Endocrine-disrupting Chemicals: Review of Toxicological Mechanisms Using Molecular Pathway Analysis

scientific article

Endocrine-disrupting Chemicals: Review of Toxicological Mechanisms Using Molecular Pathway Analysis is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.15430/JCP.2015.20.1.12
P932PMC publication ID4384711
P698PubMed publication ID25853100

P2093author name stringHye Lim Kim
Young Rok Seo
Jong-Il Weon
Oneyeol Yang
P2860cites workConserved amino acids in the ligand-binding and tau(i) domains of the peroxisome proliferator-activated receptor alpha are necessary for heterodimerization with RXRQ22009158
Genetic variation in ICF syndrome: evidence for genetic heterogeneityQ24290581
The Polycomb group protein EZH2 directly controls DNA methylationQ24299020
Lef-1 isoforms regulate different target genes and reduce cellular adhesionQ24321215
The human LEF-1 gene contains a promoter preferentially active in lymphocytes and encodes multiple isoforms derived from alternative splicingQ24516566
Exposure to phthalates and breast cancer risk in northern MexicoQ24594495
How strong is the evidence of a link between environmental chemicals and adverse effects on human reproductive health?Q24600244
Prenatal exposure to the environmental obesogen tributyltin predisposes multipotent stem cells to become adipocytesQ24623235
Environmental phthalate exposure in relation to reproductive outcomes and other health endpoints in humansQ24641810
Minireview: the case for obesogensQ24641886
Endocrine disrupters as obesogensQ24647272
Endocrine-disrupting chemicals: an Endocrine Society scientific statementQ24651457
Human cyclin E, a nuclear protein essential for the G1-to-S phase transitionQ24652527
Regulation of peroxisome proliferator-activated receptor alpha-induced transactivation by the nuclear orphan receptor TAK1/TR4Q28115776
Levels of di-(2-ethylhexyl)phthalate and total phthalate esters in milk, cream, butter and cheeseQ28238576
Environmental obesogens: organotins and endocrine disruption via nuclear receptor signalingQ28239680
Human and rat peroxisome proliferator activated receptors (PPARs) demonstrate similar tissue distribution but different responsiveness to PPAR activatorsQ28241939
A nonsense mutation in the first transmembrane domain of connexin 43 underlies autosomal recessive oculodentodigital syndromeQ28249865
Organotin compounds promote adipocyte differentiation as agonists of the peroxisome proliferator-activated receptor gamma/retinoid X receptor pathwayQ28299413
Polychlorinated biphenyl-77 induces adipocyte differentiation and proinflammatory adipokines and promotes obesity and atherosclerosisQ28384652
Toxicogenomic and phenotypic analyses of bisphenol-A early-life exposure toxicity in zebrafishQ28478402
n-Butyl benzyl phthalate promotes breast cancer progression by inducing expression of lymphoid enhancer factor 1Q28482126
Di(n-Butyl) Phthalate Impairs Cholesterol Transport and Steroidogenesis in the Fetal Rat Testis through a Rapid and Reversible MechanismQ28565197
Stimulation of adipogenesis in fibroblasts by PPAR gamma 2, a lipid-activated transcription factorQ29547912
Fat and beyond: the diverse biology of PPARgammaQ29615416
Current status of cadmium as an environmental health problemQ29617566
Exploring interactions of endocrine-disrupting compounds with different conformations of the human estrogen receptor alpha ligand binding domain: a molecular docking study.Q30372717
Species-specific dibutyl phthalate fetal testis endocrine disruption correlates with inhibition of SREBP2-dependent gene expression pathwaysQ30427695
Time-dependent and compartment-specific effects of in utero exposure to Di(n-butyl) phthalate on gene/protein expression in the fetal rat testis as revealed by transcription profiling and laser capture microdissectionQ33279718
Cadmium-induced testicular injuryQ33584117
Bisphenol A: Perinatal exposure and body weightQ33635524
Gene expression profiling analysis of bisphenol A-induced perturbation in biological processes in ER-negative HEK293 cellsQ33717194
Cadmium mimics the in vivo effects of estrogen in the uterus and mammary gland.Q33967143
Developmental triclosan exposure decreases maternal and neonatal thyroxine in ratsQ34024337
Mono-(2-ethylhexyl) phthalate directly alters the expression of Leydig cell genes and CYP17 lyase activity in cultured rat fetal testisQ34075536
Identification of novel low-dose bisphenol a targets in human foreskin fibroblast cells derived from hypospadias patientsQ34264912
Urinary biomarkers for phthalates associated with asthma in Norwegian childrenQ34312667
Polybrominated diphenyl ethers contamination of United States foodQ34367698
The adjuvant effect induced by di-(2-ethylhexyl) phthalate (DEHP) is mediated through oxidative stress in a mouse model of asthmaQ46876011
Molecular responses to xenoestrogens: mechanistic insights from toxicogenomicsQ48342847
Are cadmium effects on plasma gonadotropins, prolactin, ACTH, GH and TSH levels, dose-dependent?Q48394215
Serum concentrations of organochlorine compounds and endometrial cancer risk (United States).Q52566373
Xenoestrogen interaction with human sex hormone-binding globulin (hSHBG).Q53726166
Endometrial effects of long-term treatment with phytoestrogens: a randomized, double-blind, placebo-controlled studyQ61852148
Cancer incidence in a population accidentally exposed to 2,3,7,8-tetrachlorodibenzo-para-dioxinQ70481796
Synergistic activation of estrogen receptor-mediated transcription by estradiol and protein kinase activatorsQ72078757
Novel molecular targets associated with testicular dysgenesis induced by gestational exposure to diethylhexyl phthalate in the rat: a role for estradiolQ87414895
DNMT3B mutations and DNA methylation defect define two types of ICF syndrome.Q34373710
Bisphenol A and human chronic diseases: current evidences, possible mechanisms, and future perspectivesQ34395192
Metalloestrogens: an emerging class of inorganic xenoestrogens with potential to add to the oestrogenic burden of the human breastQ34496144
The endocrine disruptor monoethyl-hexyl-phthalate is a selective peroxisome proliferator-activated receptor gamma modulator that promotes adipogenesisQ34623928
An alkylphenol mix promotes seminoma derived cell proliferation through an ERalpha36-mediated mechanismQ34692315
Impact of endocrine disruptor chemicals in gynaecology.Q34723481
Baby care products: possible sources of infant phthalate exposureQ34745000
Nonylphenol in the environment: a critical review on occurrence, fate, toxicity and treatment in wastewaters.Q34751741
PPAR-mediated activity of phthalates: A link to the obesity epidemic?Q34980414
miRNA regulation of cytotoxic effects in mouse Sertoli cells exposed to nonylphenolQ35389756
Endocrine disruption by cadmium, a common environmental toxicant with paradoxical effects on reproduction.Q35750846
Mono-(2-ethylhexyl) phthalate (MEHP) promotes invasion and migration of human testicular embryonal carcinoma cellsQ36000661
Effects of endocrine disruptors on developmental and reproductive functions.Q36074414
Phthalate exposure changes the metabolic profile of cardiac muscle cells.Q36229241
Global gene expression analysis reveals pathway differences between teratogenic and non-teratogenic exposure concentrations of bisphenol A and 17β-estradiol in embryonic zebrafishQ36950029
Di-(2 ethylhexyl) phthalate and flutamide alter gene expression in the testis of immature male rats.Q37384183
Alkylphenols in marine environments: distribution monitoring strategies and detection considerationsQ37499155
Sample clean-up by sol-gel immunoaffinity chromatography for the determination of bisphenol A in food and urineQ37922945
Celery oil modulates DEHP-induced reproductive toxicity in male ratsQ39062845
Oxidative stress and phthalate-induced down-regulation of steroidogenesis in MA-10 Leydig cellsQ39106548
Structure-dependent activation of peroxisome proliferator-activated receptor (PPAR) gamma by organotin compoundsQ39842587
A functional peroxisome proliferator-activated receptor-gamma ligand-binding domain is not required for adipogenesisQ39962094
Cadmium induces mitogenic signaling in breast cancer cell by an ERalpha-dependent mechanismQ40204595
Differential effects of cadmium on the gene expression of seven-transmembrane-spanning receptors and GAPDH in the rat testisQ40267054
Genistein represses telomerase activity via both transcriptional and posttranslational mechanisms in human prostate cancer cellsQ40314340
Cadmium stimulates transcription of the cytochrome p450 side chain cleavage gene in genetically modified stable porcine granulosa cellsQ40637834
Altered gene profiles in fetal rat testes after in utero exposure to di(n-butyl) phthalateQ40674915
Synergisms with mixtures of xenoestrogens: a reevaluation using the method of isobolesQ40995728
Inhibition of c-myc expression by phosphorothioate antisense oligonucleotide identifies a critical role for c-myc in the growth of human breast cancerQ41155996
Activation of kinase pathways in MCF-7 cells by 17beta-estradiol and structurally diverse estrogenic compoundsQ42170316
Identification of transcription factors and coactivators affected by dibutylphthalate interactions in fetal rat testesQ42713180
Bisphenol a accelerates terminal differentiation of 3T3-L1 cells into adipocytes through the phosphatidylinositol 3-kinase pathwayQ42819042
Potent inhibition of estrogen sulfotransferase by hydroxylated PCB metabolites: a novel pathway explaining the estrogenic activity of PCBsQ43502863
Effects of polybrominated diphenyl ethers (PBDEs) and polychlorinated biphenyls (PCBs) on thyroid hormone and vitamin A levels in rats and mice.Q43693618
Role of cadmium in the regulation of AR gene expression and activityQ43829594
Survey of bisphenol A and bisphenol F in canned foodsQ44134974
Quantitative Changes in Gene Expression in Fetal Rat Testes following Exposure to Di(n-butyl) PhthalateQ44406835
Cadmium exposure differentially modifies the circadian patterns of norepinephrine at the median eminence and plasma LH, FSH and testosterone levelsQ44672988
Mutations in GJA1 (connexin 43) are associated with non-syndromic autosomal recessive deafnessQ44884995
Dose-dependent alterations in gene expression and testosterone synthesis in the fetal testes of male rats exposed to di (n-butyl) phthalateQ44894574
Polybrominated diphenyl ethers as endocrine disruptors of adipocyte metabolismQ45130791
Differential steroidogenic gene expression in the fetal adrenal gland versus the testis and rapid and dynamic response of the fetal testis to di(n-butyl) phthalateQ46575149
Cadmium, lead, and thallium in mainstream tobacco smoke particulateQ46821784
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectpathway analysisQ25303877
P304page(s)12-24
P577publication date2015-03-01
P1433published inJournal of cancer preventionQ26841879
P1476titleEndocrine-disrupting Chemicals: Review of Toxicological Mechanisms Using Molecular Pathway Analysis
P478volume20

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cites work (P2860)
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