| scholarly article | Q13442814 |
| P50 | author | Jun Ninomiya-Tsuji | Q64516241 |
| Richard Gaynor | Q111083810 | ||
| P2093 | author name string | Kunihiro Matsumoto | |
| Giichi Takaesu | |||
| Rama M Surabhi | |||
| Kyu-Jin Park | |||
| P2860 | cites work | Identification of a cell protein (FIP-3) as a modulator of NF-kappaB activity and as a target of an adenovirus inhibitor of tumor necrosis factor alpha-induced apoptosis | Q22008750 |
| The kinase TAK1 can activate the NIK-I kappaB as well as the MAP kinase cascade in the IL-1 signalling pathway | Q22009096 | ||
| Analysis of domains in the IKKalpha and IKKbeta proteins that regulate their kinase activity | Q22253426 | ||
| TAK1 is a ubiquitin-dependent kinase of MKK and IKK | Q24291454 | ||
| RNA interference--2001. | Q34174586 | ||
| The IKKbeta subunit of IkappaB kinase (IKK) is essential for nuclear factor kappaB activation and prevention of apoptosis | Q36368249 | ||
| Embryonic lethality, liver degeneration, and impaired NF-kappa B activation in IKK-beta-deficient mice | Q40956523 | ||
| Severe liver degeneration in mice lacking the IkappaB kinase 2 gene | Q40962152 | ||
| Abnormal morphogenesis but intact IKK activation in mice lacking the IKKalpha subunit of IkappaB kinase | Q41644582 | ||
| IkappaB kinase alpha is essential for mature B cell development and function | Q42175977 | ||
| Limb and skin abnormalities in mice lacking IKKalpha | Q42470314 | ||
| The Conserved Pre-mRNA Splicing Factor U2AF from Drosophila : Requirement for Viability | Q46013977 | ||
| IKKgamma /NEMO facilitates the recruitment of the IkappaB proteins into the IkappaB kinase complex | Q74258243 | ||
| Expanding small RNA interference | Q78021693 | ||
| TAK1 mediates the ceramide signaling to stress-activated protein kinase/c-Jun N-terminal kinase | Q24310066 | ||
| TAB1: an activator of the TAK1 MAPKKK in TGF-beta signal transduction | Q24312956 | ||
| The NF-kappa B and I kappa B proteins: new discoveries and insights | Q24313579 | ||
| IKK-gamma is an essential regulatory subunit of the IkappaB kinase complex | Q24316469 | ||
| IKK-1 and IKK-2: cytokine-activated IkappaB kinases essential for NF-kappaB activation | Q24321727 | ||
| A cytokine-responsive IkappaB kinase that activates the transcription factor NF-kappaB | Q24321775 | ||
| IkappaB kinase-beta: NF-kappaB activation and complex formation with IkappaB kinase-alpha and NIK | Q24321797 | ||
| IkappaB kinase (IKK)-associated protein 1, a common component of the heterogeneous IKK complex | Q24530641 | ||
| Receptor activator of NF-kappaB ligand (RANKL) activates TAK1 mitogen-activated protein kinase kinase kinase through a signaling complex containing RANK, TAB2, and TRAF6 | Q24537518 | ||
| The alpha and beta subunits of IkappaB kinase (IKK) mediate TRAF2-dependent IKK recruitment to tumor necrosis factor (TNF) receptor 1 in response to TNF | Q24550953 | ||
| Interleukin-1 (IL-1) receptor-associated kinase leads to activation of TAK1 by inducing TAB2 translocation in the IL-1 signaling pathway | Q24550984 | ||
| Domains in the SPT5 protein that modulate its transcriptional regulatory properties | Q24554258 | ||
| IKK1-deficient mice exhibit abnormal development of skin and skeleton | Q24604269 | ||
| RNA interference is mediated by 21- and 22-nucleotide RNAs | Q27860764 | ||
| Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans | Q27860867 | ||
| Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells | Q27860926 | ||
| NF-kappa B and Rel proteins: evolutionarily conserved mediators of immune responses | Q27861101 | ||
| TAB2, a novel adaptor protein, mediates activation of TAK1 MAPKKK by linking TAK1 to TRAF6 in the IL-1 signal transduction pathway | Q28140039 | ||
| Functional interactions of transforming growth factor beta-activated kinase 1 with IkappaB kinases to stimulate NF-kappaB activation | Q28140522 | ||
| Activation of the IkappaB kinase complex by TRAF6 requires a dimeric ubiquitin-conjugating enzyme complex and a unique polyubiquitin chain | Q28142613 | ||
| Identification and characterization of an IkappaB kinase | Q28245341 | ||
| The IkappaB kinase complex (IKK) contains two kinase subunits, IKKalpha and IKKbeta, necessary for IkappaB phosphorylation and NF-kappaB activation | Q28252726 | ||
| Identification of a member of the MAPKKK family as a potential mediator of TGF-beta signal transduction | Q28271470 | ||
| Missing pieces in the NF-kappaB puzzle | Q29547864 | ||
| Activators and target genes of Rel/NF-kappaB transcription factors | Q29547882 | ||
| Complementation cloning of NEMO, a component of the IkappaB kinase complex essential for NF-kappaB activation | Q29617419 | ||
| NF-kappa B: ten years after | Q29618566 | ||
| Bridging the gap: composition, regulation, and physiological function of the IkappaB kinase complex | Q33663188 | ||
| How NF-kappaB is activated: the role of the IkappaB kinase (IKK) complex | Q33797139 | ||
| Double-stranded RNA as a template for gene silencing | Q33905186 | ||
| Specific inhibition of gene expression by small double-stranded RNAs in invertebrate and vertebrate systems | Q33933613 | ||
| P433 | issue | 1 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | NF-κB | Q411114 |
| P304 | page(s) | 105-15 | |
| P577 | publication date | 2003-02-07 | |
| P1433 | published in | Journal of Molecular Biology | Q925779 |
| P1476 | title | TAK1 is critical for IkappaB kinase-mediated activation of the NF-kappaB pathway | |
| P478 | volume | 326 |
| Q34436147 | 1'-Acetoxychavicol acetate inhibits growth of human oral carcinoma xenograft in mice and potentiates cisplatin effect via proinflammatory microenvironment alterations |
| Q42793623 | A cytosolic ATM/NEMO/RIP1 complex recruits TAK1 to mediate the NF-kappaB and p38 mitogen-activated protein kinase (MAPK)/MAPK-activated protein 2 responses to DNA damage |
| Q36477515 | A longitudinal genome-wide association study of anti-tumor necrosis factor response among Japanese patients with rheumatoid arthritis |
| Q45931428 | A mechanism for the suppression of interleukin-1-induced nuclear factor kappaB activation by protein phosphatase 2Ceta-2. |
| Q34552027 | A novel pentamethoxyflavone down-regulates tumor cell survival and proliferative and angiogenic gene products through inhibition of IκB kinase activation and sensitizes tumor cells to apoptosis by cytokines and chemotherapeutic agents. |
| Q36089051 | A pervasive role of ubiquitin conjugation in activation and termination of IkappaB kinase pathways |
| Q54542919 | A20 and ABIN-3 possibly promote regression of trehalose 6,6'-dimycolate (TDM)-induced granuloma by interacting with an NF-kappa B signaling protein, TAK-1. |
| Q91813324 | ANKRD44 Gene Silencing: A Putative Role in Trastuzumab Resistance in Her2-Like Breast Cancer |
| Q35149590 | Activated macrophage survival is coordinated by TAK1 binding proteins |
| Q38344824 | Activation of intrinsic and extrinsic proapoptotic signaling pathways in interleukin-18-mediated human cardiac endothelial cell death |
| Q37036746 | Advances in targeting IKK and IKK-related kinases for cancer therapy |
| Q37041538 | Altered TAB1:I kappaB kinase interaction promotes transforming growth factor beta-mediated nuclear factor-kappaB activation during breast cancer progression |
| Q28208531 | Amyloid β peptide (Aβ42) activates PLC-δ1 promoter through the NF-κB binding site |
| Q33862077 | Arsenic trioxide-dependent activation of thousand-and-one amino acid kinase 2 and transforming growth factor-beta-activated kinase 1. |
| Q28117206 | Autoactivation of transforming growth factor beta-activated kinase 1 is a sequential bimolecular process |
| Q36166598 | BMP signaling and stem cell regulation |
| Q92549917 | Below the surface: The inner lives of TLR4 and TLR9 |
| Q54337036 | Calcineurin subunit B upregulates β-interferon production by phosphorylation of interferon regulatory factor 3 via Toll-like receptor 4. |
| Q50963973 | Cardioprotective Role of Tumor Necrosis Factor Receptor-Associated Factor 2 by Suppressing Apoptosis and Necroptosis. |
| Q39139714 | Carrageenan-induced colonic inflammation is reduced in Bcl10 null mice and increased in IL-10-deficient mice |
| Q34079481 | Chronic inflammation and cancer: potential chemoprevention through nuclear factor kappa B and p53 mutual antagonism |
| Q34767624 | Cooperative control of Drosophila immune responses by the JNK and NF-kappaB signaling pathways |
| Q38900181 | Coordinate loss of MAP3K7 and CHD1 promotes aggressive prostate cancer |
| Q39929790 | Coronarin D, a labdane diterpene, inhibits both constitutive and inducible nuclear factor-kappa B pathway activation, leading to potentiation of apoptosis, inhibition of invasion, and suppression of osteoclastogenesis |
| Q45182335 | Critical roles of threonine 187 phosphorylation in cellular stress-induced rapid and transient activation of transforming growth factor-beta-activated kinase 1 (TAK1) in a signaling complex containing TAK1-binding protein TAB1 and TAB2. |
| Q28577795 | Cross-talk of the related bioactivity mediators in serum after injection of soluble TNF-α receptor on silicosis model of rats |
| Q35347850 | Crosstalk of reactive oxygen species and NF-κB signaling |
| Q45083578 | DUBbing down innate immunity |
| Q37814068 | Deubiquitinases in the regulation of NF-κB signaling |
| Q46844281 | Differential regulation of c-Jun N-terminal kinase and NF-kappaB pathway by caffeic acid phenethyl ester in astroglial and monocytic cells |
| Q36165374 | Dissecting role of regulatory factors in NF-kappaB pathway with siRNA. |
| Q36584442 | Effects of (5Z)-7-oxozeaenol on MDA-MB-231 breast cancer cells. |
| Q36584470 | Effects of (5Z)-7-oxozeaenol on the oxidative pathway of cancer cells. |
| Q37683123 | Efficient replication by herpes simplex virus type 1 involves activation of the IkappaB kinase-IkappaB-p65 pathway |
| Q34551310 | Elucidation of the c-Jun N-terminal kinase pathway mediated by Estein-Barr virus-encoded latent membrane protein 1. |
| Q35807430 | Epithelial transforming growth factor β-activated kinase 1 (TAK1) is activated through two independent mechanisms and regulates reactive oxygen species |
| Q35946356 | Erlotinib protects against LPS-induced endotoxicity because TLR4 needs EGFR to signal |
| Q50335551 | Essential function for the kinase TAK1 in innate and adaptive immune responses |
| Q24337661 | Essential role for TAX1BP1 in the termination of TNF-alpha-, IL-1- and LPS-mediated NF-kappaB and JNK signaling |
| Q90638896 | Evidence for the Involvement of the Master Transcription Factor NF-κB in Cancer Initiation and Progression |
| Q34483207 | Expanding role of cyclin dependent kinases in cytokine inducible gene expression. |
| Q36561723 | Exploiting our knowledge of NF-kappaB signaling for the treatment of mammary cancer |
| Q39818388 | Expression of tak1 and tram induces synergistic pro-inflammatory signalling and adjuvants DNA vaccines |
| Q59807770 | Extracorporeal shockwave against inflammation mediated by GPR120 receptor in cyclophosphamide-induced rat cystitis model |
| Q38504848 | FAF1 suppresses IkappaB kinase (IKK) activation by disrupting the IKK complex assembly |
| Q35815962 | Functions of NF-kappaB1 and NF-kappaB2 in immune cell biology |
| Q24630455 | GPR120 is an omega-3 fatty acid receptor mediating potent anti-inflammatory and insulin-sensitizing effects |
| Q37087280 | Generation of a conditional mutant allele for Tab1 in mouse |
| Q33342232 | Genetic analysis of host resistance: Toll-like receptor signaling and immunity at large |
| Q36580099 | Genetic analysis of innate immunity |
| Q59335681 | Genetic and pharmacological validation of TAK1 inhibition in macrophages as a therapeutic strategy to effectively inhibit TNF secretion |
| Q40124526 | Glutamine regulates the human epithelial intestinal HCT-8 cell proteome under apoptotic conditions |
| Q56501517 | Gomisin N enhances TNF-α-induced apoptosis via inhibition of the NF-κB and EGFR survival pathways |
| Q35839884 | Gossypin, a pentahydroxy glucosyl flavone, inhibits the transforming growth factor beta-activated kinase-1-mediated NF-kappaB activation pathway, leading to potentiation of apoptosis, suppression of invasion, and abrogation of osteoclastogenesis. |
| Q30840705 | Greensporones: resorcylic acid lactones from an aquatic Halenospora sp. |
| Q80393092 | HIF-1 and NF-kappaB-mediated upregulation of CXCR1 and CXCR2 expression promotes cell survival in hypoxic prostate cancer cells |
| Q33756614 | HIV-1 Vpr stimulates NF-κB and AP-1 signaling by activating TAK1. |
| Q53579649 | Heat shock protein 27 functions in inflammatory gene expression and transforming growth factor-beta-activated kinase-1 (TAK1)-mediated signaling. |
| Q43164932 | Helicobacter pylori induces IkappaB kinase alpha nuclear translocation and chemokine production in gastric epithelial cells |
| Q35784954 | Herpesvirus saimiri STP-A oncoprotein utilizes Src family protein tyrosine kinase and tumor necrosis factor receptor-associated factors to elicit cellular signal transduction |
| Q36617084 | Homeostatic interactions between MEKK3 and TAK1 involved in NF-kappaB signaling |
| Q35874956 | IAPs limit activation of RIP kinases by TNF receptor 1 during development |
| Q40331218 | IKK alpha regulates estrogen-induced cell cycle progression by modulating E2F1 expression |
| Q33276239 | IKK/NF-κB signaling contributes to glioblastoma stem cell maintenance |
| Q34117399 | Identification and functional characterization of novel phosphorylation sites in TAK1-binding protein (TAB) 1. |
| Q28267530 | IkappaB kinase alpha regulates subcellular distribution and turnover of cyclin D1 by phosphorylation |
| Q36637874 | IkappaB kinase complexes: gateways to NF-kappaB activation and transcription |
| Q44757920 | Immune Activation of NF-κB and JNK Requires Drosophila TAK1 |
| Q34787151 | In TNF-stimulated cells, RIPK1 promotes cell survival by stabilizing TRAF2 and cIAP1, which limits induction of non-canonical NF-kappaB and activation of caspase-8 |
| Q34625534 | In vivo knockdown of TAK1 accelerates bone marrow proliferation/differentiation and induces systemic inflammation |
| Q40265640 | Indirubin enhances tumor necrosis factor-induced apoptosis through modulation of nuclear factor-kappa B signaling pathway. |
| Q34490968 | Inducible HSP70 antagonizes IL-1β cytocidal effects through inhibiting NF-kB activation via destabilizing TAK1 in HeLa cells |
| Q33619331 | Inflammatory mediator TAK1 regulates hair follicle morphogenesis and anagen induction shown by using keratinocyte-specific TAK1-deficient mice |
| Q24297091 | Inhibition of autophagy by TAB2 and TAB3 |
| Q35804937 | Inhibitor of apoptosis proteins as intracellular signaling intermediates |
| Q79394740 | Investigation of interleukin 1beta-mediated regulation of NF-kappaB activation in colonic cells reveals divergence between PKB and PDK-transduced events |
| Q35048889 | Involvement of reactive oxygen species in cyclic stretch-induced NF-kappaB activation in human fibroblast cells |
| Q35971438 | K63-linked ubiquitination in kinase activation and cancer |
| Q34420804 | MCP-induced protein 1 deubiquitinates TRAF proteins and negatively regulates JNK and NF-kappaB signaling |
| Q34407038 | MUC1 oncoprotein activates the IkappaB kinase beta complex and constitutive NF-kappaB signalling |
| Q35931767 | MUC1-C activates the TAK1 inflammatory pathway in colon cancer |
| Q50335885 | Mass spectrometric analysis of the endogenous type I interleukin-1 (IL-1) receptor signaling complex formed after IL-1 binding identifies IL-1RAcP, MyD88, and IRAK-4 as the stable components |
| Q79322514 | Mechanisms of proinflammatory cytokine-induced biphasic NF-kappaB activation |
| Q36487056 | MicroRNAs and toll-like receptor/interleukin-1 receptor signaling |
| Q37338875 | Morin (3,5,7,2',4'-Pentahydroxyflavone) abolishes nuclear factor-kappaB activation induced by various carcinogens and inflammatory stimuli, leading to suppression of nuclear factor-kappaB-regulated gene expression and up-regulation of apoptosis |
| Q28117317 | Mutations in MAP3K7 that Alter the Activity of the TAK1 Signaling Complex Cause Frontometaphyseal Dysplasia |
| Q35207092 | Mutual regulation between deubiquitinase CYLD and retroviral oncoprotein Tax |
| Q28584007 | NEMO oligomerization in the dynamic assembly of the IkappaB kinase core complex |
| Q28271031 | NF-kappaB and the immune response |
| Q36925725 | NF-kappaB and the intestine: friend or foe? |
| Q35196538 | NF-kappaB in pancreatic cancer |
| Q26822516 | NF-κB, the first quarter-century: remarkable progress and outstanding questions |
| Q36306990 | Nemo-like kinase (NLK) negatively regulates NF-kappa B activity through disrupting the interaction of TAK1 with IKKβ. |
| Q50055560 | Nemopilema nomurai jellyfish venom exerts an anti-metastatic effect by inhibiting Smad- and NF-κB-mediated epithelial-mesenchymal transition in HepG2 cells |
| Q39013667 | Non-Smad Signaling Pathways of the TGF-β Family |
| Q58246924 | Nordihydroguaiaretic acid suppresses the lipopolysaccharide-induced activation of macrophage through the down-regulation of TAK1 |
| Q40186974 | Novel insights into the cellular mechanisms of the anti-inflammatory effects of NF-kappaB essential modulator binding domain peptides |
| Q39549560 | Nuclear factor-κB2/p100 promotes endometrial carcinoma cell survival under hypoxia in a HIF-1α independent manner. |
| Q27000272 | Omega-3 Fatty Acids and FFAR4 |
| Q41485924 | Orange-spotted grouper Epinephelus coioides Tak1: molecular identification, expression analysis and functional study |
| Q24676236 | Osmotic stress activates the TAK1-JNK pathway while blocking TAK1-mediated NF-kappaB activation: TAO2 regulates TAK1 pathways |
| Q28593804 | Osteoclast differentiation is impaired in the absence of inhibitor of kappa B kinase alpha |
| Q34926779 | Osteopetrosis in TAK1-deficient mice owing to defective NF-κB and NOTCH signaling |
| Q24646391 | PKC beta regulates BCR-mediated IKK activation by facilitating the interaction between TAK1 and CARMA1 |
| Q36884257 | Pellino proteins: novel players in TLR and IL-1R signalling |
| Q41894880 | Phosphorylation of Thr-178 and Thr-184 in the TAK1 T-loop is required for interleukin (IL)-1-mediated optimal NFkappaB and AP-1 activation as well as IL-6 gene expression. |
| Q34310237 | Phosphorylation of p65(RelA) on Ser(547) by ATM represses NF-κB-dependent transcription of specific genes after genotoxic stress |
| Q54633678 | Pim-1 Regulates RANKL-Induced Osteoclastogenesis via NF-κB Activation and NFATc1 Induction |
| Q35084995 | Polyubiquitination events mediate polymethylmethacrylate (PMMA) particle activation of NF-kappaB pathway |
| Q38861590 | Post-translational control of NF-κB signaling by ubiquitination |
| Q28213409 | Protein phosphatase 2Cbeta association with the IkappaB kinase complex is involved in regulating NF-kappaB activity |
| Q33267561 | RNAi screen in mouse astrocytes identifies phosphatases that regulate NF-kappaB signaling |
| Q92581853 | Rap1 regulates hepatic stellate cell migration through the modulation of RhoA activity in response to TGF‑β1 |
| Q37774919 | Reactive oxygen species in TNFalpha-induced signaling and cell death. |
| Q38711461 | Receptor signaling in immune cell development and function |
| Q41179164 | Reduced infiltration and increased apoptosis of leukocytes at sites of inflammation by systemic administration of a membrane-permeable IkappaBalpha repressor |
| Q39627012 | Regulation of IκB Kinase by GβL through Recruitment of the Protein Phosphatases |
| Q37435968 | Regulation of JNK and p38 MAPK in the immune system: signal integration, propagation and termination. |
| Q24650223 | Regulation of cell proliferation and migration by TAK1 via transcriptional control of von Hippel-Lindau tumor suppressor |
| Q42136496 | Regulation of the JNK pathway by TGF-beta activated kinase 1 in rheumatoid arthritis synoviocytes |
| Q24559752 | Restoration of NF-kappaB activation by tumor necrosis factor alpha receptor complex-targeted MEKK3 in receptor-interacting protein-deficient cells |
| Q39473622 | Rhesus monkey TRIM5α represses HIV-1 LTR promoter activity by negatively regulating TAK1/TAB1/TAB2/TAB3-complex-mediated NF-κB activation |
| Q47871261 | Role for TAK1 in cigarette smoke-induced proinflammatory signaling and IL-8 release by human airway smooth muscle cells |
| Q36429389 | Role of IkappaB kinase in tumorigenesis |
| Q35177662 | Role of Jun and Jun kinase in resistance of cancer cells to therapy |
| Q33758352 | Role of MLK3 in the regulation of mitogen-activated protein kinase signaling cascades |
| Q36819381 | Role of mitogen-activated protein kinase kinase kinases in signal integration |
| Q37392558 | Role of p38 MAP Kinase Signal Transduction in Solid Tumors |
| Q24633992 | Role of the TAB2-related protein TAB3 in IL-1 and TNF signaling |
| Q44532400 | Roles for homotypic interactions and transautophosphorylation in IkappaB kinase beta IKKbeta) activation [corrected]. |
| Q91725373 | SIRT7 Regulates Lipopolysaccharide-Induced Inflammatory Injury by Suppressing the NF-κB Signaling Pathway |
| Q35555456 | Silica exposure is associated with increased risk of developing rheumatoid arthritis: results from the Swedish EIRA study |
| Q40433595 | Simultaneous blockade of NFkappaB, JNK, and p38 MAPK by a kinase-inactive mutant of the protein kinase TAK1 sensitizes cells to apoptosis and affects a distinct spectrum of tumor necrosis factor [corrected] target genes |
| Q33302050 | Single TNFalpha trimers mediating NF-kappaB activation: stochastic robustness of NF-kappaB signaling. |
| Q43171015 | Smad3-deficient chondrocytes have enhanced BMP signaling and accelerated differentiation |
| Q91943837 | Specificity, versatility, and control of TGF-β family signaling |
| Q39602471 | Stercurensin inhibits nuclear factor-κB-dependent inflammatory signals through attenuation of TAK1-TAB1 complex formation |
| Q28507577 | Subdomain VIII is a specificity-determining region in MEKK1 |
| Q36846045 | Suppression of Tak1 promotes prostate tumorigenesis |
| Q24530663 | TAB3, a new binding partner of the protein kinase TAK1 |
| Q36275375 | TAK1 Regulates Myocardial Response to Pathological Stress via NFAT, NFκB, and Bnip3 Pathways |
| Q50062411 | TAK1 inhibition ameliorates survival from graft-versus-host disease in an allogeneic murine marrow transplantation model |
| Q36528456 | TAK1 is a central mediator of NOD2 signaling in epidermal cells |
| Q40323227 | TAK1 is a component of the Epstein-Barr virus LMP1 complex and is essential for activation of JNK but not of NF-kappaB. |
| Q24676202 | TAK1 is a master regulator of epidermal homeostasis involving skin inflammation and apoptosis |
| Q43599859 | TAK1 is required for dermal wound healing and homeostasis |
| Q37484230 | TAK1 kinase determines TRAIL sensitivity by modulating reactive oxygen species and cIAP. |
| Q38180064 | TAK1 regulates hepatic cell survival and carcinogenesis |
| Q42124023 | TAK1 regulates reactive oxygen species and cell death in keratinocytes, which is essential for skin integrity |
| Q28504462 | TAK1, but not TAB1 or TAB2, plays an essential role in multiple signaling pathways in vivo |
| Q36981023 | TAK1-binding protein 1, TAB1, mediates osmotic stress-induced TAK1 activation but is dispensable for TAK1-mediated cytokine signaling |
| Q43004507 | TAK1-binding protein 2 facilitates ubiquitination of TRAF6 and assembly of TRAF6 with IKK in the IL-1 signaling pathway |
| Q46808873 | TAK1-mediated transcriptional activation of CD28-responsive element and AP-1-binding site within the IL-2 promoter in Jurkat T cells |
| Q34533855 | TLR and TNF-R1 activation of the MKK3/MKK6-p38α axis in macrophages is mediated by TPL-2 kinase |
| Q24541430 | TNFalpha- and IKKbeta-mediated TANK/I-TRAF phosphorylation: implications for interaction with NEMO/IKKgamma and NF-kappaB activation |
| Q50792035 | TRAF3 forms heterotrimers with TRAF2 and modulates its ability to mediate NF-{kappa}B activation. |
| Q34540475 | The API2-MALT1 fusion exploits TNFR pathway-associated RIP1 ubiquitination to promote oncogenic NF-κB signaling |
| Q40352645 | The C-terminal activating region 2 of the Epstein-Barr virus-encoded latent membrane protein 1 activates NF-kappaB through TRAF6 and TAK1. |
| Q36634002 | The CARMA1 signalosome links the signalling machinery of adaptive and innate immunity in lymphocytes |
| Q35621375 | The IKK NF-kappa B system: a treasure trove for drug development |
| Q37731922 | The TNF family member 4-1BBL sustains inflammation by interacting with TLR signaling components during late-phase activation |
| Q24338639 | The TRAF6 ubiquitin ligase and TAK1 kinase mediate IKK activation by BCL10 and MALT1 in T lymphocytes |
| Q24297208 | The Yersinia enterocolitica effector YopP inhibits host cell signalling by inactivating the protein kinase TAK1 in the IL-1 signalling pathway |
| Q36526359 | The dual-specificity phosphatase DUSP14 negatively regulates tumor necrosis factor- and interleukin-1-induced nuclear factor-κB activation by dephosphorylating the protein kinase TAK1 |
| Q54595193 | The kinase TAK1 integrates antigen and cytokine receptor signaling for T cell development, survival and function. |
| Q27027904 | The role of omega-3 fatty acid receptor GPR120 in insulin resistance |
| Q36105771 | The transcription factor NF-kappaB as drug target |
| Q24570126 | Toll-like receptor signalling |
| Q44309031 | Transforming growth factor (TGF)-beta-activated kinase 1 mimics and mediates TGF-beta-induced stimulation of type II collagen synthesis in chondrocytes independent of Col2a1 transcription and Smad3 signaling |
| Q30433440 | Transforming growth factor beta-activated kinase 1 (TAK1) kinase adaptor, TAK1-binding protein 2, plays dual roles in TAK1 signaling by recruiting both an activator and an inhibitor of TAK1 kinase in tumor necrosis factor signaling pathway |
| Q28244416 | Transforming growth factor-beta-activated kinase 1 is essential for differentiation and the prevention of apoptosis in epidermis |
| Q24306909 | Tumor necrosis factor-alpha-induced IKK phosphorylation of NF-kappaB p65 on serine 536 is mediated through the TRAF2, TRAF5, and TAK1 signaling pathway |
| Q36321691 | Ubiquitin protein modification and signal transduction: implications for inflammatory bowel diseases |
| Q29616322 | Ubiquitin signalling in the NF-kappaB pathway |
| Q36399446 | Ubiquitin, TAK1 and IKK: is there a connection? |
| Q39838992 | WDR34 is a novel TAK1-associated suppressor of the IL-1R/TLR3/TLR4-induced NF-kappaB activation pathway |
| Q27302812 | Withaferin A disrupts ubiquitin-based NEMO reorganization induced by canonical NF-κB signaling |
| Q24624946 | Wnt-1 signal induces phosphorylation and degradation of c-Myb protein via TAK1, HIPK2, and NLK |
| Q64262257 | miR-135 regulated breast cancer proliferation and epithelial-mesenchymal transition acts by the Wnt/β-catenin signaling pathway |
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