review article | Q7318358 |
scholarly article | Q13442814 |
P50 | author | Matthew C Frise | Q57497117 |
Peter A. Robbins | Q43064204 | ||
P2093 | author name string | Matthew C. Frise | |
Peter A. Robbins | |||
P2860 | cites work | HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing | Q24291102 |
Normoxic stabilization of hypoxia-inducible factor-1alpha by modulation of the labile iron pool in differentiating U937 macrophages: effect of natural resistance-associated macrophage protein 1 | Q24306209 | ||
Sequencing of 50 human exomes reveals adaptation to high altitude | Q24599025 | ||
Cardiopulmonary function in two human disorders of the hypoxia-inducible factor (HIF) pathway: von Hippel-Lindau disease and HIF-2alpha gain-of-function mutation | Q24613597 | ||
Natural selection on EPAS1 (HIF2alpha) associated with low hemoglobin concentration in Tibetan highlanders | Q24623640 | ||
Iron regulates ferritin mRNA translation through a segment of its 5' untranslated region | Q24632213 | ||
The human side of hypoxia-inducible factor | Q24646951 | ||
Hypoxia-inducible factors in physiology and medicine | Q27013770 | ||
Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation | Q27860876 | ||
Inappropriate expression of hepcidin is associated with iron refractory anemia: implications for the anemia of chronic disease | Q28209487 | ||
Hypoxic pulmonary vasoconstriction | Q57099542 | ||
Intravenous iron supplementation may protect against acute mountain sickness: a randomized, double-blinded, placebo-controlled trial | Q57099992 | ||
Hypoxic pulmonary vasoconstriction | Q57107929 | ||
Stress Doppler echocardiography for identification of susceptibility to high altitude pulmonary edema | Q57113288 | ||
The Changes in the Breathing and the Blood at Various High Altitudes | Q57229779 | ||
Range of tricuspid regurgitation velocity at rest and during exercise in normal adult men: implications for the diagnosis of pulmonary hypertension | Q63321244 | ||
Estimation of pulmonary artery pressure by Doppler echocardiography in normal subjects made hypoxic | Q68597263 | ||
Comparison of several noninvasive methods for estimation of pulmonary artery pressure | Q69451487 | ||
Chamber for controlling end-tidal gas tensions over sustained periods in humans | Q72298443 | ||
Time course of the human pulmonary vascular response to 8 hours of isocapnic hypoxia | Q73757516 | ||
Effects of desferrioxamine on serum erythropoietin and ventilatory sensitivity to hypoxia in humans | Q74113289 | ||
Erythropoietic effect of cobalt in patients with or without anemia | Q80321871 | ||
The influence of short periods of induced acute anoxia upon pulmonary artery pressures in man | Q83251337 | ||
Unexplained iron deficiency in idiopathic and heritable pulmonary arterial hypertension | Q83378571 | ||
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Iron deficiency and raised hepcidin in idiopathic pulmonary arterial hypertension: clinical prevalence, outcomes, and mechanistic insights. | Q50530002 | ||
IRP1 regulates erythropoiesis and systemic iron homeostasis by controlling HIF2α mRNA translation. | Q50897468 | ||
The clinical significance of anaemia and disturbed iron homeostasis in chronic respiratory failure. | Q51132510 | ||
Iron deficiency is common in idiopathic pulmonary arterial hypertension | Q51749929 | ||
Echocardiographic and invasive measurements of pulmonary artery pressure correlate closely at high altitude. | Q52073422 | ||
Noninvasive estimation of right ventricular systolic pressure by Doppler ultrasound in patients with tricuspid regurgitation. | Q52431887 | ||
Two temporal components within the human pulmonary vascular response to approximately 2 h of isocapnic hypoxia. | Q53631134 | ||
Operation Everest II: elevated high-altitude pulmonary resistance unresponsive to oxygen. | Q54402140 | ||
Observations on the Pulmonary Arterial Blood Pressure in the Cat | Q55922805 | ||
Regulation of hepcidin expression at high altitude | Q57099354 | ||
Iron-dependent regulation of the divalent metal ion transporter | Q28210422 | ||
The role of the iron responsive element in the control of ferroportin1/IREG1/MTP1 gene expression | Q28211300 | ||
Mutation of von Hippel-Lindau tumour suppressor and human cardiopulmonary physiology | Q28218986 | ||
Identification of erythroferrone as an erythroid regulator of iron metabolism | Q28240988 | ||
Expanding chemical biology of 2-oxoglutarate oxygenases | Q28268841 | ||
Genetic evidence for high-altitude adaptation in Tibet | Q28282435 | ||
Iron-regulatory proteins limit hypoxia-inducible factor-2alpha expression in iron deficiency | Q28297161 | ||
Identification of the iron-responsive element for the translational regulation of human ferritin mRNA | Q28302958 | ||
Impaired physiological responses to chronic hypoxia in mice partially deficient for hypoxia-inducible factor 1alpha | Q28508120 | ||
Purification and characterization of hypoxia-inducible factor 1 | Q28678375 | ||
Oxygen sensing by metazoans: the central role of the HIF hydroxylase pathway | Q29617805 | ||
Oxygen sensing by HIF hydroxylases | Q29617806 | ||
Hypoxic pulmonary vasoconstriction does not contribute to pulmonary blood flow heterogeneity in normoxia in normal supine humans. | Q33389768 | ||
Point: Hypobaric hypoxia induces different physiological responses from normobaric hypoxia | Q33453128 | ||
Extent to which pulmonary vascular responses to PCO2 and PO2 play a functional role within the healthy human lung | Q33841152 | ||
Beneficial effects of long-term intravenous iron therapy with ferric carboxymaltose in patients with symptomatic heart failure and iron deficiency†. | Q34041875 | ||
Disruption of oxygen homeostasis underlies congenital Chuvash polycythemia | Q34157665 | ||
Genetic evidence of paleolithic colonization and neolithic expansion of modern humans on the tibetan plateau | Q34345228 | ||
A genetic mechanism for Tibetan high-altitude adaptation | Q34433853 | ||
Inhibition of prolyl hydroxylases increases erythropoietin production in ESRD. | Q34457199 | ||
Variations in alveolar partial pressure for carbon dioxide and oxygen have additive not synergistic acute effects on human pulmonary vasoconstriction | Q34917895 | ||
Inhaled nitric oxide alters the distribution of blood flow in the healthy human lung, suggesting active hypoxic pulmonary vasoconstriction in normoxia | Q35034886 | ||
Contrasting effects of ascorbate and iron on the pulmonary vascular response to hypoxia in humans | Q35094143 | ||
Anoxia and human pulmonary vascular resistance | Q35187284 | ||
Clinical demonstration of efficiency and reversibility of hypoxic pulmonary vasoconstriction in a patient presenting with unilateral incomplete bronchial occlusion | Q35412335 | ||
HIF-1: an oxygen and metal responsive transcription factor | Q35630605 | ||
Multiple factors affecting cellular redox status and energy metabolism modulate hypoxia-inducible factor prolyl hydroxylase activity in vivo and in vitro | Q35641801 | ||
The long history of iron in the Universe and in health and disease | Q35672646 | ||
A cross-sectional study of the prevalence and associations of iron deficiency in a cohort of patients with chronic obstructive pulmonary disease | Q35844059 | ||
Physiological aspects of high-altitude pulmonary edema | Q36036151 | ||
Heterogeneous pulmonary blood flow in response to hypoxia: a risk factor for high altitude pulmonary edema? | Q36353236 | ||
Deletion of iron regulatory protein 1 causes polycythemia and pulmonary hypertension in mice through translational derepression of HIF2α. | Q36602744 | ||
Determinants of ventilation and pulmonary artery pressure during early acclimatization to hypoxia in humans | Q36632620 | ||
Control of erythropoiesis in humans during prolonged exposure to the altitude of 6,542 m. | Q36747675 | ||
Supplementation of iron in pulmonary hypertension: Rationale and design of a phase II clinical trial in idiopathic pulmonary arterial hypertension | Q36810774 | ||
Nutritional iron deficiency | Q36908053 | ||
Erythrocytosis and pulmonary hypertension in a mouse model of human HIF2A gain of function mutation | Q36928937 | ||
The increase in pulmonary arterial pressure caused by hypoxia depends on iron status | Q37127689 | ||
Age-associated increases in pulmonary artery systolic pressure in the general population | Q37366030 | ||
Iron deficiency modifies gene expression variation induced by augmented hypoxia sensing | Q37366148 | ||
Iron homeostasis and its interaction with prolyl hydroxylases | Q37570491 | ||
Therapeutic manipulation of the HIF hydroxylases | Q37597176 | ||
Iron sequestration and anemia of inflammation | Q37604592 | ||
Anemia and iron deficiency in COPD patients: prevalence and the effects of correction of the anemia with erythropoiesis stimulating agents and intravenous iron | Q37623876 | ||
Tibetans living at sea level have a hyporesponsive hypoxia-inducible factor system and blunted physiological responses to hypoxia | Q37679345 | ||
HIF and pulmonary vascular responses to hypoxia | Q37679350 | ||
Human adaptation to the hypoxia of high altitude: the Tibetan paradigm from the pregenomic to the postgenomic era. | Q37679370 | ||
The HIF Pathway and Erythrocytosis | Q37799606 | ||
Peopling the Tibetan plateau: insights from archaeology | Q37896078 | ||
Oxygen sensing, homeostasis, and disease | Q37914865 | ||
The transforming growth factor-β-bone morphogenetic protein type signalling pathway in pulmonary vascular homeostasis and disease | Q38104321 | ||
Desferrioxamine induces erythropoietin gene expression and hypoxia-inducible factor 1 DNA-binding activity: implications for models of hypoxia signal transduction | Q38313423 | ||
Effects of iron supplementation and depletion on hypoxic pulmonary hypertension: two randomized controlled trials | Q38378487 | ||
Adaptation of iron requirement to hypoxic conditions at high altitude | Q38548790 | ||
The pulmonary vasculature--lessons from Tibetans and from rare diseases of oxygen sensing | Q38635365 | ||
A prediction-correction scheme for forcing alveolar gases along certain time courses. | Q39353254 | ||
Heterozygous deficiency of hypoxia-inducible factor-2alpha protects mice against pulmonary hypertension and right ventricular dysfunction during prolonged hypoxia | Q39752665 | ||
Iron homeostasis and pulmonary hypertension: iron deficiency leads to pulmonary vascular remodeling in the rat. | Q41231467 | ||
Course of Pulmonary Hemodynamics in Patients with Chronic Obstructive Pulmonary Disease | Q41551887 | ||
Increased hepcidin levels in high-altitude pulmonary edema | Q41590698 | ||
Hypoxia-inducible factor regulates hepcidin via erythropoietin-induced erythropoiesis | Q42147890 | ||
Carotid body hyperplasia and enhanced ventilatory responses to hypoxia in mice with heterozygous deficiency of PHD2. | Q43063832 | ||
Ferric carboxymaltose in patients with heart failure and iron deficiency | Q43240282 | ||
Desferrioxamine elevates pulmonary vascular resistance in humans: potential for involvement of HIF-1. | Q43996721 | ||
Ferric carboxymaltose improves exercise capacity and quality of life in patients with pulmonary arterial hypertension and iron deficiency: a pilot study | Q44327077 | ||
Oxidative stress and renal injury with intravenous iron in patients with chronic kidney disease | Q44900463 | ||
Adaptation of iron transport and metabolism to acute high-altitude hypoxia in mountaineers | Q45140568 | ||
Iron deficiency in chronic heart failure: an international pooled analysis | Q46257022 | ||
Separating the direct effect of hypoxia from the indirect effect of changes in cardiac output on the maximum pressure difference across the tricuspid valve in healthy humans | Q47766597 | ||
Continuous wave Doppler determination of right ventricular pressure: a simultaneous Doppler-catheterization study in 127 patients | Q47914412 | ||
Iron deficiency defined as depleted iron stores accompanied by unmet cellular iron requirements identifies patients at the highest risk of death after an episode of acute heart failure | Q48716818 | ||
P275 | copyright license | Creative Commons Attribution | Q6905323 |
P6216 | copyright status | copyrighted | Q50423863 |
P433 | issue | 12 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | hypoxia | Q105688 |
inorganic compound | Q190065 | ||
oxygen consumption | Q70339049 | ||
P5008 | on focus list of Wikimedia project | ScienceSource | Q55439927 |
P304 | page(s) | 1421-1431 | |
P577 | publication date | 2015-06-11 | |
2015-12-15 | |||
P1433 | published in | Journal of Applied Physiology | Q1091719 |
P1476 | title | Iron, oxygen, and the pulmonary circulation | |
P478 | volume | 119 |
Q38548790 | Adaptation of iron requirement to hypoxic conditions at high altitude |
Q36951774 | Clinical iron deficiency disturbs normal human responses to hypoxia |
Q38975559 | Exaggerated pulmonary vascular response to acute hypoxia in older men. |
Q89941197 | High geographic prevalence of pulmonary artery hypertension: associations with ethnicity, drug use, and altitude |
Q64230500 | Iron Homeostasis in the Lungs-A Balance between Health and Disease |
Q46513546 | Pollution Control Meets Sustainability: Structure-Activity Studies on New Iron Oxide-Based CO Oxidation Catalysts. |
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