Cabozantinib in the treatment of advanced renal cell carcinoma: clinical trial evidence and experience

scientific article

Cabozantinib in the treatment of advanced renal cell carcinoma: clinical trial evidence and experience is …
instance of (P31):
clinical trialQ30612
scholarly articleQ13442814

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P356DOI10.1177/1756287216663073
P932PMC publication ID5117166
P698PubMed publication ID27904650

P2093author name stringD. Y. C. Heng
J. M. Ruiz-Morales
P2860cites workmTOR inhibitors in advanced renal cell carcinomaQ24612127
Axitinib in the treatment of renal cell carcinoma: patient selection and perspectivesQ26751341
Renal cell carcinoma: histological classification and correlation with imaging findingsQ26799781
HGF/c-Met Acts as an Alternative Angiogenic Pathway in Sunitinib-Resistant TumorsQ42819341
Expression and localization of VEGF receptors in human fetal skeletal tissuesQ50780688
Renal cancer.Q50941188
Skeletal complications and survival in renal cancer patients with bone metastasesQ52847077
Efficacy of targeted therapies after PD-1/PD-L1 blockade in metastatic renal cell carcinomaQ53354192
Cabozantinib in Advanced Renal Cell Carcinoma: Is it a METEOR?Q54224544
Next-generation Sequencing of Urologic Cancers: Next Is NowQ57288433
Out of air is not out of actionQ58199718
Lenvatinib, everolimus, and the combination in patients with metastatic renal cell carcinoma: a randomised, phase 2, open-label, multicentre trialQ59571527
Hepatocyte growth factor can substitute for M-CSF to support osteoclastogenesisQ79193387
Genetic basis for kidney cancer: opportunity for disease-specific approaches to therapyQ81267790
Comprehensive molecular characterization of clear cell renal cell carcinomaQ27852374
Integrated molecular analysis of clear-cell renal cell carcinomaQ27852382
Overall survival and updated results for sunitinib compared with interferon alfa in patients with metastatic renal cell carcinomaQ28247085
Efficacy of everolimus in advanced renal cell carcinoma: a double-blind, randomised, placebo-controlled phase III trialQ29618031
Temsirolimus, interferon alfa, or both for advanced renal-cell carcinomaQ29618608
Pazopanib versus sunitinib in metastatic renal-cell carcinomaQ33409916
Impact of bone and liver metastases on patients with renal cell carcinoma treated with targeted therapyQ34007924
Cabozantinib in progressive medullary thyroid cancerQ34185084
Direct regulation of GAS6/AXL signaling by HIF promotes renal metastasis through SRC and MET.Q34217927
Cabozantinib versus Everolimus in Advanced Renal-Cell CarcinomaQ34495684
Randomized phase III trial of high-dose interleukin-2 versus subcutaneous interleukin-2 and interferon in patients with metastatic renal cell carcinomaQ34553839
Bevacizumab plus interferon alfa-2a for treatment of metastatic renal cell carcinoma: a randomised, double-blind phase III trialQ34586436
Comparative effectiveness of axitinib versus sorafenib in advanced renal cell carcinoma (AXIS): a randomised phase 3 trial.Q34633525
Axitinib versus sorafenib as second-line treatment for advanced renal cell carcinoma: overall survival analysis and updated results from a randomised phase 3 trialQ34650664
Drug development of MET inhibitors: targeting oncogene addiction and expedienceQ34782774
Survival outcome and treatment response of patients with late relapse from renal cell carcinoma in the era of targeted therapy.Q34896252
Patterns of disease progression in metastatic renal cell carcinoma patients treated with antivascular agents and interferon: impact of therapy on recurrence patterns and outcome measuresQ35684252
Taking aim at Mer and Axl receptor tyrosine kinases as novel therapeutic targets in solid tumorsQ35927501
c-Met is a prognostic marker and potential therapeutic target in clear cell renal cell carcinomaQ36551653
Activity of XL184 (Cabozantinib), an Oral Tyrosine Kinase Inhibitor, in Patients With Medullary Thyroid CancerQ36822111
Targeting MET and Vascular Endothelial Growth Factor Receptor Signaling in Castration-Resistant Prostate CancerQ36931715
Kinase requirements in human cells: III. Altered kinase requirements in VHL-/- cancer cells detected in a pilot synthetic lethal screenQ36954859
Molecular biology of renal cortical tumorsQ37320998
Controlling escape from angiogenesis inhibitorsQ37672654
VHL and HIF signalling in renal cell carcinogenesisQ37708208
Targeting MET in cancer: rationale and progressQ37978193
Cabozantinib: a MET, RET, and VEGFR2 tyrosine kinase inhibitorQ38206456
A phase I study of cabozantinib (XL184) in patients with renal cell cancer.Q38430335
Therapeutic Strategies for Patients With Metastatic Renal Cell Carcinoma in Whom First-Line Vascular Endothelial Growth Factor Receptor-Directed Therapies Fail.Q38832659
Targeting MET and AXL overcomes resistance to sunitinib therapy in renal cell carcinomaQ38835745
Cabozantinib versus everolimus in advanced renal cell carcinoma (METEOR): final results from a randomised, open-label, phase 3 trial.Q38859789
Hepatocyte growth factor-induced BMP-2 expression is mediated by c-Met receptor, FAK, JNK, Runx2, and p300 pathways in human osteoblastsQ39364581
Hepatocyte growth factor is secreted by osteoblasts and cooperatively permits the survival of haematopoietic progenitors.Q40828878
Expression of vascular endothelial growth factors and their receptors during osteoblast differentiationQ40881030
Nivolumab versus Everolimus in Advanced Renal-Cell CarcinomaQ41316099
P433issue6
P407language of work or nameEnglishQ1860
P921main subjectrenal cell carcinomaQ1164529
P304page(s)338-347
P577publication date2016-12-01
P13046publication type of scholarly workreview articleQ7318358
P1433published inTherapeutic advances in urologyQ26842184
P1476titleCabozantinib in the treatment of advanced renal cell carcinoma: clinical trial evidence and experience
P478volume8

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cites work (P2860)
Q47143379A network meta-analysis of short-term efficacy of different single-drug targeted therapies in the treatment of renal cell carcinoma
Q39235281An overview of quinoline as a privileged scaffold in cancer drug discovery
Q47177700Differential expression of c-Met between primary and metastatic sites in clear-cell renal cell carcinoma and its association with PD-L1 expression
Q92707858First-in-human phase I study of BPI-9016M, a dual MET/Axl inhibitor, in patients with non-small cell lung cancer
Q42682360Neutrophil lymphocyte ratio and duration of prior anti-angiogenic therapy as biomarkers in metastatic RCC receiving immune checkpoint inhibitor therapy.
Q58585079Non-Clear Cell Renal Cell Carcinoma: Current Management and Best Practice
Q91809322The Interplay between Inflammation, Anti-Angiogenic Agents, and Immune Checkpoint Inhibitors: Perspectives for Renal Cell Cancer Treatment
Q90611117The identification of patient-specific mutations reveals dual pathway activation in most patients with melanoma and activated receptor tyrosine kinases in BRAF/NRAS wild-type melanomas

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