Nanostructured platforms for the sustained and local delivery of antibiotics in the treatment of osteomyelitis

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Nanostructured platforms for the sustained and local delivery of antibiotics in the treatment of osteomyelitis is …
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review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1615/CRITREVTHERDRUGCARRIERSYST.2014010920
P3181OpenCitations bibliographic resource ID590791
P932PMC publication ID4406243
P698PubMed publication ID25746204

P50authorVuk UskokovićQ37829335
P2093author name stringUskokovic V
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Bone regenerative properties of injectable PGLA-CaP composite with TGF-beta1 in a rat augmentation model.Q47921909
Cellular biocompatibility and stimulatory effects of calcium metaphosphate on osteoblastic differentiation of human bone marrow-derived stromal cellsQ47953342
Introduction of gelatin microspheres into an injectable calcium phosphate cementQ47981064
Sustainable release of vancomycin, gentamicin and lidocaine from novel electrospun sandwich-structured PLGA/collagen nanofibrous membranesQ48168635
Stimulation of cell proliferation by calcium and a calcimimetic compoundQ48632470
Effects of four types of hydroxyapatite nanoparticles with different nanocrystal morphologies and sizes on apoptosis in rat osteoblastsQ50263241
Luminescence variations in hydroxyapatites doped with Eu2+ and Eu3+ ionsQ50447199
Calcium phosphate-mediated gene delivery using simulated body fluid (SBF).Q50495786
An evaluation of plaster of Paris barriers used under various materials to repair furcation perforations (in vitro study).Q50516183
Magnesium, zinc, copper, manganese, and selenium levels in postmenopausal women with osteoporosis. Can magnesium play a key role in osteoporosis?Q50638668
Intrinsic magnetism and hyperthermia in bioactive Fe-doped hydroxyapatite.Q50790509
Preparation of porous apatite granules from calcium phosphate cement.Q50852997
Polylactide-polyglycolide antibiotic implantsQ36213851
Intrinsically superparamagnetic Fe-hydroxyapatite nanoparticles positively influence osteoblast-like cell behaviourQ36281568
Effect of silver content on the structure and antibacterial activity of silver-doped phosphate-based glasses.Q36313255
Biodegradable and bioactive porous polymer/inorganic composite scaffolds for bone tissue engineering.Q36407629
The circadian clock modulates enamel developmentQ36438704
Antimicrobial peptides: review of their application in musculoskeletal infectionsQ36465051
Nanoparticles of cobalt-substituted hydroxyapatite in regeneration of mandibular osteoporotic bonesQ36597932
Hydroxyapatite nanoparticle-containing scaffolds for the study of breast cancer bone metastasisQ36731717
Adverse events after recombinant human BMP2 in nonspinal orthopaedic proceduresQ36732299
Bone crystal sizes: a comparison of transmission electron microscopic and X-ray diffraction line width broadening techniquesQ36735082
Effect of calcium phosphate particle shape and size on their antibacterial and osteogenic activity in the delivery of antibiotics in vitro.Q36826117
The tumor microenvironment is a dominant force in multidrug resistance.Q36856829
Design Strategies for Fluorescent Biodegradable Polymeric BiomaterialsQ36864841
Collagen: finding a solution for the sourceQ36880083
Osteoblast and osteoclast differentiation in modeled microgravityQ36893362
Human bites in the classroom: incidence, treatment, and complicationsQ36901794
Osteoporosis - a current view of pharmacological prevention and treatmentQ36939677
Mesoporous materials for drug delivery.Q36939951
Radially branched deployment for more efficient cell transplantation at the scale of the human brain.Q37086202
Citrate-based Biodegradable Injectable hydrogel Composites for Orthopedic ApplicationsQ37109770
Bone morphogenetic proteins in tissue engineering: the road from laboratory to clinic, part II (BMP delivery).Q37126334
Adjunctive use of rifampin for the treatment of Staphylococcus aureus infections: a systematic review of the literatureQ37149727
Mini-review: Proactive biomaterials and bone tissue engineeringQ37216521
Development of aliphatic biodegradable photoluminescent polymers.Q37238799
The Important Role of Osteoblasts and Citrate Production in Bone Formation: "Osteoblast Citration" as a New Concept for an Old RelationshipQ37274467
SiO2 and ZnO dopants in three-dimensionally printed tricalcium phosphate bone tissue engineering scaffolds enhance osteogenesis and angiogenesis in vivoQ37301787
Calcium sulfate: Properties and clinical applicationsQ37331920
Osteopontin functionalization of hydroxyapatite nanoparticles in a PDLLA matrix promotes bone formation.Q41222986
Bioelectric potential gradients may initiate cell cycling: ELF and zeta potential gradients may mimic this effectQ41519426
In vitro and in vivo bactericidal activities of vancomycin dispersed in porous biodegradable poly(epsilon-caprolactone) microparticlesQ41816207
Formulation of functionalized PLGA-PEG nanoparticles for in vivo targeted drug deliveryQ41847599
A biodegradable antibiotic delivery system based on poly-(trimethylene carbonate) for the treatment of osteomyelitisQ41864671
Effect of hydroxyapatite on the physicochemical characteristics of a gentamicin-loaded monoolein gel intended to treat chronic osteomyelitisQ41931511
The drug release study of ceftriaxone from porous hydroxyapatite scaffoldsQ41989195
A new antibacterial carrier of hyaluronic acid gel.Q42034233
In vitro antibiotic release from poly(3-hydroxybutyrate-co-3-hydroxyvalerate) rodsQ42169329
Cross-linked acrylic hydrogel for the controlled delivery of hydrophobic drugs in cancer therapyQ42265900
Theoretical model to determine the effects of geometrical factors on the resorption of calcium phosphate bone substitutesQ42622238
A new, simple, green, and one-pot four-component synthesis of bare and poly(α,γ, L-glutamic acid)-capped silver nanoparticlesQ42648217
Toxicogenomic analysis of the particle dose- and size-response relationship of silica particles-induced toxicity in mice.Q42713878
Brucella osteomyelitis of the proximal tibia: a case reportQ42752200
Nano-sized calcium phosphate particles for periodontal gene therapyQ42798305
Osteoblast activity on carbonated hydroxyapatiteQ42799854
Sol-gel processed mupirocin silica microspheres loaded collagen scaffold: a synergistic bio-composite for wound healingQ42806937
Reduction of inflammatory reaction of poly(d,l-lactic-co-glycolic Acid) using demineralized bone particlesQ42815499
Phase composition control of calcium phosphate nanoparticles for tunable drug delivery kinetics and treatment of osteomyelitis. II. Antibacterial and osteoblastic responseQ42829153
A prospective, randomized clinical trial comparing an antibiotic-impregnated bioabsorbable bone substitute with standard antibiotic-impregnated cement beads in the treatment of chronic osteomyelitis and infected nonunionQ42958962
Teicoplanin-loaded borate bioactive glass implants for treating chronic bone infection in a rabbit tibia osteomyelitis modelQ43077573
Liposome combined porous beta-TCP scaffold: preparation, characterization, and anti-biofilm activityQ43080159
Treatment of osteomyelitis with teicoplanin-encapsulated biodegradable thermosensitive hydrogel nanoparticles.Q43104462
Microelectrode studies on the acid microenvironment beneath adherent macrophages and osteoclasts*1Q68325243
Rapid release of gentamicin from collagen sponge. In vitro comparison with plastic beadsQ68924484
Biomaterial-centered infection: microbial adhesion versus tissue integrationQ69249483
Gentamicin-impregnated polymethylmethacrylate beads compared with systemic antibiotic therapy in the treatment of chronic osteomyelitisQ70490112
In vivo assessment of methyl methacrylate metabolism and toxicityQ70952032
Osteo-articular complications of smallpox vaccinationQ71579554
Depot effects of various antibiotics mixed with Palacos resinsQ71612918
A self-setting TTCP-DCPD apatite cement for release of vancomycinQ71670511
Elution characteristics of vancomycin and tobramycin combined in acrylic bone-cementQ71952564
Zeolite a inhibits osteoclast‐mediated bone resorption in vitroQ71977669
Elution characteristics of gentamicin-PMMA beads after implantation in humansQ72072348
The effect of site of implantation and animal age on properties of polydioxanone pinsQ72496636
Polymeric calcium phosphate cements: setting reaction modifiersQ72753949
Staphylococcus aureus infection of mouse or human osteoblasts induces high levels of interleukin-6 and interleukin-12 productionQ73175508
Enhanced osteoclast-like cell functions on nanophase ceramicsQ73834400
Calcium hydroxide ameliorates tobramycin toxicity in cultured chick tibiaeQ73843941
Enhanced functions of osteoblasts on nanophase ceramicsQ74033988
Comparison of different types of ceramic hydroxyapatite for the chromatographic separation of plasmid DNA and a recombinant anti-rhesus D antibodyQ74414236
Synthesis of antibiotic-loaded interporous hydroxyapatite blocks by vacuum method and in vitro drug release testingQ74777183
[Mechanical failure of porous hydroxyapatite ceramics 7.5 years after implantation in the proximal tibial]Q76402766
Treatment of osteomyelitis by antibiotic impregnated porous hydroxyapatite blockQ77052383
Application of a rat osteomyelitis model to compare in vivo and in vitro the antibiotic efficacy against bacteria with high capacity to form biofilmsQ77364480
Chemical characterization of silicon-substituted hydroxyapatiteQ77975538
Raman microspectrometry studies of brushite cement: in vivo evolution in a sheep modelQ78160950
What is the normal rate of bone remodeling?Q80222494
Locally administered antibiotics for prophylaxis against surgical wound infection. An in vivo studyQ80249232
Performance and characterization of a nanophased porous hydroxyapatite for protein chromatographyQ80389880
Use of calcium-based demineralized bone matrix/allograft for nonunions and posttraumatic reconstruction of the appendicular skeleton: preliminary results and complicationsQ80532738
Low temperature direct 3D printed bioceramics and biocomposites as drug release matricesQ80681988
High-strength apatitic cement by modification with superplasticizersQ81109856
Importance of the surface area ratio on cytokines production by human monocytes in vitro induced by various hydroxyapatite particlesQ81109867
Improved antibody aggregate removal by hydroxyapatite chromatography in the presence of polyethylene glycolQ81503065
In vivo performance of two different hydroxyapatite coatings on titanium prepared by discharging in electrolytesQ81641368
Formation of cadmium sulfide nanoparticles in reverse micelles: extreme sensitivity to preparation procedureQ81905593
Development of gentamicin resistance after gentamicin-PMMA beads for treatment of foot osteomyelitis: report of two casesQ82158126
BMP-2/PLGA delayed-release microspheres composite graft, selection of bone particulate diameters, and prevention of aseptic inflammation for bone tissue engineeringQ82398514
Evaluation of in vitro serial antibiotic elution from meropenem-impregnated polymethylmethacrylate beads after ethylene oxide gas and autoclave sterilizationQ82584910
Biomimetic calcium phosphate coatings as bone morphogenetic protein delivery systems in spinal fusionQ82629527
Functionalized bridged silsesquioxane-based nanostructured microspheres: performance as novel drug-delivery devices in bone tissue-related applicationsQ82694721
Vancomycin-loaded nano-hydroxyapatite pellets to treat MRSA-induced chronic osteomyelitis with bone defect in rabbitsQ82902262
Calcium sulfates: what is the evidence?Q83024331
Management of osteoarticular infections caused by Staphylococcus aureus is similar to that of other etiologies: analysis of 199 staphylococcal bone and joint infectionsQ83095030
Macro-to-micro porous special bioactive glass and ceftriaxone-sulbactam composite drug delivery system for treatment of chronic osteomyelitis: an investigation through in vitro and in vivo animal trialQ83164051
Injectable and macroporous calcium phosphate cement scaffoldQ83227776
Gentamicin serum concentrations in patients with gentamicin-PMMA beads for infected hip joints: a prospective observational cohort studyQ83254428
Scavenging ROS: superoxide dismutase/catalase mimetics by the use of an oxidation-sensitive nanocarrier/enzyme conjugateQ83367321
Rapid resorption of calcium sulfate and hardware failure following corrective radius osteotomy: 2 case reportsQ83392452
Tunable metallicity of the La5/8Ca3/8MnO3(001) surface by an oxygen overlayerQ83419923
A chemical approach for cell-specific targeting of nanomaterials: small-molecule-initiated misfolding of nanoparticle corona proteinsQ83459464
Segmental bone regeneration using rhBMP-2-loaded collagen/chitosan microspheres composite scaffold in a rabbit modelQ83497500
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectosteomyelitisQ938983
P304page(s)1-59
P577publication date2015-01-01
P1433published inCritical Reviews in Therapeutic Drug Carrier SystemsQ15761680
P1476titleNanostructured platforms for the sustained and local delivery of antibiotics in the treatment of osteomyelitis
P478volume32

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