Exploring the developmental mechanisms underlying Wolf-Hirschhorn Syndrome: Evidence for defects in neural crest cell migration

scientific article

Exploring the developmental mechanisms underlying Wolf-Hirschhorn Syndrome: Evidence for defects in neural crest cell migration is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1016/J.YDBIO.2016.10.012
P932PMC publication ID5193094
P698PubMed publication ID27777068

P50authorLaura Anne LoweryQ57321295
P2093author name stringErin L. Rutherford
P2860cites workComparative analysis of a novel gene from the Wolf-Hirschhorn/Pitt-Rogers-Danks syndrome critical regionQ22010268
Development and evolution of the neural crest: an overviewQ22337309
TACC1-chTOG-Aurora A protein complex in breast cancerQ24299319
Cellular signaling by fibroblast growth factor receptorsQ24301087
WHSC1, a 90 kb SET domain-containing gene, expressed in early development and homologous to a Drosophila dysmorphy gene maps in the Wolf-Hirschhorn syndrome critical region and is fused to IgH in t(4;14) multiple myelomaQ24322575
Fibroblast growth factor receptor 3 is a negative regulator of bone growthQ24322706
Mapping the Wolf-Hirschhorn syndrome phenotype outside the currently accepted WHS critical region and defining a new critical region, WHSCR-2.Q24531948
The centrosomal protein TACC3 is essential for hematopoietic stem cell function and genetically interfaces with p53-regulated apoptosisQ24534711
Aspm specifically maintains symmetric proliferative divisions of neuroepithelial cellsQ24550947
Autosomal Recessive Primary Microcephaly (MCPH): clinical manifestations, genetic heterogeneity and mutation continuumQ24570114
The TACC domain identifies a family of centrosomal proteins that can interact with microtubulesQ24672611
The ch-TOG/XMAP215 protein is essential for spindle pole organization in human somatic cellsQ24672810
The LETM1/YOL027 gene family encodes a factor of the mitochondrial K+ homeostasis with a potential role in the Wolf-Hirschhorn syndrome.Q27932161
LETM1, a novel gene encoding a putative EF-hand Ca(2+)-binding protein, flanks the Wolf-Hirschhorn syndrome (WHS) critical region and is deleted in most WHS patientsQ28116065
Twist, a master regulator of morphogenesis, plays an essential role in tumor metastasisQ28131703
First known microdeletion within the Wolf-Hirschhorn syndrome critical region refines genotype-phenotype correlationQ28205042
The etiology of Wolf-Hirschhorn syndromeQ28236976
IQGAP1: a key regulator of adhesion and migrationQ28250427
FGF receptors: cancer biology and therapeuticsQ28291186
A transcript map of the newly defined 165 kb Wolf-Hirschhorn syndrome critical regionQ28305534
Fibroblast growth factor receptors cooperate to regulate neural progenitor properties in the developing midbrain and hindbrainQ28506314
Interaction between FOG-1 and the corepressor C-terminal binding protein is dispensable for normal erythropoiesis in vivoQ28510968
Disruption of fibroblast growth factor receptor 3 signaling results in defects in cellular differentiation, neuronal patterning, and hearing impairmentQ28511525
Inactivation of the beta-catenin gene by Wnt1-Cre-mediated deletion results in dramatic brain malformation and failure of craniofacial developmentQ28513519
Isolation and characterization of AINT: a novel ARNT interacting protein expressed during murine embryonic developmentQ28585602
Wnt signaling mediates regional specification in the vertebrate faceQ28588683
A histone H3 lysine 36 trimethyltransferase links Nkx2-5 to Wolf-Hirschhorn syndromeQ28593584
TACC3-ch-TOG track the growing tips of microtubules independently of clathrin and Aurora-A phosphorylationQ29347519
Mitochondrial reactive oxygen species trigger hypoxia-induced transcriptionQ29614203
Reactive oxygen species generated at mitochondrial complex III stabilize hypoxia-inducible factor-1alpha during hypoxia: a mechanism of O2 sensingQ29617570
The Xenopus embryo as a model system for studies of cell migrationQ30435289
FGF8 signaling is chemotactic for cardiac neural crest cellsQ30500159
Xenopus TACC2 is a microtubule plus end-tracking protein that can promote microtubule polymerization during embryonic development.Q30822145
Cyclin D1 is not an immediate target of beta-catenin following Apc loss in the intestineQ33216786
Xenopus skip modulates Wnt/beta-catenin signaling and functions in neural crest induction.Q33526741
The target of the NSD family of histone lysine methyltransferases depends on the nature of the substrateQ33553524
Primary microcephaly: do all roads lead to Rome?Q33629131
TACC2 is an androgen-responsive cell cycle regulator promoting androgen-mediated and castration-resistant growth of prostate cancerQ33636574
LETM1, a gene deleted in Wolf-Hirschhorn syndrome, encodes an evolutionarily conserved mitochondrial proteinQ33974957
Dissection of Xenopus laevis neural crest for in vitro explant culture or in vivo transplantationQ34009403
WHSC1L1, on human chromosome 8p11.2, closely resembles WHSC1 and maps to a duplicated region shared with 4p16.3.Q34090593
Deficiency on the short arms of a chromosome No. 4Q34241073
Deletion of short arms of chromosome 4?5 in a child with defects of midline fusionQ34241369
The transforming acidic coiled coil proteins interact with nuclear histone acetyltransferasesQ34295310
Wolf-Hirschhorn syndrome facial dysmorphic features in a patient with a terminal 4p16.3 deletion telomeric to the WHSCR and WHSCR 2 regionsQ34325417
LETM1-dependent mitochondrial Ca2+ flux modulates cellular bioenergetics and proliferation.Q34356130
TACC3 is a microtubule plus end-tracking protein that promotes axon elongation and also regulates microtubule plus end dynamics in multiple embryonic cell typesQ34428668
Wolf-Hirschhorn syndrome: A review and updateQ34488100
Duplication of the Wolf-Hirschhorn syndrome critical region causes neurodevelopmental delay.Q51854794
TWIST activation by hypoxia inducible factor-1 (HIF-1): implications in metastasis and development.Q51952297
Essential role of non-canonical Wnt signalling in neural crest migration.Q52051294
TACC3 promotes epithelial-mesenchymal transition (EMT) through the activation of PI3K/Akt and ERK signaling pathways.Q53123068
A novel 4p16.3 microduplication distal to WHSC1 and WHSC2 characterized by oligonucleotide array with new phenotypic features.Q53228045
[Aurora kinases and cancer]Q64132609
TACC3 is required for the proper mitosis of sclerotome mesenchymal cells during formation of the axial skeletonQ79947120
The transforming acidic coiled coil 3 protein is essential for spindle-dependent chromosome alignment and mitotic survivalQ34659420
Epigenetic regulation in neural crest developmentQ34663839
Neural crest specification and migration independently require NSD3-related lysine methyltransferase activity.Q34680417
Coiled-coil coactivators play a structural role mediating interactions in hypoxia-inducible factor heterodimerizationQ35199417
Histone lysine methyltransferase Wolf-Hirschhorn syndrome candidate 1 is involved in human carcinogenesis through regulation of the Wnt pathwayQ35444274
Xenopus TACC1 is a microtubule plus-end tracking protein that can regulate microtubule dynamics during embryonic developmentQ35903431
Cdk5rap2 exposes the centrosomal root of microcephaly syndromesQ36021561
FGFR3-TACC3: A novel gene fusion in cervical cancerQ36039883
Neural Explant Cultures from Xenopus laevisQ36375166
The multiple myeloma associated MMSET gene contributes to cellular adhesion, clonogenic growth, and tumorigenicity.Q36384699
The histone methyltransferase MMSET/WHSC1 activates TWIST1 to promote an epithelial-mesenchymal transition and invasive properties of prostate cancerQ36390674
The control of histone lysine methylation in epigenetic regulationQ36571342
WNT/β-catenin signaling mediates human neural crest induction via a pre-neural border intermediate.Q36597429
Letm1, the mitochondrial Ca2+/H+ antiporter, is essential for normal glucose metabolism and alters brain function in Wolf-Hirschhorn syndrome.Q36932269
Set2 mediated H3 lysine 36 methylation: regulation of transcription elongation and implications in organismal developmentQ37158054
The TACC proteins: TACC-ling microtubule dynamics and centrosome functionQ37227249
Mouse models of Wolf-Hirschhorn syndromeQ37302911
IQGAP1 protein regulates nuclear localization of β-catenin via importin-β5 protein in Wnt signalingQ37404988
Oxidative stress, neurodegeneration, and the balance of protein degradation and protein synthesisQ38045663
The role of the non-canonical Wnt-planar cell polarity pathway in neural crest migrationQ38170173
Unusual 4p16.3 deletions suggest an additional chromosome region for the Wolf-Hirschhorn syndrome-associated seizures disorder.Q38307737
MMSET deregulation affects cell cycle progression and adhesion regulons in t(4;14) myeloma plasma cells.Q39908262
The MMSET protein is a histone methyltransferase with characteristics of a transcriptional corepressorQ40031496
Transforming acidic coiled-coil protein 3 (TACC3) controls friend of GATA-1 (FOG-1) subcellular localization and regulates the association between GATA-1 and FOG-1 during hematopoiesisQ40575090
Direct evidence for a role of beta-catenin/LEF-1 signaling pathway in induction of EMT.Q40721147
CPEB, maskin, and cyclin B1 mRNA at the mitotic apparatus: implications for local translational control of cell divisionQ40841882
Meier-Gorlin syndrome and Wolf-Hirschhorn syndrome: two developmental disorders highlighting the importance of efficient DNA replication for normal development and neurogenesisQ41932004
Functional characterization of the zebrafish WHSC1-related gene, a homolog of human NSD2Q42858891
Directional cell migration in vivo: Wnt at the crestQ43190503
Quantitative analysis of orofacial development and median clefts in Xenopus laevisQ44992991
Ectodermal Wnt function as a neural crest inducer.Q46043546
Molecular interactions coordinating the development of the forebrain and face.Q46567732
Lung tumor-associated dendritic cell-derived resistin promoted cancer progression by increasing Wolf-Hirschhorn syndrome candidate 1/Twist pathwayQ47753819
Skeletal overgrowth and deafness in mice lacking fibroblast growth factor receptor 3.Q49042849
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectWolf-Hirschhorn syndromeQ610075
cell motilityQ14873676
embryonic structureQ30062554
physiological phenomenonQ66615932
P1104number of pages10
P5008on focus list of Wikimedia projectScienceSourceQ55439927
P304page(s)1-10
P577publication date2016-12-01
P1433published inDevelopmental BiologyQ3025402
P1476titleExploring the developmental mechanisms underlying Wolf-Hirschhorn Syndrome: Evidence for defects in neural crest cell migration
P478volume420

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cites work (P2860)
Q90437192Global regulation of the histone mark H3K36me2 underlies epithelial plasticity and metastatic progression
Q92088601Nonossified cervical vertebrae in Wolf-Hirschhorn Syndrome: A case report
Q91811171The Many Faces of Xenopus: Xenopus laevis as a Model System to Study Wolf-Hirschhorn Syndrome
Q58718492The biological significance of histone modifiers in multiple myeloma: clinical applications
Q93001306Whsc1 links pluripotency exit with mesendoderm specification
Q64119282Wolf-Hirschhorn Syndrome-Associated Genes Are Enriched in Motile Neural Crest Cells and Affect Craniofacial Development in