Nucleolin/Nsr1p binds to the 3' noncoding region of the tombusvirus RNA and inhibits replication.

scientific article

Nucleolin/Nsr1p binds to the 3' noncoding region of the tombusvirus RNA and inhibits replication. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.VIROL.2009.10.007
P932PMC publication ID2788044
P698PubMed publication ID19861225
P5875ResearchGate publication ID38040436

P50authorZhenghe LiQ40101271
P2093author name stringPeter D Nagy
Yi Jiang
P2860cites workThe p92 polymerase coding region contains an internal RNA element required at an early step in Tombusvirus genome replicationQ24520614
An internally located RNA hairpin enhances replication of Tomato bushy stunt virus RNAsQ24540527
A Functional Genomic Screen Identifies Cellular Cofactors of Hepatitis C Virus ReplicationQ27489843
Recognition of pre-formed and flexible elements of an RNA stem-loop by nucleolinQ27632444
Nucleolin: a multifunctional major nucleolar phosphoproteinQ28295172
Mouse nucleolin binds to 4.5S RNAh, a small noncoding RNAQ28508658
RNA interference screen for human genes associated with West Nile virus infectionQ29616376
Drosophila RNAi screen identifies host genes important for influenza virus replicationQ30370530
Yeast genome-wide screen reveals dissimilar sets of host genes affecting replication of RNA virusesQ30851910
Genome-wide screen identifies host genes affecting viral RNA recombinationQ33219824
Screening of the yeast yTHC collection identifies essential host factors affecting tombusvirus RNA recombinationQ33231719
Influenza A virus non-structural protein 1 (NS1) interacts with cellular multifunctional protein nucleolin during infectionQ33296558
Sugar-inducible expression of the nucleolin-1 gene of Arabidopsis thaliana and its role in ribosome synthesis, growth and developmentQ33343711
A key role for heat shock protein 70 in the localization and insertion of tombusvirus replication proteins to intracellular membranesQ33400948
Viral ribonucleoprotein complex formation and nucleolar-cytoplasmic relocalization of nucleolin in poliovirus-infected cellsQ33783606
The carboxy-terminal fragment of nucleolin interacts with the nucleocapsid domain of retroviral gag proteins and inhibits virion assembly.Q33826575
Genome-wide RNAi screen reveals a specific sensitivity of IRES-containing RNA viruses to host translation inhibitionQ33848936
Suppression of viral RNA recombination by a host exoribonucleaseQ34434892
Systematic, genome-wide identification of host genes affecting replication of a positive-strand RNA virusQ34791544
Characterization of AtNUC-L1 reveals a central role of nucleolin in nucleolus organization and silencing of AtNUC-L2 gene in ArabidopsisQ35613446
Formation of a complex between nucleolin and replication protein A after cell stress prevents initiation of DNA replicationQ36327063
Yeast as a model host to dissect functions of viral and host factors in tombusvirus replicationQ36346850
Nucleolin: a multiFACeTed protein.Q36678131
Cdc34p ubiquitin-conjugating enzyme is a component of the tombusvirus replicase complex and ubiquitinates p33 replication proteinQ36747704
In vitro assembly of the Tomato bushy stunt virus replicase requires the host Heat shock protein 70Q37018802
Yeast as a model host to explore plant virus-host interactionsQ37142027
Translation elongation factor 1A is a component of the tombusvirus replicase complex and affects the stability of the p33 replication co-factor.Q37447365
The host Pex19p plays a role in peroxisomal localization of tombusvirus replication proteinsQ38288494
Authentic replication and recombination of Tomato bushy stunt virus RNA in a cell-free extract from yeastQ38609912
The RNA replication enhancer element of tombusviruses contains two interchangeable hairpins that are functional during plus-strand synthesisQ39698369
Characterization of the RNA-binding domains in the replicase proteins of tomato bushy stunt virusQ39864035
Nonhomologous RNA recombination in tombusviruses: generation and evolution of defective interfering RNAs by stepwise deletionsQ40037688
Purification of the cucumber necrosis virus replicase from yeast cells: role of coexpressed viral RNA in stimulation of replicase activityQ40496402
Virus-induced gene silencing in tomatoQ40634919
Role of an internal and two 3'-terminal RNA elements in assembly of tombusvirus replicaseQ42582007
Specific binding of tombusvirus replication protein p33 to an internal replication element in the viral RNA is essential for replicationQ42709852
Identification of essential host factors affecting tombusvirus RNA replication based on the yeast Tet promoters Hughes CollectionQ43155068
Proteomics analysis of the tombusvirus replicase: Hsp70 molecular chaperone is associated with the replicase and enhances viral RNA replicationQ43236251
Host transcription factor Rpb11p affects tombusvirus replication and recombination via regulating the accumulation of viral replication proteinsQ44444083
The conserved N-terminal domain of herpes simplex virus 1 UL24 protein is sufficient to induce the spatial redistribution of nucleolin.Q45395758
Tomato bushy stunt virus co-opts the RNA-binding function of a host metabolic enzyme for viral genomic RNA synthesisQ45396593
Functional interaction of hepatitis C Virus NS5B with Nucleolin GAR domainQ45402949
Kinetics and functional studies on interaction between the replicase proteins of Tomato Bushy Stunt Virus: requirement of p33:p92 interaction for replicase assemblyQ45423151
Nucleolin and the packaging signal, psi, promote the budding of human immunodeficiency virus type-1 (HIV-1).Q45673844
Yeast as a model host to study replication and recombination of defective interfering RNA of Tomato bushy stunt virusQ45711001
pGD vectors: versatile tools for the expression of green and red fluorescent protein fusions in agroinfiltrated plant leavesQ46640398
Silencing of Nicotiana benthamiana Xrn4p exoribonuclease promotes tombusvirus RNA accumulation and recombination.Q51809357
A functional genetic assay for nuclear trafficking in plantsQ57080626
Expression of the Arabidopsis Xrn4p 5'-3' exoribonuclease facilitates degradation of tombusvirus RNA and promotes rapid emergence of viral variants in plants.Q64892986
Light differentially regulates cell division and the mRNA abundance of pea nucleolin during de-etiolationQ73388060
Nucleolin stimulates viral internal ribosome entry site-mediated translationQ73934938
Exploiting alternative subcellular location for replication: tombusvirus replication switches to the endoplasmic reticulum in the absence of peroxisomesQ79755909
The role of the p33:p33/p92 interaction domain in RNA replication and intracellular localization of p33 and p92 proteins of Cucumber necrosis tombusvirusQ81814264
P4510describes a project that usesImageQuantQ112270642
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectNsr1p YGR159CQ27548071
P304page(s)10-20
P577publication date2009-10-27
P1433published inVirologyQ7934867
P1476titleNucleolin/Nsr1p binds to the 3' noncoding region of the tombusvirus RNA and inhibits replication
P478volume396

Reverse relations

cites work (P2860)
Q45359585An inhibitory function of WW domain-containing host proteins in RNA virus replication
Q41169421Authentic in vitro replication of two tombusviruses in isolated mitochondrial and endoplasmic reticulum membranes
Q39802752Coilin, the signature protein of Cajal bodies, differentially modulates the interactions of plants with viruses in widely different taxa
Q37336768Cyclophilin A binds to the viral RNA and replication proteins, resulting in inhibition of tombusviral replicase assembly
Q35592223Diverse roles of host RNA binding proteins in RNA virus replication
Q38354315Functions of the 5' and 3' ends of calicivirus genomes
Q43411505Garlic virus X 11-kDa protein granules move within the cytoplasm and traffic a host protein normally found in the nucleolus
Q37801998Global Genomics and Proteomics Approaches to Identify Host Factors as Targets to Induce Resistance Against Tomato Bushy Stunt Virus
Q41843369Identification of novel host factors via conserved domain search: Cns1 cochaperone is a novel restriction factor of tombusvirus replication in yeast
Q37800653Involvement of the plant nucleolus in virus and viroid infections: parallels with animal pathosystems.
Q44996866Nucleocapsid protein VP15 of White spot syndrome virus colocalizes with the nucleolar proteins nucleolin and fibrillarin
Q37336680Nucleolin interacts with the dengue virus capsid protein and plays a role in formation of infectious virus particles
Q39523218Nucleolin interacts with the feline calicivirus 3' untranslated region and the protease-polymerase NS6 and NS7 proteins, playing a role in virus replication
Q58590736Nucleolin mediates the internalization of rabbit hemorrhagic disease virus through clathrin-dependent endocytosis
Q34045720Nucleolin promotes in vitro translation of feline calicivirus genomic RNA.
Q41844933Proteome-wide overexpression of host proteins for identification of factors affecting tombusvirus RNA replication: an inhibitory role of protein kinase C.
Q34162254The TPR domain in the host Cyp40-like cyclophilin binds to the viral replication protein and inhibits the assembly of the tombusviral replicase
Q35151994The expanding functions of cellular helicases: the tombusvirus RNA replication enhancer co-opts the plant eIF4AIII-like AtRH2 and the DDX5-like AtRH5 DEAD-box RNA helicases to promote viral asymmetric RNA replication
Q37098244The glutathione transferase of Nicotiana benthamiana NbGSTU4 plays a role in regulating the early replication of Bamboo mosaic virus
Q34059324The hop-like stress-induced protein 1 cochaperone is a novel cell-intrinsic restriction factor for mitochondrial tombusvirus replication.
Q38243326Tombusvirus-yeast interactions identify conserved cell-intrinsic viral restriction factors
Q38174760Viruses and the nucleolus: the fatal attraction.

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