Vasodilating effect of norethisterone and its 5 alpha metabolites: a novel nongenomic action

scientific article (publication date: 15 August 2003)

Vasodilating effect of norethisterone and its 5 alpha metabolites: a novel nongenomic action is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/S0014-2999(03)02106-X
P698PubMed publication ID12954372

P2093author name stringCarlos M Villalón
Mercedes Perusquía
Gregorio Pérez-Palacios
Ana E Lemus
Erika Navarrete
Gustavo A García
P2860cites workRisks and benefits of estrogen plus progestin in healthy postmenopausal women: principal results From the Women's Health Initiative randomized controlled trialQ27860743
5alpha-reduction of norethisterone enhances its binding affinity for androgen receptors but diminishes its androgenic potencyQ28240617
Stereospecificity of the intracellular binding of norethisterone and its A-ring reduced metabolitesQ28306011
The progestin levonorgestrel induces endothelium-independent relaxation of rabbit jugular vein via inhibition of calcium entry and protein kinase C: role of cyclic AMPQ28344628
Randomized trial of estrogen plus progestin for secondary prevention of coronary heart disease in postmenopausal women. Heart and Estrogen/progestin Replacement Study (HERS) Research GroupQ29615228
Estrogen-induced cardiorenal protection: potential cellular, biochemical, and molecular mechanismsQ31955778
Effect of medroxyprogesterone acetate and norethisterone on serum-stimulated and estradiol-inhibited proliferation of human coronary artery smooth muscle cellsQ32000800
Progestins and cardiovascular risk markersQ34100036
Hormone therapy to prevent disease and prolong life in postmenopausal womenQ34262585
Nongenomic action of steroids in myometrial contractilityQ34381521
Metabolism of levonorgestrel, norethindrone, and structurally related contraceptive steroidsQ37857707
17 beta-Estradiol attenuates voltage-dependent Ca2+ currents in A7r5 vascular smooth muscle cell lineQ41475091
Noncardiovascular disease outcomes during 6.8 years of hormone therapy: Heart and Estrogen/progestin Replacement Study follow-up (HERS II).Q42679385
Influence of 5alpha- and 5beta-reduced progestins on the contractility of isolated human myometrium at termQ43644408
Testosterone-induced relaxation of rat aorta is androgen structure specific and involves K+ channel activationQ43805283
The vasodepressor effect of androgens in pithed rats: potential role of calcium channelsQ44222354
Properties of a progesterone-induced relaxation in human placental arteries and veinsQ45085183
Evidence that a non-aromatizable metabolite of norethisterone induces estrogen-dependent pituitary progestin receptorsQ48380966
Progesterone induces endothelium-independent relaxation of rabbit coronary artery in vitroQ50795554
Insulin resistance, secretion, and elimination in postmenopausal women receiving oral or transdermal hormone replacement therapy.Q52394286
Possible role of Ca2+ channels in the vasodilating effect of 5beta-dihydrotestosterone in rat aorta.Q54093590
Steroids. LIV.1Synthesis of 19-Nov-17α-ethynyltestosterone and 19-Nor-17α-methyltestosterone2Q55953222
Identification and measurement by gas chromatography-mass spectrometry of norethindrone and metabolites in human urine and bloodQ67564498
Differential effects of transdermal estradiol and sequential progestogens on impedance to flow within the uterine arteries of postmenopausal womenQ67576081
Hormone replacement therapy and cardiovascular diseaseQ67592974
Role of endothelium in the vasodilating effect of progestins and androgens on the rat thoracic aortaQ71351387
Transdermal estrogen replacement therapy: beneficial effects on hemostatic risk factors for cardiovascular diseaseQ71505808
Norethisterone metabolites modulate the uteroglobin and progesterone receptor gene expression in prepubertal rabbitsQ72143605
Effects of hormone replacement therapy on reactivity of atherosclerotic coronary arteries in cynomolgus monkeysQ72811876
Variations of progesterone receptor and c-fos gene expression in the rat uterus after treatment with norethisterone and its A-ring reduced metabolitesQ73012759
Estrogens, progestins and coronary artery reactivityQ73122348
Medroxyprogesterone interferes with ovarian steroid protection against coronary vasospasmQ73122425
Temporal changes in clinic and ambulatory blood pressure during cyclic post-menopausal hormone replacement therapyQ73138313
Nomegestrol acetate and vascular reactivity: nonhuman primate experimentsQ73276073
Vascular Effects of Progesterone : Role of Cellular Calcium RegulationQ73513442
Hemodynamic effects of transdermal estradiol alone and combined with norethisterone acetateQ73584187
Mechanisms of relaxation of rat aorta in response to progesterone and synthetic progestinsQ74379872
The long-term effects of oral and transdermal postmenopausal hormone replacement therapy on nitric oxide, endothelin-1, prostacyclin, and thromboxaneQ74561287
Hormone replacement therapyQ77088378
Antagonistic effects of 17 beta-estradiol, progesterone, and testosterone on Ca2+ entry mechanisms of coronary vasoconstrictionQ77297673
Coadministration of nomegestrol acetate does not diminish the beneficial effects of estradiol on coronary artery dilator responses in nonhuman primates (Macaca fascicularis)Q77580502
P433issue1-3
P407language of work or nameEnglishQ1860
P304page(s)161-9
P577publication date2003-08-15
P1433published inEuropean Journal of PharmacologyQ1376712
P1476titleVasodilating effect of norethisterone and its 5 alpha metabolites: a novel nongenomic action
P478volume475

Reverse relations

Q37608577Hormone therapy and cardiovascular risk markers and disease: focus on progestagenscites workP2860

Search more.