Substrate-Trapped Interactors of PHD3 and FIH Cluster in Distinct Signaling Pathways

scientific journal article

Substrate-Trapped Interactors of PHD3 and FIH Cluster in Distinct Signaling Pathways is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/J.CELREP.2016.02.043
P932PMC publication ID4805855
P698PubMed publication ID26972000
P5875ResearchGate publication ID297750324

P50authorAlex von KriegsheimQ41654542
Susan KennedyQ55979820
P2093author name stringAna Herrero
Javier Rodriguez
Amaya Garcia Munoz
Lan K. Nguyen
Naser Monsefi
Ruth Pilkington
Nora Rauch
Cormac T. Taylor
P2860cites workHIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensingQ24291102
OS-9 interacts with hypoxia-inducible factor 1alpha and prolyl hydroxylases to promote oxygen-dependent degradation of HIF-1alphaQ24295172
Intracellular localisation of human HIF-1 alpha hydroxylases: implications for oxygen sensingQ24296765
The LIMD1 protein bridges an association between the prolyl hydroxylases and VHL to repress HIF-1 activityQ24303868
Pyruvate kinase M2 is a PHD3-stimulated coactivator for hypoxia-inducible factor 1Q24304533
Posttranslational hydroxylation of ankyrin repeats in IkappaB proteins by the hypoxia-inducible factor (HIF) asparaginyl hydroxylase, factor inhibiting HIF (FIH)Q24304828
Interaction proteome of human Hippo signaling: modular control of the co-activator YAP1Q24316087
cIAP1/2 are direct E3 ligases conjugating diverse types of ubiquitin chains to receptor interacting proteins kinases 1 to 4 (RIP1-4)Q24338276
RIP4 (DIK/PKK), a novel member of the RIP kinase family, activates NF-kappa B and is processed during apoptosis.Q24538893
The SCFbeta-TRCP-ubiquitin ligase complex associates specifically with phosphorylated destruction motifs in IkappaBalpha and beta-catenin and stimulates IkappaBalpha ubiquitination in vitroQ24608829
Rapid turnover of extracellular signal-regulated kinase 3 by the ubiquitin-proteasome pathway defines a novel paradigm of mitogen-activated protein kinase regulation during cellular differentiationQ24683060
Status of large-scale analysis of post-translational modifications by mass spectrometryQ26829144
Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylationQ27860876
Hypoxia-inducible factor (HIF) asparagine hydroxylase is identical to factor inhibiting HIF (FIH) and is related to the cupin structural familyQ28119190
Expanding chemical biology of 2-oxoglutarate oxygenasesQ28268841
Differential function of the prolyl hydroxylases PHD1, PHD2, and PHD3 in the regulation of hypoxia-inducible factorQ28271379
PHD1 links cell-cycle progression to oxygen sensing through hydroxylation of the centrosomal protein Cep192Q28296254
Inhibition of 2-oxoglutarate dependent oxygenasesQ28306956
Ubiquitin signalling in the NF-kappaB pathwayQ29616322
On-beads digestion in conjunction with data-dependent mass spectrometry: a shortcut to quantitative and dynamic interaction proteomicsQ30821897
Evolutionary conserved regulation of HIF-1β by NF-κB.Q33813506
Prolyl hydroxylation by EglN2 destabilizes FOXO3a by blocking its interaction with the USP9x deubiquitinaseQ33850553
Phosphorylation of Dishevelled by protein kinase RIPK4 regulates Wnt signalingQ33889161
Accurate proteome-wide label-free quantification by delayed normalization and maximal peptide ratio extraction, termed MaxLFQ.Q34157715
Prolyl hydroxylase-1 negatively regulates IkappaB kinase-beta, giving insight into hypoxia-induced NFkappaB activityQ35141643
Cell-to-cell variability in PI3K protein level regulates PI3K-AKT pathway activity in cell populationsQ36088956
PHD3-dependent hydroxylation of HCLK2 promotes the DNA damage responseQ36129082
Proteomics-based identification of novel factor inhibiting hypoxia-inducible factor (FIH) substrates indicates widespread asparaginyl hydroxylation of ankyrin repeat domain-containing proteins.Q37113887
Regulation of IL-1β-induced NF-κB by hydroxylases links key hypoxic and inflammatory signaling pathways.Q37319845
An ID2-dependent mechanism for VHL inactivation in cancerQ37741948
Label-free quantitative proteomics trends for protein-protein interactionsQ38059973
The impact of hypoxia on cell death pathwaysQ38091503
Label-free quantitative proteomics reveals the dynamics of proteasome complexes composition and stoichiometry in a wide range of human cell lines.Q38997541
Factor inhibiting HIF-1 (FIH-1) modulates protein interactions of apoptosis-stimulating p53 binding protein 2 (ASPP2).Q39162547
Pharmacological characterization of 1-(5-chloro-6-(trifluoromethoxy)-1H-benzoimidazol-2-yl)-1H-pyrazole-4-carboxylic acid (JNJ-42041935), a potent and selective hypoxia-inducible factor prolyl hydroxylase inhibitorQ39582018
Inhibitor of nuclear factor-kappaB alpha derepresses hypoxia-inducible factor-1 during moderate hypoxia by sequestering factor inhibiting hypoxia-inducible factor from hypoxia-inducible factor 1alphaQ39849203
Chaperones as thermodynamic sensors of drug-target interactions reveal kinase inhibitor specificities in living cellsQ41813875
ERK3 promotes endothelial cell functions by upregulating SRC-3/SP1-mediated VEGFR2 expressionQ41865012
A dynamic model of the hypoxia-inducible factor 1α (HIF-1α) networkQ43585049
Hypoxia differentially regulates VEGFR1 and VEGFR2 levels and alters intracellular signaling and cell migration in endothelial cells.Q52846572
HGF induces epithelial-to-mesenchymal transition by modulating the mammalian hippo/MST2 and ISG15 pathways.Q54357218
Oxygen-dependent ATF-4 stability is mediated by the PHD3 oxygen sensorQ64005208
Mechanisms of endothelial response to oxidative aggression: protective role of autologous VEGF and induction of VEGFR2 by H2O2Q80088244
P433issue11
P304page(s)2745–2760
P577publication date2016-03-22
P1433published inCell ReportsQ5058165
P1476titleSubstrate-Trapped Interactors of PHD3 and FIH Cluster in Distinct Signaling Pathways
P478volume14