S 17092: a prolyl endopeptidase inhibitor as a potential therapeutic drug for memory impairment. Preclinical and clinical studies

scientific article (publication date: 2002)

S 17092: a prolyl endopeptidase inhibitor as a potential therapeutic drug for memory impairment. Preclinical and clinical studies is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

External links are
P356DOI10.1111/J.1527-3458.2002.TB00214.X
P3181OpenCitations bibliographic resource ID2909182
P932PMC publication ID6741683
P698PubMed publication ID12070525
P5875ResearchGate publication ID11303304

P2093author name stringPierre Lestage
David Guez
Guillaume De Nanteuil
Roeline Jochemsen
Pierre-Alain Boyer
Philippe Morain
Jean-Loïc Robin
P2860cites workS 17092-1, a highly potent, specific and cell permeant inhibitor of human proline endopeptidase.Q33859153
Fronto-striatal cognitive deficits at different stages of Parkinson's diseaseQ34296796
Visuospatial memory deficits at different stages of Parkinson's diseaseQ34354414
Behavioral characterization of quinolinate-induced lesions of the medial striatum: relevance for Huntington's diseaseQ34374332
Pharmacodynamic and pharmacokinetic profile of S 17092, a new orally active prolyl endopeptidase inhibitor, in elderly healthy volunteers. A phase I studyQ36055312
Neuropeptides and Alzheimer's diseaseQ37948072
Axonal regeneration, growth factors and neuropeptidesQ38179476
Evidence for a decrease in substance P content of substantia nigra in Huntington's choreaQ39130542
Prolyl endopeptidaseQ40164039
The role of neuropeptides in learning: focus on the neurokinin substance P.Q40400806
Recovery from unilateral 6-hydroxydopamine lesion of substantia nigra promoted by the neurotachykinin substance P 1-11.Q41092780
'Frontal' cognitive function in patients with Parkinson's disease 'on' and 'off' levodopaQ41437567
Effect of neuropeptides on cognitive function.Q41604656
Central injection of substance P elicits grooming behavior and motor inhibition in miceQ41702058
TRH attenuates scopolamine-induced memory impairment in humansQ41897125
Effect of thyrotropin releasing hormone (TRH) on acetylcholine release from different brain areas investigated by microdialysisQ42084295
New prolyl endopeptidase inhibitors: in vitro and in vivo activities of azabicyclo[2.2.2]octane, azabicyclo[2.2.1]heptane, and perhydroindole derivativesQ42555567
Substance P-like immunoreactivity is reduced in Alzheimer's disease cerebral cortexQ43480542
L-dopa withdrawal in Parkinson's disease selectively impairs cognitive performance in tests sensitive to frontal lobe dysfunctionQ43643543
Effects of the prolyl endopeptidase inhibitor S 17092 on cognitive deficits in chronic low dose MPTP-treated monkeysQ43854204
Behavioural effects of selective tachykinin agonists in midbrain dopamine regionsQ44316951
Substance P-like immunoreactive neurons are depleted in Alzheimer's disease cerebral cortexQ44800050
Essential role of neocortical acetylcholine in spatial memoryQ46181651
Knowing which and knowing what: a potential mouse model for age-related human declarative memory declineQ48098564
Delayed matching-to-sample, object retrieval, and discrimination reversal deficits in chronic low dose MPTP-treated monkeysQ48250417
A triple dissociation of memory systems: hippocampus, amygdala, and dorsal striatumQ48336730
Involvement of nicotinergic mechanisms in thyrotropin-releasing hormone-induced neurologic recovery after concussive head injury in the mouseQ48362552
Different effects of dopaminergic and anticholinergic therapies on cognitive and motor function in Parkinson's disease. A follow-up study of untreated patientsQ48397902
Neuropeptides and dementia.Q48404814
Substance P raises neuronal membrane excitability by reducing inward rectificationQ48479845
Neuropeptides in Alzheimer type dementiaQ48712331
Effect of Org2766, an ACTH(4–9) analogue, on recovery after bilateral transection of the fimbria fornix in the ratQ48764968
Cognitive deficits in the early stages of Parkinson's diseaseQ48800336
Modulation of cortical acetylcholine release by serotonin: the role of substance P interneuronsQ48875017
Chronic exposure to low doses of MPTP. I. Cognitive deficits in motor asymptomatic monkeysQ48951590
Age-related changes in central nervous system enkephalins and substance PQ49155003
The effects of thyrotropin-releasing hormone and scopolamine in Alzheimer's disease and normal volunteers.Q52091302
Cognitive impairments associated with early Parkinson's disease.Q52116212
Septal vasopressin modulates social memory in male rats.Q52122344
Neuropeptide substance P improves water maze performance in aged ratsQ52243839
Decrease of substance P-like immunoreactivity in the substantia nigra and pallidum of parkinsonian brainsQ64765365
Grooming behavior induced by substance PQ69055525
Trophic effect of various neuropeptides on the cultured ventral spinal cord of rat embryoQ69096610
A peptide enhancement strategy in Alzheimer's disease: pilot study with TRH-physostigmine infusionsQ70482095
Neurotrophic effects of substance P on hippocampal neurons in vitroQ71617972
A survey of substance P, somatostatin, and neurotensin levels in aging in the rat and human central nervous systemQ72660489
Age-related changes in the contents of neuropeptides in the rat brain and pituitaryQ72743921
P433issue1
P407language of work or nameEnglishQ1860
P304page(s)31-52
P577publication date2002-01-01
P1433published inCNS Neuroscience & TherapeuticsQ5013184
P1476titleS 17092: a prolyl endopeptidase inhibitor as a potential therapeutic drug for memory impairment. Preclinical and clinical studies
P478volume8

Reverse relations

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