Looking Beyond the Terrestrial: The Potential of Seaweed Derived Bioactives to Treat Non-Communicable Diseases

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Looking Beyond the Terrestrial: The Potential of Seaweed Derived Bioactives to Treat Non-Communicable Diseases is …
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scholarly articleQ13442814
review articleQ7318358

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P356DOI10.3390/MD14030060
P932PMC publication ID4820313
P698PubMed publication ID26999166

P50authorCatherine StantonQ56605088
Reynolds Paul RossQ62566537
P2093author name stringGerald F Fitzgerald
Kenneth G Collins
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In vitro and in vivo hypoglycemic effects of brown algal fucoidans.Q51293699
Fucoidan from sea cucumber may improve hepatic inflammatory response and insulin resistance in mice.Q51597890
Antioxidant activities of crude extracts of fucoidan extracted from Sargassum glaucescens by a compressional-puffing-hydrothermal extraction process.Q53246759
Potent suppressive effect of a Japanese edible seaweed, Enteromorpha prolifera (Sujiao-nori) on initiation and promotion phases of chemically induced mouse skin tumorigenesis.Q53421532
Effects of Ecklonia cava ethanolic extracts on airway hyperresponsiveness and inflammation in a murine asthma model: role of suppressor of cytokine signaling.Q53563238
Anti-proliferative and potential anti-diabetic effects of phenolic-rich extracts from edible marine algaeQ54297935
The effect of dietary laminarin and fucoidan in the diet of the weanling piglet on performance, selected faecal microbial populations and volatile fatty acid concentrations.Q54388239
Reduction of colitis by prebiotics in HLA-B27 transgenic rats is associated with microflora changes and immunomodulation.Q54634996
Polyphenol-rich seaweed (Eucheuma cottonii) extract suppresses breast tumour via hormone modulation and apoptosis inductionQ57588813
Dietary fiber, amino acid, fatty acid and tocopherol contents of the edible seaweeds Ulva lactuca and Durvillaea antarcticaQ58494160
Effects of diet enriched with restructured meats, containing Himanthalia elongata, on hypercholesterolaemic induction, CYP7A1 expression and antioxidant enzyme activity and expression in growing ratsQ59202945
Dietary fibre from edible seaweeds: Chemical structure, physicochemical properties and effects on cholesterol metabolismQ59203005
Fermentative ability of alginate-prebiotic encapsulated Lactobacillus acidophilus and survival under simulated gastrointestinal conditionsQ59324178
The effect of dietary Laminaria-derived laminarin and fucoidan on nutrient digestibility, nitrogen utilisation, intestinal microflora and volatile fatty acid concentration in pigsQ63849581
Effects of a sodium-potassium ion-exchanging seaweed preparation in mild hypertensionQ67945461
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Immunonutrition: role of biosurfactants, fiber, and probiotic bacteriaQ74822286
Fucoidan prevents C epsilon germline transcription and NFkappaB p52 translocation for IgE production in B cellsQ79208667
Alpha-amylase inhibitors from Brazilian seaweeds and their hypoglycemic potentialQ79305645
Prebiotic effects of neoagaro-oligosaccharides prepared by enzymatic hydrolysis of agaroseQ80263391
Fucoidan stimulation induces a functional maturation of human monocyte-derived dendritic cellsQ81949990
Purification and characterization of a novel angiotensin-I converting enzyme (ACE) inhibitory peptide derived from enzymatic hydrolysate of grass carp proteinQ82595348
Cytoprotective effects of fucoidan, an algae-derived polysaccharide on 5-fluorouracil-treated dendritic cellsQ83426928
Comparing anti-hyperglycemic activity and acute oral toxicity of three different trivalent chromium complexes in miceQ83514571
Ishige okamurae ameliorates hyperglycemia and insulin resistance in C57BL/KsJ-db/db miceQ83826860
Insulinotrophic and hypolipidemic effects of Ecklonia cava in streptozotocin-induced diabetic miceQ84041246
In vitro cytotoxic effect of ethanol extract prepared from sporophyll of Undaria pinnatifida on human colorectal cancer cellsQ84171323
A glycoprotein from Laminaria japonica induces apoptosis in HT-29 colon cancer cellsQ84547215
Antihypertensive effects of Undaria pinnatifida (wakame) peptide on blood pressure in spontaneously hypertensive ratsQ44889951
Telomerase inhibition by sulfoquinovosyldiacylglycerol from edible purple laver (Porphyra yezoensis).Q44972513
A revised structure for fucoidan may explain some of its biological activities.Q45093121
Fucoxanthin induces apoptosis and enhances the antiproliferative effect of the PPARgamma ligand, troglitazone, on colon cancer cells.Q45145616
Omega-3 fatty acids and selenium as coronary heart disease risk modifying factors in Asian Indian and Chinese males.Q45161034
Lower intake of magnesium and dietary fiber increases the incidence of type 2 diabetes in TaiwaneseQ45241700
The α-amylase and α-glucosidase inhibitory effects of Irish seaweed extracts.Q45342329
Dietary intake, eating habits, and metabolic syndrome in Korean men.Q45775298
Unhealthy dietary patterns associated with inflammation and endothelial dysfunction in type 1 diabetes: the EURODIAB study.Q45915503
Effect of season on the composition of bioactive polysaccharides from the brown seaweed Saccharina longicruris.Q45989530
Diphlorethohydroxycarmalol isolated from Ishige okamurae, a brown algae, a potent alpha-glucosidase and alpha-amylase inhibitor, alleviates postprandial hyperglycemia in diabetic mice.Q45989697
Anti-hyperglycemic and antigenotoxic potential of Ulva rigida ethanolic extract in the experimental diabetes mellitus.Q46021655
Induction of apoptosis by phloroglucinol derivative from Ecklonia Cava in MCF-7 human breast cancer cells.Q46037532
Photoprotective effect of Undaria crenata against ultraviolet B-induced damage to keratinocytesQ46530084
Radioprotective properties of eckol against ionizing radiation in miceQ46737623
Attenuation of streptozotocin-induced diabetic retinopathy with low molecular weight fucoidan via inhibition of vascular endothelial growth factorQ47226139
Antioxidant activity of low molecular weight alginate produced by thermal treatmentQ47345539
In vitro fermentation and prebiotic potential of novel low molecular weight polysaccharides derived from agar and alginate seaweedsQ47355089
Combating pediatric obesity in Germany: the role of economic findings in informing policyQ38068459
Brown seaweed fucoidan: biological activity and apoptosis, growth signaling mechanism in cancerQ38118543
Brown alga Ecklonia cava attenuates type 1 diabetes by activating AMPK and Akt signaling pathwaysQ38491076
Anti-asthmatic effect of marine red alga (Laurencia undulata) polyphenolic extracts in a murine model of asthmaQ38497551
Structural characterization and effect on anti-angiogenic activity of a fucoidan from Sargassum fusiformeQ38819360
Structural elucidation of polysaccharide fractions from the brown alga Coccophora langsdorfii and in vitro investigation of their anticancer activityQ38829060
Marine algal fucoxanthin inhibits the metastatic potential of cancer cellsQ39096100
Preparation of low molecular weight fucoidan by gamma-irradiation and its anticancer activityQ39116192
Doxorubicin loading fucoidan acetate nanoparticles for immune and chemotherapy in cancer treatmentQ39173113
The effects of Caulerpa microphysa enzyme-digested extracts on ACE-inhibitory activity and in vitro anti-tumour propertiesQ39188373
Evaluation of selected tropical seaweeds for in vitro anti-trichomonal activity.Q39264975
Carotenoids reverse multidrug resistance in cancer cells by interfering with ABC-transportersQ39318483
Evaluation of phenolic contents and antioxidant activities of brown seaweeds belonging to Turbinaria spp. (Phaeophyta, Sargassaceae) collected from Gulf of MannarQ39342431
Sulfated polysaccharides from brown seaweeds Saccharina japonica and Undaria pinnatifida: isolation, structural characteristics, and antitumor activityQ39453425
Fucoidan from Sargassum sp. and Fucus vesiculosus reduces cell viability of lung carcinoma and melanoma cells in vitro and activates natural killer cells in mice in vivoQ39533776
Identification and in vitro anti-esophageal cancer activity of a series of halogenated monoterpenes isolated from the South African seaweeds Plocamium suhrii and Plocamium cornutumQ39578003
Non-communicable diseases: calling healthcare educators to actionQ39605459
In vitro antioxidant and inhibitory potential of Terminalia bellerica and Emblica officinalis fruits against LDL oxidation and key enzymes linked to type 2 diabetesQ39643510
Inhibition of proliferation of a hepatoma cell line by fucoxanthin in relation to cell cycle arrest and enhanced gap junctional intercellular communicationQ39802253
Implication of mitogen-activated protein kinase in the induction of G1 cell cycle arrest and gadd45 expression by the carotenoid fucoxanthin in human cancer cellsQ39806926
In vitro cancer chemopreventive properties of polysaccharide extract from the brown alga, Sargassum latifolium.Q39869446
Structural characteristics and in vitro macrophage activation of acetyl fucoidan from Cladosiphon okamuranusQ39883564
A polysaccharide of the marine alga Capsosiphon fulvescens induces apoptosis in AGS gastric cancer cells via an IGF-IR-mediated PI3K/Akt pathwayQ40162064
Porphyran induces apoptosis related signal pathway in AGS gastric cancer cell linesQ40250173
Antioxidant and antiproliferative activities of extracts from a variety of edible seaweedsQ40301039
Antiproliferative and antioxidant properties of an enzymatic hydrolysate from brown alga, Ecklonia cavaQ40308893
Plocoralides A-C, polyhalogenated monoterpenes from the marine alga Plocamium corallorhiza.Q40415393
In vitro anti-HIV-1 activity of fucoidan from Sargassum swartziiQ41211889
Fucoxanthin exerts differing effects on 3T3-L1 cells according to differentiation stage and inhibits glucose uptake in mature adipocytesQ42810183
Petalonia improves glucose homeostasis in streptozotocin-induced diabetic miceQ42811720
Fucoidan from the sporophyll of Undaria pinnatifida suppresses adipocyte differentiation by inhibition of inflammation-related cytokines in 3T3-L1 cellsQ42833153
Oral administration of mannitol may be an effective treatment for ischemia-reperfusion injuryQ42923217
Cardioprotective activity of Cladosiphon okamuranus fucoidan against isoproterenol induced myocardial infarction in ratsQ42967375
Composition and antioxidant capacity of low-salt meat emulsion model systems containing edible seaweedsQ43087024
Protective effect of diphlorethohydroxycarmalol isolated from Ishige okamurae against high glucose-induced-oxidative stress in human umbilical vein endothelial cellsQ43153871
Differences in satiety effects of alginate- and whey protein-based foodsQ43167031
Preventive effects of low molecular mass potassium alginate extracted from brown algae on DOCA salt-induced hypertension in ratsQ43237017
Cardiac mortality is associated with low levels of omega-3 and omega-6 fatty acids in the heart of cadavers with a history of coronary heart disease.Q43241124
Potential antioxidant and anticoagulant capacity of low molecular weight fucoidan fractions extracted from Laminaria japonicaQ43250257
Siphonaxanthin, a marine carotenoid from green algae, effectively induces apoptosis in human leukemia (HL-60) cells.Q44055666
The lipidic extract of the seaweed Gracilariopsis longissima (Rhodophyta, Gracilariales): a potential resource for biotechnological purposes?Q44395341
Comparative proteome analysis of Bifidobacterium longum subsp. infantis grown on β-glucans from different sources and a model for their utilizationQ44606128
P275copyright licenseCreative Commons AttributionQ6905323
P6216copyright statuscopyrightedQ50423863
P433issue3
P407language of work or nameEnglishQ1860
P921main subjectseaweedQ237169
drug discoveryQ1418791
traditional Asian medicineQ3439913
P304page(s)60
P577publication date2016-03-18
P1433published inMarine DrugsQ2122804
P1476titleLooking Beyond the Terrestrial: The Potential of Seaweed Derived Bioactives to Treat Non-Communicable Diseases
P478volume14

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cites work (P2860)
Q46295602Antioxidant activity of a halogenated monoterpene isolated from a Namibian marine algal Plocamium species
Q36304654Bioactive Peptide of Marine Origin for the Prevention and Treatment of Non-Communicable Diseases
Q47262178Bioactive Peptides Derived from Seaweed Protein and Their Health Benefits: Antihypertensive, Antioxidant, and Antidiabetic Properties.
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Q36359318Melanoma and brown seaweed: an integrative hypothesis
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Q64936930Risks and benefits of consuming edible seaweeds.
Q92703741Vitamin K as a Diet Supplement with Impact in Human Health: Current Evidence in Age-Related Diseases

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