scholarly article | Q13442814 |
P50 | author | Rainer J. Klement | Q56073415 |
P2093 | author name string | M K Fink | |
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The ketogenic diet is an effective adjuvant to radiation therapy for the treatment of malignant glioma | Q28730187 | ||
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Hepatic fibroblast growth factor 21 is regulated by PPARalpha and is a key mediator of hepatic lipid metabolism in ketotic states | Q29615208 | ||
MAP kinase signalling pathways in cancer | Q29615542 | ||
THE METABOLISM OF TUMORS IN THE BODY | Q29616202 | ||
Elevated glucose and diabetes promote interleukin-12 cytokine gene expression in mouse macrophages | Q30439419 | ||
Tumor growth in patients with tuberous sclerosis complex on the ketogenic diet | Q33445828 | ||
Metabolic management of glioblastoma multiforme using standard therapy together with a restricted ketogenic diet: Case Report | Q33562229 | ||
Is Akt the "Warburg kinase"?-Akt-energy metabolism interactions and oncogenesis | Q33623036 | ||
Fasting and cancer treatment in humans: A case series report. | Q33627959 | ||
Weight change therapy as a potential treatment for end-stage ovarian carcinoma. | Q33629673 | ||
Influence of a ketogenic diet, fish-oil, and calorie restriction on plasma metabolites and lipids in C57BL/6J mice. | Q33718016 | ||
Reduced levels of IGF-I mediate differential protection of normal and cancer cells in response to fasting and improve chemotherapeutic index | Q33718131 | ||
ERGO: a pilot study of ketogenic diet in recurrent glioblastoma | Q33778107 | ||
Plant-animal subsistence ratios and macronutrient energy estimations in worldwide hunter-gatherer diets | Q33843807 | ||
Insulin receptor isoform A, a newly recognized, high-affinity insulin-like growth factor II receptor in fetal and cancer cells. | Q33858986 | ||
Insulin, chemotherapy, and the mechanisms of malignancy: the design and the demise of cancer | Q33918810 | ||
Caloric restriction and the aging process: a critique | Q33954183 | ||
Differential utilization of ketone bodies by neurons and glioma cell lines: a rationale for ketogenic diet as experimental glioma therapy | Q33972116 | ||
Roles of caloric restriction, ketogenic diet and intermittent fasting during initiation, progression and metastasis of cancer in animal models: a systematic review and meta-analysis | Q34042713 | ||
The ketogenic diet reverses gene expression patterns and reduces reactive oxygen species levels when used as an adjuvant therapy for glioma | Q34174680 | ||
Reversal of type 2 diabetes: normalisation of beta cell function in association with decreased pancreas and liver triacylglycerol. | Q34191173 | ||
Metabolic reprogramming induced by ketone bodies diminishes pancreatic cancer cachexia | Q34193811 | ||
Akt and phospholipase Cγ are involved in the regulation of growth and migration of MDA-MB-468 breast cancer and SW480 colon cancer cells when cultured with diabetogenic levels of glucose and insulin | Q34255016 | ||
Metabolic modification by insulin enhances methotrexate cytotoxicity in MCF-7 human breast cancer cells | Q34276737 | ||
Low-dose chemotherapy with insulin (insulin potentiation therapy) in combination with hormone therapy for treatment of castration-resistant prostate cancer | Q34278259 | ||
You are what you eat, or are you? The challenges of translating high-fat-fed rodents to human obesity and diabetes | Q34284239 | ||
The effect of intermittent energy and carbohydrate restriction v. daily energy restriction on weight loss and metabolic disease risk markers in overweight women | Q34339596 | ||
Peroxisome proliferator activated receptor α ligands as anticancer drugs targeting mitochondrial metabolism | Q36781253 | ||
Calorie restriction in humans inhibits the PI3K/AKT pathway and induces a younger transcription profile | Q37021961 | ||
Glucose as a prognostic factor in ovarian carcinoma | Q37114344 | ||
The GH-IGF1 axis and longevity. The paradigm of IGF1 deficiency. | Q37116517 | ||
Association between hyperglycemia and survival in patients with newly diagnosed glioblastoma | Q37155599 | ||
Insulin receptor phosphorylation by endogenous insulin or the insulin analog AspB10 promotes mammary tumor growth independent of the IGF-I receptor | Q37193406 | ||
FGF21 is not required for glucose homeostasis, ketosis or tumour suppression associated with ketogenic diets in mice | Q37485018 | ||
Cancer as a metabolic disease: implications for novel therapeutics | Q37616057 | ||
Ketogenic diets enhance oxidative stress and radio-chemo-therapy responses in lung cancer xenografts | Q37637990 | ||
Calories, carbohydrates, and cancer therapy with radiation: exploiting the five R's through dietary manipulation | Q37705691 | ||
The insulin and insulin-like growth factor receptor family in neoplasia: an update | Q37984217 | ||
Lifestyle and nutritional imbalances associated with Western diseases: causes and consequences of chronic systemic low-grade inflammation in an evolutionary context | Q38105236 | ||
Calorie restriction in overweight males ameliorates obesity-related metabolic alterations and cellular adaptations through anti-aging effects, possibly including AMPK and SIRT1 activation | Q38117013 | ||
Selectively starving cancer cells through dietary manipulation: methods and clinical implications | Q38120308 | ||
A new link between diabetes and cancer: enhanced WNT/β-catenin signaling by high glucose. | Q38139344 | ||
Targeting metabolism with a ketogenic diet during the treatment of glioblastoma multiforme | Q38179992 | ||
Caloric restriction and cancer: molecular mechanisms and clinical implications | Q38219267 | ||
Obesity, diabetes and cancer: insight into the relationship from a cohort with growth hormone receptor deficiency | Q38260335 | ||
Leptin levels in women with polycystic ovary syndrome before and after treatment with diazoxide | Q38333860 | ||
Toward a cancer-specific diet | Q38364452 | ||
Treatment of glioma patients with ketogenic diets: report of two cases treated with an IRB-approved energy-restricted ketogenic diet protocol and review of the literature | Q38389958 | ||
Pten-null tumors cohabiting the same lung display differential AKT activation and sensitivity to dietary restriction. | Q38449970 | ||
FGF21 as a mediator of adaptive responses to stress and metabolic benefits of anti-diabetic drugs. | Q38538911 | ||
Growth of human colon cancer cells in nude mice is delayed by ketogenic diet with or without omega-3 fatty acids and medium-chain triglycerides | Q38899556 | ||
Voltage-gated and ATP-sensitive K+ channels are associated with cell proliferation and tumorigenesis of human glioma | Q39052985 | ||
ATP-sensitive potassium channels control glioma cells proliferation by regulating ERK activity | Q39084326 | ||
Caloric restriction reduces edema and prolongs survival in a mouse glioma model | Q39148077 | ||
Correlation among insulin binding, degradation, and biological activity in human breast cancer cells in long-term tissue culture | Q39174840 | ||
Metabolism. Differential regulation of mTORC1 by leucine and glutamine | Q39211265 | ||
Glucose deprivation activates AMPK and induces cell death through modulation of Akt in ovarian cancer cells | Q39542918 | ||
Regulatory interrelationships for insulin and estrogen action in mammary tumors | Q39622616 | ||
Influence of insulin on estrogen-induced responses in the r3230ac mammary carcinoma | Q39728681 | ||
Glucose restriction can extend normal cell lifespan and impair precancerous cell growth through epigenetic control of hTERT and p16 expression | Q39761800 | ||
Ketone bodies inhibit the viability of human neuroblastoma cells. | Q39892401 | ||
Diazoxide-mediated growth inhibition in human lung cancer cells via downregulation of beta-catenin-mediated cyclin D1 transcription | Q39909465 | ||
Increased levels of superoxide and H2O2 mediate the differential susceptibility of cancer cells versus normal cells to glucose deprivation | Q39927250 | ||
Rapid loss of ATP by tumor cells deprived of glucose: Contrast to normal cells | Q40176533 | ||
Growth-stimulatory actions of insulin in vitro and in vivo | Q40179941 | ||
Physiological roles of ketone bodies as substrates and signals in mammalian tissues | Q40280929 | ||
High Glucose-Induced Expression of Proinflammatory Cytokine and Chemokine Genes in Monocytic Cells | Q40652063 | ||
Suppression of serum insulin by diazoxide reduces serum testosterone levels in obese women with polycystic ovary syndrome | Q41261033 | ||
Loss of acetoacetate coenzyme A transferase activity in tumours of peripheral tissues | Q41506230 | ||
Response of C57Bl/6 mice to a carbohydrate-free diet | Q41509403 | ||
Acetoacetate reduces growth and ATP concentration in cancer cell lines which over-express uncoupling protein 2. | Q41550485 | ||
Direct inhibition of growth and antagonism of insulin action by glucocorticoids in human breast cancer cells in culture | Q41613671 | ||
Ketolytic and glycolytic enzymatic expression profiles in malignant gliomas: implication for ketogenic diet therapy | Q41895412 | ||
Insulin-like growth factor-II: new roles for an old actor | Q42035390 | ||
A new benzothiadiazine derivative, LN 5330: effects on pancreatic hormones | Q42242647 | ||
Effects of diabetes and sex steroid hormones on insulin receptor tyrosine kinase activity in R3230AC mammary adenocarcinomas | Q42516569 | ||
Methionine restriction restores a younger metabolic phenotype in adult mice with alterations in fibroblast growth factor 21. | Q42566497 | ||
Effects of sulphonylureas and diazoxide on insulin secretion and nucleotide-sensitive channels in an insulin-secreting cell line | Q42848672 | ||
Calorie or carbohydrate restriction? The ketogenic diet as another option for supportive cancer treatment. | Q42971350 | ||
FoxO1 is involved in the antineoplastic effect of calorie restriction | Q43133444 | ||
Of mice and men. When it comes to studying ageing and the means to slow it down, mice are not just small humans | Q43205732 | ||
Biochemical determination of islet lysosomal enzyme activities following crinophagy-stimulating treatment with diazoxide in mice. | Q43533303 | ||
Response of IGF-1 to nutritional support in malnourished hospital patients: a possible indicator of short-term changes in nutritional status | Q43608503 | ||
Human leukemic cells: receptor binding and biological effects of insulin and insulin-like growth factors | Q43767618 | ||
Suppression of human tumor cell proliferation through mitochondrial targeting | Q44043398 | ||
Voltage-gated potassium ion channels in colon cancer. | Q44094664 | ||
Targeting insulin inhibition as a metabolic therapy in advanced cancer: a pilot safety and feasibility dietary trial in 10 patients | Q44266484 | ||
Opposite effects of tolbutamide and diazoxide on the ATP-dependent K+ channel in mouse pancreatic beta-cells | Q44273170 | ||
Persistent outpatient hyperglycemia is independently associated with decreased survival after primary resection of malignant brain astrocytomas | Q44281661 | ||
Decline of lactate in tumor tissue after ketogenic diet: in vivo microdialysis study in patients with head and neck cancer. | Q44415605 | ||
Relation between the duration of remission and hyperglycemia during induction chemotherapy for acute lymphocytic leukemia with a hyperfractionated cyclophosphamide, vincristine, doxorubicin, and dexamethasone/methotrexate-cytarabine regimen | Q44800298 | ||
Metastatic but not primary melanoma cell lines grow in vitro independently of exogenous growth factors | Q44864241 | ||
Suppression of serum insulin level by diazoxide does not alter serum testosterone or sex hormone-binding globulin levels in healthy, nonobese women | Q44971896 | ||
Effect of dietary macronutrient composition on AMPK and SIRT1 expression and activity in human skeletal muscle | Q45326878 | ||
Will calorie restriction work in humans? | Q34362501 | ||
Insulin receptor (IR) and insulin-like growth factor receptor 1 (IGF-1R) signaling systems: novel treatment strategies for cancer. | Q34391968 | ||
The ratio of macronutrients, not caloric intake, dictates cardiometabolic health, aging, and longevity in ad libitum-fed mice | Q34408951 | ||
The effects of intermittent or continuous energy restriction on weight loss and metabolic disease risk markers: a randomized trial in young overweight women | Q34474453 | ||
Dietary Protein to Carbohydrate Ratio and Caloric Restriction: Comparing Metabolic Outcomes in Mice | Q34478636 | ||
Hepatic SIRT1 attenuates hepatic steatosis and controls energy balance in mice by inducing fibroblast growth factor 21. | Q34494080 | ||
Body composition and hormonal responses to a carbohydrate-restricted diet | Q34524410 | ||
Role of glucose and ketone bodies in the metabolic control of experimental brain cancer | Q34542313 | ||
Diabetogenic glucose and insulin concentrations modulate transcriptome and protein levels involved in tumour cell migration, adhesion and proliferation | Q34543788 | ||
The calorically restricted ketogenic diet, an effective alternative therapy for malignant brain cancer | Q34576016 | ||
Growth of human gastric cancer cells in nude mice is delayed by a ketogenic diet supplemented with omega-3 fatty acids and medium-chain triglycerides. | Q34591316 | ||
Clinically defined type 2 diabetes mellitus and prognosis in early-stage breast cancer | Q34662865 | ||
Effects of a ketogenic diet on tumor metabolism and nutritional status in pediatric oncology patients: two case reports | Q34722625 | ||
The ketogenic diet for the treatment of malignant glioma | Q34757474 | ||
Caloric restriction in C57BL/6J mice mimics therapeutic fasting in humans | Q34804059 | ||
Long-term effects of calorie or protein restriction on serum IGF-1 and IGFBP-3 concentration in humans. | Q34849088 | ||
CHRONIC NEONATAL DIAZOXIDE THERAPY IS NOT ASSOCIATED WITH ADVERSE EFFECTS | Q34901780 | ||
Insulin receptor isoforms and insulin receptor/insulin-like growth factor receptor hybrids in physiology and disease. | Q35002762 | ||
Serum IL-6, TNFalpha and CRP levels in Greek colorectal cancer patients: prognostic implications | Q35011366 | ||
Acarbose, lente carbohydrate, and prebiotics promote metabolic health and longevity by stimulating intestinal production of GLP-1. | Q35047406 | ||
Effects of a ketogenic diet on the quality of life in 16 patients with advanced cancer: A pilot trial | Q35168645 | ||
Energy restriction and the risk of spontaneous mammary tumors in mice: a meta-analysis | Q35179102 | ||
Dietary components that regulate serum somatomedin-C concentrations in humans | Q35202621 | ||
Ketogenic Diet Impairs FGF21 Signaling and Promotes Differential Inflammatory Responses in the Liver and White Adipose Tissue | Q35606508 | ||
Inhibition of Neuroblastoma Tumor Growth by Ketogenic Diet and/or Calorie Restriction in a CD1-Nu Mouse Model | Q35656317 | ||
Nonobese diabetic mice express aspects of both type 1 and type 2 diabetes | Q35699988 | ||
Impact of glycemia on survival of glioblastoma patients treated with radiation and temozolomide. | Q35837629 | ||
A Periodic Diet that Mimics Fasting Promotes Multi-System Regeneration, Enhanced Cognitive Performance, and Healthspan. | Q35875208 | ||
Glucose deprivation activates a metabolic and signaling amplification loop leading to cell death | Q36096600 | ||
Impact of diabetes and hyperglycemia on survival in advanced breast cancer patients | Q36165176 | ||
The effects of graded levels of calorie restriction: II. Impact of short term calorie and protein restriction on circulating hormone levels, glucose homeostasis and oxidative stress in male C57BL/6 mice. | Q36414145 | ||
Dose-dependent effects of calorie restriction on gene expression, metabolism, and tumor progression are partially mediated by insulin-like growth factor-1 | Q36530674 | ||
Metabolic response to high-carbohydrate and low-carbohydrate meals in a nonhuman primate model. | Q36593099 | ||
Proinflammatory effects of glucose and anti-inflammatory effect of insulin: relevance to cardiovascular disease | Q36738682 | ||
The growth hormone: insulin-like growth factor 1 axis is a mediator of diet restriction-induced inhibition of mononuclear cell leukemia in Fischer rats. | Q54046567 | ||
Insulin resistance and tissue glycogen content in the tumor-bearing state. | Q54066543 | ||
Is profound peripheral insulin resistance in patients with pancreatic cancer caused by a tumor-associated factor? | Q54252640 | ||
Effects of caloric or protein restriction on insulin-like growth factor-I (IGF-I) and IGF-binding proteins in children and adults. | Q55063316 | ||
Cell biology. Making sense of amino acid sensing. | Q55068778 | ||
Expression of mouse sialic acid on gangliosides of a human glioma grown as a xenograft in SCID mice. | Q55476853 | ||
The western diet and lifestyle and diseases of civilization | Q56169471 | ||
Visceral obesity, metabolic syndrome, insulin resistance and cancer | Q57521562 | ||
A Low Carbohydrate, High Protein Diet Slows Tumor Growth and Prevents Cancer Initiation | Q60313824 | ||
Growth-promoting effect, biological activity, and binding of insulin in human intestinal cancer cells in culture | Q67265039 | ||
Antineoplastic efficacy of melphalan and N-(2-chloroethyl)-N-nitrosocarbamoyl-omega-lysine, in combination with diazoxide or insulin in autochthonous mammary carcinoma of the Sprague-Dawley rat | Q67276080 | ||
Diazoxide Infusion Test in Patients with Single Benign Insulinoma | Q67294970 | ||
Tumor cytokinetic response to total parenteral nutrition in patients with head and neck cancers | Q67984460 | ||
Treatment of hyperinsulinism with diazoxide over several years | Q69378887 | ||
Stimulation of tumor growth in adult rats in vivo during acute streptozotocin-induced diabetes | Q69745682 | ||
Characteristics of insulin receptors and insulin action in human myelogenous leukemia cell line K-562 | Q69938954 | ||
Effects of diazoxide-induced reversible diabetes on chemically induced autochthonous mammary carcinomas in Sprague-Dawley rats | Q69939020 | ||
Diazoxide in the management of patients with insulinoma | Q70147196 | ||
Retarded growth of murine tumors in vivo by insulin- and glucagon-stimulated immunity and phagocytosis | Q70149130 | ||
Identification of linoleic and arachidonic acids as the factors in hyperlipemic blood that increase [3H]thymidine incorporation in hepatoma 7288CTC perfused in situ | Q70387297 | ||
[Comparison of oral diazoxide and minoxidil in refractory hypertension] | Q71407315 | ||
Effect of insulin and of alloxan diabetes on growth of the rat mammary carcinoma in vivo | Q71607228 | ||
Effect of total parenteral nutrition on survival in advanced colon cancer | Q71645128 | ||
Effect of insulin on DNA synthesis and DNA polymerase activity in organ culture of rat mammary carcinoma, and the inflence of insulin pretreatment and of alloxan diabetes | Q71751184 | ||
Reversal of enhanced pancreatic cancer growth in diabetes by insulin1 | Q71968215 | ||
Effects of tumor removal and body weight loss on insulin resistance in patients with cancer | Q72041505 | ||
The effect of diazoxide-induced hormonal secretion on plasma triglyceride concentration in the rat | Q72152550 | ||
Reduction in serum leptin and IGF-1 but preserved T-lymphocyte numbers and activation after a ketogenic diet in rheumatoid arthritis patients | Q73795684 | ||
Dietary restriction reduces insulin-like growth factor I levels, which modulates apoptosis, cell proliferation, and tumor progression in p53-deficient mice | Q73838225 | ||
[Experiences with insulin & carbohydrate-reducing diet in incurable cancer] | Q74574212 | ||
Effect of insulin and glucagon on tumour growth | Q77195233 | ||
The effect of glucagon on tumor growth | Q78693135 | ||
Two cases of malignant tumors with metastases apparently treated successfully with hypoglycemic coma | Q78962934 | ||
Effect of energy substrate manipulation on tumour cell proliferation in parenterally fed cancer patients | Q79900533 | ||
Impact of nutrition support on treatment outcome in patients with locally advanced head and neck squamous cell cancer treated with definitive radiotherapy: a secondary analysis of RTOG trial 90-03 | Q81478502 | ||
P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
P6216 | copyright status | copyrighted | Q50423863 |
P433 | issue | 2 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | pharmacology | Q128406 |
P304 | page(s) | e193 | |
P577 | publication date | 2016-02-15 | |
P1433 | published in | Oncogenesis | Q27724395 |
P1476 | title | Dietary and pharmacological modification of the insulin/IGF-1 system: exploiting the full repertoire against cancer | |
P478 | volume | 5 |
Q47177087 | A framework to understand diet, physical activity, body weight, and cancer risk |
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Q34558255 | Beneficial effects of ketogenic diets for cancer patients: a realist review with focus on evidence and confirmation. |
Q42364184 | Diazoxide for Lowering Insulin Levels in Breast Cancer Patients. |
Q92856323 | Dietary Carbohydrate Promotes Cell Survival in Cancer Via the Up-Regulation of Fat Mass and Obesity-Associated Gene Expression Level |
Q92107957 | Dietary protein sources and tumoral overexpression of RhoA, VEGF-A and VEGFR2 genes among breast cancer patients |
Q41660847 | Glycans as Regulatory Elements of the Insulin/IGF System: Impact in Cancer Progression. |
Q47379404 | Immune by Heart: Unexpected Observations Inspiring Perspective Therapeutic/Preventive Strategies against Cancer |
Q41843138 | Low carbohydrate diet prevents Mcl-1-mediated resistance to BH3-mimetics |
Q91742566 | Metformin ameliorates bleomycin-induced pulmonary fibrosis in mice by suppressing IGF-1 |
Q53326526 | Need for new review of article on ketogenic dietary regimes for cancer patients. |
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Q64972488 | The Impact of Serum Glucose, Anti-Diabetic Agents, and Statin Usage in Non-small Cell Lung Cancer Patients Treated With Definitive Chemoradiation. |
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Q52805810 | [Ketogenic diet: insufficient study results and lack of positive clinical benefits]. |
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