scholarly article | Q13442814 |
P356 | DOI | 10.1016/0092-8674(81)90015-5 |
P953 | full work available at URL | https://api.elsevier.com/content/article/PII:0092867481900155?httpAccept=text/plain |
https://api.elsevier.com/content/article/PII:0092867481900155?httpAccept=text/xml | ||
P3181 | OpenCitations bibliographic resource ID | 3186163 |
P698 | PubMed publication ID | 1651172 |
P5875 | ResearchGate publication ID | 21504908 |
P2093 | author name string | R. Li | |
A. W. Murray | |||
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Growth and the cell cycle of the yeast Saccharomyces cerevisiae. I. Slowing S phase or nuclear division decreases the G1 cell cycle period | Q70300672 | ||
P433 | issue | 3 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | transport protein | Q2111029 |
P304 | page(s) | 519-31 | |
P577 | publication date | 1991-08-09 | |
P1433 | published in | Cell | Q655814 |
P1476 | title | Feedback control of mitosis in budding yeast | |
P478 | volume | 66 |
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Q36892253 | 2-Aminopurine overrides multiple cell cycle checkpoints in BHK cells |
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Q38932588 | A chromosome separation checkpoint: A midzone Aurora B gradient mediates a chromosome separation checkpoint that regulates the anaphase-telophase transition. |
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Q40763320 | A critical role for Pin2/TRF1 in ATM-dependent regulation. Inhibition of Pin2/TRF1 function complements telomere shortening, radiosensitivity, and the G(2)/M checkpoint defect of ataxia-telangiectasia cells |
Q24601605 | A delay in the Saccharomyces cerevisiae cell cycle that is induced by a dicentric chromosome and dependent upon mitotic checkpoints |
Q24657816 | A direct link between sister chromatid cohesion and chromosome condensation revealed through the analysis of MCD1 in S. cerevisiae |
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Q39318959 | A global genetic interaction network maps a wiring diagram of cellular function |
Q28144150 | A human REV7 homolog that interacts with the polymerase zeta catalytic subunit hREV3 and the spindle assembly checkpoint protein hMAD2 |
Q33824711 | A long twentieth century of the cell cycle and beyond |
Q46882061 | A microbial avenue to cell cycle control in the plant superkingdom. |
Q28488783 | A minimal anaphase promoting complex/cyclosome (APC/C) in Trypanosoma brucei |
Q27338852 | A model for cell wall dissolution in mating yeast cells: polarized secretion and restricted diffusion of cell wall remodeling enzymes induces local dissolution |
Q36691222 | A mutation in PLC1, a candidate phosphoinositide-specific phospholipase C gene from Saccharomyces cerevisiae, causes aberrant mitotic chromosome segregation |
Q73747726 | A mutation in the spindle checkpoint arresting meiosis II in Brachiaria ruziziensis |
Q36948900 | A mutational analysis identifies three functional regions of the spindle pole component Spc110p in Saccharomyces cerevisiae |
Q27940112 | A novel protein complex promoting formation of functional alpha- and gamma-tubulin |
Q30635394 | A novel role of farnesylation in targeting a mitotic checkpoint protein, human Spindly, to kinetochores |
Q27933463 | A novel yeast screen for mitotic arrest mutants identifies DOC1, a new gene involved in cyclin proteolysis |
Q48365555 | A prize for proliferation |
Q26829071 | A quantitative model for cyclin-dependent kinase control of the cell cycle: revisited |
Q37293039 | A quantitative systems view of the spindle assembly checkpoint |
Q36254503 | A role for the actin cytoskeleton of Saccharomyces cerevisiae in bipolar bud-site selection |
Q37694823 | A role of Sep1 (= Kem1, Xrn1) as a microtubule-associated protein in Saccharomyces cerevisiae. |
Q34604392 | A screen for dynein synthetic lethals in Aspergillus nidulans identifies spindle assembly checkpoint genes and other genes involved in mitosis |
Q52546192 | A spindle checkpoint arrest and a cytokinesis failure by the dominant-negative polo-box domain of Plk1 in U-2 OS cells. |
Q30856481 | A spindle checkpoint functions during mitosis in the early Caenorhabditis elegans embryo |
Q35841722 | A stochastic model of kinetochore-microtubule attachment accurately describes fission yeast chromosome segregation. |
Q33969110 | A transgene-induced mitotic arrest mutation in the mouse allelic with Oligosyndactylism. |
Q33889060 | Abce1 orchestrates M-phase entry and cytoskeleton architecture in mouse oocyte |
Q24672009 | Aberrantly segregating centromeres activate the spindle assembly checkpoint in budding yeast |
Q37381888 | Abnormal kinetochore structure activates the spindle assembly checkpoint in budding yeast |
Q34605642 | Accumulation of mRNA coding for the ctf13p kinetochore subunit of Saccharomyces cerevisiae depends on the same factors that promote rapid decay of nonsense mRNAs |
Q52188536 | Activation of the metaphase checkpoint and an apoptosis programme in the early zebrafish embryo, by treatment with the spindle-destabilising agent nocodazole. |
Q41892358 | Active transport can greatly enhance Cdc20:Mad2 formation |
Q34042403 | Adaptive evolution of genes duplicated from the Drosophila pseudoobscura neo-X chromosome |
Q48060294 | An actin point-mutation neighboring the 'hydrophobic plug' causes defects in the maintenance of cell polarity and septum organization in the fission yeast Schizosaccharomyces pombe |
Q34615442 | An alpha-tubulin mutant demonstrates distinguishable functions among the spindle assembly checkpoint genes in Saccharomyces cerevisiae. |
Q37621424 | An essential single domain response regulator required for normal cell division and differentiation in Caulobacter crescentus. |
Q43181718 | An inhibitor of yeast cyclin-dependent protein kinase plays an important role in ensuring the genomic integrity of daughter cells |
Q36065506 | An oncogenic form of p53 confers a dominant, gain-of-function phenotype that disrupts spindle checkpoint control |
Q37454676 | Analysis of Ipl1-mediated phosphorylation of the Ndc80 kinetochore protein in Saccharomyces cerevisiae |
Q36117257 | Analysis of kinesin motor function at budding yeast kinetochores. |
Q33959832 | Analysis of mitotic and meiotic defects in Saccharomyces cerevisiae SRS2 DNA helicase mutants |
Q24303505 | Anaphase initiation is regulated by antagonistic ubiquitination and deubiquitination activities |
Q36234928 | Anaphase onset in vertebrate somatic cells is controlled by a checkpoint that monitors sister kinetochore attachment to the spindle |
Q74140502 | Anaphase spindle position is monitored by the BUB2 checkpoint |
Q36837323 | Aneuploidy and tumorigenesis |
Q33361288 | Arabidopsis COPPER MODIFIED RESISTANCE1/PATRONUS1 is essential for growth adaptation to stress and required for mitotic onset control |
Q36532043 | Astral microtubules are not required for anaphase B in Saccharomyces cerevisiae |
Q48042125 | BRK1, a Bub1-related kinase, is essential for generating proper tension between homologous kinetochores at metaphase I of rice meiosis |
Q39144762 | BUB1 and BUBR1 inhibition decreases proliferation and colony formation, and enhances radiation sensitivity in pediatric glioblastoma cells |
Q36118820 | BUB1 mediation of caspase-independent mitotic death determines cell fate |
Q33838181 | BUB3 that dissociates from BUB1 activates caspase-independent mitotic death (CIMD). |
Q36129382 | Basic mechanism of eukaryotic chromosome segregation |
Q27936221 | Bet2p and Mad2p are components of a prenyltransferase that adds geranylgeranyl onto Ypt1p and Sec4p |
Q34688467 | Bi-orienting chromosomes on the mitotic spindle. |
Q27934394 | Bifurcation of the mitotic checkpoint pathway in budding yeast |
Q35610652 | Biophysics of mitosis |
Q36986542 | Bipolar orientation of chromosomes in Saccharomyces cerevisiae is monitored by Mad1 and Mad2, but not by Mad3. |
Q28586838 | Bora regulates meiotic spindle assembly and cell cycle during mouse oocyte meiosis |
Q37527786 | Boveri revisited: chromosomal instability, aneuploidy and tumorigenesis |
Q37882877 | Bub1 and BubR1: at the interface between chromosome attachment and the spindle checkpoint |
Q32080019 | Bub1 is activated by the protein kinase p90(Rsk) during Xenopus oocyte maturation |
Q27932473 | Bub1 kinase targets Sgo1 to ensure efficient chromosome biorientation in budding yeast mitosis |
Q41969716 | Bub1 positions Mad1 close to KNL1 MELT repeats to promote checkpoint signalling |
Q27343104 | Bub1-mediated adaptation of the spindle checkpoint |
Q33786507 | Bub1p kinase activates the Saccharomyces cerevisiae spindle assembly checkpoint |
Q24600680 | Bub3 gene disruption in mice reveals essential mitotic spindle checkpoint function during early embryogenesis |
Q21142712 | Bub3 is a spindle assembly checkpoint protein regulating chromosome segregation during mouse oocyte meiosis |
Q27310404 | Bub3 promotes Cdc20-dependent activation of the APC/C in S. cerevisiae |
Q27680055 | Bub3 reads phosphorylated MELT repeats to promote spindle assembly checkpoint signaling |
Q27933303 | Budding yeast Bub2 is localized at spindle pole bodies and activates the mitotic checkpoint via a different pathway from Mad2 |
Q27931347 | Budding yeast SKP1 encodes an evolutionarily conserved kinetochore protein required for cell cycle progression |
Q55202939 | Budding-like division of all-aqueous emulsion droplets modulated by networks of protein nanofibrils. |
Q41764313 | Bypassing anaphase by fission yeast cut9 mutation: requirement of cut9+ to initiate anaphase |
Q38744041 | C-terminal region of Mad2 plays an important role during mitotic spindle checkpoint in fission yeast Schizosaccharomyces pombe. |
Q36643228 | CDC44: a putative nucleotide-binding protein required for cell cycle progression that has homology to subunits of replication factor C |
Q36233891 | CENP-C is required for maintaining proper kinetochore size and for a timely transition to anaphase. |
Q46518322 | CENP-E as an essential component of the mitotic checkpoint in vitro. |
Q38309596 | CENP-E forms a link between attachment of spindle microtubules to kinetochores and the mitotic checkpoint |
Q30409397 | CENP-I and Aurora B act as a molecular switch that ties RZZ/Mad1 recruitment to kinetochore attachment status. |
Q27932199 | CHL1 is a nuclear protein with an essential ATP binding site that exhibits a size-dependent effect on chromosome segregation. |
Q27933949 | CIK1: a developmentally regulated spindle pole body-associated protein important for microtubule functions in Saccharomyces cerevisiae |
Q35558747 | Ca2+ triggers premature inactivation of the cdc2 protein kinase in permeabilized sea urchin embryos |
Q91812482 | CaMad2 Promotes Multiple Aspects of Genome Stability Beyond Its Direct Function in Chromosome Segregation |
Q47158462 | Caenorhabditis elegans BUB-3 and SAN-1/MAD3 Spindle Assembly Checkpoint Components Are Required for Genome Stability in Response to Treatment with Ionizing Radiation |
Q30871076 | Cancer risk and the ATM gene: a continuing debate |
Q24598333 | Carboxyl methylation of the phosphoprotein phosphatase 2A catalytic subunit promotes its functional association with regulatory subunits in vivo |
Q43089427 | Catalytic assembly of the mitotic checkpoint inhibitor BubR1-Cdc20 by a Mad2-induced functional switch in Cdc20. |
Q36328318 | Cdc28 activates exit from mitosis in budding yeast. |
Q27931065 | Cdc55p, the B-type regulatory subunit of protein phosphatase 2A, has multiple functions in mitosis and is required for the kinetochore/spindle checkpoint in Saccharomyces cerevisiae |
Q51811223 | Cell Cycle Synchronization of HeLa Cells to Assay EGFR Pathway Activation. |
Q33960935 | Cell cycle arrest of cdc mutants and specificity of the RAD9 checkpoint. |
Q37187614 | Cell cycle regulation by checkpoints |
Q40781233 | Cell cycle-dependent interaction of Mad2 with conserved Box1/2 region of human granulocyte-macrophage colony-stimulating factor receptor common betac |
Q41642289 | Cell cycle: checkpoint proteins and kinetochores |
Q52855268 | Cell division: Mitotic regulation comes into focus. |
Q39963723 | Cell-cycle dependent phosphorylation of yeast pericentrin regulates γ-TuSC-mediated microtubule nucleation. |
Q35196610 | Cellular transformation by the HTLV-I Tax protein, a jack-of-all-trades |
Q24563870 | Centromere DNA mutations induce a mitotic delay in Saccharomyces cerevisiae |
Q33632358 | Centromere proteins and chromosome inheritance: a complex affair. |
Q24316292 | Centromere-associated protein-E is essential for the mammalian mitotic checkpoint to prevent aneuploidy due to single chromosome loss |
Q35657719 | Centromere-tethered Mps1 pombe homolog (Mph1) kinase is a sufficient marker for recruitment of the spindle checkpoint protein Bub1, but not Mad1. |
Q38209751 | Centromeres and kinetochores of Brassicaceae. |
Q29547850 | Centromeres and kinetochores: from epigenetics to mitotic checkpoint signaling |
Q41441718 | Centromeres, checkpoints and chromatid cohesion. |
Q38481725 | Centromeric chromatin and its dynamics in plants |
Q34818183 | Centrosomes and checkpoints: the MPS1 family of kinases |
Q27305285 | Cep55 regulates spindle organization and cell cycle progression in meiotic oocyte. |
Q40443451 | Chapter 5 Cell Cycle Analysis of Apoptosis Using Flow Cytometry |
Q22009979 | Characterization of MAD2B and other mitotic spindle checkpoint genes |
Q28540742 | Characterization of a putative spindle assembly checkpoint kinase Mps1, suggests its involvement in cell division, morphogenesis and oxidative stress tolerance in Candida albicans |
Q34846703 | Characterization of chromosome stability in diploid, polyploid and hybrid yeast cells |
Q44013190 | Characterization of regions in hsMAD1 needed for binding hsMAD2. A polymorphic change in an hsMAD1 leucine zipper affects MAD1-MAD2 interaction and spindle checkpoint function |
Q46711511 | Characterization of spindle assembly checkpoint in Xenopus egg extracts |
Q24515331 | Characterization of the enzymatic activity of hChlR1, a novel human DNA helicase |
Q42638933 | Characterization of the genes encoding for MAD2 homologues in wheat |
Q22003896 | Characterization of the kinetochore binding domain of CENP-E reveals interactions with the kinetochore proteins CENP-F and hBUBR1 |
Q39574377 | Characterization of the p53-dependent postmitotic checkpoint following spindle disruption |
Q90407108 | Characterization of unconventional kinetochore kinases KKT10/19 in Trypanosoma brucei |
Q64062627 | Checkpoint Proteins Bub1 and Bub3 Delay Anaphase Onset in Response to Low Tension Independent of Microtubule-Kinetochore Detachment |
Q24651015 | Checkpoint genes required to delay cell division in response to nocodazole respond to impaired kinetochore function in the yeast Saccharomyces cerevisiae |
Q24670095 | Checkpoint inhibition of the APC/C in HeLa cells is mediated by a complex of BUBR1, BUB3, CDC20, and MAD2 |
Q24548359 | Checkpoint protein BubR1 acts synergistically with Mad2 to inhibit anaphase-promoting complex |
Q59023692 | Checkpoints and spindles |
Q34271224 | Checkpoints couple transcription network oscillator dynamics to cell-cycle progression |
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Q40976743 | Chk1 complements the G2/M checkpoint defect and radiosensitivity of ataxia-telangiectasia cells |
Q27932943 | Chl1p, a DNA helicase-like protein in budding yeast, functions in sister-chromatid cohesion |
Q27932579 | Chromatin assembly factor I and Hir proteins contribute to building functional kinetochores in S. cerevisiae. |
Q35148531 | Chromatin remodeling in mammalian zygotes |
Q39787703 | Chromosomal instability syndrome of total premature chromatid separation with mosaic variegated aneuploidy is defective in mitotic-spindle checkpoint. |
Q43938500 | Chromosome V loss due to centromere knockout or MAD2-deletion is immediately followed by restitution of homozygous diploidy in Saccharomyces cerevisiae |
Q28588417 | Chromosome missegregation and apoptosis in mice lacking the mitotic checkpoint protein Mad2 |
Q33952942 | Chromosome rearrangements and aneuploidy in yeast strains lacking both Tel1p and Mec1p reflect deficiencies in two different mechanisms |
Q34119639 | Chromosome segregation and cancer: cutting through the mystery |
Q38176326 | Chromosome segregation in budding yeast: sister chromatid cohesion and related mechanisms. |
Q42944697 | Co-activator independent differences in how the metaphase and anaphase APC/C recognise the same substrate. |
Q46056223 | Combination analysis of Bub1 and Mad2 expression in endometrial cancer: act as a prognostic factor in endometrial cancer |
Q33959237 | Commitment to meiosis in Saccharomyces cerevisiae: involvement of the SPO14 gene |
Q38406718 | Comparative analysis of chromosome segregation in human, yeasts and trypanosome |
Q38463989 | Comparative analysis of chrysanthemum transcriptome in response to three RNA viruses: Cucumber mosaic virus, Tomato spotted wilt virus and Potato virus X. |
Q33952888 | Comparative genetic analysis of PP2A-Cdc55 regulators in budding yeast |
Q37357807 | Complete loss of the tumor suppressor MAD2 causes premature cyclin B degradation and mitotic failure in human somatic cells. |
Q27938873 | Complex formation between Mad1p, Bub1p and Bub3p is crucial for spindle checkpoint function |
Q35598449 | Components of the spindle assembly checkpoint regulate the anaphase-promoting complex during meiosis in Caenorhabditis elegans |
Q33882831 | Components of the spindle-assembly checkpoint are essential in Caenorhabditis elegans |
Q41841209 | Condensin function at centromere chromatin facilitates proper kinetochore tension and ensures correct mitotic segregation of sister chromatids. |
Q33944098 | Conditional mutations in gamma-tubulin reveal its involvement in chromosome segregation and cytokinesis |
Q89565601 | Connecting GCN5's centromeric SAGA to the mitotic tension-sensing checkpoint |
Q30300041 | Connecting the microtubule attachment status of each kinetochore to cell cycle arrest through the spindle assembly checkpoint |
Q38025305 | Connecting up and clearing out: how kinetochore attachment silences the spindle assembly checkpoint. |
Q27936969 | Control of mitotic events by Nap1 and the Gin4 kinase |
Q33785051 | Control of mitotic transitions by the anaphase-promoting complex |
Q30657692 | Control of the spindle checkpoint by lateral kinetochore attachment and limited Mad1 recruitment |
Q47149511 | Coordination of Cell Cycle Progression and Mitotic Spindle Assembly Involves Histone H3 Lysine 4 Methylation by Set1/COMPASS. |
Q41678512 | Coupling cell division and cell death to microtubule dynamics |
Q35405693 | Creative blocks: cell-cycle checkpoints and feedback controls |
Q27936904 | Ctf19p: A novel kinetochore protein in Saccharomyces cerevisiae and a potential link between the kinetochore and mitotic spindle |
Q27939220 | Ctf7p is essential for sister chromatid cohesion and links mitotic chromosome structure to the DNA replication machinery |
Q38336330 | Cut1 is loaded onto the spindle by binding to Cut2 and promotes anaphase spindle movement upon Cut2 proteolysis. |
Q34645625 | Cyclin B-cdk activity stimulates meiotic rereplication in budding yeast |
Q53500608 | Cyclin B1: conductor of mitotic symphony orchestra. |
Q41515285 | Death and dying in the immune system |
Q27933329 | Defects in Saccharomyces cerevisiae protein phosphatase type I activate the spindle/kinetochore checkpoint |
Q35130588 | Defining genome maintenance pathways using functional genomic approaches |
Q52727074 | Degradation of cyclin B is critical for nuclear division in Trypanosoma brucei. |
Q37375667 | Delays in anaphase initiation occur in individual nuclei of the syncytial Drosophila embryo |
Q28478069 | Deletion of Cryptococcus neoformans AIF ortholog promotes chromosome aneuploidy and fluconazole-resistance in a metacaspase-independent manner |
Q53599454 | Deletion of RNQ1 gene reveals novel functional relationship between divergently transcribed Bik1p/CLIP-170 and Sfi1p in spindle pole body separation. |
Q34618102 | Depletion of H2A-H2B dimers in Saccharomyces cerevisiae triggers meiotic arrest by reducing IME1 expression and activating the BUB2-dependent branch of the spindle checkpoint |
Q24307413 | Determinants of conformational dimerization of Mad2 and its inhibition by p31comet |
Q40568327 | Different spindle checkpoint proteins monitor microtubule attachment and tension at kinetochores in Drosophila cells |
Q30464717 | Differential expression of a phosphoepitope at the kinetochores of moving chromosomes |
Q30452670 | Differential requirements for DNA replication in the activation of mitotic checkpoints in Saccharomyces cerevisiae |
Q30660029 | Disruption of astral microtubule contact with the cell cortex activates a Bub1, Bub3, and Mad3-dependent checkpoint in fission yeast |
Q30437632 | Dissection of CENP-C-directed centromere and kinetochore assembly |
Q27932972 | Distinct chromosome segregation roles for spindle checkpoint proteins |
Q37380779 | Distinct roles of yeast MEC and RAD checkpoint genes in transcriptional induction after DNA damage and implications for function. |
Q30438021 | Diverse functions of spindle assembly checkpoint genes in Saccharomyces cerevisiae |
Q38357646 | Dominant mutant alleles of yeast protein kinase gene CDC15 suppress the lte1 defect in termination of M phase and genetically interact with CDC14. |
Q36964541 | Drugs affecting microtubule dynamics increase alpha-tubulin mRNA accumulation via transcription in Tetrahymena thermophila |
Q50462324 | Dynamic location changes of Bub1-phosphorylated-H2AThr133 with CENH3 nucleosome in maize centromeric regions. |
Q34706505 | EMB-30: an APC4 homologue required for metaphase-to-anaphase transitions during meiosis and mitosis in Caenorhabditis elegans |
Q42375488 | Effective killing of the human pathogen Candida albicans by a specific inhibitor of non-essential mitotic kinesin Kip1p |
Q24300354 | Emi1 stably binds and inhibits the anaphase-promoting complex/cyclosome as a pseudosubstrate inhibitor |
Q34042513 | Endopolyploidization and flowering time are antagonistically regulated by checkpoint component MAD1 and immunity modulator MOS1. |
Q37329182 | Enhanced genomic instabilities caused by deregulated microtubule dynamics and chromosome segregation: a perspective from genetic studies in mice |
Q32030852 | Entry into mitosis in vertebrate somatic cells is guarded by a chromosome damage checkpoint that reverses the cell cycle when triggered during early but not late prophase |
Q27934638 | Esa1p is an essential histone acetyltransferase required for cell cycle progression |
Q35936918 | Essential tension and constructive destruction: the spindle checkpoint and its regulatory links with mitotic exit |
Q33772035 | Evaluating putative mechanisms of the mitotic spindle checkpoint |
Q22010696 | Evidence for an interaction of the metalloprotease-disintegrin tumour necrosis factor alpha convertase (TACE) with mitotic arrest deficient 2 (MAD2), and of the metalloprotease-disintegrin MDC9 with a novel MAD2-related protein, MAD2beta |
Q30454198 | Evidence that replication fork components catalyze establishment of cohesion between sister chromatids |
Q29619579 | Evidence that the Ipl1-Sli15 (Aurora kinase-INCENP) complex promotes chromosome bi-orientation by altering kinetochore-spindle pole connections |
Q27934598 | Evidence that the pre-mRNA splicing factor Clf1p plays a role in DNA replication in Saccharomyces cerevisiae. |
Q38103341 | Evolutionary cell biology of chromosome segregation: insights from trypanosomes |
Q34354345 | Evolutionary conservation between budding yeast and human kinetochores |
Q90186568 | Evolutionary repair: Changes in multiple functional modules allow meiotic cohesin to support mitosis |
Q54968396 | Exit from Exit |
Q42252113 | Explaining the oligomerization properties of the spindle assembly checkpoint protein Mad2. |
Q41834181 | Expression of mitotic-arrest deficiency 2 predicts the efficacy of neoadjuvant chemotherapy for locally advanced uterine cervical cancer |
Q30450260 | Expression of p60v-src in Saccharomyces cerevisiae results in elevation of p34CDC28 kinase activity and release of the dependence of DNA replication on mitosis |
Q35866745 | Expression profiles of cohesins, shugoshins and spindle assembly checkpoint genes in rhesus macaque oocytes predict their susceptibility for aneuploidy during embryonic development |
Q37341109 | Family cancer syndromes: inherited deficiencies in systems for the maintenance of genomic integrity |
Q92002816 | Fanconi Anemia Pathway: Mechanisms of Breast Cancer Predisposition Development and Potential Therapeutic Targets |
Q36234389 | Feedback control of the metaphase-anaphase transition in sea urchin zygotes: role of maloriented chromosomes |
Q35916072 | Fission yeast Cut1 and Cut2 are essential for sister chromatid separation, concentrate along the metaphase spindle and form large complexes. |
Q39674358 | Fission yeast Mad3p is required for Mad2p to inhibit the anaphase-promoting complex and localizes to kinetochores in a Bub1p-, Bub3p-, and Mph1p-dependent manner |
Q36328520 | Fission yeast bub1 is a mitotic centromere protein essential for the spindle checkpoint and the preservation of correct ploidy through mitosis |
Q27323083 | Fission yeast cells undergo nuclear division in the absence of spindle microtubules |
Q39645373 | Fission yeast ch-TOG/XMAP215 homologue Alp14 connects mitotic spindles with the kinetochore and is a component of the Mad2-dependent spindle checkpoint |
Q36563505 | Fission yeast mal2+ is required for chromosome segregation |
Q70874881 | Fission yeast sta mutations that stabilize an unstable minichromosome are novel cdc2-interacting suppressors and are involved in regulation of spindle dynamics |
Q52545781 | Frequent impairment of the spindle assembly checkpoint in hepatocellular carcinoma. |
Q39735633 | Function of Cdc2p-dependent Bub1p phosphorylation and Bub1p kinase activity in the mitotic and meiotic spindle checkpoint |
Q58269502 | Functional analysis of the putativeBUB2homologues ofc. elegansin the spindle position checkpoint |
Q26998944 | Functional characterization of Anaphase Promoting Complex/Cyclosome (APC/C) E3 ubiquitin ligases in tumorigenesis |
Q35613800 | Functions and mechanisms of action of the adenovirus E3 proteins |
Q91603671 | G2/M inhibitors as pharmacotherapeutic opportunities for glioblastoma: the old, the new, and the future |
Q27930056 | GDI1 encodes a GDP dissociation inhibitor that plays an essential role in the yeast secretory pathway |
Q46864873 | GFP tagging of budding yeast chromosomes reveals that protein-protein interactions can mediate sister chromatid cohesion |
Q34070007 | Gamma-tubulin regulates the anaphase-promoting complex/cyclosome during interphase. |
Q34174719 | Gene disruption of a G4-DNA-dependent nuclease in yeast leads to cellular senescence and telomere shortening |
Q60046564 | Gene expression profiling of spontaneously occurring canine mammary tumours: Insight into gene networks and pathways linked to cancer pathogenesis |
Q33910498 | Generating chromosome instability through the simultaneous deletion of Mad2 and p53. |
Q36566041 | Genes encoding farnesyl cysteine carboxyl methyltransferase in Schizosaccharomyces pombe and Xenopus laevis |
Q33695832 | Genetic analysis of the kinetochore DASH complex reveals an antagonistic relationship with the ras/protein kinase A pathway and a novel subunit required for Ask1 association |
Q33804007 | Genetic instability and darwinian selection in tumours |
Q56687584 | Genetic instability and darwinian selection in tumours |
Q28264035 | Genetic instability in budding and fission yeast-sources and mechanisms |
Q94592117 | Genetic interactions derived from high-throughput phenotyping of 6589 yeast cell cycle mutants |
Q55214782 | Genomic Instability and Cancer. |
Q33965829 | Global analysis of core histones reveals nucleosomal surfaces required for chromosome bi-orientation. |
Q24338299 | Hec1 sequentially recruits Zwint-1 and ZW10 to kinetochores for faithful chromosome segregation and spindle checkpoint control |
Q36955942 | Histone H3K4 methylation regulates deactivation of the spindle assembly checkpoint through direct binding of Mad2 |
Q34481942 | Histone methyltransferases MES-4 and MET-1 promote meiotic checkpoint activation in Caenorhabditis elegans |
Q30305835 | Histone-histone interactions and centromere function |
Q21203559 | How eggs arrest at metaphase II: MPF stabilisation plus APC/C inhibition equals Cytostatic Factor |
Q22010522 | Human BUBR1 is a mitotic checkpoint kinase that monitors CENP-E functions at kinetochores and binds the cyclosome/APC |
Q24299555 | Human Blinkin/AF15q14 is required for chromosome alignment and the mitotic checkpoint through direct interaction with Bub1 and BubR1 |
Q24682987 | Human MPS1 kinase is required for mitotic arrest induced by the loss of CENP-E from kinetochores |
Q24536263 | Human Mps1 kinase is required for the spindle assembly checkpoint but not for centrosome duplication |
Q24569635 | Human Mps1 protein kinase is required for centrosome duplication and normal mitotic progression |
Q24336250 | Human T cell leukemia virus type 1 oncoprotein Tax targets the human mitotic checkpoint protein MAD1 |
Q24290711 | Human Zw10 and ROD are mitotic checkpoint proteins that bind to kinetochores |
Q39322531 | Human papillomavirus type 16 E7 oncoprotein engages but does not abrogate the mitotic spindle assembly checkpoint |
Q39869741 | Hybrids of aneuploid human cancer cells permit complementation of simple and complex cancer defects |
Q27939815 | IBD2 encodes a novel component of the Bub2p-dependent spindle checkpoint in the budding yeast Saccharomyces cerevisiae |
Q77343497 | Ibd1p, a possible spindle pole body associated protein, regulates nuclear division and bud separation in Saccharomyces cerevisiae |
Q27935756 | Identification and cloning of the CHL4 gene controlling chromosome segregation in yeast. |
Q27938555 | Identification of RFC(Ctf18p, Ctf8p, Dcc1p): an alternative RFC complex required for sister chromatid cohesion in S. cerevisiae |
Q24321983 | Identification of a MAD2-binding protein, CMT2, and its role in mitosis |
Q36259420 | Identification of a mid-anaphase checkpoint in budding yeast |
Q27935018 | Identification of a mutation causing a defective spindle assembly checkpoint in high ethyl caproate-producing sake yeast strain K1801. |
Q24550894 | Identification of an overlapping binding domain on Cdc20 for Mad2 and anaphase-promoting complex: model for spindle checkpoint regulation |
Q78103256 | Identification of frequent impairment of the mitotic checkpoint and molecular analysis of the mitotic checkpoint genes, hsMAD2 and p55CDC, in human lung cancers |
Q33924502 | Identification of genes potentially involved in LMO2-induced leukemogenesis |
Q27931376 | Identification of protein complexes required for efficient sister chromatid cohesion |
Q27935697 | Identification of yeast component A: reconstitution of the geranylgeranyltransferase that modifies Ypt1p and Sec4p |
Q36254875 | Impact of HTLV-I Tax on cell cycle progression and the cellular DNA damage repair response |
Q28595006 | Impaired mitotic progression and preimplantation lethality in mice lacking OMCG1, a new evolutionarily conserved nuclear protein |
Q24291921 | Impairment of MAD2B-PRCC interaction in mitotic checkpoint defective t(X;1)-positive renal cell carcinomas |
Q36239496 | In vivo inhibition of cyclin B degradation and induction of cell-cycle arrest in mammalian cells by the neutral cysteine protease inhibitor N-acetylleucylleucylnorleucinal |
Q28593938 | Inactivating the spindle checkpoint kinase Bub1 during embryonic development results in a global shutdown of proliferation |
Q41975129 | Inactivation of a Cdk2 inhibitor during interleukin 2-induced proliferation of human T lymphocytes |
Q34733119 | Inducing precocious anaphase in cultured mammalian cells |
Q40876361 | Infrequent mutation of the hBUB1 and hBUBR1 genes in human lung cancer |
Q24291451 | Inhibition of Cdh1-APC by the MAD2-related protein MAD2L2: a novel mechanism for regulating Cdh1 |
Q34602644 | Integrating functions at the kinetochore |
Q27935628 | Interactions between Centromere Complexes inSaccharomyces cerevisiae |
Q42949353 | Interactions between Mad1p and the nuclear transport machinery in the yeast Saccharomyces cerevisiae |
Q41201215 | Interrogation of γ-tubulin alleles using high-resolution fitness measurements reveals a distinct cytoplasmic function in spindle alignment |
Q27939198 | Ipl1p-dependent phosphorylation of Mad3p is required for the spindle checkpoint response to lack of tension at kinetochores. |
Q27934486 | Isolation and characterization of chromosome-gain and increase-in-ploidy mutants in yeast. |
Q42580772 | Isolation of a Schizosaccharomyces pombe rad21ts mutant that is aberrant in chromosome segregation, microtubule function, DNA repair and sensitive to hydroxyurea: possible involvement of Rad21 in ubiquitin-mediated proteolysis. |
Q52957887 | Isolation of a spontaneous cerulenin-resistant sake yeast with both high ethyl caproate-producing ability and normal checkpoint integrity. |
Q33965797 | Isolation of mutants of Saccharomyces cerevisiae requiring DNA topoisomerase I. |
Q37349399 | Key players in chromosome segregation in Caenorhabditis elegans |
Q35081235 | Kinesin family member 4A: a potential predictor for progression of human oral cancer |
Q27932374 | Kinesin-related proteins required for assembly of the mitotic spindle |
Q30305838 | Kinetochore "memory" of spindle checkpoint signaling in lysed mitotic cells |
Q30442219 | Kinetochore chemistry is sensitive to tension and may link mitotic forces to a cell cycle checkpoint |
Q29618221 | Kinetochore localization of murine Bub1 is required for normal mitotic timing and checkpoint response to spindle damage |
Q30448761 | Kinetochore localization of spindle checkpoint proteins: who controls whom? |
Q34298395 | Kinetochore motility after severing between sister centromeres using laser microsurgery: Evidence that kinetochore directional instability and position is regulated by tension |
Q37598776 | Kinetochore targeting of fission yeast Mad and Bub proteins is essential for spindle checkpoint function but not for all chromosome segregation roles of Bub1p |
Q30312214 | Kinetochores, microtubules and the metaphase checkpoint |
Q30483272 | Latrunculin A delays anaphase onset in fission yeast by disrupting an Ase1-independent pathway controlling mitotic spindle stability |
Q24548054 | Lesions in many different spindle components activate the spindle checkpoint in the budding yeast Saccharomyces cerevisiae |
Q30476312 | Live imaging of Drosophila brain neuroblasts reveals a role for Lis1/dynactin in spindle assembly and mitotic checkpoint control |
Q29620330 | Localization of Mad2 to kinetochores depends on microtubule attachment, not tension |
Q45040800 | Localization of mitotic arrest deficient 1 (MAD1) in mouse oocytes during the first meiosis and its functions as a spindle checkpoint protein |
Q39456488 | Loss of a protein phosphatase 2A regulatory subunit (Cdc55p) elicits improper regulation of Swe1p degradation |
Q27334868 | Loss of function of the Cik1/Kar3 motor complex results in chromosomes with syntelic attachment that are sensed by the tension checkpoint |
Q37264051 | Loss of spindle assembly checkpoint-mediated inhibition of Cdc20 promotes tumorigenesis in mice |
Q55308042 | MAD1: Kinetochore Receptors and Catalytic Mechanisms. |
Q24648493 | MAD2 associates with the cyclosome/anaphase-promoting complex and inhibits its activity |
Q27935794 | MAD3 encodes a novel component of the spindle checkpoint which interacts with Bub3p, Cdc20p, and Mad2p |
Q59061245 | Mad Bet for Rab |
Q24672331 | Mad1p, a phosphoprotein component of the spindle assembly checkpoint in budding yeast |
Q34168724 | Mad2 and BubR1 function in a single checkpoint pathway that responds to a loss of tension. |
Q35751334 | Mad2 and Mad3 cooperate to arrest budding yeast in mitosis |
Q36178158 | Mad2 and p27 expression profiles in colorectal cancer and its clinical significance |
Q36309195 | Mad2 and p53 expression profiles in colorectal cancer and its clinical significance |
Q36289100 | Mad2 and the APC/C compete for the same site on Cdc20 to ensure proper chromosome segregation |
Q24534571 | Mad2 binding to Mad1 and Cdc20, rather than oligomerization, is required for the spindle checkpoint |
Q34708764 | Mad2 haploinsufficiency protects hematopoietic progenitor cells subjected to cell-cycle stress in vivo and to inhibition of redox function of Ape1/Ref-1 in vitro |
Q35642838 | Mad2 is required for optimal hematopoiesis: Mad2 associates with c-Kit in MO7e cells |
Q24682864 | Mad2 transiently associates with an APC/p55Cdc complex during mitosis |
Q34166856 | Mad2, Bub3, and Mps1 regulate chromosome segregation and mitotic synchrony in Giardia intestinalis, a binucleate protist lacking an anaphase-promoting complex. |
Q34101240 | Mad2-Independent inhibition of APCCdc20 by the mitotic checkpoint protein BubR1. |
Q41843920 | Mad2-independent spindle assembly checkpoint activation and controlled metaphase-anaphase transition in Drosophila S2 cells. |
Q24635263 | Mammalian mad2 and bub1/bubR1 recognize distinct spindle-attachment and kinetochore-tension checkpoints |
Q37033768 | Meiosis in oocytes: predisposition to aneuploidy and its increased incidence with age. |
Q37371435 | Meiotic recombination and the crossover assurance checkpoint in Caenorhabditis elegans |
Q49068196 | Metaphase arrest in newly matured or microtubule-depleted mouse eggs after calcium stimulation. |
Q41824169 | Metaphase arrest with centromere separation in polo mutants of Drosophila |
Q30442107 | Microinjection of antibody to Mad2 protein into mammalian cells in mitosis induces premature anaphase |
Q30442229 | Microinjection of mitotic cells with the 3F3/2 anti-phosphoepitope antibody delays the onset of anaphase |
Q38069082 | Microtubule attachment and spindle assembly checkpoint signalling at the kinetochore |
Q24679267 | Microtubule capture by CENP-E silences BubR1-dependent mitotic checkpoint signaling |
Q36234789 | Microtubule dependency of p34cdc2 inactivation and mitotic exit in mammalian cells |
Q34451728 | Microtubule stability in budding yeast: characterization and dosage suppression of a benomyl-dependent tubulin mutant |
Q34368625 | Microtubule-associated proteins and their essential roles during mitosis. |
Q34123562 | Mitosis: a history of division |
Q41312009 | Mitosis: don't get mad, get even |
Q40352474 | Mitotic DNA damage and replication checkpoints in yeast |
Q42254103 | Mitotic Kinases and p53 Signaling |
Q42180607 | Mitotic arrest deficiency 2 induces carcinogenesis in mucinous ovarian tumors |
Q37971550 | Mitotic checkpoint control and chromatin remodeling. |
Q37619395 | Mitotic checkpoint function in the formation of gross chromosomal rearrangements in Saccharomyces cerevisiae |
Q52536019 | Mitotic checkpoint inactivation fosters transformation in cells lacking the breast cancer susceptibility gene, Brca2. |
Q55171502 | Mitotic checkpoint protein hsMAD2 as a marker predicting liver metastasis of human gastric cancers. |
Q35228797 | Mitotic checkpoints |
Q33926467 | Mitotic chromosomal instability and cancer: mouse modelling of the human disease. |
Q36370029 | Mitotic spindle integrity and kinetochore function linked by the Duo1p/Dam1p complex |
Q37778008 | Molecular Mechanisms and Function of the Spindle Checkpoint, a Guardian of the Chromosome Stability |
Q46889398 | Molecular Mechanisms of Spindle Assembly Checkpoint Activation and Silencing |
Q37279001 | Molecular alterations associated with bladder cancer initiation and progression |
Q40799396 | Molecular analyses of the mitotic checkpoint components hsMAD2, hBUB1 and hBUB3 in human cancer |
Q55034501 | Molecular analysis of the mitotic checkpoint genes BUB1, BUBR1 and BUB3 in human lung cancers. |
Q30810456 | Molecular basis of APC/C regulation by the spindle assembly checkpoint |
Q28202760 | Molecular cloning and characterization of the human budding uninhibited by benomyl (BUB3) promoter |
Q37000269 | Molecular mechanisms underlying the MiT translocation subgroup of renal cell carcinomas |
Q37818590 | Monitoring spindle orientation: Spindle position checkpoint in charge. |
Q40852235 | Mos and the cell cycle: the molecular basis of the transformed phenotype |
Q34154624 | Motility proteins and the origin of the nucleus |
Q43680754 | Mps1 is a kinetochore-associated kinase essential for the vertebrate mitotic checkpoint. |
Q52740155 | Mps1 promotes chromosome meiotic chromosome bi-orientation through Dam1. |
Q35925170 | Mps1Mph1 Kinase Phosphorylates Mad3 to Inhibit Cdc20Slp1-APC/C and Maintain Spindle Checkpoint Arrests |
Q48503928 | Multiple Duties for Spindle Assembly Checkpoint Kinases in Meiosis. |
Q30591637 | Multiple mechanisms determine the order of APC/C substrate degradation in mitosis |
Q40944054 | Mutation analysis of hBUB1 in aneuploid HNSCC and lung cancer cell lines |
Q55239937 | Mutation analysis of mitotic checkpoint genes (hBUB1 and hBUBR1) and microsatellite instability in adult T-cell leukemia/lymphoma. |
Q30326722 | Mutation and expression analysis of human BUB1 and BUB1B in aneuploid breast cancer cell lines. |
Q33961348 | Mutation in the bimD gene of Aspergillus nidulans confers a conditional mitotic block and sensitivity to DNA damaging agents |
Q27934947 | Mutation of YCS4, a budding yeast condensin subunit, affects mitotic and nonmitotic chromosome behavior. |
Q52536820 | Mutational inactivation of mitotic checkpoint genes, hsMAD2 and hBUB1, is rare in sporadic digestive tract cancers. |
Q33964830 | Mutations affecting donor preference during mating type interconversion in Saccharomyces cerevisiae |
Q39687193 | Mutations in genes of Saccharomyces cerevisiae encoding pre-mRNA splicing factors cause cell cycle arrest through activation of the spindle checkpoint |
Q36382112 | Mutations in the essential spindle checkpoint gene bub1 cause chromosome missegregation and fail to block apoptosis in Drosophila |
Q24320018 | Mutations of mitotic checkpoint genes in human cancers |
Q74247121 | Mutations of the CDC28 gene and the radiation sensitivity of Saccharomyces cerevisiae |
Q27931536 | NAP1 acts with Clb1 to perform mitotic functions and to suppress polar bud growth in budding yeast |
Q24310671 | NEK2A interacts with MAD1 and possibly functions as a novel integrator of the spindle checkpoint signaling |
Q36864195 | New alleles of the yeast MPS1 gene reveal multiple requirements in spindle pole body duplication |
Q67785116 | New nucleotide sequence data on the EMBL File Server |
Q27932226 | New yeast genes important for chromosome integrity and segregation identified by dosage effects on genome stability. |
Q36559708 | Novel checkpoint pathway organization promotes genome stability in stationary-phase yeast cells |
Q42144842 | Novel mad2 alleles isolated in a Schizosaccharomyces pombe gamma-tubulin mutant are defective in metaphase arrest activity, but remain functional for chromosome stability in unperturbed mitosis |
Q37725706 | Nuclear transport and the mitotic apparatus: an evolving relationship |
Q34455685 | Nup2 requires a highly divergent partner, NupA, to fulfill functions at nuclear pore complexes and the mitotic chromatin region |
Q29619455 | On the road to cancer: aneuploidy and the mitotic checkpoint |
Q39877190 | Oncogenic Adenomatous polyposis coli mutants impair the mitotic checkpoint through direct interaction with Mad2. |
Q36235409 | Oocyte activation and passage through the metaphase/anaphase transition of the meiotic cell cycle is blocked in clams by inhibitors of HMG-CoA reductase activity |
Q27335480 | Overlap microtubules link sister k-fibres and balance the forces on bi-oriented kinetochores. |
Q36149288 | PRP4 is a spindle assembly checkpoint protein required for MPS1, MAD1, and MAD2 localization to the kinetochores |
Q35133777 | Pds1/Esp1-dependent and -independent sister chromatid separation in mutants defective for protein phosphatase 2A. |
Q34375310 | Pds1p, an inhibitor of anaphase in budding yeast, plays a critical role in the APC and checkpoint pathway(s). |
Q41381141 | Phenotypic Diagnosis of Lineage and Differentiation During Sake Yeast Breeding. |
Q45057829 | Phenyl hydroquinone, an Ames test-negative carcinogen, induces Hog1-dependent stress response signaling |
Q27932398 | Phospholipase C is involved in kinetochore function in Saccharomyces cerevisiae |
Q43799855 | Phosphorylation of gamma-tubulin regulates microtubule organization in budding yeast |
Q22009360 | Phosphorylation of human MAD1 by the BUB1 kinase in vitro |
Q28478060 | Phosphorylation of the yeast γ-tubulin Tub4 regulates microtubule function |
Q36532077 | Poleward kinetochore fiber movement occurs during both metaphase and anaphase-A in newt lung cell mitosis |
Q30496569 | Polo kinase interacts with RacGAP50C and is required to localize the cytokinesis initiation complex. |
Q33829619 | Polyploidy: occurrence in nature, mechanisms, and significance for the megakaryocyte-platelet system |
Q93348582 | Posing the APC/C E3 Ubiquitin Ligase to Orchestrate Cell Division |
Q41558814 | Positive Feedback Keeps Duration of Mitosis Temporally Insulated from Upstream Cell-Cycle Events |
Q24685871 | Probing spindle assembly mechanisms with monastrol, a small molecule inhibitor of the mitotic kinesin, Eg5. |
Q28214604 | Probing the dynamics and functions of aurora B kinase in living cells during mitosis and cytokinesis |
Q37247590 | Profile of Andrew W. Murray |
Q39038787 | Proline-rich acidic protein 1 (PRAP1) is a novel interacting partner of MAD1 and has a suppressive role in mitotic checkpoint signalling in hepatocellular carcinoma |
Q24304123 | Prophase destruction of Emi1 by the SCF(betaTrCP/Slimb) ubiquitin ligase activates the anaphase promoting complex to allow progression beyond prometaphase |
Q52724818 | Protein arginine methylation: an emerging regulator of the cell cycle. |
Q46108071 | Protein phosphatase 2A regulates MPF activity and sister chromatid cohesion in budding yeast |
Q40746403 | Protein prenylation in eukaryotic microorganisms: genetics, biology and biochemistry |
Q88875566 | Purification of kinetochores from the budding yeast Saccharomyces cerevisiae |
Q33969321 | RAD9, RAD17, and RAD24 are required for S phase regulation in Saccharomyces cerevisiae in response to DNA damage. |
Q47770267 | Radiosensitivity and oxidative signalling in ataxia telangiectasia: an update |
Q24299702 | Re-evaluating the role of Tao1 in the spindle checkpoint |
Q64058303 | Recent Progress on the Localization of the Spindle Assembly Checkpoint Machinery to Kinetochores |
Q27936495 | Receptors determine the cellular localization of a gamma-tubulin complex and thereby the site of microtubule formation |
Q30452748 | Recognizing chromosomes in trouble: association of the spindle checkpoint protein Bub3p with altered kinetochores and a unique defective centromere |
Q34040203 | Recruitment of Mad1 to metaphase kinetochores is sufficient to reactivate the mitotic checkpoint. |
Q35102601 | Reduced Mad2 expression keeps relaxed kinetochores from arresting budding yeast in mitosis |
Q57028061 | Regulated reconstitution of spindle checkpoint arrest and silencing through chemically induced dimerisation |
Q28216974 | Regulation of APC-Cdc20 by the spindle checkpoint |
Q33805690 | Regulation of APC/C activators in mitosis and meiosis |
Q34010063 | Regulation of Cdc28 cyclin-dependent protein kinase activity during the cell cycle of the yeast Saccharomyces cerevisiae. |
Q92106577 | Regulation of Cell Cycle Entry and Exit: A Single Cell Perspective |
Q89719971 | Regulation of Mitotic Exit by Cell Cycle Checkpoints: Lessons From Saccharomyces cerevisiae |
Q27931654 | Regulation of Saccharomyces cerevisiae kinetochores by the type 1 phosphatase Glc7p |
Q37035104 | Regulation of kinetochore recruitment of two essential mitotic spindle checkpoint proteins by Mps1 phosphorylation |
Q38496747 | Regulation of the Bub2/Bfa1 GAP complex by Cdc5 and cell cycle checkpoints. |
Q34720135 | Regulation of the cell cycle by protein phosphatase 2A in Saccharomyces cerevisiae |
Q38612159 | Regulation of the cyclin B degradation system by an inhibitor of mitotic proteolysis |
Q33816797 | Removal of Spindly from microtubule-attached kinetochores controls spindle checkpoint silencing in human cells |
Q24657489 | Requirement for ESP1 in the nuclear division of Saccharomyces cerevisiae |
Q57009269 | Requirement of Chromatid Cohesion Proteins Rad21/Scc1 and Mis4/Scc2 for Normal Spindle-Kinetochore Interaction in Fission Yeast |
Q27935461 | Requirement of Skp1-Bub1 interaction for kinetochore-mediated activation of the spindle checkpoint |
Q35552257 | Retention of the BUB3 checkpoint protein on lagging chromosomes |
Q21562380 | Reverse engineering of the spindle assembly checkpoint |
Q27303046 | Ribonuclease activity of Dis3 is required for mitotic progression and provides a possible link between heterochromatin and kinetochore function |
Q27932711 | Rmi1, a member of the Sgs1-Top3 complex in budding yeast, contributes to sister chromatid cohesion |
Q35822970 | Role of BRCA1 in controlling mitotic arrest in ovarian cystadenoma cells |
Q27940146 | Role of calmodulin and Spc110p interaction in the proper assembly of spindle pole body compenents |
Q89394572 | Role of the BUB3 protein in phragmoplast microtubule reorganization during cytokinesis |
Q43037807 | Rong Li: tipping the balance in cell biology. Interview by Caitlin Sedwick |
Q36123872 | SAC-ing mitotic errors: how the spindle assembly checkpoint (SAC) plays defense against chromosome mis-segregation |
Q30484120 | SPDL-1 functions as a kinetochore receptor for MDF-1 in Caenorhabditis elegans |
Q33963575 | SPO13 negatively regulates the progression of mitotic and meiotic nuclear division in Saccharomyces cerevisiae |
Q42147135 | Saccharomyces CDK1 phosphorylates Rad53 kinase in metaphase, influencing cellular morphogenesis |
Q64389726 | Saccharomyces cerevisiae cells lacking the homologous pairing protein p175SEP1 arrest at pachytene during meiotic prophase |
Q27931214 | Saccharomyces cerevisiae cells with defective spindle pole body outer plaques accomplish nuclear migration via half-bridge-organized microtubules |
Q27931564 | Saccharomyces cerevisiae genes required in the absence of the CIN8-encoded spindle motor act in functionally diverse mitotic pathways |
Q73270846 | Search for in vivo somatic mutations in the mitotic checkpoint gene, hMAD1, in human lung cancers |
Q36555047 | Segregation of unreplicated chromosomes in Saccharomyces cerevisiae reveals a novel G1/M-phase checkpoint |
Q33594202 | Separating sister chromatids |
Q48065169 | Sequence of ptb1, a gene for the beta subunit of the type-II geranylgeranyltransferase from the fission yeast Schizosaccharomyces pombe |
Q27939072 | Sfh1p, a component of a novel chromatin-remodeling complex, is required for cell cycle progression |
Q38258850 | Signalling dynamics in the spindle checkpoint response |
Q24530007 | Sil phosphorylation in a Pin1 binding domain affects the duration of the spindle checkpoint |
Q35773951 | Single-Cell Based Quantitative Assay of Chromosome Transmission Fidelity |
Q42673791 | Sister chromatid separation and chromosome re-duplication are regulated by different mechanisms in response to spindle damage |
Q35033329 | Small molecules, big impact: a history of chemical inhibitors and the cytoskeleton |
Q35019961 | Spatial regulation of the spindle assembly checkpoint and anaphase-promoting complex in Aspergillus nidulans |
Q38588713 | Spatial rule-based modeling: a method and its application to the human mitotic kinetochore |
Q38611058 | Spc98p directs the yeast gamma-tubulin complex into the nucleus and is subject to cell cycle-dependent phosphorylation on the nuclear side of the spindle pole body |
Q24676152 | Specific association of estrogen receptor beta with the cell cycle spindle assembly checkpoint protein, MAD2 |
Q79291199 | Spindle Checkpoint Component Mad2 Contributes to Biorientation of Homologous Chromosomes |
Q58798794 | Spindle Dynamics Model Explains Chromosome Loss Rates in Yeast Polyploid Cells |
Q44052102 | Spindle assembly checkpoint component CaMad2p is indispensable for Candida albicans survival and virulence in mice |
Q36570686 | Spindle assembly checkpoint gene mdf-1 regulates germ cell proliferation in response to nutrition signals in C. elegans |
Q30497012 | Spindle assembly checkpoint genes reveal distinct as well as overlapping expression that implicates MDF-2/Mad2 in postembryonic seam cell proliferation in Caenorhabditis elegans |
Q33497326 | Spindle assembly checkpoint protein dynamics reveal conserved and unsuspected roles in plant cell division |
Q28478743 | Spindle assembly checkpoint regulates mitotic cell cycle progression during preimplantation embryo development |
Q37956287 | Spindle assembly checkpoint: the third decade |
Q36685486 | Spindle checkpoint function and cellular sensitivity to antimitotic drugs |
Q53628480 | Spindle checkpoint function requires Mad2-dependent Cdc20 binding to the Mad3 homology domain of BubR1. |
Q40322565 | Spindle checkpoint protein Bub1 corrects mitotic aberrancy induced by human T-cell leukemia virus type I Tax. |
Q24679269 | Spindle checkpoint protein Bub1 is required for kinetochore localization of Mad1, Mad2, Bub3, and CENP-E, independently of its kinase activity |
Q24682946 | Spindle checkpoint protein Xmad1 recruits Xmad2 to unattached kinetochores |
Q36321836 | Spindle checkpoint proteins and chromosome-microtubule attachment in budding yeast |
Q34510907 | Spindle checkpoint regulates Cdc20p stability in Saccharomyces cerevisiae |
Q30431071 | Spindle poisons and cell fate: a tale of two pathways. |
Q35647368 | Spindles, mitochondria and redox potential in ageing oocytes |
Q39859976 | Spo13 protects meiotic cohesin at centromeres in meiosis I. |
Q30858730 | Spotlite: web application and augmented algorithms for predicting co-complexed proteins from affinity purification--mass spectrometry data. |
Q47807712 | Stochastic Modeling Yields a Mechanistic Framework for Spindle Attachment Error Correction in Budding Yeast Mitosis. |
Q41345432 | Stopping and starting the meiotic cell cycle |
Q24305233 | Structural analysis reveals features of the spindle checkpoint kinase Bub1-kinetochore subunit Knl1 interaction |
Q27653321 | Structural and mechanistic insights into Mps1 kinase activation |
Q34283356 | Structural maintenance of chromosome (SMC) proteins link microtubule stability to genome integrity |
Q30497439 | Structure of the anaphase-promoting complex/cyclosome interacting with a mitotic checkpoint complex |
Q27678130 | Structure of the mitotic checkpoint complex |
Q35564845 | Structure, Function, and Regulation of Budding Yeast Kinetochores |
Q36316609 | Stu2 promotes mitotic spindle elongation in anaphase. |
Q50643285 | Studying Kinetochores In Vivo Using FLIM-FRET. |
Q37148422 | Suppression of genomic instabilities caused by chromosome mis-segregation: a perspective from studying BubR1 and Sgo1. |
Q36232176 | Suppression of the bimC4 mitotic spindle defect by deletion of klpA, a gene encoding a KAR3-related kinesin-like protein in Aspergillus nidulans |
Q40241760 | Suppression of yeast geranylgeranyl transferase I defect by alternative prenylation of two target GTPases, Rho1p and Cdc42p |
Q35757666 | Suppressors of spindle checkpoint defect (such) mutants identify new mdf-1/MAD1 interactors in Caenorhabditis elegans |
Q40366333 | Symmetric cell division in pseudohyphae of the yeast Saccharomyces cerevisiae |
Q37544007 | Synthetic genetic array screen identifies PP2A as a therapeutic target in Mad2-overexpressing tumors |
Q42986632 | Synthetic lethal interactions identify phenotypic "interologs" of the spindle assembly checkpoint components |
Q30485999 | Systematic analysis in Caenorhabditis elegans reveals that the spindle checkpoint is composed of two largely independent branches |
Q40454087 | Systems Biology Modeling of Five Pathways for Regulation and Potent Inhibition of the Anaphase-Promoting Complex (APC/C): Pivotal Roles for MCC and BubR1. |
Q40242633 | TPR proteins required for anaphase progression mediate ubiquitination of mitotic B-type cyclins in yeast |
Q40381344 | Tension sensing by Aurora B kinase is independent of survivin-based centromere localization. |
Q35220804 | Tethering sister centromeres to each other suggests the spindle checkpoint detects stretch within the kinetochore |
Q45985430 | The 1.1-angstrom structure of the spindle checkpoint protein Bub3p reveals functional regions. |
Q27931517 | The 14-3-3 protein Bmh1 functions in the spindle position checkpoint by breaking Bfa1 asymmetry at yeast centrosomes |
Q33565078 | The A78V mutation in the Mad3-like domain of Schizosaccharomyces pombe Bub1p perturbs nuclear accumulation and kinetochore targeting of Bub1p, Bub3p, and Mad3p and spindle assembly checkpoint function |
Q34166850 | The ARF tumor suppressor prevents chromosomal instability and ensures mitotic checkpoint fidelity through regulation of Aurora B. |
Q34069561 | The ATM-p53 pathway suppresses aneuploidy-induced tumorigenesis |
Q74191133 | The Bub2p spindle checkpoint links nuclear migration with mitotic exit |
Q41716201 | The C-terminal domains of human neurofibromin and its budding yeast homologs Ira1 and Ira2 regulate the metaphase to anaphase transition |
Q27938665 | The C-terminal half of Saccharomyces cerevisiae Mad1p mediates spindle checkpoint function, chromosome transmission fidelity and CEN association |
Q28756446 | The Drosophila cell cycle gene fizzy is required for normal degradation of cyclins A and B during mitosis and has homology to the CDC20 gene of Saccharomyces cerevisiae |
Q36531724 | The Drosophila l(1)zw10 gene product, required for accurate mitotic chromosome segregation, is redistributed at anaphase onset |
Q27931658 | The JNM1 gene in the yeast Saccharomyces cerevisiae is required for nuclear migration and spindle orientation during the mitotic cell cycle |
Q61735093 | The Kinetochore of Higher Eucaryotes: A Molecular View |
Q24611018 | The Lrs4-Csm1 monopolin complex associates with kinetochores during anaphase and is required for accurate chromosome segregation |
Q34585694 | The Mub1/Ubr2 ubiquitin ligase complex regulates the conserved Dsn1 kinetochore protein |
Q21145727 | The Oxytricha trifallax macronuclear genome: a complex eukaryotic genome with 16,000 tiny chromosomes |
Q29620201 | The Polo-like kinase Cdc5p and the WD-repeat protein Cdc20p/fizzy are regulators and substrates of the anaphase promoting complex in Saccharomyces cerevisiae |
Q47135529 | The Power of Xenopus Egg Extract for Reconstitution of Centromere and Kinetochore Function. |
Q27940101 | The Rho-GEF Rom2p localizes to sites of polarized cell growth and participates in cytoskeletal functions in Saccharomyces cerevisiae |
Q34618699 | The Role of Cdh1p in Maintaining Genomic Stability in Budding Yeast |
Q34054674 | The S. pombe cdc16 gene is required both for maintenance of p34cdc2 kinase activity and regulation of septum formation: a link between mitosis and cytokinesis? |
Q24607689 | The Saccharomyces cerevisiae checkpoint gene BUB1 encodes a novel protein kinase |
Q42837122 | The Saccharomyces cerevisiae kinesin-related motor Kar3p acts at preanaphase spindle poles to limit the number and length of cytoplasmic microtubules |
Q27939738 | The Saccharomyces cerevisiae spindle pole body duplication gene MPS1 is part of a mitotic checkpoint |
Q24683919 | The Schizosaccharomyces pombe spindle checkpoint protein mad2p blocks anaphase and genetically interacts with the anaphase-promoting complex |
Q33195000 | The Spindle Assembly and Spindle Position Checkpoints |
Q39939839 | The ability to survive mitosis in the presence of microtubule poisons differs significantly between human nontransformed (RPE-1) and cancer (U2OS, HeLa) cells |
Q34354307 | The art and design of genetic screens: yeast |
Q35164326 | The biochemistry of mitosis |
Q27931138 | The budding yeast Cdc48(Shp1) complex promotes cell cycle progression by positive regulation of protein phosphatase 1 (Glc7). |
Q28365645 | The budding yeast protein kinase Ipl1/Aurora allows the absence of tension to activate the spindle checkpoint |
Q36335566 | The budding yeast silencing protein Sir1 is a functional component of centromeric chromatin. |
Q27938729 | The calcium-binding protein cell division cycle 31 of Saccharomyces cerevisiae is a component of the half bridge of the spindle pole body |
Q24601346 | The checkpoint protein MAD2 and the mitotic regulator CDC20 form a ternary complex with the anaphase-promoting complex to control anaphase initiation |
Q51121163 | The chk1 pathway is required to prevent mitosis following cell-cycle arrest at 'start'. |
Q37052271 | The classical nuclear localization signal receptor, importin-alpha, is required for efficient transition through the G1/S stage of the cell cycle in Saccharomyces cerevisiae |
Q37063126 | The composition, functions, and regulation of the budding yeast kinetochore |
Q27937537 | The conserved protein kinase Ipl1 regulates microtubule binding to kinetochores in budding yeast |
Q27000924 | The current view for the silencing of the spindle assembly checkpoint |
Q89649028 | The evolutionary plasticity of chromosome metabolism allows adaptation to constitutive DNA replication stress |
Q33255128 | The fission yeast DNA structure checkpoint protein Rad26ATRIP/LCD1/UVSD accumulates in the cytoplasm following microtubule destabilization |
Q35916037 | The fission yeast dma1 gene is a component of the spindle assembly checkpoint, required to prevent septum formation and premature exit from mitosis if spindle function is compromised |
Q40388135 | The fission yeast gamma-tubulin complex is required in G(1) phase and is a component of the spindle assembly checkpoint |
Q30477171 | The fission yeast transforming acidic coiled coil-related protein Mia1p/Alp7p is required for formation and maintenance of persistent microtubule-organizing centers at the nuclear envelope. |
Q33467385 | The function of a spindle checkpoint gene bub-1 in C. elegans development |
Q40873279 | The gene as theme in the paradigm of cancer |
Q40525099 | The genetics of cell cycle checkpoints |
Q30310388 | The highly conserved Ndc80 complex is required for kinetochore assembly, chromosome congression, and spindle checkpoint activity |
Q24314385 | The human homologue of Bub3 is required for kinetochore localization of Bub1 and a Mad3/Bub1-related protein kinase |
Q24306626 | The human spindle assembly checkpoint protein Bub3 is required for the establishment of efficient kinetochore-microtubule attachments |
Q34739115 | The interaction between Ran and NTF2 is required for cell cycle progression |
Q37294890 | The interplay between chromosome stability and cell cycle control explored through gene-gene interaction and computational simulation |
Q30856850 | The kinetochore protein Ndc10p is required for spindle stability and cytokinesis in yeast. |
Q30442066 | The maize homologue of the cell cycle checkpoint protein MAD2 reveals kinetochore substructure and contrasting mitotic and meiotic localization patterns |
Q34060695 | The metaphase II arrest in mouse oocytes is controlled through microtubule-dependent destruction of cyclin B in the presence of CSF. |
Q33700992 | The metaphase to anaphase transition: a case of productive destruction |
Q41678505 | The metaphase-to-anaphase transition: avoiding a mid-life crisis |
Q41146841 | The mitotic checkpoint complex (MCC): looking back and forth after 15 years |
Q28188970 | The mitotic checkpoint protein hBUB3 and the mRNA export factor hRAE1 interact with GLE2p-binding sequence (GLEBS)-containing proteins |
Q27933128 | The mitotic feedback control gene MAD2 encodes the alpha-subunit of a prenyltransferase |
Q35004928 | The mitotic spindle is required for loading of the DASH complex onto the kinetochore |
Q42827088 | The mouse Mps1p-like kinase regulates centrosome duplication |
Q37467150 | The nature of cell-cycle checkpoints: facts and fallacies |
Q35013042 | The property of DNA polymerase zeta: REV7 is a putative protein involved in translesion DNA synthesis and cell cycle control |
Q27938593 | The protein phosphatase 2A functions in the spindle position checkpoint by regulating the checkpoint kinase Kin4 |
Q24645774 | The rRNA-processing function of the yeast U14 small nucleolar RNA can be rescued by a conserved RNA helicase-like protein |
Q37037122 | The rad3+ gene of Schizosaccharomyces pombe is involved in multiple checkpoint functions and in DNA repair |
Q41193565 | The role of DNA repair in the prevention of cancer |
Q48074421 | The role of Saccharomyces cerevisiae Cdc40p in DNA replication and mitotic spindle formation and/or maintenance |
Q36333350 | The role of centromere-binding factor 3 (CBF3) in spindle stability, cytokinesis, and kinetochore attachment. |
Q35622956 | The role of mitotic checkpoint in maintaining genomic stability |
Q27935576 | The roles of MAD1, MAD2 and MAD3 in meiotic progression and the segregation of nonexchange chromosomes |
Q45044181 | The scaffolding A/Tpd3 subunit and high phosphatase activity are dispensable for Cdc55 function in the Saccharomyces cerevisiae spindle checkpoint and in cytokinesis |
Q37421316 | The signaling network that silences the spindle assembly checkpoint upon the establishment of chromosome bipolar attachment |
Q41239083 | The spindle assembly checkpoint |
Q37306927 | The spindle assembly checkpoint in Caenorhabditis elegans: one who lacks Mad1 becomes mad one |
Q46317065 | The spindle assembly checkpoint in budding yeast |
Q36322881 | The spindle assembly checkpoint is not essential for CSF arrest of mouse oocytes |
Q41076740 | The spindle assembly checkpoint regulates the phosphorylation state of a subset of DNA checkpoint proteins in Saccharomyces cerevisiae |
Q30557537 | The spindle assembly checkpoint works like a rheostat rather than a toggle switch |
Q36456381 | The spindle assembly checkpoint: preventing chromosome mis-segregation during mitosis and meiosis |
Q56951146 | The spindle checkpoint |
Q27932971 | The spindle checkpoint of budding yeast depends on a tight complex between the Mad1 and Mad2 proteins |
Q35160717 | The spindle checkpoint protein Mad2 regulates APC/C activity during prometaphase and metaphase of meiosis I in Saccharomyces cerevisiae |
Q33976673 | The spindle checkpoint, aneuploidy, and cancer |
Q27931883 | The spindle checkpoint. |
Q35853950 | The spindle checkpoint: a quality control mechanism which ensures accurate chromosome segregation |
Q35563514 | The spindle checkpoint: from normal cell division to tumorigenesis. |
Q34931754 | The spindle checkpoint: structural insights into dynamic signalling |
Q30305518 | The spindle checkpoint: two transitions, two pathways |
Q27334674 | The spindle pole bodies facilitate nuclear envelope division during closed mitosis in fission yeast |
Q27860766 | The spindle-assembly checkpoint in space and time |
Q34775279 | The tumor suppressor CDKN3 controls mitosis |
Q28071855 | The unconventional kinetoplastid kinetochore: from discovery toward functional understanding |
Q27936786 | The yeast ULP2 (SMT4) gene encodes a novel protease specific for the ubiquitin-like Smt3 protein |
Q36273872 | The yeast motor protein, Kar3p, is essential for meiosis I |
Q47978899 | Three BUB1 and BUBR1/MAD3-related spindle assembly checkpoint proteins are required for accurate mitosis in Arabidopsis |
Q30450971 | Three-dimensional analysis and ultrastructural design of mitotic spindles from the cdc20 mutant of Saccharomyces cerevisiae |
Q27931369 | Two complexes of spindle checkpoint proteins containing Cdc20 and Mad2 assemble during mitosis independently of the kinetochore in Saccharomyces cerevisiae |
Q33641351 | Two genes required for the binding of an essential Saccharomyces cerevisiae kinetochore complex to DNA. |
Q36657172 | Type 1 protein phosphatase acts in opposition to IpL1 protein kinase in regulating yeast chromosome segregation |
Q74010958 | Uncoupling of the order of the S and M phases: effects of staurosporine on human cell cycle kinases |
Q24541554 | Uncoupling the central spindle-associated function of the chromosomal passenger complex from its role at centromeres |
Q35882315 | Under Tension: Kinetochores and Basic Research |
Q36366483 | Unraveling cell division mechanisms with small-molecule inhibitors |
Q40883498 | Unravelling the tangled web at the microtubule-organizing center |
Q28756062 | Unzipped and loaded: the role of DNA helicases and RFC clamp-loading complexes in sister chromatid cohesion |
Q28253087 | Variation in crossover frequencies perturb crossover assurance without affecting meiotic chromosome segregation in Saccharomyces cerevisiae |
Q36293815 | Visualization of Mad2 dynamics at kinetochores, along spindle fibers, and at spindle poles in living cells |
Q47105112 | Visualizing the complex functions and mechanisms of the anaphase promoting complex/cyclosome (APC/C). |
Q41352428 | When checkpoints fail |
Q40361712 | YND1 interacts with CDC55 and is a novel mediator of E4orf4-induced toxicity |
Q27932982 | Ybp2 associates with the central kinetochore of Saccharomyces cerevisiae and mediates proper mitotic progression |
Q36895837 | Yeast Dam1p is required to maintain spindle integrity during mitosis and interacts with the Mps1p kinase |
Q27934121 | Yeast Rrp14p is required for ribosomal subunit synthesis and for correct positioning of the mitotic spindle during mitosis |
Q36181404 | Yeast as a model system for anticancer drug discovery |
Q24608777 | Yeast cohesin complex requires a conserved protein, Eco1p(Ctf7), to establish cohesion between sister chromatids during DNA replication |
Q24299625 | Zwilch, a new component of the ZW10/ROD complex required for kinetochore functions |
Q77116066 | [When chromosomal dynamics control cell division] |
Q46968710 | beta-Tubulin mutation suppresses microtubule dynamics in vitro and slows mitosis in vivo |
Q33958873 | c-Myc overexpression uncouples DNA replication from mitosis |
Q34044907 | gamma-Tubulin of budding yeast |
Q36237019 | gamma-Tubulin-like Tub4p of Saccharomyces cerevisiae is associated with the spindle pole body substructures that organize microtubules and is required for mitotic spindle formation |
Q74406181 | hBUB1 defects in leukemia and lymphoma cells |
Q35551712 | p31(comet) acts to ensure timely spindle checkpoint silencing subsequent to kinetochore attachment |
Q41438652 | p53 and ATM: cell cycle, cell death, and cancer. |
Q24290396 | p55CDC/hCDC20 is associated with BUBR1 and may be a downstream target of the spindle checkpoint kinase |
Q35746700 | polo Is Identified as a Suppressor of bubR1 Nondisjunction in a Deficiency Screen of the Third Chromosome in Drosophila melanogaster |
Q36821940 | pp39mos is associated with p34cdc2 kinase in c-mosxe-transformed NIH 3T3 cells |
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