Characterization of drug resistance associated genetic polymorphisms among Plasmodium falciparum field isolates in Ujjain, Madhya Pradesh, India

scientific article (publication date: 15 May 2014)

Characterization of drug resistance associated genetic polymorphisms among Plasmodium falciparum field isolates in Ujjain, Madhya Pradesh, India is …
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P6179Dimensions Publication ID1026748650
P356DOI10.1186/1475-2875-13-182
P3181OpenCitations bibliographic resource ID3419667
P932PMC publication ID4036110
P698PubMed publication ID24885535
P5875ResearchGate publication ID262789753

P50authorJohan UrsingQ42134597
Vishal DiwanQ43155832
Ashish PathakQ55873725
Andreas MårtenssonQ91539704
P2093author name stringAshish Sharma
Jagdish Mandliya
Sudhir Gawariker
P2860cites workArtemisinin Resistance in Plasmodium falciparum MalariaQ22061852
Emergence of artemisinin-resistant malaria on the western border of Thailand: a longitudinal studyQ24598695
Pgh1 modulates sensitivity and resistance to multiple antimalarials in Plasmodium falciparumQ27861931
Evidence that a point mutation in dihydrofolate reductase-thymidylate synthase confers resistance to pyrimethamine in falciparum malariaQ27861937
Population genetic analyses of Plasmodium falciparum chloroquine receptor transporter gene haplotypes reveal the evolutionary history of chloroquine-resistant malaria in IndiaQ41933174
Low efficacy of chloroquine: time to switchover to artemisinin-based combination therapy for falciparum malaria in IndiaQ41938534
Emergence of an unusual sulfadoxine-pyrimethamine resistance pattern and a novel K540N mutation in dihydropteroate synthetase in Plasmodium falciparum isolates obtained from Car Nicobar Island, India, after the 2004 TsunamiQ41939113
Plasmodium falciparum genotypes associated with chloroquine and amodiaquine resistance in Guinea-BissauQ41943046
Decreasing pfmdr1 copy number in plasmodium falciparum malaria heightens susceptibility to mefloquine, lumefantrine, halofantrine, quinine, and artemisininQ41944932
Quinoline resistance associated polymorphisms in the pfcrt, pfmdr1 and pfmrp genes of Plasmodium falciparum in IranQ41945860
Molecular markers for failure of sulfadoxine-pyrimethamine and chlorproguanil-dapsone treatment of Plasmodium falciparum malariaQ43864384
Selection of pfmdr1 mutations after amodiaquine monotherapy and amodiaquine plus artemisinin combination therapy in East AfricaQ43945880
Ordered accumulation of mutations conferring resistance to sulfadoxine-pyrimethamine in the Plasmodium falciparum parasiteQ44208973
A selective sweep driven by pyrimethamine treatment in southeast asian malaria parasitesQ44495547
In vivo selection of Plasmodium falciparum pfmdr1 86N coding alleles by artemether-lumefantrine (Coartem).Q45270651
Multiplex PCR-RFLP methods for pfcrt, pfmdr1 and pfdhfr mutations in Plasmodium falciparumQ46930127
Mutations in dihydropteroate synthase are responsible for sulfone and sulfonamide resistance in Plasmodium falciparumQ27861947
Origin and evolution of sulfadoxine resistant Plasmodium falciparumQ28473479
Novel polymorphisms in Plasmodium falciparum ABC transporter genes are associated with major ACT antimalarial drug resistanceQ28478286
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Mutations in the P. falciparum digestive vacuole transmembrane protein PfCRT and evidence for their role in chloroquine resistanceQ29615118
Mefloquine resistance in Plasmodium falciparum and increased pfmdr1 gene copy numberQ29615128
A molecular marker for chloroquine-resistant falciparum malariaQ31921233
Evidence of selective sweeps in genes conferring resistance to chloroquine and pyrimethamine in Plasmodium falciparum isolates in IndiaQ33676392
Amino acid changes linked to pyrimethamine resistance in the dihydrofolate reductase-thymidylate synthase gene of Plasmodium falciparumQ33680054
Five years of large-scale dhfr and dhps mutation surveillance following the phased implementation of artesunate plus sulfadoxine-pyrimethamine in Maputo Province, Southern Mozambique.Q33817503
Current scenario of malaria in India.Q33852240
In vitro sensitivity of Plasmodium falciparum clinical isolates from the China-Myanmar border area to quinine and association with polymorphism in the Na+/H+ exchangerQ34151002
Prevalence of resistance associated polymorphisms in Plasmodium falciparum field isolates from southern PakistanQ34569732
Antimalarial drug resistance of Plasmodium falciparum in India: changes over time and spaceQ34743254
Selective sweeps and genetic lineages of plasmodium falciparum drug -resistant alleles in GhanaQ34763548
Polymorphism of Plasmodium falciparum Na(+)/H(+) exchanger is indicative of a low in vitro quinine susceptibility in isolates from Viet Nam.Q35069374
Clinical trial of extended-dose chloroquine for treatment of resistant falciparum malaria among Afghan refugees in PakistanQ35093449
Prevalence of mutations associated with higher levels of sulfadoxine-pyrimethamine resistance in Plasmodium falciparum isolates from Car Nicobar Island and Assam, IndiaQ35127900
Polymorphisms of the pfmdr1 but not the pfnhe-1 gene is associated with in vitro quinine sensitivity in Thai isolates of Plasmodium falciparumQ35782169
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pfmdr1 amplification is related to increased Plasmodium falciparum in vitro sensitivity to the bisquinoline piperaquineQ36086426
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Quinine treatment selects the pfnhe-1 ms4760-1 polymorphism in Malian patients with Falciparum malariaQ36509807
Plasmodium falciparum drug resistance phenotype as assessed by patient antimalarial drug levels and its association with pfmdr1 polymorphismsQ36584636
P. falciparum dihydrofolate reductase and dihydropteroate synthase mutations: epidemiology and role in clinical resistance to antifolatesQ36648400
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In vivo selection of Plasmodium falciparum parasites carrying the chloroquine-susceptible pfcrt K76 allele after treatment with artemether-lumefantrine in AfricaQ37283105
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Spread and evolution of Plasmodium falciparum drug resistanceQ37459709
Amino acids in the dihydrofolate reductase-thymidylate synthase gene of Plasmodium falciparum involved in cycloguanil resistance differ from those involved in pyrimethamine resistanceQ37739332
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The pfmdr1 gene is associated with a multidrug-resistant phenotype in Plasmodium falciparum from the western border of Thailand.Q39472395
Plasmodium falciparum isolates in India exhibit a progressive increase in mutations associated with sulfadoxine-pyrimethamine resistanceQ40622316
Dissecting the loci of low-level quinine resistance in malaria parasitesQ41914069
Multiple transporters associated with malaria parasite responses to chloroquine and quinineQ41915501
Prevalence of the K76T mutation in the pfcrt gene of Plasmodium falciparum among chloroquine responders in IndiaQ41915658
Analyses of genetic variations at microsatellite loci present in-and-around the Pfcrt gene in Indian Plasmodium falciparumQ41923716
Molecular monitoring of antimalarial drug resistance among Plasmodium falciparum field isolates from Odisha, IndiaQ41926973
A randomized, controlled, open-label trial evaluating the efficacy and safety of chloroquine in the treatment of giardiasis in children.Q41932433
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectIndiaQ668
Plasmodium falciparumQ311383
infectious diseaseQ18123741
P304page(s)182
P577publication date2014-05-15
P1433published inMalaria JournalQ15749954
P1476titleCharacterization of drug resistance associated genetic polymorphisms among Plasmodium falciparum field isolates in Ujjain, Madhya Pradesh, India
P478volume13