scholarly article | Q13442814 |
P50 | author | Alex von Kriegsheim | Q41654542 |
Susan Kennedy | Q55979820 | ||
P2093 | author name string | Ana Herrero | |
Javier Rodriguez | |||
Amaya Garcia Munoz | |||
Lan K. Nguyen | |||
Naser Monsefi | |||
Ruth Pilkington | |||
Nora Rauch | |||
Cormac T. Taylor | |||
P2860 | cites work | HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing | Q24291102 |
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Intracellular localisation of human HIF-1 alpha hydroxylases: implications for oxygen sensing | Q24296765 | ||
The LIMD1 protein bridges an association between the prolyl hydroxylases and VHL to repress HIF-1 activity | Q24303868 | ||
Pyruvate kinase M2 is a PHD3-stimulated coactivator for hypoxia-inducible factor 1 | Q24304533 | ||
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Interaction proteome of human Hippo signaling: modular control of the co-activator YAP1 | Q24316087 | ||
cIAP1/2 are direct E3 ligases conjugating diverse types of ubiquitin chains to receptor interacting proteins kinases 1 to 4 (RIP1-4) | Q24338276 | ||
RIP4 (DIK/PKK), a novel member of the RIP kinase family, activates NF-kappa B and is processed during apoptosis. | Q24538893 | ||
The SCFbeta-TRCP-ubiquitin ligase complex associates specifically with phosphorylated destruction motifs in IkappaBalpha and beta-catenin and stimulates IkappaBalpha ubiquitination in vitro | Q24608829 | ||
Rapid turnover of extracellular signal-regulated kinase 3 by the ubiquitin-proteasome pathway defines a novel paradigm of mitogen-activated protein kinase regulation during cellular differentiation | Q24683060 | ||
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Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation | Q27860876 | ||
Hypoxia-inducible factor (HIF) asparagine hydroxylase is identical to factor inhibiting HIF (FIH) and is related to the cupin structural family | Q28119190 | ||
Expanding chemical biology of 2-oxoglutarate oxygenases | Q28268841 | ||
Differential function of the prolyl hydroxylases PHD1, PHD2, and PHD3 in the regulation of hypoxia-inducible factor | Q28271379 | ||
PHD1 links cell-cycle progression to oxygen sensing through hydroxylation of the centrosomal protein Cep192 | Q28296254 | ||
Inhibition of 2-oxoglutarate dependent oxygenases | Q28306956 | ||
Ubiquitin signalling in the NF-kappaB pathway | Q29616322 | ||
On-beads digestion in conjunction with data-dependent mass spectrometry: a shortcut to quantitative and dynamic interaction proteomics | Q30821897 | ||
Evolutionary conserved regulation of HIF-1β by NF-κB. | Q33813506 | ||
Prolyl hydroxylation by EglN2 destabilizes FOXO3a by blocking its interaction with the USP9x deubiquitinase | Q33850553 | ||
Phosphorylation of Dishevelled by protein kinase RIPK4 regulates Wnt signaling | Q33889161 | ||
Accurate proteome-wide label-free quantification by delayed normalization and maximal peptide ratio extraction, termed MaxLFQ. | Q34157715 | ||
Prolyl hydroxylase-1 negatively regulates IkappaB kinase-beta, giving insight into hypoxia-induced NFkappaB activity | Q35141643 | ||
Cell-to-cell variability in PI3K protein level regulates PI3K-AKT pathway activity in cell populations | Q36088956 | ||
PHD3-dependent hydroxylation of HCLK2 promotes the DNA damage response | Q36129082 | ||
Proteomics-based identification of novel factor inhibiting hypoxia-inducible factor (FIH) substrates indicates widespread asparaginyl hydroxylation of ankyrin repeat domain-containing proteins. | Q37113887 | ||
Regulation of IL-1β-induced NF-κB by hydroxylases links key hypoxic and inflammatory signaling pathways. | Q37319845 | ||
An ID2-dependent mechanism for VHL inactivation in cancer | Q37741948 | ||
Label-free quantitative proteomics trends for protein-protein interactions | Q38059973 | ||
The impact of hypoxia on cell death pathways | Q38091503 | ||
Label-free quantitative proteomics reveals the dynamics of proteasome complexes composition and stoichiometry in a wide range of human cell lines. | Q38997541 | ||
Factor inhibiting HIF-1 (FIH-1) modulates protein interactions of apoptosis-stimulating p53 binding protein 2 (ASPP2). | Q39162547 | ||
Pharmacological characterization of 1-(5-chloro-6-(trifluoromethoxy)-1H-benzoimidazol-2-yl)-1H-pyrazole-4-carboxylic acid (JNJ-42041935), a potent and selective hypoxia-inducible factor prolyl hydroxylase inhibitor | Q39582018 | ||
Inhibitor of nuclear factor-kappaB alpha derepresses hypoxia-inducible factor-1 during moderate hypoxia by sequestering factor inhibiting hypoxia-inducible factor from hypoxia-inducible factor 1alpha | Q39849203 | ||
Chaperones as thermodynamic sensors of drug-target interactions reveal kinase inhibitor specificities in living cells | Q41813875 | ||
ERK3 promotes endothelial cell functions by upregulating SRC-3/SP1-mediated VEGFR2 expression | Q41865012 | ||
A dynamic model of the hypoxia-inducible factor 1α (HIF-1α) network | Q43585049 | ||
Hypoxia differentially regulates VEGFR1 and VEGFR2 levels and alters intracellular signaling and cell migration in endothelial cells. | Q52846572 | ||
HGF induces epithelial-to-mesenchymal transition by modulating the mammalian hippo/MST2 and ISG15 pathways. | Q54357218 | ||
Oxygen-dependent ATF-4 stability is mediated by the PHD3 oxygen sensor | Q64005208 | ||
Mechanisms of endothelial response to oxidative aggression: protective role of autologous VEGF and induction of VEGFR2 by H2O2 | Q80088244 | ||
P433 | issue | 11 | |
P304 | page(s) | 2745–2760 | |
P577 | publication date | 2016-03-22 | |
P1433 | published in | Cell Reports | Q5058165 |
P1476 | title | Substrate-Trapped Interactors of PHD3 and FIH Cluster in Distinct Signaling Pathways | |
P478 | volume | 14 |