q33629464Loss of the SIN3 transcriptional corepressor results in aberrant mitochondrial function
Q27933561Mdm36 is a mitochondrial fission-promoting protein in Saccharomyces cerevisiae
Q38376620Mechanisms by which different functional states of mitochondria define yeast longevity
Q41878294MitoLoc: A method for the simultaneous quantification of mitochondrial network morphology and membrane potential in single cells
Q37934279Mitochondria and fungal pathogenesis: drug tolerance, virulence, and potential for antifungal therapy.
Q39241538Mitochondria-organelle contact sites: the plot thickens.
Q37936567Mitochondrial dynamics in yeast cell death and aging
Q28299119Mitochondrial fusion and fission in cell life and death
Q37795348Mitochondrial inheritance in fungi
Q26829426Mitochondrial inheritance in yeast
Q35867270Mitochondrial sorting and assembly machinery subunit Sam37 in Candida albicans: insight into the roles of mitochondria in fitness, cell wall integrity, and virulence
Q48033276Natural antisense transcripts are linked to the modulation of mitochondrial function and teliospore dormancy in Ustilago maydis.
Q42740351Neurotoxic 43-kDa TAR DNA-binding protein (TDP-43) triggers mitochondrion-dependent programmed cell death in yeast
Q92875175Non-canonical translation initiation in yeast generates a cryptic pool of mitochondrial proteins
Q28068151Nonconventional localizations of cytosolic aminoacyl-tRNA synthetases in yeast and human cells
Q24298785Nuclear envelope phosphatase 1-regulatory subunit 1 (formerly TMEM188) is the metazoan Spo7p ortholog and functions in the lipin activation pathway
Q47805637On the origins and industrial applications of Saccharomyces cerevisiae × Saccharomyces kudriavzevii hybrids
Q36198245Parallel genetic changes and nonparallel gene-environment interactions characterize the evolution of drug resistance in yeast
Q57039833Pathogenic variants in glutamyl-tRNA amidotransferase subunits cause a lethal mitochondrial cardiomyopathy disorder
Q27930262Phosphatidylethanolamine biosynthesis in mitochondria: phosphatidylserine (PS) trafficking is independent of a PS decarboxylase and intermembrane space proteins UPS1P and UPS2P.
Q27005796Power(2): the power of yeast genetics applied to the powerhouse of the cell
Q89533150Quantitative global studies reveal differential translational control by start codon context across the fungal kingdom
Q51764746Rapid Nuclear Exclusion of Hcm1 in Aging Saccharomyces cerevisiae Leads to Vacuolar Alkalization and Replicative Senescence.
Q42491997Real-time monitoring of basal H2O2 levels with peroxiredoxin-based probes.
Q47423991Specialized ribosomes and specific ribosomal protein paralogs control translation of mitochondrial proteins
Q41783250Specific changes in mitochondrial lipidome alter mitochondrial proteome and increase the geroprotective efficiency of lithocholic acid in chronologically aging yeast
Q99239624Systematic analysis of nuclear gene function in respiratory growth and expression of the mitochondrial genome in S. cerevisiae
Q40142084The Arabidopsis COX11 Homolog is Essential for Cytochrome c Oxidase Activity
Q42198697The Genetic Requirements for Pentose Fermentation in Budding Yeast
Q35636822The Heme Transport Capacity of LHR1 Determines the Extent of Virulence in Leishmania amazonensis.
Q27938851The MEF2 gene is essential for yeast longevity, with a dual role in cell respiration and maintenance of mitochondrial membrane potential
Q58324417The Sec1/Munc18 (SM) protein Vps45 is involved in iron uptake, mitochondrial function and virulence in the pathogenic fungus Cryptococcus neoformans
Q26749118The crucial impact of lysosomes in aging and longevity
Q53643796The impact of medium acidity on the chronological life span of Saccharomyces cerevisiae - lipids, signaling cascades, mitochondrial and vacuolar functions.
Q33947203The nutrient stress-induced small GTPase Rab5 contributes to the activation of vesicle trafficking and vacuolar activity
Q35152954The role of mitochondrial DNA mutation on neurodegenerative diseases
Q33779511The yeast deletion collection: a decade of functional genomics
Q36399070The yeast protein kinase Sch9 adjusts V-ATPase assembly/disassembly to control pH homeostasis and longevity in response to glucose availability
Q35684922Vacuolar ATPase depletion affects mitochondrial ATPase function, kinetoplast dependency, and drug sensitivity in trypanosomes
Q28818537Widespread Genetic Incompatibilities between First-Step Mutations during Parallel Adaptation of Saccharomyces cerevisiae to a Common Environment
Q37608523Yeast cells expressing the human mitochondrial DNA polymerase reveal correlations between polymerase fidelity and human disease progression
Q33832860mip1 containing mutations associated with mitochondrial disease causes mutagenesis and depletion of mtDNA in Saccharomyces cerevisiae

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