Iron, oxygen, and the pulmonary circulation

scientific article

Iron, oxygen, and the pulmonary circulation is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1152/JAPPLPHYSIOL.00179.2015
P3181OpenCitations bibliographic resource ID1900931
P932PMC publication ID4683351
P698PubMed publication ID26066825

P50authorMatthew C FriseQ57497117
Peter A. RobbinsQ43064204
P2093author name stringMatthew C. Frise
Peter A. Robbins
P2860cites workHIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensingQ24291102
Normoxic stabilization of hypoxia-inducible factor-1alpha by modulation of the labile iron pool in differentiating U937 macrophages: effect of natural resistance-associated macrophage protein 1Q24306209
Sequencing of 50 human exomes reveals adaptation to high altitudeQ24599025
Cardiopulmonary function in two human disorders of the hypoxia-inducible factor (HIF) pathway: von Hippel-Lindau disease and HIF-2alpha gain-of-function mutationQ24613597
Natural selection on EPAS1 (HIF2alpha) associated with low hemoglobin concentration in Tibetan highlandersQ24623640
Iron regulates ferritin mRNA translation through a segment of its 5' untranslated regionQ24632213
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Inappropriate expression of hepcidin is associated with iron refractory anemia: implications for the anemia of chronic diseaseQ28209487
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Intravenous iron supplementation may protect against acute mountain sickness: a randomized, double-blinded, placebo-controlled trialQ57099992
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Stress Doppler echocardiography for identification of susceptibility to high altitude pulmonary edemaQ57113288
The Changes in the Breathing and the Blood at Various High AltitudesQ57229779
Range of tricuspid regurgitation velocity at rest and during exercise in normal adult men: implications for the diagnosis of pulmonary hypertensionQ63321244
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Comparison of several noninvasive methods for estimation of pulmonary artery pressureQ69451487
Chamber for controlling end-tidal gas tensions over sustained periods in humansQ72298443
Time course of the human pulmonary vascular response to 8 hours of isocapnic hypoxiaQ73757516
Effects of desferrioxamine on serum erythropoietin and ventilatory sensitivity to hypoxia in humansQ74113289
Erythropoietic effect of cobalt in patients with or without anemiaQ80321871
The influence of short periods of induced acute anoxia upon pulmonary artery pressures in manQ83251337
Unexplained iron deficiency in idiopathic and heritable pulmonary arterial hypertensionQ83378571
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Iron deficiency and raised hepcidin in idiopathic pulmonary arterial hypertension: clinical prevalence, outcomes, and mechanistic insights.Q50530002
IRP1 regulates erythropoiesis and systemic iron homeostasis by controlling HIF2α mRNA translation.Q50897468
The clinical significance of anaemia and disturbed iron homeostasis in chronic respiratory failure.Q51132510
Iron deficiency is common in idiopathic pulmonary arterial hypertensionQ51749929
Echocardiographic and invasive measurements of pulmonary artery pressure correlate closely at high altitude.Q52073422
Noninvasive estimation of right ventricular systolic pressure by Doppler ultrasound in patients with tricuspid regurgitation.Q52431887
Two temporal components within the human pulmonary vascular response to approximately 2 h of isocapnic hypoxia.Q53631134
Operation Everest II: elevated high-altitude pulmonary resistance unresponsive to oxygen.Q54402140
Observations on the Pulmonary Arterial Blood Pressure in the CatQ55922805
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Iron-dependent regulation of the divalent metal ion transporterQ28210422
The role of the iron responsive element in the control of ferroportin1/IREG1/MTP1 gene expressionQ28211300
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Genetic evidence for high-altitude adaptation in TibetQ28282435
Iron-regulatory proteins limit hypoxia-inducible factor-2alpha expression in iron deficiencyQ28297161
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Impaired physiological responses to chronic hypoxia in mice partially deficient for hypoxia-inducible factor 1alphaQ28508120
Purification and characterization of hypoxia-inducible factor 1Q28678375
Oxygen sensing by metazoans: the central role of the HIF hydroxylase pathwayQ29617805
Oxygen sensing by HIF hydroxylasesQ29617806
Hypoxic pulmonary vasoconstriction does not contribute to pulmonary blood flow heterogeneity in normoxia in normal supine humans.Q33389768
Point: Hypobaric hypoxia induces different physiological responses from normobaric hypoxiaQ33453128
Extent to which pulmonary vascular responses to PCO2 and PO2 play a functional role within the healthy human lungQ33841152
Beneficial effects of long-term intravenous iron therapy with ferric carboxymaltose in patients with symptomatic heart failure and iron deficiency†.Q34041875
Disruption of oxygen homeostasis underlies congenital Chuvash polycythemiaQ34157665
Genetic evidence of paleolithic colonization and neolithic expansion of modern humans on the tibetan plateauQ34345228
A genetic mechanism for Tibetan high-altitude adaptationQ34433853
Inhibition of prolyl hydroxylases increases erythropoietin production in ESRD.Q34457199
Variations in alveolar partial pressure for carbon dioxide and oxygen have additive not synergistic acute effects on human pulmonary vasoconstrictionQ34917895
Inhaled nitric oxide alters the distribution of blood flow in the healthy human lung, suggesting active hypoxic pulmonary vasoconstriction in normoxiaQ35034886
Contrasting effects of ascorbate and iron on the pulmonary vascular response to hypoxia in humansQ35094143
Anoxia and human pulmonary vascular resistanceQ35187284
Clinical demonstration of efficiency and reversibility of hypoxic pulmonary vasoconstriction in a patient presenting with unilateral incomplete bronchial occlusionQ35412335
HIF-1: an oxygen and metal responsive transcription factorQ35630605
Multiple factors affecting cellular redox status and energy metabolism modulate hypoxia-inducible factor prolyl hydroxylase activity in vivo and in vitroQ35641801
The long history of iron in the Universe and in health and diseaseQ35672646
A cross-sectional study of the prevalence and associations of iron deficiency in a cohort of patients with chronic obstructive pulmonary diseaseQ35844059
Physiological aspects of high-altitude pulmonary edemaQ36036151
Heterogeneous pulmonary blood flow in response to hypoxia: a risk factor for high altitude pulmonary edema?Q36353236
Deletion of iron regulatory protein 1 causes polycythemia and pulmonary hypertension in mice through translational derepression of HIF2α.Q36602744
Determinants of ventilation and pulmonary artery pressure during early acclimatization to hypoxia in humansQ36632620
Control of erythropoiesis in humans during prolonged exposure to the altitude of 6,542 m.Q36747675
Supplementation of iron in pulmonary hypertension: Rationale and design of a phase II clinical trial in idiopathic pulmonary arterial hypertensionQ36810774
Nutritional iron deficiencyQ36908053
Erythrocytosis and pulmonary hypertension in a mouse model of human HIF2A gain of function mutationQ36928937
The increase in pulmonary arterial pressure caused by hypoxia depends on iron statusQ37127689
Age-associated increases in pulmonary artery systolic pressure in the general populationQ37366030
Iron deficiency modifies gene expression variation induced by augmented hypoxia sensingQ37366148
Iron homeostasis and its interaction with prolyl hydroxylasesQ37570491
Therapeutic manipulation of the HIF hydroxylasesQ37597176
Iron sequestration and anemia of inflammationQ37604592
Anemia and iron deficiency in COPD patients: prevalence and the effects of correction of the anemia with erythropoiesis stimulating agents and intravenous ironQ37623876
Tibetans living at sea level have a hyporesponsive hypoxia-inducible factor system and blunted physiological responses to hypoxiaQ37679345
HIF and pulmonary vascular responses to hypoxiaQ37679350
Human adaptation to the hypoxia of high altitude: the Tibetan paradigm from the pregenomic to the postgenomic era.Q37679370
The HIF Pathway and ErythrocytosisQ37799606
Peopling the Tibetan plateau: insights from archaeologyQ37896078
Oxygen sensing, homeostasis, and diseaseQ37914865
The transforming growth factor-β-bone morphogenetic protein type signalling pathway in pulmonary vascular homeostasis and diseaseQ38104321
Desferrioxamine induces erythropoietin gene expression and hypoxia-inducible factor 1 DNA-binding activity: implications for models of hypoxia signal transductionQ38313423
Effects of iron supplementation and depletion on hypoxic pulmonary hypertension: two randomized controlled trialsQ38378487
Adaptation of iron requirement to hypoxic conditions at high altitudeQ38548790
The pulmonary vasculature--lessons from Tibetans and from rare diseases of oxygen sensingQ38635365
A prediction-correction scheme for forcing alveolar gases along certain time courses.Q39353254
Heterozygous deficiency of hypoxia-inducible factor-2alpha protects mice against pulmonary hypertension and right ventricular dysfunction during prolonged hypoxiaQ39752665
Iron homeostasis and pulmonary hypertension: iron deficiency leads to pulmonary vascular remodeling in the rat.Q41231467
Course of Pulmonary Hemodynamics in Patients with Chronic Obstructive Pulmonary DiseaseQ41551887
Increased hepcidin levels in high-altitude pulmonary edemaQ41590698
Hypoxia-inducible factor regulates hepcidin via erythropoietin-induced erythropoiesisQ42147890
Carotid body hyperplasia and enhanced ventilatory responses to hypoxia in mice with heterozygous deficiency of PHD2.Q43063832
Ferric carboxymaltose in patients with heart failure and iron deficiencyQ43240282
Desferrioxamine elevates pulmonary vascular resistance in humans: potential for involvement of HIF-1.Q43996721
Ferric carboxymaltose improves exercise capacity and quality of life in patients with pulmonary arterial hypertension and iron deficiency: a pilot studyQ44327077
Oxidative stress and renal injury with intravenous iron in patients with chronic kidney diseaseQ44900463
Adaptation of iron transport and metabolism to acute high-altitude hypoxia in mountaineersQ45140568
Iron deficiency in chronic heart failure: an international pooled analysisQ46257022
Separating the direct effect of hypoxia from the indirect effect of changes in cardiac output on the maximum pressure difference across the tricuspid valve in healthy humansQ47766597
Continuous wave Doppler determination of right ventricular pressure: a simultaneous Doppler-catheterization study in 127 patientsQ47914412
Iron deficiency defined as depleted iron stores accompanied by unmet cellular iron requirements identifies patients at the highest risk of death after an episode of acute heart failureQ48716818
P275copyright licenseCreative Commons AttributionQ6905323
P6216copyright statuscopyrightedQ50423863
P433issue12
P407language of work or nameEnglishQ1860
P921main subjecthypoxiaQ105688
inorganic compoundQ190065
oxygen consumptionQ70339049
P5008on focus list of Wikimedia projectScienceSourceQ55439927
P304page(s)1421-1431
P577publication date2015-06-11
2015-12-15
P1433published inJournal of Applied PhysiologyQ1091719
P1476titleIron, oxygen, and the pulmonary circulation
P478volume119

Reverse relations

cites work (P2860)
Q38548790Adaptation of iron requirement to hypoxic conditions at high altitude
Q36951774Clinical iron deficiency disturbs normal human responses to hypoxia
Q38975559Exaggerated pulmonary vascular response to acute hypoxia in older men.
Q89941197High geographic prevalence of pulmonary artery hypertension: associations with ethnicity, drug use, and altitude
Q64230500Iron Homeostasis in the Lungs-A Balance between Health and Disease
Q46513546Pollution Control Meets Sustainability: Structure-Activity Studies on New Iron Oxide-Based CO Oxidation Catalysts.

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