Mass cytometry as a platform for the discovery of cellular biomarkers to guide effective rheumatic disease therapy

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Mass cytometry as a platform for the discovery of cellular biomarkers to guide effective rheumatic disease therapy is …
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scholarly articleQ13442814
review articleQ7318358

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P6179Dimensions Publication ID1008953903
P356DOI10.1186/S13075-015-0644-Z
P3181OpenCitations bibliographic resource ID3345597
P932PMC publication ID4436107
P698PubMed publication ID25981462
P5875ResearchGate publication ID276850955

P50authorNitya NairQ57865288
Garry P. NolanQ89180933
Holden T. MaeckerQ93173386
P2093author name stringShih-Yu Chen
Mark Genovese
C Garrison Fathman
Chan C Whiting
Henrik E Mei
Matthew Hale
P2860cites workSingle-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuumQ24594356
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Cytometry by time-of-flight shows combinatorial cytokine expression and virus-specific cell niches within a continuum of CD8+ T cell phenotypesQ30543634
Combinatorial tetramer staining and mass cytometry analysis facilitate T-cell epitope mapping and characterization.Q30550855
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viSNE enables visualization of high dimensional single-cell data and reveals phenotypic heterogeneity of leukemiaQ30628090
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Automated identification of stratifying signatures in cellular subpopulationsQ33854094
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Multiplexed ion beam imaging of human breast tumorsQ33949706
A gene-environment interaction between smoking and shared epitope genes in HLA-DR provides a high risk of seropositive rheumatoid arthritisQ33982255
Extracting a cellular hierarchy from high-dimensional cytometry data with SPADEQ34037159
From single cells to deep phenotypes in cancerQ34287095
Multiplexed mass cytometry profiling of cellular states perturbed by small-molecule regulatorsQ34294698
The number of elevated cytokines and chemokines in preclinical seropositive rheumatoid arthritis predicts time to diagnosis in an age-dependent mannerQ34307377
CytoSPADE: high-performance analysis and visualization of high-dimensional cytometry dataQ34332830
Adalimumab, a fully human anti-tumor necrosis factor alpha monoclonal antibody, for the treatment of rheumatoid arthritis in patients taking concomitant methotrexate: the ARMADA trialQ34530459
Mass cytometry: technique for real time single cell multitarget immunoassay based on inductively coupled plasma time-of-flight mass spectrometryQ34992218
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Treatment with rituximab affects both the cellular and the humoral arm of the immune system in patients with SLE.Q51978495
Cytokine production by synovial T cells in rheumatoid arthritisQ77745456
Sialic acid-binding Ig-like lectin 1 expression in inflammatory and resident monocytes is a potential biomarker for monitoring disease activity and success of therapy in systemic lupus erythematosusQ81000909
Expansion of a unique macrophage subset in rheumatoid arthritis synovial lining layerQ81828653
CD11c as a transcriptional biomarker to predict response to anti-TNF monotherapy with adalimumab in patients with rheumatoid arthritisQ82332974
Tissue factor expression in rheumatoid synovium: a potential role in pannus invasion of rheumatoid arthritisQ86382359
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A platinum-based covalent viability reagent for single-cell mass cytometry.Q37257000
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Single-cell mass cytometry for analysis of immune system functional statesQ37330089
Automatic Classification of Cellular Expression by Nonlinear Stochastic Embedding (ACCENSE).Q37475009
The vasculature in rheumatoid arthritis: cause or consequence?Q37534978
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B cells in the pathogenesis and treatment of rheumatoid arthritisQ37678888
ACPA-positive and ACPA-negative rheumatoid arthritis differ in their requirements for combination DMARDs and corticosteroids: secondary analysis of a randomized controlled trialQ37691090
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Review of treatment response in rheumatoid arthritis: assessment of heterogeneityQ37832733
Abatacept mechanism of action: concordance with its clinical profileQ37959086
New biomarkers in rheumatoid arthritisQ38057572
Cytokine-producing B cells as regulators of pathogenic and protective immune responsesQ38068692
Synovial tissue macrophages: a sensitive biomarker for response to treatment in patients with rheumatoid arthritisQ39701973
Steady-state generation of mucosal IgA+ plasmablasts is not abrogated by B-cell depletion therapy with rituximabQ42911721
Serologic changes following B lymphocyte depletion therapy for rheumatoid arthritisQ44541019
Antigen microarray profiling of autoantibodies in rheumatoid arthritis.Q46107435
P275copyright licenseCreative Commons AttributionQ6905323
P6216copyright statuscopyrightedQ50423863
P407language of work or nameEnglishQ1860
P921main subjectrheumatoid arthritisQ187255
rheumatismQ684924
biomarkerQ864574
biomedical investigative techniqueQ66648976
P5008on focus list of Wikimedia projectScienceSourceQ55439927
P304page(s)127
P577publication date2015-05-18
P1433published inArthritis Research and TherapyQ15757229
P1476titleMass cytometry as a platform for the discovery of cellular biomarkers to guide effective rheumatic disease therapy
P478volume17

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