| review article | Q7318358 |
| scholarly article | Q13442814 |
| P50 | author | Neil Vargesson | Q43166035 |
| P2860 | cites work | Molecular analysis of regulative events in the developing chick limb. | Q50744174 |
| Teratogen update: clinical aspects of thalidomide embryopathy--a continuing preoccupation. | Q52082254 | ||
| Evaluation of the developmental toxicity of thalidomide using frog embryo teratogenesis assay-xenopus (FETAX): biotransformation and detoxification. | Q52172341 | ||
| Vascular dysgenesis associated with skeletal dysplasia of the lower limb. | Q52297044 | ||
| Smad7 misexpression during embryonic angiogenesis causes vascular dilation and malformations independently of vascular smooth muscle cell function. | Q52544971 | ||
| Thalidomide-induced angiopoietin 2, Notch1 and Dll4 downregulation under hypoxic condition in tissues with gastrointestinal vascular malformation and human umbilical vein endothelial cells. | Q53083368 | ||
| Some congenital abnormalities: Possibly due to embryonic peripheral neuropathy | Q54192419 | ||
| Inhibition of endothelial Slit2/Robo1 signaling by thalidomide restrains angiogenesis by blocking the PI3K/Akt pathway. | Q54314849 | ||
| History, heresy and radiology in scientific discovery | Q43269688 | ||
| Racemates revisited: heterochiral assemblies and the example of DL-thalidomide. | Q43478203 | ||
| Refractive evaluation in thalidomide embryopathy | Q43514393 | ||
| 5'-OH-thalidomide, a metabolite of thalidomide, inhibits angiogenesis. | Q43863331 | ||
| Offspring of male and female parents with thalidomide embryopathy: birth defects and functional anomalies | Q44124753 | ||
| Misregulation of gene expression in the redox-sensitive NF-kappab-dependent limb outgrowth pathway by thalidomide | Q44146012 | ||
| An in ovo chicken model to study the systemic and localized teratogenic effects of valproic acid | Q44157475 | ||
| Antiangiogenic activity of N-substituted and tetrafluorinated thalidomide analogues | Q44480741 | ||
| A novel hypothesis for thalidomide-induced limb teratogenesis: redox misregulation of the NF-kappaB pathway | Q44720745 | ||
| Thalidomide-induced antiangiogenic action is mediated by ceramide through depletion of VEGF receptors, and is antagonized by sphingosine-1-phosphate | Q45291431 | ||
| Zebrafish cul4a, but not cul4b, modulates cardiac and forelimb development by upregulating tbx5a expression. | Q47073820 | ||
| Thalidomide (5HPP-33) suppresses microtubule dynamics and depolymerizes the microtubule network by binding at the vinblastine binding site on tubulin | Q47989598 | ||
| Thalidomide: lack of mutagenic activity across phyla and genetic endpoints | Q50132461 | ||
| Identification of thalidomide-specific transcriptomics and proteomics signatures during differentiation of human embryonic stem cells | Q34406463 | ||
| Roberts syndrome is caused by mutations in ESCO2, a human homolog of yeast ECO1 that is essential for the establishment of sister chromatid cohesion | Q34410361 | ||
| Thalidomide, a current teratogen in South America | Q34421312 | ||
| Thalidomide and congenital abnormalities | Q34540171 | ||
| A study of the German outbreak of phocomelia. The thalidomide syndrome. | Q34540202 | ||
| Teratogenic effects of thalidomide: molecular mechanisms | Q34660391 | ||
| Clinical observations on the thalidomide syndrome | Q34982059 | ||
| Vascularization of the developing chick limb bud: role of the TGFbeta signalling pathway | Q35066911 | ||
| Congenital Ear Abnormalities Due to Thalidomide. | Q35854105 | ||
| Nitric oxide rescues thalidomide mediated teratogenicity | Q36247884 | ||
| Thalidomide induces limb anomalies by PTEN stabilization, Akt suppression, and stimulation of caspase-dependent cell death | Q36421389 | ||
| Thalidomide use in the US : experience with pregnancy testing in the S.T.E.P.S. programme | Q36433995 | ||
| Disruption of the cereblon gene enhances hepatic AMPK activity and prevents high-fat diet-induced obesity and insulin resistance in mice. | Q36867631 | ||
| What can we learn from the thalidomide experience: an ophthalmologic perspective | Q37019889 | ||
| Amputation-induced reactive oxygen species are required for successful Xenopus tadpole tail regeneration | Q37057861 | ||
| Endothelial Notch activity promotes angiogenesis and osteogenesis in bone | Q37091548 | ||
| OCULAR DEFECTS IN THALIDOMIDE BABIES. | Q37329416 | ||
| Oxidative stress in developmental origins of disease: teratogenesis, neurodevelopmental deficits, and cancer | Q37363562 | ||
| Prenatal exposure to thalidomide, altered vasculogenesis, and CNS malformations | Q37509237 | ||
| Thalidomide and misoprostol: Ophthalmologic manifestations and associations both expected and unexpected | Q37565355 | ||
| Consistent arterial abnormalities associated with a variety of congenital malformations of the human lower limb | Q37717547 | ||
| Apoptosis induction by thalidomide: critical for limb teratogenicity but therapeutic potential in idiopathic pulmonary fibrosis? | Q37801385 | ||
| Redox control of teratogenesis | Q38054295 | ||
| Recognition of the phenotype of thalidomide embryopathy in countries endemic for leprosy: new cases and review of the main dysmorphological findings | Q38085445 | ||
| Effect of maternal diabetes on the embryo, fetus, and children: congenital anomalies, genetic and epigenetic changes and developmental outcomes | Q38382091 | ||
| Fetal malformations and early embryonic gene expression response in cynomolgus monkeys maternally exposed to thalidomide | Q38508987 | ||
| Free radical-mediated oxidative DNA damage in the mechanism of thalidomide teratogenicity | Q39225712 | ||
| A short history of thalidomide embryopathy | Q39562228 | ||
| Proposed mechanisms of action in thalidomide embryopathy | Q39562235 | ||
| The thalidomide syndrome: risks of exposure and spectrum of malformations | Q39745283 | ||
| Thalidomide induces limb deformities by perturbing the Bmp/Dkk1/Wnt signaling pathway | Q40174117 | ||
| S.T.E.P.S.: a comprehensive program for controlling and monitoring access to thalidomide | Q40816692 | ||
| Evalulation of thalidomide children | Q41514640 | ||
| Chemical structure and teratogenic properties. IV. An outline of a chemical hypothesis for the teratogenic action of thalidomide | Q41515393 | ||
| Coupling of angiogenesis and osteogenesis by a specific vessel subtype in bone | Q41881171 | ||
| The effect of thalidomide in chicken embryos | Q41994803 | ||
| Embryotoxic effects of thalidomide-derivatives in the non-human primate Callithrix jacchus. I. Effects of 3-(1,3-dihydro-1-oxo-2H-isoindol-2-yl)-2,6-dioxopiperidine (EM12) on skeletal development | Q42213599 | ||
| Effects of thalidomide and related metabolites in a mouse corneal model of neovascularization | Q42547622 | ||
| Thalidomide exerts its inhibitory action on tumor necrosis factor alpha by enhancing mRNA degradation | Q42941758 | ||
| A case of Roberts syndrome described in 1737. | Q43075202 | ||
| Identification of a primary target of thalidomide teratogenicity | Q24302178 | ||
| Homozygous WNT3 mutation causes tetra-amelia in a large consanguineous family | Q24307763 | ||
| A mutation in a novel ATP-dependent Lon protease gene in a kindred with mild mental retardation | Q24532087 | ||
| Inactivating mutations in ESCO2 cause SC phocomelia and Roberts syndrome: no phenotype-genotype correlation | Q24538533 | ||
| Thalidomide is an inhibitor of angiogenesis | Q24563363 | ||
| Pomalidomide is nonteratogenic in chicken and zebrafish embryos and nonneurotoxic in vitro | Q24634078 | ||
| Thalidomide induces limb defects by preventing angiogenic outgrowth during early limb formation | Q24653215 | ||
| Mutations at the SALL4 locus on chromosome 20 result in a range of clinically overlapping phenotypes, including Okihiro syndrome, Holt-Oram syndrome, acro-renal-ocular syndrome, and patients previously reported to represent thalidomide embryopathy | Q24676719 | ||
| Structure of the DDB1–CRBN E3 ubiquitin ligase in complex with thalidomide | Q27684738 | ||
| Structure of the human Cereblon-DDB1-lenalidomide complex reveals basis for responsiveness to thalidomide analogs | Q27694755 | ||
| Thalidomide mimics uridine binding to an aromatic cage in cereblon | Q27696255 | ||
| Autism associated with conditions characterized by developmental errors in early embryogenesis: a mini review | Q28238209 | ||
| Mutations in SALL4 in malformed father and daughter postulated previously due to reflect mutagenesis by thalidomide | Q28278915 | ||
| The myeloma drug lenalidomide promotes the cereblon-dependent destruction of Ikaros proteins | Q28303081 | ||
| Lenalidomide causes selective degradation of IKZF1 and IKZF3 in multiple myeloma cells | Q28303091 | ||
| Defects and Disabilities of Thalidomide Children | Q28363637 | ||
| Transcriptomic characterization of C57BL/6 mouse embryonic stem cell differentiation and its modulation by developmental toxicants | Q28543170 | ||
| Genetic evidence that FGFs have an instructive role in limb proximal-distal patterning | Q28584721 | ||
| The non-redundant function of cohesin acetyltransferase Esco2: some answers and new questions | Q29347246 | ||
| Thalidomide attenuates nitric oxide mediated angiogenesis by blocking migration of endothelial cells | Q33238514 | ||
| Thalidomide-induced limb defects: resolving a 50-year-old puzzle | Q33348200 | ||
| Thalidomide attenuates nitric oxide-driven angiogenesis by interacting with soluble guanylyl cyclase | Q33569519 | ||
| Recognition of thalidomide defects | Q33594538 | ||
| Teratogen update: thalidomide: a review, with a focus on ocular findings and new potential uses | Q33753486 | ||
| Thalidomide is not a human mutagen | Q33813079 | ||
| Hypothesis: thalidomide embryopathy-proposed mechanism of action | Q33831075 | ||
| Mechanism of action in thalidomide teratogenesis | Q33900903 | ||
| A zebrafish model of Roberts syndrome reveals that Esco2 depletion interferes with development by disrupting the cell cycle | Q33921221 | ||
| Thalidomide stimulates vessel maturation and reduces epistaxis in individuals with hereditary hemorrhagic telangiectasia | Q34021937 | ||
| Genome-wide analysis of gene expression during Xenopus tropicalis tadpole tail regeneration | Q34074952 | ||
| Thalidomide | Q56091164 | ||
| New cases of thalidomide embryopathy in Brazil | Q56786143 | ||
| Thalidomide Embryopathy: An Enigmatic Challenge | Q57129133 | ||
| Linear growth of children with limb deformities following exposure to thalidomide in utero | Q67706025 | ||
| Studies of the etiology of thalidomide dysmorphogenesis | Q67800456 | ||
| Thalidomide update: regulatory aspects | Q68034109 | ||
| The effect of thalidomide intake during 113 human pregnancies | Q69598612 | ||
| Dissimilar effects of thalidomide in dizygotic twins | Q70668863 | ||
| Thalidomide victims in a rehabilitation center | Q70768158 | ||
| Clinical studies on teenage Brazilian victims of thalidomide | Q71139004 | ||
| Inhibition of thalidomide teratogenicity by acetylsalicylic acid: evidence for prostaglandin H synthase-catalyzed bioactivation of thalidomide to a teratogenic reactive intermediate | Q71152786 | ||
| Congenital short femur. Clinical, genetic and epidemiological comparison of the naturally occurring condition with that caused by thalidomide | Q71302693 | ||
| The sensitive phase in thalidomide embryopathy | Q72662637 | ||
| Teratogenetic properties of thalidomide | Q72722868 | ||
| Thalidomide induced malformations--a radiological survey | Q76471279 | ||
| Shoulder joint replacement for osteoarthrosis in association with thalidomide-induced phocomelia | Q77957714 | ||
| THALIDOMIDE IN THE TREATMENT OF LEPRA REACTIONS | Q78373559 | ||
| Thalidomide and malformations in Liverpool | Q79421169 | ||
| Thalidomide and congenital abnormalities | Q79422584 | ||
| The incidence of limb and ear defects since the withdrawal of thalidomide | Q79671102 | ||
| Embryopathic effects of thalidomide and its hydrolysis products in rabbit embryo culture: evidence for a prostaglandin H synthase (PHS)-dependent, reactive oxygen species (ROS)-mediated mechanism | Q83896327 | ||
| Teratogenic effects of thalidomide and related substances | Q94295685 | ||
| P275 | copyright license | Creative Commons Attribution | Q6905323 |
| P6216 | copyright status | copyrighted | Q50423863 |
| P433 | issue | 2 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | heterocyclic compound | Q193430 |
| thalidomide | Q203174 | ||
| carboxylic acid | Q134856 | ||
| P304 | page(s) | 140-56 | |
| P577 | publication date | 2015-06-01 | |
| P1433 | published in | Birth Defects Research Part C: Embryo Today Reviews | Q15757886 |
| P1476 | title | Thalidomide-induced teratogenesis: history and mechanisms | |
| P478 | volume | 105 |
| Q54632784 | "The legacy of thalidomide" - A multidisciplinary meeting held at the University of York, United Kingdom, on September 30, 2016. |
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