Genetic analysis and enzyme activity suggest the existence of more than one minimal functional unit capable of synthesizing phosphoribosyl pyrophosphate in Saccharomyces cerevisiae

scientific article

Genetic analysis and enzyme activity suggest the existence of more than one minimal functional unit capable of synthesizing phosphoribosyl pyrophosphate in Saccharomyces cerevisiae is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1074/JBC.274.18.12480
P698PubMed publication ID10212224

P2093author name stringB Hove-Jensen
M Schweizer
Y Hernando
A Parr
A T Carter
P2860cites workThe Minimal Gene Complement of Mycoplasma genitaliumQ22065573
Molecular cloning and sequencing of human cDNA for phosphoribosyl pyrophosphate synthetase subunit IIQ24306536
Cloning and sequencing of human complementary DNA for the phosphoribosylpyrophosphate synthetase-associated protein 39Q24328754
Molecular cloning of a human cDNA for the 41-kDa phosphoribosylpyrophosphate synthetase-associated proteinQ24329085
A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye bindingQ25938984
Studies on transformation of Escherichia coli with plasmidsQ27860598
Whole-genome random sequencing and assembly of Haemophilus influenzae RdQ27860765
A novel genetic system to detect protein-protein interactionsQ27860915
Saccharomyces cerevisiae contains four fatty acid activation (FAA) genes: an assessment of their role in regulating protein N-myristoylation and cellular lipid metabolismQ27935563
Comparison of the Reactivity of Tetradecenoic Acids, a Triacsin, and Unsaturated Oximes with Four Purified Saccharomyces cerevisiae Fatty Acid Activation ProteinsQ27938103
Molecular evolution of the HSP70 multigene familyQ27940113
New heterologous modules for classical or PCR-based gene disruptions in Saccharomyces cerevisiaeQ28131599
A positive selection for mutants lacking orotidine-5'-phosphate decarboxylase activity in yeast: 5-fluoro-orotic acid resistanceQ28131606
A new efficient gene disruption cassette for repeated use in budding yeastQ28131647
Rat liver phosphoribosyl pyrophosphate synthetase: existence of the purified enzyme as heterogeneous aggregates and identification of the catalytic subunitQ28564772
Kinetic and regulatory properties of rat liver phosphoribosylpyrophosphate synthetase complex are partly distinct from those of isolated recombinant component catalytic subunitsQ28583438
Organellar and cytosolic localization of four phosphoribosyl diphosphate synthase isozymes in spinachQ31912910
Mammalian phosphoribosyl-pyrophosphate synthetaseQ34296530
Structure of the gene encoding phosphoribosylpyrophosphate synthetase (prsA) in Salmonella typhimuriumQ36208658
Molecular characterization of phosphoribosylpyrophosphate synthetase from Leishmania donovaniQ36771516
Identification of tms-26 as an allele of the gcaD gene, which encodes N-acetylglucosamine 1-phosphate uridyltransferase in Bacillus subtilisQ39939478
Mutation in the phosphoribosylpyrophosphate synthetase gene (prs) that results in simultaneous requirements for purine and pyrimidine nucleosides, nicotinamide nucleotide, histidine, and tryptophan in Escherichia coliQ39952316
Construction of an improved host strain for two hybrid screeningQ40399452
Cloning of two distinct copies of human phosphoribosylpyrophosphate synthetase cDNA.Q40513667
Complete cDNA sequence of rat phosphoribosylpyrophosphate synthetase subunit II (PRS II).Q40538726
Complete cDNA sequence of rat phosphoribosylpyrophosphate synthetase subunit I (PRS I).Q40538731
Primary structure of the tms and prs genes of Bacillus subtilisQ42642441
The stringent response in Streptomyces coelicolor A3(2)Q43580459
A family of yeast expression vectors containing the phage f1 intergenic regionQ45019834
Cloning and sequencing of rat cDNA for the 41-kDa phosphoribosylpyrophosphate synthetase-associated protein has a high homology to the catalytic subunits and the 39-kDa associated proteinQ48055152
Phosphoribosylpyrophosphate synthetase (PRS): a new gene family in Saccharomyces cerevisiaeQ48080408
A cyanobacterial gene encoding a protein with extensive homology to mammalian phosphoribosylpyrophosphate synthetaseQ48095949
Conformation of MgATP Bound to 5-phospho-alpha-d-ribose 1-diphosphate Synthetase by Two-dimensional Transferred Nuclear Overhauser Effect SpectroscopyQ50143541
PRS1 is a key member of the gene family encoding phosphoribosylpyrophosphate synthetase in Saccharomyces cerevisiae.Q52524891
Three ATP1 genes are present on chromosome II in Saccharomyces cerevisiaeQ71216767
Overexpression of Bacillus subtilis phosphoribosylpyrophosphate synthetase and crystallization and preliminary X-ray characterization of the free enzyme and its substrate-effector complexesQ71565971
Polyprenylphosphate-pentoses in mycobacteria are synthesized from 5-phosphoribose pyrophosphateQ71824939
Purification and Characterization of Phosphoribosylpyrophosphate Synthetase from Rubber Tree LatexQ74770845
P433issue18
P407language of work or nameEnglishQ1860
P921main subjectSaccharomyces cerevisiaeQ719725
Ribose phosphate diphosphokinase subunit PRS1 YKL181WQ27547286
Ribose phosphate diphosphokinase subunit PRS2 YER099CQ27550279
Ribose phosphate diphosphokinase subunit PRS5 YOL061WQ27550864
Ribose phosphate diphosphokinase subunit PRS4 YBL068WQ27552260
Ribose phosphate diphosphokinase subunit PRS3 YHL011CQ27552985
P304page(s)12480-7
P577publication date1999-04-30
P1433published inJournal of Biological ChemistryQ867727
P1476titleGenetic analysis and enzyme activity suggest the existence of more than one minimal functional unit capable of synthesizing phosphoribosyl pyrophosphate in Saccharomyces cerevisiae
P478volume274

Reverse relations

cites work (P2860)
Q37856366A brief history of TOR.
Q93098997A quantitative screen for metabolic enzyme structures reveals patterns of assembly across the yeast metabolic network
Q39502145Characterization of the promoter of PRS1 in Saccharomyces cerevisiae identifies three regions potentially involved in control of expression.
Q41388895Differential proteome-metabolome profiling of YCA1-knock-out and wild type cells reveals novel metabolic pathways and cellular processes dependent on the yeast metacaspase
Q27936927Heterooligomeric phosphoribosyl diphosphate synthase of Saccharomyces cerevisiae: combinatorial expression of the five PRS genes in Escherichia coli
Q33624188Identification of a Ribose-Phosphate Pyrophosphokinase that Can Interact In Vivo with the Anaphase Promoting Complex/Cyclosome
Q33781701Improving the iMM904 S. cerevisiae metabolic model using essentiality and synthetic lethality data
Q51390566Metabolic gene products have evolved to interact with the cell wall integrity pathway in Saccharomyces cerevisiae.
Q30396867Phosphoribosyl Diphosphate (PRPP): Biosynthesis, Enzymology, Utilization, and Metabolic Significance.
Q41818534Phosphoribosyl pyrophosphate synthetase activity affects growth and riboflavin production in Ashbya gossypii
Q52330940Signature pathway expression of xylose utilization in the genetically engineered industrial yeast Saccharomyces cerevisiae.
Q28469306Structure-templated predictions of novel protein interactions from sequence information
Q29614487Transcriptional profiling shows that Gcn4p is a master regulator of gene expression during amino acid starvation in yeast

Search more.