| scholarly article | Q13442814 |
| P50 | author | Matthias Gaestel | Q23057692 |
| Alexey Kotlyarov | Q41603274 | ||
| Xavier Preville | Q42316261 | ||
| Catherine Paul | Q50228299 | ||
| P2093 | author name string | J Buchner | |
| A P Arrigo | |||
| C Ducasse | |||
| G Lutsch | |||
| M Wieske | |||
| M Ehrnsperger | |||
| T Rogalla | |||
| P433 | issue | 27 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | molecular chaperones | Q422496 |
| phosphorylation | Q242736 | ||
| P304 | page(s) | 18947-18956 | |
| P577 | publication date | 1999-07-01 | |
| P1433 | published in | Journal of Biological Chemistry | Q867727 |
| P1476 | title | Regulation of Hsp27 oligomerization, chaperone function, and protective activity against oxidative stress/tumor necrosis factor alpha by phosphorylation | |
| P478 | volume | 274 |
| Q34481801 | A Mechanism of Subunit Recruitment in Human Small Heat Shock Protein Oligomers |
| Q47642202 | A Novel Kinase Function of a Nucleoside-diphosphate-kinase Homolog in P. gingivalis is Critical in Subversion of Host Cell Apoptosis by Targeting Heat-Shock Protein 27. |
| Q39313436 | A chemical proteomics approach reveals Hsp27 as a target for proapoptotic clerodane diterpenes |
| Q40070223 | A critical role of tropomyosins in TGF-beta regulation of the actin cytoskeleton and cell motility in epithelial cells |
| Q35178845 | A first line of stress defense: small heat shock proteins and their function in protein homeostasis |
| Q39236179 | A natural antioxidant pine bark extract, Oligopin®, regulates the stress chaperone HSPB1 in human skeletal muscle cells: a proteomics approach. |
| Q47447879 | A phase I dose-escalation study of apatorsen (OGX-427), an antisense inhibitor targeting heat shock protein 27 (Hsp27), in patients with castration-resistant prostate cancer and other advanced cancers |
| Q35096530 | A rit GTPase-p38 mitogen-activated protein kinase survival pathway confers resistance to cellular stress |
| Q38920547 | A single 60-min bout of peristaltic pulse external pneumatic compression transiently upregulates phosphorylated ribosomal protein s6. |
| Q37108786 | AICAR reduces the collagen-stimulated secretion of PDGF-AB and release of soluble CD40 ligand from human platelets: Suppression of HSP27 phosphorylation via p44/p42 MAP kinase. |
| Q42511240 | AKT-dependent HspB1 (Hsp27) activity in epidermal differentiation |
| Q35916602 | AMP-18 facilitates assembly and stabilization of tight junctions to protect the colonic mucosal barrier |
| Q24316319 | ATM activates the pentose phosphate pathway promoting anti-oxidant defence and DNA repair |
| Q34427456 | Abnormal interaction of motor neuropathy-associated mutant HspB8 (Hsp22) forms with the RNA helicase Ddx20 (gemin3). |
| Q35725164 | Acetyl salicylic acid protected against heat stress damage in chicken myocardial cells and may associate with induced Hsp27 expression |
| Q34966102 | Actin cytoskeleton and small heat shock proteins: how do they interact? |
| Q24632768 | Activation and function of the MAPKs and their substrates, the MAPK-activated protein kinases |
| Q37459887 | Activation of gene transcription by heat shock protein 27 may contribute to its neuronal protection |
| Q46542167 | Alpha-crystallin protected axons from optic nerve degeneration after crushing in rats |
| Q33969470 | Alpha-crystallin-type heat shock proteins: socializing minichaperones in the context of a multichaperone network. |
| Q43801044 | An investigation of the neuroprotective effect of lithium in organotypic slice cultures of rat hippocampus exposed to oxygen and glucose deprivation |
| Q46253811 | Analysis of HspB1 (Hsp27) Oligomerization and Phosphorylation Patterns and Its Interaction with Specific Client Polypeptides |
| Q37490484 | Analysis of interactions between domains of a small heat shock protein, Hsp30 of Neurospora crassa |
| Q50723369 | Analysis of properties of small heat shock protein Hsp25 in MAPK-activated protein kinase 2 (MK2)-deficient cells: MK2-dependent insolubilization of Hsp25 oligomers correlates with susceptibility to stress. |
| Q34947228 | Analysis of the dominant effects mediated by wild type or R120G mutant of αB-crystallin (HspB5) towards Hsp27 (HspB1) |
| Q53400964 | Androgen receptor and heat shock protein 27 co-regulate the malignant potential of molecular apocrine breast cancer. |
| Q34626972 | Anthrax lethal toxin disrupts the endothelial permeability barrier through blocking p38 signaling |
| Q39583474 | Apigenin-induced apoptosis of leukemia cells is mediated by a bimodal and differentially regulated residue-specific phosphorylation of heat-shock protein-27. |
| Q37375811 | Apoptosis versus cell differentiation: role of heat shock proteins HSP90, HSP70 and HSP27 |
| Q51541703 | Association of the clusterin gene polymorphisms with type 2 diabetes mellitus |
| Q37061072 | Autoantibodies in the autoimmune disease pemphigus foliaceus induce blistering via p38 mitogen-activated protein kinase-dependent signaling in the skin |
| Q55110690 | Autoantibody Signaling in Pemphigus Vulgaris: Development of an Integrated Model. |
| Q40599695 | Bacterial GroEL-like heat shock protein 60 protects epithelial cells from stress-induced death through activation of ERK and inhibition of caspase 3. |
| Q36069364 | Beyond transcription--new mechanisms for the regulation of molecular chaperones |
| Q33530053 | Bicyclol protects HepG2 cells against D-galactosamine-induced apoptosis through inducing heat shock protein 27 and mitochondria associated pathway |
| Q36957642 | Bu Shen Tiao Chong recipe restores diminished ovary reserve through the BDNF pathway |
| Q28392377 | COPD and levels of Hsp70 (HSPA1A) and Hsp27 (HSPB1) in plasma and lymphocytes among coal workers: a case-control study |
| Q40231216 | Cell signaling pathways to alphaB-crystallin following stresses of the cytoskeleton |
| Q28534605 | Cell stress promotes the association of phosphorylated HspB1 with F-actin |
| Q44406450 | Changes in heat shock protein 27 phosphorylation and immunocontent in response to preconditioning to oxygen and glucose deprivation in organotypic hippocampal cultures. |
| Q22254290 | Chaperone hsp27 inhibits translation during heat shock by binding eIF4G and facilitating dissociation of cap-initiation complexes |
| Q28547194 | Characterization of Mutants of Human Small Heat Shock Protein HspB1 Carrying Replacements in the N-Terminal Domain and Associated with Hereditary Motor Neuron Diseases |
| Q47734624 | Characterization of human small heat shock protein HSPB1 α-crystallin domain localized mutants associated with hereditary motor neuron diseases. |
| Q39358271 | Characterization of the protein ubiquitination response induced by Doxorubicin. |
| Q38248009 | Chronic neuroprotective effects of low concentration lithium on SH-SY5Y cells: possible involvement of stress proteins and gene expression |
| Q37124219 | Clinicopathological and prognostic significance of heat shock protein 27 (HSP27) expression in non-small cell lung cancer: a systematic review and meta-analysis |
| Q46459423 | Co-induction of alphaB-crystallin and MAPKAPK-2 in astrocytes in the penumbra after transient focal cerebral ischemia |
| Q36452803 | Concomitant inhibition of HSP90, its mitochondrial localized homologue TRAP1 and HSP27 by green tea in pancreatic cancer HPAF-II cells |
| Q34451159 | Conformational changes resulting from pseudophosphorylation of mammalian small heat shock proteins--a two-hybrid study |
| Q41210856 | Consequences of Atrial or Ventricular Tachypacing on the Heat Shock Proteins (HSP) level of Expression and Phosphorylation |
| Q50489155 | Constitutive expression of Hsp27 in the rat cochlea. |
| Q33312089 | Correlation between the progressive cytoplasmic expression of a novel small heat shock protein (Hsp16.2) and malignancy in brain tumors |
| Q27666994 | Crystal Structure of R120G Disease Mutant of Human αB-Crystallin Domain Dimer Shows Closure of a Groove |
| Q27679512 | Crystal Structure of an Activated Variant of Small Heat Shock Protein Hsp16.5 |
| Q24318942 | Crystal structures of alpha-crystallin domain dimers of alphaB-crystallin and Hsp20 |
| Q53486800 | Cyclic strain-induced HSP27 phosphorylation modulates actin filaments in airway smooth muscle cells. |
| Q35212825 | Cytoskeletal mechanisms regulating vascular endothelial barrier function in response to acute lung injury |
| Q44971569 | Decrease of Hsp25 protein expression precedes degeneration of motoneurons in ALS-SOD1 mice |
| Q36677507 | Desmin mediates TNF-alpha-induced aggregate formation and intercalated disk reorganization in heart failure. |
| Q48687308 | Differential expression of small heat shock protein 27 (Hsp27) in Ataxia telangiectasia brains |
| Q33187583 | Differential proteomic analysis of the mouse retina: the induction of crystallin proteins by retinal degeneration in the rd1 mouse |
| Q28141722 | Differential regulation of HSP27 oligomerization in tumor cells grown in vitro and in vivo |
| Q37490116 | Distribution, phosphorylation, and activities of Hsp25 in heat-stressed H9c2 myoblasts: a functional link to cytoprotection. |
| Q40079920 | Doxorubicin-induced cardiotoxicity: direct correlation of cardiac fibroblast and H9c2 cell survival and aconitase activity with heat shock protein 27. |
| Q43127461 | Dynamic processes that reflect anti-apoptotic strategies set up by HspB1 (Hsp27). |
| Q33460724 | Dysregulation of heat shock protein 27 expression in oral tongue squamous cell carcinoma |
| Q29615216 | ERK and p38 MAPK-activated protein kinases: a family of protein kinases with diverse biological functions |
| Q36375609 | Effect of N-terminal region of nuclear Drosophila melanogaster small heat shock protein DmHsp27 on function and quaternary structure. |
| Q53985915 | Effects of global cerebral ischemia and preconditioning on heat shock protein 27 immunocontent and phosphorylation in rat hippocampus. |
| Q33845105 | Effects of p38 MAPK inhibition on early stages of diabetic retinopathy and sensory nerve function |
| Q37488978 | Effects of rosiglitazone on heat shock protein and the endothelin system in deoxycorticosterone acetate-salt hypertensive rats |
| Q35470183 | Elevated expression of long intergenic non-coding RNA HOTAIR in a basal-like variant of MCF-7 breast cancer cells |
| Q28118356 | Endoplasmic reticulum-associated ubiquitin-conjugating enzyme Ube2j1 is a novel substrate of MK2 (MAPKAP kinase-2) involved in MK2-mediated TNFα production |
| Q89462234 | Engineering of a Polydisperse Small Heat-Shock Protein Reveals Conserved Motifs of Oligomer Plasticity |
| Q73148545 | Enhanced stability of alpha B-crystallin in the presence of small heat shock protein Hsp27 |
| Q90311388 | Epigenetic Alterations of Heat Shock Proteins (HSPs) in Cancer |
| Q28251704 | Essential role of the NH2-terminal WD/EPF motif in the phosphorylation-activated protective function of mammalian Hsp27 |
| Q46880176 | Estrogen signals to the preservation of endothelial cell form and function |
| Q34244942 | Evidence for an essential function of the N terminus of a small heat shock protein in vivo, independent of in vitro chaperone activity |
| Q28728855 | Evidence of prognostic relevant expression profiles of heat-shock proteins and glucose-regulated proteins in oesophageal adenocarcinomas |
| Q44416322 | Exercise‐induced HSP27, HSP70 and MAPK responses in human skeletal muscle |
| Q36831360 | Expression of phosphorylated heat shock protein 27 during corneal epithelial wound healing. |
| Q40684878 | Expression of the anti-apoptotic protein Hsp27 during both the keratinocyte differentiation and dedifferentiation of HaCat cells: expression linked to changes in intracellular protein organization? |
| Q47584707 | Extracellular small heat shock proteins: exosomal biogenesis and function |
| Q64964435 | Folding Status Is Determinant over Traffic-Competence in Defining CFTR Interactors in the Endoplasmic Reticulum. |
| Q92807672 | Functional and structural characterization of HspB1/Hsp27 from Chinese hamster ovary cells |
| Q43884429 | Functional regions of rice heat shock protein, Oshsp16.9, required for conferring thermotolerance in Escherichia coli |
| Q40623717 | Gene Expression Profiling in Ataxin-3 Expressing Cell Lines Reveals Distinct Effects of Normal and Mutant Ataxin-3 |
| Q46900372 | Glucose and diabetes: effects on podocyte and glomerular p38MAPK, heat shock protein 25, and actin cytoskeleton |
| Q28187877 | HSP22, a new member of the small heat shock protein superfamily, interacts with mimic of phosphorylated HSP27 ((3D)HSP27) |
| Q46418307 | HSP25 inhibits radiation-induced apoptosis through reduction of PKCdelta-mediated ROS production |
| Q40609416 | HSP25 is involved in two steps of the differentiation of PAM212 keratinocytes |
| Q36768592 | HSP27 Alleviates Cardiac Aging in Mice via a Mechanism Involving Antioxidation and Mitophagy Activation. |
| Q36128439 | HSP27 and cell death in spinocerebellar ataxia type 3. |
| Q37622321 | HSP27: mechanisms of cellular protection against neuronal injury |
| Q28554563 | HSPB1 Enhances SIRT2-Mediated G6PD Activation and Promotes Glioma Cell Proliferation |
| Q42358226 | HSPB1 facilitates ERK-mediated phosphorylation and degradation of BIM to attenuate endoplasmic reticulum stress-induced apoptosis. |
| Q38630044 | HSPB1 mutations causing hereditary neuropathy in humans disrupt non-cell autonomous protection of motor neurons |
| Q39655631 | HSPB7 is the most potent polyQ aggregation suppressor within the HSPB family of molecular chaperones |
| Q64245078 | Heat Shock Protein 27 Phosphorylation Regulates Tumor Cell Migration under Shear Stress |
| Q36010596 | Heat Shock Protein Beta-1 Modifies Anterior to Posterior Purkinje Cell Vulnerability in a Mouse Model of Niemann-Pick Type C Disease |
| Q33247162 | Heat shock protects cardiac cells from doxorubicin-induced toxicity by activating p38 MAPK and phosphorylation of small heat shock protein 27. |
| Q36298929 | Heat shock protein 27 (HSP27): biomarker of disease and therapeutic target |
| Q33713871 | Heat shock protein 27 as a new therapeutic target for radiation sensitization of head and neck squamous cell carcinoma |
| Q44005958 | Heat shock protein 27 delivered via a herpes simplex virus vector can protect neurons of the hippocampus against kainic-acid-induced cell loss |
| Q53579649 | Heat shock protein 27 functions in inflammatory gene expression and transforming growth factor-beta-activated kinase-1 (TAK1)-mediated signaling. |
| Q37337809 | Heat shock protein 27 is a potential indicator for response to YangZheng XiaoJi and chemotherapy agents in cancer cells. |
| Q43624329 | Heat shock protein 27 is a substrate of cGMP-dependent protein kinase in intact human platelets: phosphorylation-induced actin polymerization caused by HSP27 mutants |
| Q38987349 | Heat shock protein 27 is involved in PCV2 infection in PK-15 cells |
| Q45929966 | Heat shock protein 27 is involved in SUMO-2/3 modification of heat shock factor 1 and thereby modulates the transcription factor activity. |
| Q34292270 | Heat shock protein 27 phosphorylation state is associated with cancer progression |
| Q37548226 | Heat shock protein 27 phosphorylation: kinases, phosphatases, functions and pathology |
| Q36550110 | Heat shock protein 27: its potential role in vascular disease |
| Q35021738 | Heat shock protein B1-deficient mice display impaired wound healing |
| Q37490459 | Heat shock protein-27 protects human bronchial epithelial cells against oxidative stress-mediated apoptosis: possible implication in asthma. |
| Q35368150 | Heat shock protein: hard worker or bad offender for gastric diseases |
| Q28272905 | Heat shock proteins and heat shock factor 1 in carcinogenesis and tumor development: an update |
| Q38015052 | Heat shock proteins in hematopoietic malignancies. |
| Q34421860 | Heat shock proteins in the photobiology of human skin |
| Q35120739 | Heat shock proteins, cellular chaperones that modulate mitochondrial cell death pathways |
| Q37081794 | Heat shock proteins: essential proteins for apoptosis regulation |
| Q51841677 | Heat shock treatment prior to myocardial infarction results in reduced ventricular remodeling. |
| Q42228570 | Heat shock treatment protects against angiotensin II-induced hypertension and inflammation in aorta |
| Q47755897 | Heat shock treatment suppresses angiotensin II-induced activation of NF-kappaB pathway and heart inflammation: a role for IKK depletion by heat shock? |
| Q34282224 | Heat-shock proteins as regulators of apoptosis |
| Q35739969 | Heterooligomeric complexes of human small heat shock proteins |
| Q35800479 | High-mobility group box 1 is essential for mitochondrial quality control |
| Q61797396 | How a fortuitous collaboration helped catalyze new insights into helper proteins |
| Q35056214 | Hsp-27 induction requires POU4F2/Brn-3b TF in doxorubicin-treated breast cancer cells, whereas phosphorylation alters its cellular localisation following drug treatment |
| Q28590261 | Hsp105 but not Hsp70 family proteins suppress the aggregation of heat-denatured protein in the presence of ADP |
| Q36805868 | Hsp27 (HspB1) and alphaB-crystallin (HspB5) as therapeutic targets. |
| Q24536983 | Hsp27 as a negative regulator of cytochrome C release |
| Q34013226 | Hsp27 associates with the titin filament system in heat-shocked zebrafish cardiomyocytes |
| Q90776636 | Hsp27 chaperones FUS phase separation under the modulation of stress-induced phosphorylation |
| Q33917298 | Hsp27 negatively regulates cell death by interacting with cytochrome c. |
| Q45304513 | Hsp27 overexpression in the R6/2 mouse model of Huntington's disease: chronic neurodegeneration does not induce Hsp27 activation |
| Q37037631 | Hsp27 protects against ischemic brain injury via attenuation of a novel stress-response cascade upstream of mitochondrial cell death signaling |
| Q35129790 | Hsp27 protects mitochondria of thermotolerant cells against apoptotic stimuli |
| Q49034746 | Hsp27 upregulation and phosphorylation is required for injured sensory and motor neuron survival |
| Q44547066 | Hsp27, Hsp70, and metallothionein in MDCK and LLC-PK1 renal epithelial cells: effects of prolonged exposure to cadmium |
| Q37761860 | HspB1 (Hsp 27) expression and neuroprotection in the retina |
| Q47234323 | HspB1 and Hsc70 chaperones engage distinct tau species and have different inhibitory effects on amyloid formation |
| Q38671885 | HspB1, HspB5 and HspB4 in Human Cancers: Potent Oncogenic Role of Some of Their Client Proteins |
| Q34137356 | HspB2/myotonic dystrophy protein kinase binding protein (MKBP) as a novel molecular chaperone: structural and functional aspects |
| Q34778800 | Human-derived physiological heat shock protein 27 complex protects brain after focal cerebral ischemia in mice |
| Q47806822 | Hypoxia alters biophysical properties of endothelial cells via p38 MAPK- and Rho kinase-dependent pathways |
| Q35586798 | Identification of peptides in human Hsp20 and Hsp27 that possess molecular chaperone and anti-apoptotic activities |
| Q30390809 | Impaired Chaperone Activity of Human Heat Shock Protein Hsp27 Site-Specifically Modified with Argpyrimidine |
| Q43570147 | In vitro dephosphorylation of alpha-crystallin is dependent on the state of oligomerization |
| Q36814293 | In vitro evaluation of aspirin-induced HspB1 against heat stress damage in chicken myocardial cells |
| Q40260241 | In vivo resolution of oligomers with fluorescence photobleaching recovery histograms |
| Q48266629 | Induction of Hsp27 and Hsp32 stress proteins and vimentin in glial cells of the rat hippocampus following hyperthermia |
| Q24290301 | Inhibition of Daxx-mediated apoptosis by heat shock protein 27 |
| Q43948430 | Injury to retinal ganglion cells induces expression of the small heat shock protein Hsp27 in the rat visual system |
| Q57784964 | Integrated proteomics reveals apoptosis-related mechanisms associated with placental malaria |
| Q24299015 | Interaction of human HSP22 (HSPB8) with other small heat shock proteins |
| Q24338273 | Interactions of HSP22 (HSPB8) with HSP20, alphaB-crystallin, and HSPB3 |
| Q28191615 | Interferon-gamma downregulates Hsp27 expression and suppresses the negative regulation of cell death in oral squamous cell carcinoma lines |
| Q28571586 | Interleukin-11-induced heat shock protein 25 confers intestinal epithelial-specific cytoprotection from oxidant stress |
| Q83227932 | Interplay of disordered and ordered regions of a human small heat shock protein yields an ensemble of 'quasi-ordered' states |
| Q33235022 | Involvement of nuclear accumulation of heat shock protein 27 in leptomycin B-induced apoptosis in HeLa cells |
| Q39984360 | Kinase activity, heat shock protein 27 phosphorylation, and lung epithelial cell glutathione |
| Q39241021 | Lack of MK2 inhibits myofibroblast formation and exacerbates pulmonary fibrosis |
| Q37947562 | Large potentials of small heat shock proteins |
| Q91889110 | Ligand Binding Site Structure Shapes Folding, Assembly and Degradation of Homomeric Protein Complexes |
| Q92826350 | Limited Oxidative Stress Favors Resistance to Skeletal Muscle Atrophy in Hibernating Brown Bears (Ursus Arctos) |
| Q64058050 | Local unfolding of the HSP27 monomer regulates chaperone activity |
| Q39633520 | Locally synthesized HSP27 in hepatocytes: Is it possibly a novel strategy against human liver ischemia/reperfusion injury? |
| Q39952714 | Long-term exposure to low lithium concentrations stimulates proliferation, modifies stress protein expression pattern and enhances resistance to oxidative stress in SH-SY5Y cells |
| Q45140564 | Luminal bacterial flora determines physiological expression of intestinal epithelial cytoprotective heat shock proteins 25 and 72. |
| Q35237725 | MAPK-activated protein kinase 2-deficiency causes hyperacute tumor necrosis factor-induced inflammatory shock. |
| Q40224907 | MAPK-activated protein kinase-2 (MK2)-mediated formation and phosphorylation-regulated dissociation of the signal complex consisting of p38, MK2, Akt, and Hsp27. |
| Q36371939 | MAPKAP kinases - MKs - two's company, three's a crowd |
| Q64115759 | MAPKAPK2: the master regulator of RNA-binding proteins modulates transcript stability and tumor progression |
| Q42214286 | Mammalian Hsp22 is a heat-inducible small heat-shock protein with chaperone-like activity |
| Q38987805 | Mammalian HspB1 (Hsp27) is a molecular sensor linked to the physiology and environment of the cell. |
| Q74633092 | Mechanism of chaperone function in small heat shock proteins. Two-mode binding of the excited states of T4 lysozyme mutants by alphaA-crystallin |
| Q44279161 | Mechanism of chaperone function in small heat-shock proteins. Phosphorylation-induced activation of two-mode binding in alphaB-crystallin |
| Q38443894 | Medical implications of understanding the functions of human small heat shock proteins. |
| Q42497634 | Migratory marker expression in fibroblast foci of idiopathic pulmonary fibrosis |
| Q90929747 | Millimeter-wave pulsed heating in vitro: cell mortality and heat shock response |
| Q42546446 | Modification and reorganization of the cytoprotective cellular chaperone Hsp27 during herpes simplex virus type 1 infection |
| Q74333700 | Modulation of HSP25 expression during anterior horn motor neuron degeneration in the paralysé mouse mutant |
| Q41421660 | Modulation of HSP27 alters hypoxia-induced endothelial permeability and related signaling pathways |
| Q37167901 | Molecular chaperones and photoreceptor function. |
| Q54581403 | Monitoring protein-protein interactions in mammalian cells by trans-SUMOylation. |
| Q74251218 | Monodisperse Hsp16.3 nonamer exhibits dynamic dissociation and reassociation, with the nonamer dissociation prerequisite for chaperone-like activity |
| Q37022352 | Multi-kinase inhibitors can associate with heat shock proteins through their NH2-termini by which they suppress chaperone function |
| Q39588599 | Multiple protein kinases determine the phosphorylated state of the small heat shock protein, HSP27, in SH-SY5Y neuroblastoma cells |
| Q33205918 | Multiple-stress analysis for isolation of Drosophila longevity genes |
| Q44902269 | Mutants in a small heat shock protein that affect the oligomeric state. Analysis and allele-specific suppression |
| Q61409880 | Naloxone-precipitated morphine withdrawal evokes phosphorylation of heat shock protein 27 in rat heart through extracellular signal-regulated kinase |
| Q89860827 | Neuromuscular Diseases Due to Chaperone Mutations: A Review and Some New Results |
| Q40389152 | Neuroprotective effects of virally delivered HSPs in experimental stroke |
| Q42836657 | Neuroprotective preconditioning of rat brain cultures with ethanol: potential transduction by PKC isoforms and focal adhesion kinase upstream of increases in effector heat shock proteins |
| Q45115040 | Oligomeric Hsp33 with enhanced chaperone activity: gel filtration, cross-linking, and small angle x-ray scattering (SAXS) analysis |
| Q35969785 | Oral proteasome inhibitor with strong preclinical efficacy in myeloma models |
| Q46720773 | Overexpression of hsp27 Rescued Neuronal Cell Death and Reduction in Life- and Health-Span in Drosophila melanogaster Against Prolonged Exposure to Dichlorvos |
| Q37288545 | Pathology-dependent effects linked to small heat shock proteins expression: an update |
| Q36900533 | Pharmacoinformatic and molecular docking studies reveal potential novel antidepressants against neurodegenerative disorders by targeting HSPB8. |
| Q91559617 | Phosphoproteomic analysis sheds light on intracellular signaling cascades triggered by Formyl-Peptide Receptor 2 |
| Q36018192 | Phosphoproteomic profiling of tumor tissues identifies HSP27 Ser82 phosphorylation as a robust marker of early ischemia. |
| Q52650419 | Phosphorylated Hsp27 is mutually exclusive with ATRX loss and the IDH1R132H mutation and may predict better prognosis among glioblastomas without the IDH1 mutation and ATRX loss. |
| Q30352338 | Phosphorylation and concomitant structural changes in human 2-Cys peroxiredoxin isotype I differentially regulate its peroxidase and molecular chaperone functions. |
| Q37254023 | Phosphorylation dependence of hsp27 multimeric size and molecular chaperone function |
| Q54593816 | Phosphorylation of human small heat shock protein HspB8 (Hsp22) by ERK1 protein kinase. |
| Q51767452 | Phosphorylation status of heat shock protein 27 influences neurite growth in adult dorsal root ganglion sensory neurons in vitro. |
| Q44442854 | Phosphorylation-dependent structural alterations in the small hsp30 chaperone are associated with cellular recovery. |
| Q31629257 | Phosphorylation-induced change of the oligomerization state of alpha B-crystallin |
| Q38899532 | Pnck overexpression in HER-2 gene-amplified breast cancer causes Trastuzumab resistance through a paradoxical PTEN-mediated process |
| Q33677951 | Power of proteomics in linking oxidative stress and female infertility |
| Q38119789 | Premature lung aging and cellular senescence in the pathogenesis of idiopathic pulmonary fibrosis and COPD/emphysema |
| Q53677561 | Prevention of kidney ischemia/reperfusion-induced functional injury, MAPK and MAPK kinase activation, and inflammation by remote transient ureteral obstruction. |
| Q37526773 | Pro-inflammatory cytokines downregulate Hsp27 and cause apoptosis of human retinal capillary endothelial cells |
| Q73107565 | Probing the roles of the only universally conserved leucine residue (Leu122) in the oligomerization and chaperone-like activity of Mycobacterium tuberculosis small heat shock protein Hsp16.3. |
| Q33624625 | Protective effect of phosphorylated Hsp27 in coronary arteries through actin stabilization |
| Q42267219 | Protective effect of post-ischaemic viral delivery of heat shock proteins in vivo |
| Q35684873 | Protein alterations in women with chronic widespread pain--An explorative proteomic study of the trapezius muscle. |
| Q28346924 | Protein kinase inhibitors can suppress stress-induced dissociation of Hsp27 |
| Q34551875 | Proteomic analysis of skeletal muscle in insulin-resistant mice: response to 6-week aerobic exercise |
| Q43986444 | Proteomic analysis of skin irritation reveals the induction of HSP27 by sodium lauryl sulphate in human skin |
| Q33536101 | Proteomic analysis reveals virus-specific Hsp25 modulation in cardiac myocytes |
| Q34252034 | Purinergic receptor antagonists inhibit odorant-induced heat shock protein 25 induction in mouse olfactory epithelium |
| Q50983540 | Quantitative Phospho-proteomic Analysis of TNFα/NFκB Signaling Reveals a Role for RIPK1 Phosphorylation in Suppressing Necrotic Cell Death. |
| Q40690597 | Quercetin, apoptosis, heat shock |
| Q43079029 | Recombinant heat shock protein 27 (HSP27/HSPB1) protects against cadmium-induced oxidative stress and toxicity in human cervical cancer cells. |
| Q28576331 | Recruitment of phosphorylated small heat shock protein Hsp27 to nuclear speckles without stress |
| Q34706977 | Regulation of TAK1/TAB1-mediated IL-1β signaling by cytoplasmic PPARβ/δ. |
| Q46847339 | Regulation of contractility by Hsp27 and Hic-5 in rat mesenteric small arteries |
| Q39453587 | Regulation of cyclooxygenase 2 mRNA stability by the mitogen-activated protein kinase p38 signaling cascade |
| Q37450141 | Regulation of endothelial barrier function by TGF-β type I receptor ALK5: potential role of contractile mechanisms and heat shock protein 90. |
| Q34085642 | Regulation of vimentin intermediate filaments in endothelial cells by hypoxia |
| Q55021241 | Review on PACAP-Induced Transcriptomic and Proteomic Changes in Neuronal Development and Repair. |
| Q36244261 | Rho-kinase regulates prostaglandin D(2)-stimulated heat shock protein 27 induction in osteoblasts |
| Q46616117 | Role of F-actin organization in p38 MAP kinase-mediated apoptosis and necrosis in neonatal rat cardiomyocytes subjected to simulated ischemia and reoxygenation |
| Q44732930 | Role of heat shock protein 27 in cytoskeletal remodeling of the airway smooth muscle cell |
| Q35764321 | Role of heat shock proteins during polyglutamine neurodegeneration: mechanisms and hypothesis |
| Q44639137 | Roles for αB-crystallin and HSPB2 in protecting the myocardium from ischemia-reperfusion-induced damage in a KO mouse model |
| Q46971344 | Roles of MAPKAPK-2 and HSP27 in the reduction of renal ischemia-reperfusion injury by ischemic postconditioning in rats |
| Q43199663 | Rosiglitazone prevents the progression of renal injury in DOCA-salt hypertensive rats |
| Q43941680 | S-thiolation of HSP27 regulates its multimeric aggregate size independently of phosphorylation |
| Q38373448 | SUMOylation of HSP27 by small ubiquitin-like modifier 2/3 promotes proliferation and invasion of hepatocellular carcinoma cells |
| Q35801033 | Sequence, structure, and dynamic determinants of Hsp27 (HspB1) equilibrium dissociation are encoded by the N-terminal domain |
| Q42463699 | Sequential induction of Hsp25 and proliferating cell nuclear antigen in the kidney after burn |
| Q35139418 | Sequestration of toxic oligomers by HspB1 as a cytoprotective mechanism |
| Q34333585 | Serine 59 phosphorylation of {alpha}B-crystallin down-regulates its anti-apoptotic function by binding and sequestering Bcl-2 in breast cancer cells. |
| Q33233579 | Short-chain fatty acid mediated phosphorylation of heat shock protein 25: effects on camptothecin-induced apoptosis. |
| Q36081156 | Site-directed mutagenesis substituting cysteine for serine in 2-Cys peroxiredoxin (2-Cys Prx A) of Arabidopsis thaliana effectively improves its peroxidase and chaperone functions |
| Q28215719 | Size matters: of the small HSP27 and its large oligomers |
| Q36276295 | Small heat shock proteins in inherited peripheral neuropathies |
| Q58585311 | Small heat shock proteins: Simplicity meets complexity |
| Q33840764 | Small heat-shock proteins and their potential role in human disease |
| Q38263437 | Small heat-shock proteins: important players in regulating cellular proteostasis |
| Q43237439 | Small interfering RNA-mediated silencing of heat shock protein 27 (HSP27) Increases chemosensitivity to paclitaxel by increasing production of reactive oxygen species in human ovarian cancer cells (HO8910). |
| Q37577461 | Small molecule sensitization to TRAIL is mediated via nuclear localization, phosphorylation and inhibition of chaperone activity of Hsp27. |
| Q28116822 | Some properties of human small heat shock protein Hsp20 (HspB6) |
| Q24312122 | Some properties of human small heat shock protein Hsp22 (H11 or HspB8) |
| Q36108921 | Specific hepatic delivery of procollagen α1(I) small interfering RNA in lipid-like nanoparticles resolves liver fibrosis |
| Q40691314 | Stress-mediated signaling in PC12 cells - the role of the small heat shock protein, Hsp27, and Akt in protecting cells from heat stress and nerve growth factor withdrawal |
| Q28204103 | Structure and function of the small heat shock protein/alpha-crystallin family of molecular chaperones |
| Q37424170 | Structure and mechanism of protein stability sensors: chaperone activity of small heat shock proteins |
| Q44214861 | Structure and properties of avian small heat shock protein with molecular weight 25 kDa. |
| Q28346488 | Substitution of conserved methionines by leucines in chloroplast small heat shock protein results in loss of redox-response but retained chaperone-like activity |
| Q35574405 | Surface expression of Hsp25 and Hsp72 differentially regulates tumor growth and metastasis |
| Q37373120 | Synthesis and anticancer mechanism investigation of dual Hsp27 and tubulin inhibitors |
| Q34415685 | TRAIL-induced caspase/p38 activation is responsible for the increased catalytic and invasive activities of Akt |
| Q41660505 | Targeting Heat Shock Proteins in Cancer: A Promising Therapeutic Approach |
| Q47383368 | Targeting Hsp27/eIF4E interaction with phenazine compound: a promising alternative for castration-resistant prostate cancer treatment. |
| Q36849634 | Targeting Mitogen-Activated Protein Kinase-Activated Protein Kinase 2 (MAPKAPK2, MK2): Medicinal Chemistry Efforts To Lead Small Molecule Inhibitors to Clinical Trials |
| Q88888157 | Targeting of PP2Cδ By a Small Molecule C23 Inhibits High Glucose-Induced Breast Cancer Progression In Vivo |
| Q37199137 | The 27-kDa heat shock protein confers cytoprotective effects through a beta 2-adrenergic receptor agonist-initiated complex with beta-arrestin |
| Q97519821 | The Global Phosphorylation Landscape of SARS-CoV-2 Infection |
| Q44476890 | The R1 subunit of herpes simplex virus ribonucleotide reductase has chaperone-like activity similar to Hsp27. |
| Q90419495 | The Role of the Arginine in the Conserved N-Terminal Domain RLFDQxFG Motif of Human Small Heat Shock Proteins HspB1, HspB4, HspB5, HspB6, and HspB8 |
| Q43600511 | The chaperone-like activity of a small heat shock protein is lost after sulfoxidation of conserved methionines in a surface-exposed amphipathic alpha-helix |
| Q33593911 | The endoplasmic reticulum chaperone Cosmc directly promotes in vitro folding of T-synthase |
| Q39212393 | The growing world of small heat shock proteins: from structure to functions |
| Q37308806 | The level of Hsp27 in lymphocytes is negatively associated with a higher risk of lung cancer |
| Q43140307 | The microtubule-associated protein, NUD-1, exhibits chaperone activity in vitro |
| Q30489583 | The role of Hsp27 and actin in the regulation of movement in human cancer cells responding to heat shock |
| Q37223453 | The role of stress proteins in prostate cancer |
| Q43131932 | The role of the cysteine residue in the chaperone and anti-apoptotic functions of human Hsp27. |
| Q47347524 | The role of αB-crystallin in skeletal and cardiac muscle tissues |
| Q40868364 | The small heat shock protein Hsp22 of Drosophila melanogaster is a mitochondrial protein displaying oligomeric organization |
| Q90180972 | Thermal Bioprinting Causes Ample Alterations of Expression of LUCAT1, IL6, CCL26, and NRN1L Genes and Massive Phosphorylation of Critical Oncogenic Drug Resistance Pathways in Breast Cancer Cells |
| Q37220099 | Thermal unfolding and aggregation of actin |
| Q44614714 | Thyroxine pretreatment increases basal myocardial heat-shock protein 27 expression and accelerates translocation and phosphorylation of this protein upon ischaemia |
| Q92881932 | Titanium Dioxide Nanoparticles Alter the Cellular Phosphoproteome in A549 Cells |
| Q44605228 | Translational Thermotolerance Provided by Small Heat Shock Proteins Is Limited to Cap-dependent Initiation and Inhibited by 2-Aminopurine |
| Q36476527 | Tubular expression of heat-shock protein 27 inhibits fibrogenesis in obstructive nephropathy |
| Q57244970 | Upregulation of HSP27 in a Transgenic Model of ALS |
| Q28543000 | Viral activation of MK2-hsp27-p115RhoGEF-RhoA signaling axis causes cytoskeletal rearrangements, p-body disruption and ARE-mRNA stabilization |
| Q28592083 | alpha-Crystallin distribution in retinal pigment epithelium and effect of gene knockouts on sensitivity to oxidative stress |
| Q53687330 | eIF4E Phosphorylation in Prostate Cancer. |
| Q51157275 | microRNA-577 suppresses tumor growth and enhances chemosensitivity in colorectal cancer. |
| Q40462718 | p38 MAPK/HSP25 signaling mediates cadmium-induced contraction of mesangial cells and renal glomeruli. |
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