Viral vectors for gene transfer: a review of their use in the treatment of human diseases

scientific article (publication date: August 2000)

Viral vectors for gene transfer: a review of their use in the treatment of human diseases is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P6179Dimensions Publication ID1007837576
P356DOI10.2165/00003495-200060020-00002
P3181OpenCitations bibliographic resource ID2091671
P698PubMed publication ID10983732
P5875ResearchGate publication ID12338027

P2093author name stringW Walther
U Stein
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Adenovirus-mediated gene transfer transiently corrects the chloride transport defect in nasal epithelia of patients with cystic fibrosis.Q42483788
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Interaction of vesicular stomatitis virus-G pseudotyped retrovirus with CD34+ and CD34+ CD38- hematopoietic progenitor cellsQ44102494
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Mapping of herpes simplex virus-1 neurovirulence to gamma 134.5, a gene nonessential for growth in cultureQ44460699
Recombinant adenovirus gene transfer in adults with partial ornithine transcarbamylase deficiency (OTCD).Q44544229
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Modification of tumor suppressor gene expression and induction of apoptosis in non-small cell lung cancer (NSCLC) with an adenovirus vector expressing wildtype p53 and cisplatinQ44803404
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Generation of a transgenic model for retrovirus-mediated gene therapy for hepatocellular carcinoma is thwarted by the lack of transgene expressionQ44939592
Herpesvirus vector gene transfer and expression of beta-glucuronidase in the central nervous system of MPS VII miceQ45175987
Correction of hemophilia B in canine and murine models using recombinant adeno-associated viral vectorsQ45299117
Adeno-associated virus-mediated delivery of erythropoietin leads to sustained elevation of hematocrit in nonhuman primatesQ45753061
Recombinant adeno-associated virus for muscle directed gene therapyQ45764433
Development of a replication-deficient recombinant vaccinia virus vaccine effective against parainfluenza virus 3 infection in an animal modelQ45765329
A recombinant vaccinia virus encoding human papillomavirus types 16 and 18, E6 and E7 proteins as immunotherapy for cervical cancer.Q45769906
Long-term survival of rats harboring brain neoplasms treated with ganciclovir and a herpes simplex virus vector that retains an intact thymidine kinase gene.Q45782481
First EBV vaccine trial in humans using recombinant vaccinia virus expressing the major membrane antigenQ45785005
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Pseudotyped retroviral vectors for studies of human gene therapyQ40429875
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Results of a phase I trial of a recombinant vaccinia virus that expresses carcinoembryonic antigen in patients with advanced colorectal cancerQ40928916
Transient immunosuppression by FK506 permits a sustained high-level dystrophin expression after adenovirus-mediated dystrophin minigene transfer to skeletal muscles of adult dystrophic (mdx) mice.Q40931797
Recombinant adeno-associated virus (rAAV) vectors for somatic gene therapy: recent advances and potential clinical applicationsQ40936864
Behavioral recovery in 6-hydroxydopamine-lesioned rats by cotransduction of striatum with tyrosine hydroxylase and aromatic L-amino acid decarboxylase genes using two separate adeno-associated virus vectorsQ40988268
High-titer adeno-associated viral vectors from a Rep/Cap cell line and hybrid shuttle virusQ40992577
Inducible expression of p21WAF-1/CIP-1/SDI-1 from a promoter conversion retroviral vectorQ41071646
Cell type specific and inducible promoters for vectors in gene therapy as an approach for cell targetingQ41139949
Recombinant adenovirus deleted of all viral genes for gene therapy of cystic fibrosisQ41226051
Targeting retrovirus entryQ41239958
FK506 immunosuppression to control the immune reactions triggered by first-generation adenovirus-mediated gene transferQ41275978
Retroviral targeted deliveryQ41295238
Correlation between complementation group for immortality and the cellular distribution of mortalin.Q41391947
Multiply attenuated lentiviral vector achieves efficient gene delivery in vivoQ29616612
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Chimeric viral vectors--the best of both worlds?Q33544037
Packaging cells based on inducible gene amplification for the production of adeno-associated virus vectorsQ33783728
Improved gene expression upon transfer of the adenosine deaminase minigene outside the transcriptional unit of a retroviral vectorQ33856071
Ligand-directed retroviral targeting of human breast cancer cellsQ33868131
Stable gene transfer and tissue-specific expression of a human globin gene using adenoviral vectors.Q33880416
Receptor co-operation in retrovirus entry: recruitment of an auxiliary entry mechanism after retargeted bindingQ33886233
In vitro and in vivo synthesis of the hepatitis B virus surface antigen and of the receptor for polymerized human serum albumin from recombinant human adenovirusesQ33932227
Characterization of a preferred site on human chromosome 19q for integration of adeno-associated virus DNA by non-homologous recombinationQ33938668
Generation of targeted retroviral vectors by using single-chain variable fragment: an approach to in vivo gene deliveryQ34066344
Generation of a high-titer retroviral vector capable of expressing high levels of the human beta-globin geneQ34073641
Attenuated multi–mutated herpes simplex virus–1 for the treatment of malignant gliomasQ34297434
A versatile and potentially general approach to the targeting of specific cell types by retroviruses: application to the infection of human cells by means of major histocompatibility complex class I and class II antigens by mouse ecotropic murine leQ34321338
Correction of lysosomal storage in the liver and spleen of MPS VII mice by implantation of genetically modified skin fibroblastsQ34352418
Gene transfer into humans--immunotherapy of patients with advanced melanoma, using tumor-infiltrating lymphocytes modified by retroviral gene transductionQ34354588
An adenovirus mutant that replicates selectively in p53-deficient human tumor cellsQ34399844
Applications of pox virus vectors to vaccination: an updateQ34403246
The ADA human gene therapy clinical protocol: Points to Consider response with clinical protocol, July 6, 1990.Q34408549
Human gene therapyQ34419327
Transcriptional Silencing of Retroviral Vectors.Q34450066
Adeno-associated virus vectors can be efficiently produced without helper virusQ34479933
Comparison of promoter suppression in avian and murine retrovirus vectorsQ35058620
Retroviral vectors containing putative internal ribosome entry sites: development of a polycistronic gene transfer system and applications to human gene therapyQ35064037
Self-inactivating retroviral vectors designed for transfer of whole genes into mammalian cellsQ35604467
A general method for the generation of high-titer, pantropic retroviral vectors: highly efficient infection of primary hepatocytesQ35796872
Multiple modifications in cis elements of the long terminal repeat of retroviral vectors lead to increased expression and decreased DNA methylation in embryonic carcinoma cells.Q35831286
Retroviral retargeting by envelopes expressing an N-terminal binding domain.Q35848344
High-titer packaging cells producing recombinant retroviruses resistant to human serumQ35851698
Adenovirus type 5 and 7 capsid chimera: fiber replacement alters receptor tropism without affecting primary immune neutralization epitopesQ35858284
Targeted infection of human cells via major histocompatibility complex class I molecules by Moloney murine leukemia virus-derived viruses displaying single-chain antibody fragment-envelope fusion proteins.Q35860180
A viral vaccine vector that expresses foreign genes in lymph nodes and protects against mucosal challenge.Q35861566
cis-acting elements that mediate the negative regulation of Moloney murine leukemia virus in mouse early embryosQ35866586
A phase 1-2 clinical trial of gene therapy for recurrent glioblastoma multiforme by tumor transduction with the herpes simplex thymidine kinase gene followed by ganciclovir. GLI328 European-Canadian Study GroupQ45862712
Arterial gene therapy for therapeutic angiogenesis in patients with peripheral artery diseaseQ45866523
A controlled study of adenoviral-vector-mediated gene transfer in the nasal epithelium of patients with cystic fibrosisQ45866575
T lymphocyte-directed gene therapy for ADA- SCID: initial trial results after 4 years.Q45866838
Adenovirus-mediated gene transfer for cystic fibrosis: quantitative evaluation of repeated in vivo vector administration to the lungQ45867192
Clearance of adenovirus-infected hepatocytes by MHC class I-restricted CD4+ CTLs in vivoQ45868140
Construction and characterization of retroviral vectors expressing biologically active human interleukin-12.Q45868776
Stage I clinical trial of gene therapy for hemophilia B.Q45872616
Cytokine mobilization of peripheral blood stem cells in patients with Gaucher disease with a view to gene therapy.Q45875786
The efficiency of cell targeting by recombinant retroviruses depends on the nature of the receptor and the composition of the artificial cell-virus linkerQ45876126
Prolonged metabolic correction in adult ornithine transcarbamylase-deficient mice with adenoviral vectorsQ45876696
Gene transfer into the mouse retina mediated by an adeno-associated viral vectorQ45877692
Direct gene transfer to the liver with herpes simplex virus type 1 vectors: transient production of physiologically relevant levels of circulating factor IXQ45879558
Retroviral display of antibody fragments; interdomain spacing strongly influences vector infectivity.Q45879817
Episomal expression of wild-type CFTR corrects cAMP-dependent chloride transport in respiratory epithelial cellsQ45881865
Functional correction of Fanconi anemia group A hematopoietic cells by retroviral gene transferQ45883938
Use of EBV-based Vector/HVJ-liposome complex vector for targeted gene therapy of EBV-associated neoplasmsQ45884636
A latent, nonpathogenic HSV-1-derived vector stably expresses beta-galactosidase in mouse neuronsQ46135759
ONYX-015, an E1B gene-attenuated adenovirus, causes tumor-specific cytolysis and antitumoral efficacy that can be augmented by standard chemotherapeutic agentsQ46343726
Adeno-associated viral vector-mediated gene transfer of human blood coagulation factor IX into mouse liverQ48004746
A novel multiply-mutated HSV-1 strain for the treatment of human brain tumorsQ48762505
Cell-surface receptor for ecotropic murine retroviruses is a basic amino-acid transporter.Q50798159
ONYX-015: clinical data are encouragingQ56898602
Retrovirus-Mediated Transfer of the cDNA for Human Glucocerebrosidase into Peripheral Blood Repopulating Cells of Patients with Gaucher's Disease. University of Wisconsin, Madison, WisconsinQ60160336
Human papillomavirus-specific cytotoxic T lymphocytes in patients with cervical intraepithelial neoplasia grade IIIQ64382267
Aerosol administration of a recombinant adenovirus expressing CFTR to cystic fibrosis patients: a phase I clinical trialQ64382613
Adenoviruses: group name proposed for new respiratory-tract virusesQ64386110
Phase I study of cytokine-gene modified autologous neuroblastoma cells for treatment of relapsed/refractory neuroblastomaQ67987475
Autologous bone marrow transplant for children with AML in first complete remission: use of marker genes to investigate the biology of marrow reconstitution and the mechanism of relapseQ68000944
Immunization of cancer patients using autologous cancer cells modified by insertion of the gene for tumor necrosis factorQ68094544
A phase I trial of high-dose carboplatin and etoposide with autologous marrow support for treatment of stage D neuroblastoma in first remission: use of marker genes to investigate the biology of marrow reconstitution and the mechanism of relapseQ68266879
Autologous bone marrow transplantation for CML in which retroviral markers are used to discriminate between relapse which arises from systemic disease remaining after preparative therapy versus relapse due to residual leukemia cells in autologous maQ68274666
A gene delivery system activatable by disease-associated matrix metalloproteinasesQ73254121
A phase I/II study of tgAAV-CF for the treatment of chronic sinusitis in patients with cystic fibrosisQ74530902
Efficient and persistent gene transfer of AAV-CFTR in maxillary sinusQ77292224
Prolonged gene expression and cell survival after infection by a herpes simplex virus mutant defective in the immediate-early genes encoding ICP4, ICP27, and ICP22.Q35868577
Role of viral antigens in destructive cellular immune responses to adenovirus vector-transduced cells in mouse lungs.Q35871002
Toward highly efficient cell-type-specific gene transfer with retroviral vectors displaying single-chain antibodies.Q35875806
Humoral, mucosal, and cellular immunity in response to a human immunodeficiency virus type 1 immunogen expressed by a Venezuelan equine encephalitis virus vaccine vector.Q35881081
Highly efficient and sustained gene transfer in adult neurons with a lentivirus vector.Q35891440
Stability without a centromereQ36185004
Adeno-associated virus 2-mediated high efficiency gene transfer into immature and mature subsets of hematopoietic progenitor cells in human umbilical cord bloodQ36363237
Sustained correction of bleeding disorder in hemophilia B mice by gene therapyQ36454880
Vesicular stomatitis virus G glycoprotein pseudotyped retroviral vectors: concentration to very high titer and efficient gene transfer into mammalian and nonmammalian cellsQ36506251
Modifications in the binding domain of avian retrovirus envelope protein to redirect the host range of retroviral vectorsQ36622965
Characterization of a bicistronic retroviral vector composed of the swine vesicular disease virus internal ribosome entry siteQ36686421
Gene transfer by retrovirus vectors occurs only in cells that are actively replicating at the time of infectionQ36720691
Human artificial episomal chromosomes for cloning large DNA fragments in human cellsQ36729587
Sustained secretion of human alpha-1-antitrypsin from murine muscle transduced with adeno-associated virus vectorsQ36734619
Transient dominant selection of recombinant vaccinia viruses.Q36808769
A safe packaging line for gene transfer: separating viral genes on two different plasmidsQ36865708
Development of retrovirus vectors useful for expressing genes in cultured murine embryonal cells and hematopoietic cells in vivoQ36873087
Neonatal gene transfer leads to widespread correction of pathology in a murine model of lysosomal storage disease.Q37181003
T lymphocytes with a normal ADA gene accumulate after transplantation of transduced autologous umbilical cord blood CD34+ cells in ADA-deficient SCID neonates.Q37182935
A deletion mutant in the human cytomegalovirus gene encoding IE1(491aa) is replication defective due to a failure in autoregulationQ37248409
Genetically engineered poxviruses for recombinant gene expression, vaccination, and safetyQ37249251
Negative-strand RNA viruses: genetic engineering and applicationsQ37249720
Use of virion DNA as a cloning vector for the construction of mutant and recombinant herpesvirusesQ37251335
Efficient infection of a human T-cell line and of human primary peripheral blood leukocytes with a pseudotyped retrovirus vectorQ37271693
Efficient transfer and sustained high expression of the human glucocerebrosidase gene in mice and their functional macrophages following transplantation of bone marrow transduced by a retroviral vectorQ37319132
A new adenoviral vector: Replacement of all viral coding sequences with 28 kb of DNA independently expressing both full-length dystrophin and beta-galactosidaseQ37551841
Expression of chimeric envelope proteins in helper cell lines and integration into Moloney murine leukemia virus particles.Q38359595
Replication of plasmids derived from bovine papilloma virus type 1 and Epstein-Barr virus in cells in cultureQ39160064
Minimal requirement for a lentivirus vector based on human immunodeficiency virus type 1.Q39577503
Receptor-binding domain of murine leukemia virus envelope glycoproteins.Q39868615
Long-term gene delivery into the livers of immunocompetent mice with E1/E4-defective adenovirusesQ39879953
Type C retrovirus inactivation by human complement is determined by both the viral genome and the producer cell.Q40042967
Packaging system for rapid production of murine leukemia virus vectors with variable tropismQ40067097
Construction of retroviral vectors for targeted delivery and expression of therapeutic genesQ40368888
A transient three-plasmid expression system for the production of high titer retroviral vectorsQ40393091
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectvector-borne diseaseQ2083837
P304page(s)249-71
P577publication date2000-08-01
P1433published inDrugsQ3040094
P1476titleViral vectors for gene transfer: a review of their use in the treatment of human diseases
P478volume60