| scholarly article | Q13442814 |
| P356 | DOI | 10.1016/S0006-291X(02)02379-3 |
| P698 | PubMed publication ID | 12372426 |
| P50 | author | Hiroaki Sakurai | Q37371428 |
| P2093 | author name string | Naoya Sato | |
| Junko Mizukami | |||
| Takahisa Sugita | |||
| Akito Nishi | |||
| Hidetaka Miyoshi | |||
| P2860 | cites work | The kinase TAK1 can activate the NIK-I kappaB as well as the MAP kinase cascade in the IL-1 signalling pathway | Q22009096 |
| TAK1 is a ubiquitin-dependent kinase of MKK and IKK | Q24291454 | ||
| IRAK-mediated translocation of TRAF6 and TAB2 in the interleukin-1-induced activation of NFkappa B | Q24291605 | ||
| TAK1 mediates the ceramide signaling to stress-activated protein kinase/c-Jun N-terminal kinase | Q24310066 | ||
| TAB1: an activator of the TAK1 MAPKKK in TGF-beta signal transduction | Q24312956 | ||
| A novel kinase cascade mediated by mitogen-activated protein kinase kinase 6 and MKK3 | Q24320233 | ||
| Receptor activator of NF-kappaB ligand (RANKL) activates TAK1 mitogen-activated protein kinase kinase kinase through a signaling complex containing RANK, TAB2, and TRAF6 | Q24537518 | ||
| Interleukin-1 (IL-1) receptor-associated kinase leads to activation of TAK1 by inducing TAB2 translocation in the IL-1 signaling pathway | Q24550984 | ||
| TAK1 mitogen-activated protein kinase kinase kinase is activated by autophosphorylation within its activation loop | Q28115673 | ||
| TAB2, a novel adaptor protein, mediates activation of TAK1 MAPKKK by linking TAK1 to TRAF6 in the IL-1 signal transduction pathway | Q28140039 | ||
| Functional interactions of transforming growth factor beta-activated kinase 1 with IkappaB kinases to stimulate NF-kappaB activation | Q28140522 | ||
| Phosphorylation-dependent activation of TAK1 mitogen-activated protein kinase kinase kinase by TAB1 | Q28145701 | ||
| Activation of the hematopoietic progenitor kinase-1 (HPK1)-dependent, stress-activated c-Jun N-terminal kinase (JNK) pathway by transforming growth factor beta (TGF-beta)-activated kinase (TAK1), a kinase mediator of TGF beta signal transduction | Q28247729 | ||
| TGF-beta-activated kinase 1 stimulates NF-kappa B activation by an NF-kappa B-inducing kinase-independent mechanism | Q28263166 | ||
| Identification of a member of the MAPKKK family as a potential mediator of TGF-beta signal transduction | Q28271470 | ||
| Mutations in the Drosophila dTAK1 gene reveal a conserved function for MAPKKKs in the control of rel/NF-kappaB-dependent innate immune responses | Q28345340 | ||
| IRAK and TAK1 are required for IL-18-mediated signaling | Q40763167 | ||
| TAK1 mediates an activation signal from toll-like receptor(s) to nuclear factor-kappaB in lipopolysaccharide-stimulated macrophages | Q40900102 | ||
| MAP kinase and Wnt pathways converge to downregulate an HMG-domain repressor in Caenorhabditis elegans | Q40944527 | ||
| p38 MAPK and NF-kappa B collaborate to induce interleukin-6 gene expression and release. Evidence for a cytoprotective autocrine signaling pathway in a cardiac myocyte model system | Q41732350 | ||
| Alternative splicing and gene structure of the transforming growth factor beta-activated kinase 1. | Q42639147 | ||
| The TAK1-NLK-MAPK-related pathway antagonizes signalling between beta-catenin and transcription factor TCF. | Q50336935 | ||
| TAK1 is activated in the myocardium after pressure overload and is sufficient to provoke heart failure in transgenic mice. | Q64979026 | ||
| P433 | issue | 5 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | NF-κB | Q411114 |
| P304 | page(s) | 1277-1281 | |
| P577 | publication date | 2002-10-01 | |
| P1433 | published in | Biochemical and Biophysical Research Communications | Q864228 |
| P1476 | title | TAK1-TAB1 fusion protein: a novel constitutively active mitogen-activated protein kinase kinase kinase that stimulates AP-1 and NF-kappaB signaling pathways | |
| P478 | volume | 297 |
| Q31126994 | "Upstream Analysis": An Integrated Promoter-Pathway Analysis Approach to Causal Interpretation of Microarray Data |
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| Q40129501 | A robust, target-driven, cell-based assay for checkpoint kinase 1 inhibitors |
| Q53244774 | Activation of Macrophages and Microglia by Interferon-γ and Lipopolysaccharide Increases Methylglyoxal Production: A New Mechanism in the Development of Vascular Complications and Cognitive Decline in Type 2 Diabetes Mellitus? |
| Q37041538 | Altered TAB1:I kappaB kinase interaction promotes transforming growth factor beta-mediated nuclear factor-kappaB activation during breast cancer progression |
| Q42957587 | An unexpected twist to the activation of IKKβ: TAK1 primes IKKβ for activation by autophosphorylation. |
| Q60920463 | Anti-Colitic Effects of Ethanol Extract of Mill. through Suppression of Pro-Inflammatory Mediators via NF-κB/STAT3 Inactivation in Dextran Sulfate Sodium-Induced Colitis Mice |
| Q28117206 | Autoactivation of transforming growth factor beta-activated kinase 1 is a sequential bimolecular process |
| Q45182335 | Critical roles of threonine 187 phosphorylation in cellular stress-induced rapid and transient activation of transforming growth factor-beta-activated kinase 1 (TAK1) in a signaling complex containing TAK1-binding protein TAB1 and TAB2. |
| Q28577795 | Cross-talk of the related bioactivity mediators in serum after injection of soluble TNF-α receptor on silicosis model of rats |
| Q51876486 | Cytokines and myelination in the central nervous system. |
| Q38560371 | Differential roles of resident microglia and infiltrating monocytes in murine CNS autoimmunity |
| Q90737605 | Dual-Specificity Phosphatase 26 Protects Against Nonalcoholic Fatty Liver Disease in Mice Through Transforming Growth Factor Beta-Activated Kinase 1 Suppression |
| Q38719199 | Ethanol Extract of Potentilla supina Linne Suppresses LPS-induced Inflammatory Responses through NF-κB and AP-1 Inactivation in Macrophages and in Endotoxic mice. |
| Q31117481 | Genetic parameters and genome-wide association study of hyperpigmentation of the visceral peritoneum in chickens |
| Q33756614 | HIV-1 Vpr stimulates NF-κB and AP-1 signaling by activating TAK1. |
| Q34117399 | Identification and functional characterization of novel phosphorylation sites in TAK1-binding protein (TAB) 1. |
| Q33619331 | Inflammatory mediator TAK1 regulates hair follicle morphogenesis and anagen induction shown by using keratinocyte-specific TAK1-deficient mice |
| Q42385640 | Live imaging of transforming growth factor-β activated kinase 1 activation in Lewis lung carcinoma 3LL cells implanted into syngeneic mice and treated with polyinosinic:polycytidylic acid |
| Q41894880 | Phosphorylation of Thr-178 and Thr-184 in the TAK1 T-loop is required for interleukin (IL)-1-mediated optimal NFkappaB and AP-1 activation as well as IL-6 gene expression. |
| Q38828740 | Plasma miR-940 may serve as a novel biomarker for gastric cancer |
| Q38872980 | Porcine reproductive and respiratory syndrome virus (PRRSV) up-regulates IL-8 expression through TAK-1/JNK/AP-1 pathways |
| Q39096576 | Post-Translational Modifications of the TAK1-TAB Complex. |
| Q34984571 | Procarcinogenic effects of cyclosporine A are mediated through the activation of TAK1/TAB1 signaling pathway |
| Q39473622 | Rhesus monkey TRIM5α represses HIV-1 LTR promoter activity by negatively regulating TAK1/TAB1/TAB2/TAB3-complex-mediated NF-κB activation |
| Q47871261 | Role for TAK1 in cigarette smoke-induced proinflammatory signaling and IL-8 release by human airway smooth muscle cells |
| Q36470294 | Sequence-specific activation of TAK1-D by short double-stranded RNAs induces apoptosis in NCI-H460 cells |
| Q39602471 | Stercurensin inhibits nuclear factor-κB-dependent inflammatory signals through attenuation of TAK1-TAB1 complex formation |
| Q30465209 | TAK1 expression in the cochlea: a specific marker for adult supporting cells |
| Q46808873 | TAK1-mediated transcriptional activation of CD28-responsive element and AP-1-binding site within the IL-2 promoter in Jurkat T cells |
| Q21092160 | TRAF6 autoubiquitination-independent activation of the NFkappaB and MAPK pathways in response to IL-1 and RANKL |
| Q64917799 | The MAP3K7-mTOR Axis Promotes the Proliferation and Malignancy of Hepatocellular Carcinoma Cells. |
| Q34107219 | Transforming growth factor (TGF)-β-activated kinase 1 (TAK1) activation requires phosphorylation of serine 412 by protein kinase A catalytic subunit α (PKACα) and X-linked protein kinase (PRKX). |
| Q35221840 | Transforming growth factor beta-activated kinase 1 is a key mediator of ovine follicle-stimulating hormone beta-subunit expression |
| Q35178122 | c-Jun N-terminal kinase phosphorylates DCP1a to control formation of P bodies |
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