Linking the Rb and polycomb pathways

scientific article (publication date: September 2001)

Linking the Rb and polycomb pathways is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/S1097-2765(01)00346-X
P698PubMed publication ID11583618

P50authorSusana GonzaloQ57416940
P2093author name stringS Wong
D C Dean
M Gavin
A Dahiya
P2860cites workCyclin E associates with BAF155 and BRG1, components of the mammalian SWI-SNF complex, and alters the ability of BRG1 to induce growth arrestQ22008677
RING1 is associated with the polycomb group protein complex and acts as a transcriptional repressorQ24312810
Interference with the expression of a novel human polycomb protein, hPc2, results in cellular transformation and apoptosisQ24315842
A human homologue of Saccharomyces cerevisiae SNF2/SWI2 and Drosophila brm genes potentiates transcriptional activation by the glucocorticoid receptorQ24317715
The retinoblastoma protein and BRG1 form a complex and cooperate to induce cell cycle arrestQ24321861
Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4aQ24324559
C-Terminal binding protein is a transcriptional repressor that interacts with a specific class of vertebrate Polycomb proteinsQ24554534
RING1 interacts with multiple Polycomb-group proteins and displays tumorigenic activityQ24554805
Cyclin A expression is under negative transcriptional control during the cell cycleQ24648922
ZEB represses transcription through interaction with the corepressor CtBPQ24653823
A mechanism for Rb/p130-mediated transcription repression involving recruitment of the CtBP corepressorQ24656541
The retinoblastoma protein and cell cycle controlQ27860722
Functions of mammalian Polycomb group and trithorax group related genesQ41600966
Retinoblastoma protein switches the E2F site from positive to negative elementQ41613404
Mechanism of active transcriptional repression by the retinoblastoma proteinQ42479902
p16INK4a, but not constitutively active pRb, can impose a sustained G1 arrest: molecular mechanisms and implications for oncogenesis.Q45861136
Xenopus embryonic E2F is required for the formation of ventral and posterior cell fates during early embryogenesisQ47847474
The cyclin-dependent protein kinases and the control of cell division.Q51130096
Murine Polycomb- and trithorax-group genes regulate homeotic pathways and beyond.Q52194910
Cyclin/Cdk-Dependent Initiation of DNA Replication in a Human Cell-Free SystemQ58198972
Exit from G1 and S phase of the cell cycle is regulated by repressor complexes containing HDAC-Rb-hSWI/SNF and Rb-hSWI/SNFQ73707174
Active transcriptional repression by the Rb-E2F complex mediates G1 arrest triggered by p16INK4a, TGFbeta, and contact inhibitionQ77310904
CDK inhibitors: positive and negative regulators of G1-phase progressionQ27860983
E2F4 and E2F5 play an essential role in pocket protein-mediated G1 controlQ28141003
Cdk phosphorylation triggers sequential intramolecular interactions that progressively block Rb functions as cells move through G1Q28145116
Ras signalling is required for inactivation of the tumour suppressor pRb cell-cycle control proteinQ28256250
Retinoblastoma protein represses transcription by recruiting a histone deacetylaseQ28262155
Rb interacts with histone deacetylase to repress transcriptionQ28263985
Ras signalling linked to the cell-cycle machinery by the retinoblastoma proteinQ28305440
Posterior transformation, neurological abnormalities, and severe hematopoietic defects in mice with a targeted deletion of the bmi-1 proto-oncogeneQ28505536
A Brg1 null mutation in the mouse reveals functional differences among mammalian SWI/SNF complexesQ28589309
RB-dependent S-phase response to DNA damageQ28609381
A gene complex controlling segmentation in DrosophilaQ29547506
Inhibitors of mammalian G1 cyclin-dependent kinasesQ29547907
E2F: a link between the Rb tumor suppressor protein and viral oncoproteinsQ29618375
The oncogene and Polycomb-group gene bmi-1 regulates cell proliferation and senescence through the ink4a locusQ29619815
The E2F transcription factor is a cellular target for the RB proteinQ29620422
Regulation of the cyclin E gene by transcription factor E2F1Q33651067
Induction of p21(WAF1/CIP1) and inhibition of Cdk2 mediated by the tumor suppressor p16(INK4a)Q33958412
Target gene specificity of E2F and pocket protein family members in living cellsQ33964977
Role of the LXCXE binding site in Rb functionQ33965546
The Rb/E2F pathway: expanding roles and emerging paradigmsQ34052659
Polycombing the genome: PcG, trxG, and chromatin silencingQ34066536
BRG-1 is required for RB-mediated cell cycle arrestQ34509523
Multiple docking sites on substrate proteins form a modular system that mediates recognition by ERK MAP kinaseQ35186927
Inhibition of DNA synthesis by RB: effects on G1/S transition and S-phase progressionQ35206804
Functional antagonism of the Polycomb-Group genes eed and Bmi1 in hemopoietic cell proliferationQ35208075
Functional interactions between the hBRM/hBRG1 transcriptional activators and the pRB family of proteinsQ36558284
Domains A and B in the Rb pocket interact to form a transcriptional repressor motifQ36562117
The Rb family contains a conserved cyclin-dependent-kinase-regulated transcriptional repressor motifQ36564503
RB and hbrm cooperate to repress the activation functions of E2F1Q36591354
Induced expression of p16(INK4a) inhibits both CDK4- and CDK2-associated kinase activity by reassortment of cyclin-CDK-inhibitor complexesQ39444837
E2F is required to prevent inappropriate S-phase entry of mammalian cellsQ39450236
Requirement of cyclin E-Cdk2 inhibition in p16(INK4a)-mediated growth suppressionQ39575910
The cell cycle and the retinoblastoma protein familyQ40733277
Restoration of retinoblastoma mediated signaling to Cdk2 results in cell cycle arrestQ40885726
Accumulation of cyclin B1 requires E2F and cyclin-A-dependent rearrangement of the anaphase-promoting complexQ40919505
The p21(Cip1) and p27(Kip1) CDK 'inhibitors' are essential activators of cyclin D-dependent kinases in murine fibroblastsQ40967344
lin-35 and lin-53, two genes that antagonize a C. elegans Ras pathway, encode proteins similar to Rb and its binding protein RbAp48.Q40983720
Myc and Ras collaborate in inducing accumulation of active cyclin E/Cdk2 and E2F.Q41109594
The Polycomb and trithorax group proteins of Drosophila: trans-regulators of homeotic gene functionQ41126293
Reversal of terminal differentiation and control of DNA replication: cyclin A and Cdk2 specifically localize at subnuclear sites of DNA replicationQ41526613
P433issue3
P407language of work or nameEnglishQ1860
P304page(s)557-569
P577publication date2001-09-01
P1433published inMolecular CellQ3319468
P1476titleLinking the Rb and polycomb pathways
P478volume8