Substantial increase in mutations in the genes pfdhfr and pfdhps puts sulphadoxine-pyrimethamine-based intermittent preventive treatment for malaria at risk in Burkina Faso

scientific article (publication date: June 2014)

Substantial increase in mutations in the genes pfdhfr and pfdhps puts sulphadoxine-pyrimethamine-based intermittent preventive treatment for malaria at risk in Burkina Faso is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1111/TMI.12305
P3181OpenCitations bibliographic resource ID2265461
P698PubMed publication ID24674355

P50authorAli SieQ56376466
Michael LanzerQ80359367
P2093author name stringBoubacar Coulibaly
Cecilia Sanchez
Thomas Jänisch
Carolin Geiger
Guillaume Compaore
Martin Dittmer
P2860cites workSafety and efficacy of co-trimoxazole for treatment and prevention of Plasmodium falciparum malaria: a systematic reviewQ21133667
Efficacy of pyrimethamine-sulfadoxine in young children with uncomplicated falciparum malaria in rural Burkina FasoQ24803565
Safety of the methylene blue plus chloroquine combination in the treatment of uncomplicated falciparum malaria in young children of Burkina Faso [ISRCTN27290841]Q24815501
Evidence that a point mutation in dihydrofolate reductase-thymidylate synthase confers resistance to pyrimethamine in falciparum malariaQ27861937
Five years of antimalarial resistance marker surveillance in Gaza Province, Mozambique, following artemisinin-based combination therapy roll outQ28477515
Epidemiology of drug-resistant malariaQ30830669
The great failure of malaria control in Africa: a district perspective from Burkina FasoQ33286751
Intermittent screening and treatment versus intermittent preventive treatment of malaria in pregnancy: a randomised controlled non-inferiority trialQ33784329
Coverage of malaria protection in pregnant women in sub-Saharan Africa: a synthesis and analysis of national survey dataQ33805770
Five years of large-scale dhfr and dhps mutation surveillance following the phased implementation of artesunate plus sulfadoxine-pyrimethamine in Maputo Province, Southern Mozambique.Q33817503
Anti-folate drug resistance in Africa: meta-analysis of reported dihydrofolate reductase (dhfr) and dihydropteroate synthase (dhps) mutant genotype frequencies in African Plasmodium falciparum parasite populationsQ34134036
Malaria in a holoendemic area of Burkina Faso: a cross-sectional studyQ34485136
Therapeutic efficacy of sulphadoxine-pyrimethamine and chloroquine for the treatment of uncomplicated malaria in pregnancy in Burkina Faso.Q34944810
Pyrosequencing, a high-throughput method for detecting single nucleotide polymorphisms in the dihydrofolate reductase and dihydropteroate synthetase genes of Plasmodium falciparumQ35220888
Molecular markers in plasmodium falciparum linked to resistance to anti-malarial drugs in samples imported from Africa over an eight-year period (2002-2010): impact of the introduction of artemisinin combination therapyQ36051104
Temporal trends of sulphadoxine-pyrimethamine (SP) drug-resistance molecular markers in Plasmodium falciparum parasites from pregnant women in western KenyaQ36077922
Drug resistant Plasmodium falciparum in an area of seasonal transmissionQ36109401
Intermittent preventive treatment for the prevention of malaria during pregnancy in high transmission areasQ36316144
Declining malaria parasite prevalence and trends of asymptomatic parasitaemia in a seasonal transmission setting in North-Western Burkina Faso between 2000 and 2009-2012Q36803604
Access to malaria treatment in young children of rural Burkina FasoQ37465763
Intermittent preventive treatment against malaria: an updateQ37747411
Evolution of drug-resistance genes in Plasmodium falciparum in an area of seasonal malaria transmission in Eastern SudanQ38855059
Substandard anti-malarial drugs in Burkina FasoQ39124758
Chloroquine and sulphadoxine-pyrimethamine efficacy for uncomplicated malaria treatment and haematological recovery in children in Bobo-Dioulasso, Burkina Faso during a 3-year period 1998-2000.Q41916761
Sulfadoxine resistance in the human malaria parasite Plasmodium falciparum is determined by mutations in dihydropteroate synthetase and an additional factor associated with folate utilizationQ41928982
Monitoring for multidrug-resistant Plasmodium falciparum isolates and analysis of pyrimethamine resistance evolution in Uige province, AngolaQ41937703
Field-based evidence for linkage of mutations associated with chloroquine (pfcrt/pfmdr1) and sulfadoxine-pyrimethamine (pfdhfr/pfdhps) resistance and for the fitness cost of multiple mutations in P. falciparumQ41945406
Can pretreatment screening for dhps and dhfr point mutations in Plasmodium falciparum infections be used to predict sulfadoxine-pyrimethamine treatment failure?Q43699456
Molecular markers for failure of sulfadoxine-pyrimethamine and chlorproguanil-dapsone treatment of Plasmodium falciparum malariaQ43864384
High sensitivity of detection of human malaria parasites by the use of nested polymerase chain reactionQ48018672
P433issue6
P407language of work or nameEnglishQ1860
P921main subjectBurkina FasoQ965
malariaQ12156
sulfadoxineQ411557
pyrimethamineQ421072
PPPK-DHPSQ18970312
P304page(s)690-697
P577publication date2014-06-01
P1433published inTropical Medicine and International HealthQ15765747
P1476titleSubstantial increase in mutations in the genes pfdhfr and pfdhps puts sulphadoxine-pyrimethamine-based intermittent preventive treatment for malaria at risk in Burkina Faso
P478volume19

Reverse relations

cites work (P2860)
Q39413965Evaluation of Malaria Screening during Pregnancy with Rapid Diagnostic Tests Performed by Community Health Workers in Burkina Faso.
Q33617916Increase in the prevalence of mutations associated with sulfadoxine-pyrimethamine resistance in Plasmodium falciparum isolates collected from early to late pregnancy in Nanoro, Burkina Faso
Q28125934Increased Prevalence of Mutant Allele Pfdhps 437G and Pfdhfr Triple Mutation in Plasmodium falciparum Isolates from a Rural Area of Gabon, Three Years after the Change of Malaria Treatment Policy
Q53701891Molecular markers of resistance to amodiaquine plus sulfadoxine-pyrimethamine in an area with seasonal malaria chemoprevention in south central Niger.
Q28553597Parasitological Clearance Rates and Drug Concentrations of a Fixed Dose Combination of Azithromycin-Chloroquine in Asymptomatic Pregnant Women with Plasmodium Falciparum Parasitemia: An Open-Label, Non-Comparative Study in Sub-Saharan Africa
Q28125923Prevalence of the dhfr and dhps Mutations among Pregnant Women in Rural Burkina Faso Five Years after the Introduction of Intermittent Preventive Treatment with Sulfadoxine-Pyrimethamine
Q37602300Recent uptake of intermittent preventive treatment during pregnancy with sulfadoxine-pyrimethamine is associated with increased prevalence of Pfdhfr mutations in Bobo-Dioulasso, Burkina Faso

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