Multifunctional strands in tight junctions

scientific article (publication date: April 2001)

Multifunctional strands in tight junctions is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

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P6179Dimensions Publication ID1044036068
P356DOI10.1038/35067088
P3181OpenCitations bibliographic resource ID3316782
P698PubMed publication ID11283726
P5875ResearchGate publication ID12049428

P50authorMikio FuruseQ59694378
P2093author name stringItoh M
Tsukita S
P2860cites workClaudin multigene family encoding four-transmembrane domain protein components of tight junction strandsQ22008687
Paracellin-1, a renal tight junction protein required for paracellular Mg2+ resorptionQ22010191
Ca(2+)-independent cell-adhesion activity of claudins, a family of integral membrane proteins localized at tight junctionsQ22010607
Interaction of the tumor suppressor PTEN/MMAC with a PDZ domain of MAGI3, a novel membrane-associated guanylate kinaseQ22253438
Evidence for regulation of the PTEN tumor suppressor by a membrane-localized multi-PDZ domain containing scaffold protein MAGI-2Q22253866
Vascular endothelial junction-associated molecule, a novel member of the immunoglobulin superfamily, is localized to intercellular boundaries of endothelial cellsQ22253974
huASH1 protein, a putative transcription factor encoded by a human homologue of the Drosophila ash1 gene, localizes to both nuclei and cell-cell tight junctionsQ22254287
The cell-polarity protein Par6 links Par3 and atypical protein kinase C to Cdc42Q22254751
Identification, characterization, and precise mapping of a human gene encoding a novel membrane-spanning protein from the 22q11 region deleted in velo-cardio-facial syndromeQ24311578
The tight junction protein ZO-1 is homologous to the Drosophila discs-large tumor suppressor protein of septate junctionsQ24316928
Symplekin, a novel type of tight junction plaque proteinQ24317634
The 220-kD protein colocalizing with cadherins in non-epithelial cells is identical to ZO-1, a tight junction-associated protein in epithelial cells: cDNA cloning and immunoelectron microscopyQ24336066
A small rab GTPase is distributed in cytoplasmic vesicles in non polarized cells but colocalizes with the tight junction marker ZO-1 in polarized epithelial cellsQ24336878
Occludin: a novel integral membrane protein localizing at tight junctionsQ24657666
Cingulin contains globular and coiled-coil domains and interacts with ZO-1, ZO-2, ZO-3, and myosinQ24670442
Interspecies diversity of the occludin sequence: cDNA cloning of human, mouse, dog, and rat-kangaroo homologuesQ24671949
Direct association of occludin with ZO-1 and its possible involvement in the localization of occludin at tight junctionsQ24672971
Expression and polarized targeting of a rab3 isoform in epithelial cellsQ24673448
Involvement of ZO-1 in Cadherin-based Cell Adhesion through Its Direct Binding to α Catenin and Actin FilamentsQ24678389
Direct binding of three tight junction-associated MAGUKs, ZO-1, ZO-2, and ZO-3, with the COOH termini of claudinsQ24682136
Junctional adhesion molecule, a novel member of the immunoglobulin superfamily that distributes at intercellular junctions and modulates monocyte transmigrationQ24682572
Claudin-1 and -2: novel integral membrane proteins localizing at tight junctions with no sequence similarity to occludinQ24682664
Endothelial claudin: claudin-5/TMVCF constitutes tight junction strands in endothelial cellsQ24682677
An atypical PKC directly associates and colocalizes at the epithelial tight junction with ASIP, a mammalian homologue of Caenorhabditis elegans polarity protein PAR-3Q24682973
ZO-3, a novel member of the MAGUK protein family found at the tight junction, interacts with ZO-1 and occludinQ24683294
Manner of interaction of heterogeneous claudin species within and between tight junction strandsQ24683327
Molecular cloning and functional characterization of the receptor for Clostridium perfringens enterotoxinQ24683859
Characterization of ZO-2 as a MAGUK family member associated with tight as well as adherens junctions with a binding affinity to occludin and alpha cateninQ28137655
Interaction of junctional adhesion molecule with the tight junction components ZO-1, cingulin, and occludinQ28139702
Identification of a 160-kDa polypeptide that binds to the tight junction protein ZO-1.Q37487429
Redistribution of surface macromolecules in dissociated epithelial cellsQ39408257
Breaking through the tight junction barrierQ40798811
A mammalian PAR-3-PAR-6 complex implicated in Cdc42/Rac1 and aPKC signalling and cell polarityQ40862977
Oncogenic Raf-1 disrupts epithelial tight junctions via downregulation of occludinQ40898868
Localization of membrane-associated guanylate kinase (MAGI)-1/BAI-associated protein (BAP) 1 at tight junctions of epithelial cellsQ40908844
Clostridium perfringens enterotoxin fragment removes specific claudins from tight junction strands: Evidence for direct involvement of claudins in tight junction barrier.Q40925316
Involvement of Galphai2 in the maintenance and biogenesis of epithelial cell tight junctionsQ41016210
Possible involvement of phosphorylation of occludin in tight junction formationQ41104367
Routes and mechanism of fluid transport by epitheliaQ41748248
Regulation of the movement of solutes across tight junctionsQ41748263
Claudin-11/OSP-based tight junctions of myelin sheaths in brain and Sertoli cells in testisQ42079092
Claudins regulate the intestinal barrier in response to immune mediatorsQ42488651
A single gene product, claudin-1 or -2, reconstitutes tight junction strands and recruits occludin in fibroblastsQ42796669
Morphological factors influencing transepithelial permeability: A model for the resistance of theZonula OccludensQ43798217
Transbilayer phospholipid asymmetry and its maintenance in the membrane of influenza virusQ45881746
Synaptic PDZ domain-containing proteins.Q52036660
Homophilic interaction of junctional adhesion molecule.Q52581140
Phospholipid topology and flip-flop in intestinal brush-border membraneQ56775309
Evidence for the lipidic nature of tight junction strandsQ59087871
Membrane asymmetry in epithelia: is the tight junction a barrier to diffusion in the plasma membrane?Q59093204
Lack of correlation between tight junction morphology and permeability properties in developing choroid plexusQ59095848
Plasma membrane and mucosal glycosphingolipids in the rat intestineQ69565101
Phospholipids and cholesterol in brush border and basolateral membranes from rat intestinal mucosaQ71027672
Association of junctional adhesion molecule with calcium/calmodulin-dependent serine protein kinase (CASK/LIN-2) in human epithelial caco-2 cellsQ28140550
Integrin signalingQ28142010
MAGI-1, a membrane-associated guanylate kinase with a unique arrangement of protein-protein interaction domainsQ28256306
Occludin is concentrated at tight junctions of mouse/rat but not human/guinea pig Sertoli cells in testesQ28272596
Sec6/8 complex is recruited to cell-cell contacts and specifies transport vesicle delivery to the basal-lateral membrane in epithelial cellsQ28273946
The tight junction protein ZO-1 establishes a link between the transmembrane protein occludin and the actin cytoskeletonQ28287040
Identification of ZO-1: a high molecular weight polypeptide associated with the tight junction (zonula occludens) in a variety of epitheliaQ28299935
CNS myelin and sertoli cell tight junction strands are absent in Osp/claudin-11 null miceQ28512612
Junctional complexes in various epitheliaQ29620435
The tight junction protein ZO-1 and an interacting transcription factor regulate ErbB-2 expressionQ30175138
Isolation and Characterization of Transcripts Induced by Androgen Withdrawal and Apoptotic Cell Death in the Rat Ventral ProstateQ33269561
Occludin and claudins in tight-junction strands: leading or supporting players?Q33659718
Structural and signalling molecules come together at tight junctionsQ33744924
Pores in the wall: claudins constitute tight junction strands containing aqueous poresQ33881242
Mutations in the gene encoding tight junction claudin-14 cause autosomal recessive deafness DFNB29.Q33932144
Tight junction dynamics: is paracellular transport regulated?Q34049445
Fracture faces of zonulae occludentes from "tight" and "leaky" epitheliaQ34051800
A synthetic peptide corresponding to the extracellular domain of occludin perturbs the tight junction permeability barrierQ34064091
Cingulin, a new peripheral component of tight junctionsQ34172366
Isolation and characterization of a novel oligodendrocyte-specific proteinQ34396138
Occludin 1B, a variant of the tight junction protein occludinQ34684155
Restoration of tight junction structure and barrier function by down-regulation of the mitogen-activated protein kinase pathway in ras-transformed Madin-Darby canine kidney cellsQ34690508
Complex phenotype of mice lacking occludin, a component of tight junction strands.Q34781594
Regulation of cell surface polarity from bacteria to mammalsQ35532352
Redistribution of membrane proteins in isolated mouse intestinal epithelial cellsQ36201647
Formation of the apical pole of epithelial (Madin-Darby canine kidney) cells: polarity of an apical protein is independent of tight junctions while segregation of a basolateral marker requires cell-cell interactionsQ36216030
Tight junction structure and ZO-1 content are identical in two strains of Madin-Darby canine kidney cells which differ in transepithelial resistanceQ36221153
Monoclonal antibody 7H6 reacts with a novel tight junction-associated protein distinct from ZO-1, cingulin and ZO-2.Q36232347
Assembly of the tight junction: the role of diacylglycerolQ36233397
Molecular characterization and tissue distribution of ZO-2, a tight junction protein homologous to ZO-1 and the Drosophila discs-large tumor suppressor proteinQ36233880
Functional dissociation of paracellular permeability and transepithelial electrical resistance and disruption of the apical-basolateral intramembrane diffusion barrier by expression of a mutant tight junction membrane proteinQ36237286
Structural and functional regulation of tight junctions by RhoA and Rac1 small GTPasesQ36256190
Occludin-deficient embryonic stem cells can differentiate into polarized epithelial cells bearing tight junctionsQ36289162
Structure of tight junctions in epithelia with different permeabilityQ37460393
P433issue4
P407language of work or nameEnglishQ1860
P304page(s)285-293
P577publication date2001-04-01
P1433published inNature Reviews Molecular Cell BiologyQ1573120
P1476titleMultifunctional strands in tight junctions
P478volume2

Reverse relations

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Q28212968Cloning of the human claudin-2 5'-flanking region revealed a TATA-less promoter with conserved binding sites in mouse and human for caudal-related homeodomain proteins and hepatocyte nuclear factor-1alpha
Q89736885Clostridium perfringens enterotoxin induces claudin-4 to activate YAP in oral squamous cell carcinomas
Q40793623Comparative biochemical and immunocytochemical studies reveal differences in the effects of Clostridium perfringens enterotoxin on polarized CaCo-2 cells versus Vero cells
Q38476496Comparative mapping of human claudin-1 (CLDN1) in great apes
Q57840006Comparative tight junction protein expressions in colonic Crohn’s disease, ulcerative colitis, and tuberculosis: a new perspective
Q44437836Comparison of ultrastructure, tight junction-related protein expression and barrier function of human corneal epithelial cells cultivated on amniotic membrane with and without air-lifting
Q34191705Complex inheritance of familial hypercholanemia with associated mutations in TJP2 and BAAT.
Q35188696Composition and function of PDZ protein complexes during cell polarization
Q26861369Conceptual barriers to understanding physical barriers
Q57398142Confirmation of the origin of NISCH syndrome
Q40230721Connexin 26 expression prevents down-regulation of barrier and fence functions of tight junctions by Na+/K+-ATPase inhibitor ouabain in human airway epithelial cell line Calu-3.
Q36849393Connexins induce and maintain tight junctions in epithelial cells
Q50505471Connexins, E-cadherin, Claudin-7 and β-catenin transiently form junctional nexuses during the post-natal mammary gland development.
Q50320976Cow's Milk and Immune Function in the Respiratory Tract: Potential Mechanisms
Q37085037Cross-talk among integrin, cadherin, and growth factor receptor: roles of nectin and nectin-like molecule.
Q33841456Cross-talk between tight and anchoring junctions-lesson from the testis
Q28079482Crosstalk between Inflammation and ROCK/MLCK Signaling Pathways in Gastrointestinal Disorders with Intestinal Hyperpermeability
Q40277231Crucial roles of Sp1 and epigenetic modifications in the regulation of the CLDN4 promoter in ovarian cancer cells
Q49997335Cryptosporidium parvum disrupts intestinal epithelial barrier function via altering expression of key tight junction and adherens junction proteins
Q51692196Cryptosporidium parvum increases intestinal permeability through interaction with epithelial cells and IL-1β and TNFα released by inflammatory monocytes.
Q27690052Crystal structure of a claudin provides insight into the architecture of tight junctions
Q39384984Curcumin ameliorates hydrogen peroxide-induced epithelial barrier disruption by upregulating heme oxygenase-1 expression in human intestinal epithelial cells
Q34994241Curcumin prevents replication of respiratory syncytial virus and the epithelial responses to it in human nasal epithelial cells
Q50116101Curcumin-mediated regulation of intestinal barrier function: The mechanism underlying its beneficial effects.
Q48168395Cyclic AMP induces phosphorylation of claudin-5 immunoprecipitates and expression of claudin-5 gene in blood-brain-barrier endothelial cells via protein kinase A-dependent and -independent pathways
Q34033538Cytoskeletal regulation of epithelial barrier function during inflammation
Q36404914Cytoskeleton assembly at endothelial cell-cell contacts is regulated by alphaII-spectrin-VASP complexes
Q38755548DNA methylation of claudin-6 promotes breast cancer cell migration and invasion by recruiting MeCP2 and deacetylating H3Ac and H4Ac
Q41418721DT-13 Ameliorates TNF-α-Induced Vascular Endothelial Hyperpermeability via Non-Muscle Myosin IIA and the Src/PI3K/Akt Signaling Pathway
Q34048824Deafness in occludin-deficient mice with dislocation of tricellulin and progressive apoptosis of the hair cells
Q35531685Decay-accelerating factor binding determines the entry route of echovirus 11 in polarized epithelial cells.
Q51090200Decreased interaction between ZO-1 and occludin is involved in alteration of tight junctions in transplanted epiphora submandibular glands.
Q64126689Deficiency of Stomach-Type Claudin-18 in Mice Induces Gastric Tumor Formation Independent of H. Pylori Infection
Q36678082Deficiency of zonula occludens-1 causes embryonic lethal phenotype associated with defected yolk sac angiogenesis and apoptosis of embryonic cells
Q35105219Dehydro-alpha-lapachone, a plant product with antivascular activity.
Q24310946Density-enhanced phosphatase 1 regulates phosphorylation of tight junction proteins and enhances barrier function of epithelial cells
Q33670957Dentin sialoprotein facilitates dental mesenchymal cell differentiation and dentin formation
Q40500818Depletion of Caco-2 cell cholesterol disrupts barrier function by altering the detergent solubility and distribution of specific tight-junction proteins
Q38663515Desmoglein 2 regulates the intestinal epithelial barrier via p38 mitogen-activated protein kinase
Q38959847Desmoglein-1 regulates esophageal epithelial barrier function and immune responses in eosinophilic esophagitis.
Q37973313Determinants of colonic barrier function in inflammatory bowel disease and potential therapeutics
Q33442189Development and characterization of a human single-chain antibody fragment against claudin-3: a novel therapeutic target in ovarian and uterine carcinomas
Q45044075Developmental regulation of claudin localization by fetal alveolar epithelial cells
Q34170173Diagnostic value of claudin-4 marker in pleural and peritoneal effusion cytology: Does it differentiate between metastatic adenocarcinoma and reactive mesothelial cells?
Q50220255Dietary nitrite induces occludin nitration in the stomach
Q27022611Dietary proteins as determinants of metabolic and physiologic functions of the gastrointestinal tract
Q61813817Differential Transcriptome Responses to Aflatoxin B₁ in the Cecal Tonsil of Susceptible and Resistant Turkeys
Q24628554Differential distribution of tight junction proteins suggests a role for tanycytes in blood-hypothalamus barrier regulation in the adult mouse brain
Q28509306Differential expression and subcellular localization of claudin-7, -8, -12, -13, and -15 along the mouse intestine
Q35613198Differential expression of claudin family proteins in mouse ovarian serous papillary epithelial adenoma in aging FSH receptor-deficient mutants
Q41436529Differential expression of claudin tight junction proteins in the human cortical nephron
Q61773593Differential expression of genes encoding tight junction proteins in colorectal cancer: frequent dysregulation of claudin-1, -8 and -12
Q37402174Differential pathways of claudin oligomerization and integration into tight junctions
Q40643747Differential regulation of junctional complex assembly in renal epithelial cell lines
Q45753289Differential role of Rho GTPases in intestinal epithelial barrier regulation in vitro
Q33841357Differential roles for actin polymerization and a myosin II motor in assembly of the epithelial apical junctional complex
Q27325458Differential sensitivity of epithelial cells to extracellular matrix in polarity establishment
Q90647498Direct Cell⁻Cell Interactions in the Endometrium and in Endometrial Pathophysiology
Q28201973Direct binding of cell polarity protein PAR-3 to cell-cell adhesion molecule nectin at neuroepithelial cells of developing mouse
Q37412670Discovering the molecular components of intercellular junctions--a historical view.
Q45337463Disruption of ZO-1/claudin-4 interaction in relation to inflammatory responses in methotrexate-induced intestinal mucositis
Q36699646Disruption of claudin-18 diminishes ovariectomy-induced bone loss in mice
Q40186985Disruption of epithelial barrier by quorum-sensing N-3-(oxododecanoyl)-homoserine lactone is mediated by matrix metalloproteinases.
Q28580941Dissociation and dispersion of claudin-3 from the tight junction could be one of the most sensitive indicators of reflux esophagitis in a rat model of the disease
Q95383337Distinct behavior of claudin-3 and -4 around lactation period in mammary alveolus in mice
Q24674840Distinct claudins and associated PDZ proteins form different autotypic tight junctions in myelinating Schwann cells
Q54682146Distinct expression patterns of claudin-1 and claudin-4 in intraductal papillary-mucinous tumors of the pancreas.
Q58199721Distinct molecular composition of blood and lymphatic vascular endothelial cell junctions establishes specific functional barriers within the peripheral lymph node
Q34220077Distinct roles of Rab3B and Rab13 in the polarized transport of apical, basolateral, and tight junctional membrane proteins to the plasma membrane
Q28255146Distribution of the tight junction proteins ZO-1, occludin, and claudin-4, -8, and -12 in bladder epithelium
Q30437791Distribution of tight junction proteins in adult human salivary glands.
Q33914754Divergent expression of claudin -1, -3, -4, -5 and -7 in developing human lung
Q48120261Diversification of epithelial adherens junctions with independent reductive changes in cadherin form: identification of potential molecular synapomorphies among bilaterians
Q37102460Dose-dependent role of claudin-1 in vivo in orchestrating features of atopic dermatitis
Q35666010Down Regulation of CLDND1 Induces Apoptosis in Breast Cancer Cells
Q38945099Down regulated expression of Claudin-1 and Claudin-5 and up regulation of β-catenin: association with human glioma progression
Q49181173Down-regulation of Claudin-2 Expression and Proliferation by Epigenetic Inhibitors in Human Lung Adenocarcinoma A549 Cells
Q35000704Down-regulation of claudin-18 is associated with the proliferative and invasive potential of gastric cancer at the invasive front
Q53188874Down-regulation of claudin-3 is associated with proliferative potential in early gastric cancers.
Q40383109Down-regulation of survival signaling through MAPK and Akt in occludin-deficient mouse hepatocytes in vitro
Q59340601Downregulation of CLDN7 due to promoter hypermethylation is associated with human clear cell renal cell carcinoma progression and poor prognosis
Q39505682Downregulation of tight junction-associated MARVEL protein marvelD3 during epithelial-mesenchymal transition in human pancreatic cancer cells
Q35068853Downsloping high-frequency hearing loss due to inner ear tricellular tight junction disruption by a novel ILDR1 mutation in the Ig-like domain
Q37956222Drosophila as a model for epithelial tube formation
Q44576208Duodenal villous hypertrophy and upregulation of claudin-15 protein expression in lactating rats
Q30477728Dynamic behavior of paired claudin strands within apposing plasma membranes
Q37135563Dynamic purine signaling and metabolism during neutrophil-endothelial interactions
Q40454670Dynamics of the Ins(1,4,5)P3 receptor during polarization of MDCK cells.
Q92482674Dysregulated claudin-5 cycling in the inner retina causes retinal pigment epithelial cell atrophy
Q48110584E-cadherin regulators are differentially expressed in the epithelium and stroma of keratocystic odontogenic tumors.
Q35653917E/N-cadherin switch mediates cancer progression via TGF-β-induced epithelial-to-mesenchymal transition in extrahepatic cholangiocarcinoma
Q43154880EFA6 facilitates the assembly of the tight junction by coordinating an Arf6-dependent and -independent pathway
Q36779763EFA6, exchange factor for ARF6, regulates the actin cytoskeleton and associated tight junction in response to E-cadherin engagement.
Q36483466Early embryonic lethality of mice lacking ZO-2, but Not ZO-3, reveals critical and nonredundant roles for individual zonula occludens proteins in mammalian development
Q92000548Ectopic expression of CLDN2 in podocytes is associated with childhood onset nephrotic syndrome
Q41911628Effect of Glucagon-like Peptide 2 on Tight Junction in Jejunal Epithelium of Weaned Pigs though MAPK Signaling Pathway
Q36951885Effect of cyclic AMP on barrier function of human lymphatic microvascular tubes
Q45114649Effect of estradiol on mouse uterine epithelial cell transepithelial resistance (TER).
Q30488665Effect of focused ultrasound applied with an ultrasound contrast agent on the tight junctional integrity of the brain microvascular endothelium
Q40510988Effect of human rhinovirus infection on airway epithelium tight junction protein disassembly and transepithelial permeability.
Q39542097Effects of Clostridium perfringens enterotoxin via claudin-4 on normal human pancreatic duct epithelial cells and cancer cells
Q35958793Effects of acute intra-abdominal hypertension on multiple intestinal barrier functions in rats
Q60301249Effects of dietary supplementation with on the performance, intestinal physical barrier function, and the expression of NOD-like receptors in weaned piglets
Q34259654Effects of ethanol and acetaldehyde on tight junction integrity: in vitro study in a three dimensional intestinal epithelial cell culture model
Q36917520Effects of genetically modified T2A-1 rice on the GI health of rats after 90-day supplement
Q34277090Effects of human Parvovirus B19 and Bocavirus VP1 unique region on tight junction of human airway epithelial A549 cells
Q33879992Effects of phenol on barrier function of a human intestinal epithelial cell line correlate with altered tight junction protein localization
Q46639019Effects of transdifferentiation and EGF on claudin isoform expression in alveolar epithelial cells
Q37303018Efficacy and safety evaluation of claudin-4-targeted antitumor therapy using a human and mouse cross-reactive monoclonal antibody.
Q46584676Efficient in vivo microRNA targeting of liver metastasis
Q42643703Egfl7 knockdown causes defects in the extension and junctional arrangements of endothelial cells during zebrafish vasculogenesis
Q34482550Electrolyte transport in the mammalian colon: mechanisms and implications for disease
Q47127303Elevated expression of JAM-A promotes neoplastic properties of lung adenocarcinoma
Q38195730Emerging micro- and nanotechnology based synthetic approaches for insulin delivery
Q37930997Emerging role for epithelial polarity proteins of the Crumbs family as potential tumor suppressors
Q37225107Emerging roles of claudins in human cancer
Q37654826Endocytosis and recycling of tight junction proteins in inflammation
Q42861316Endocytosis of E-cadherin regulated by Rac and Cdc42 small G proteins through IQGAP1 and actin filaments
Q34786013Endocytosis of Epithelial Apical Junctional Proteins by a Clathrin-mediated Pathway into a Unique Storage Compartment
Q37175096Endometrial claudin-4 and leukemia inhibitory factor are associated with assisted reproduction outcome
Q26773097Endothelial Barrier and Its Abnormalities in Cardiovascular Disease
Q51171171Endothelial Tight Junctions Are Opened in Cholinergic-Evoked Salivation In Vivo.
Q40512855Endothelial adhesion molecule ESAM binds directly to the multidomain adaptor MAGI-1 and recruits it to cell contacts
Q53942981Endothelial barrier strengthening by activation of focal adhesion kinase.
Q24324232Endothelial cell barrier impairment induced by glioblastomas and transforming growth factor beta2 involves matrix metalloproteinases and tight junction proteins
Q35741007Endothelial cell-cell junctions: happy together
Q39696505Endothelial dysfunction and claudin 5 regulation during acrolein-induced lung injury.
Q37955886Endothelial dysfunction as a cellular mechanism for vascular failure
Q30734754Endothelial β-Catenin Signaling Is Required for Maintaining Adult Blood-Brain Barrier Integrity and Central Nervous System Homeostasis
Q58748664Engineering and monitoring cellular barrier models
Q39469923Enhancement of cell-cell contact by claudin-4 in renal epithelial Madin-Darby canine kidney cells
Q57175872Enhancing glucose flux into sweat by increasing paracellular permeability of the sweat gland
Q39139171Enteric Pathogens and Their Toxin-Induced Disruption of the Intestinal Barrier through Alteration of Tight Junctions in Chickens.
Q24596978Enteric infection meets intestinal function: how bacterial pathogens cause diarrhoea
Q37970075Enterocytes' tight junctions: From molecules to diseases
Q35112967Enteroendocrine cells are specifically marked by cell surface expression of claudin-4 in mouse small intestine
Q35890719Enteropathogenic E. coli-induced barrier function alteration is not a consequence of host cell apoptosis
Q41851259Enteropathogenic Escherichia coli, Shigella flexneri, and Listeria monocytogenes recruit a junctional protein, zonula occludens-1, to actin tails and pedestals.
Q50794460EpCAM contributes to formation of functional tight junction in the intestinal epithelium by recruiting claudin proteins.
Q40620861Epidermal Growth Factor Receptor Activation Differentially Regulates Claudin Expression and Enhances Transepithelial Resistance in Madin-Darby Canine Kidney Cells
Q37980290Epidermal barrier dysfunction and cutaneous sensitization in atopic diseases
Q37452073Epidermal cell turnover across tight junctions based on Kelvin's tetrakaidecahedron cell shape
Q39527005Epidermal growth factor increases clathrin-dependent endocytosis and degradation of claudin-2 protein in MDCK II cells
Q39356689Epidermal growth factor modulates claudins and tight junctional functions in ovarian cancer cell lines
Q52580604Epigenetic silencing of claudin-6 promotes anchorage-independent growth of breast carcinoma cells.
Q38193098Epithelial adhesive junctions
Q37808213Epithelial barrier and antigen uptake in lymphoepithelium of human adenoids
Q38562421Epithelial barrier and oral bacterial infection
Q38294528Epithelial barrier function and immunity in asthma.
Q36079848Epithelial cells in the female reproductive tract: a central role as sentinels of immune protection
Q35971814Epithelial-mesenchymal transition in ovarian carcinoma
Q47124460Epithelial-to-mesenchymal transition in gallbladder cancer: from clinical evidence to cellular regulatory networks
Q45841687Esophageal barrier function and tight junction expression in healthy subjects and patients with gastroesophageal reflux disease: functionality of esophageal mucosa exposed to bile salt and trypsin in vitro
Q34522245Establishing cell polarity in development
Q40528997Establishment and characterization of cultured epithelial cells lacking expression of ZO-1.
Q36959343Establishment of a simplified in vitro porcine blood-brain barrier model with high transendothelial electrical resistance
Q34117779Establishment of an in vitro brain barrier epithelial transport system for pharmacological and toxicological study
Q36681213Estrogen decrease in tight junctional resistance involves matrix-metalloproteinase-7-mediated remodeling of occludin
Q34129691Evidence for a functional interaction between cingulin and ZO-1 in cultured cells
Q37710221Evidence for intestinal chloride secretion
Q30252163Evidence for the effects of yogurt on gut health and obesity.
Q36974522Evidence that membrane rafts are not required for the action of Clostridium perfringens enterotoxin
Q46365946Evolutionarily Conserved Roles for Blood-Brain Barrier Xenobiotic Transporters in Endogenous Steroid Partitioning and Behavior
Q48215330Exclusion from spheroid formation identifies loss of essential cell-cell adhesion molecules in colon cancer cells.
Q37215871Exploring tight junction alteration using double fluorescent probe combination of lanthanide complex with gold nanoclusters
Q47336358Exposure to cigarette smoke extract and lipopolysaccharide modifies cytoskeleton organization in bronchial epithelial cells.
Q28593224Expression and distribution of ZO‐3, a tight junction MAGUK protein, in mouse tissues
Q52620194Expression and distribution of symplekin regulates the assembly and function of the epithelial tight junction.
Q54692519Expression and function of tight junctions in the crypt epithelium of human palatine tonsils.
Q54701927Expression and localization of tricellulin in human nasal epithelial cells in vivo and in vitro.
Q33943052Expression and phylogeny of claudins in vertebrate primordia
Q40741647Expression and targeting of the tight junction protein CLDN1 in CLDN1-negative human breast tumor cells
Q39684300Expression of Claudin-2 in intestinal metaplastic mucosa of Cdx2-transgenic mouse stomach.
Q48681010Expression of ZO-1 and occludin at mRNA and protein level during preimplantation development of the pig parthenogenetic diploids
Q42292631Expression of apical junction complex proteins in colorectal mucosa of miniature dachshunds with inflammatory colorectal polyps.
Q33686147Expression of claudin 1, 4 and 7 in thyroid neoplasms
Q42079691Expression of claudin-1 and -7 in clear cell renal cell carcinoma and its clinical significance
Q42466916Expression of claudin-5 in hepatoid gland biopsies
Q36095370Expression of claudin-5, -7, -8 and -9 in cervical carcinoma tissues and adjacent non-neoplastic tissues
Q38308261Expression of claudin7 is tightly associated with epithelial structures in synovial sarcomas and regulated by an Ets family transcription factor, ELF3.
Q36619284Expression of claudins -2 and -4 and cingulin is coordinated with the start of stratification and differentiation in corneal epithelial cells: retinoic acid reversibly disrupts epithelial barrier.
Q34745325Expression of tight junction proteins in epithelium including Ck20-positive M-like cells of human adenoids in vivo and in vitro
Q30437572Expression of tight-junction protein claudin-7 is an early event in gastric tumorigenesis
Q43454492Expression of tight-junction-associated proteins in human gastric cancer: downregulation of claudin-4 correlates with tumor aggressiveness and survival
Q53580829Expression pattern of adhesion molecules (E-cadherin, alpha-, beta-, gamma-catenin and claudin-7), their influence on survival in primary breast carcinoma, and their corresponding axillary lymph node metastasis.
Q42512232Expression pattern of testicular claudin-11 in infertile men.
Q52087577Expression patterns of claudin family of tight junction membrane proteins in developing mouse submandibular gland.
Q79680779Expression patterns of claudin family of tight-junction proteins in the mouse prostate
Q48141048Expression patterns of claudins in patients with triple-negative breast cancer are associated with nodal metastasis and worse outcome
Q28236557Expression patterns of claudins, tight junction adhesion molecules, in the inner ear
Q37338056Expression transformation of claudin-1 in the process of gastric adenocarcinoma invasion
Q37363476Expression, localization, and function of junctional adhesion molecule-C (JAM-C) in human retinal pigment epithelium
Q35574015Extensive expansion of the claudin gene family in the teleost fish, Fugu rubripes
Q36350830Eya1 protein phosphatase regulates tight junction formation in lung distal epithelium
Q35864628F-actin binding protein, anillin, regulates integrity of intercellular junctions in human epithelial cells
Q35846780FH535 inhibited metastasis and growth of pancreatic cancer cells
Q37134799FTY720-induced human pulmonary endothelial barrier enhancement is mediated by c-Abl
Q37058180Family-wide investigation of PDZ domain-mediated protein-protein interactions implicates β-catenin in maintaining the integrity of tight junctions.
Q35109357Fibroblast growth factor-peptide improves barrier function and proliferation in human keratinocytes after radiation
Q54290216Fish oil enhances intestinal integrity and inhibits TLR4 and NOD2 signaling pathways in weaned pigs after LPS challenge.
Q40054817Formation of aberrant TJ strands by overexpression of claudin-15 in MDCK II cells
Q30854657Fractionation of the epithelial apical junctional complex: reassessment of protein distributions in different substructures
Q64902957Frequent CLDN18-ARHGAP fusion in highly metastatic diffuse-type gastric cancer with relatively early onset.
Q36568772From fate to function: the Drosophila trachea and salivary gland as models for tubulogenesis
Q41192332Function of the membrane water channel aquaporin-5 in the salivary gland
Q35150365Functional analysis of tight junctions
Q39651925Functional complexes between YAP2 and ZO-2 are PDZ domain-dependent, and regulate YAP2 nuclear localization and signalling
Q37080750Functional effectiveness of the blood-brain barrier to small water-soluble molecules in developing and adult opossum (Monodelphis domestica)
Q24676415Functionally specialized junctions between endothelial cells of lymphatic vessels
Q37783437Functions of Claudin Tight Junction Proteins and Their Complex Interactions in Various Physiological Systems
Q24319756GEF-H1 mediated control of NOD1 dependent NF-kappaB activation by Shigella effectors
Q30164599Galpha12 regulates epithelial cell junctions through Src tyrosine kinases
Q42493339Gap junctions mediate glucose transport between GLUT1-positive and -negative cells in the spiral limbus of the rat cochlea
Q34622776Gastric and intestinal claudin expression at the invasive front of gastric carcinoma
Q34520959Gastrointestinal mucosal barrier function and diseases.
Q56772548Gastrointestinal response and endotoxemia during intense exercise in hot and cool environments
Q37202093Gene Expression Profiling Reveals Functional Specialization along the Intestinal Tract of a Carnivorous Teleostean Fish (Dicentrarchus labrax)
Q40691915Gene expression of the tight junction protein occludin includes differential splicing and alternative promoter usage
Q51581930Gene expression profiling in a mouse model of Helicobacter-induced gastric cancer.
Q35353951Genetic ablation of afadin causes mislocalization and deformation of Paneth cells in the mouse small intestinal epithelium
Q35154231Genetic analysis of genes related to tight junction function in the Korean population with non-syndromic hearing loss
Q30540948Germ cell migration across Sertoli cell tight junctions
Q52606336Glia-induced reversible disruption of blood-brain barrier integrity and neuropathological response of the neurovascular unit.
Q42013569Gliotactin, a novel marker of tricellular junctions, is necessary for septate junction development in Drosophila
Q26853743Glucocorticoids and endothelial cell barrier function
Q57477161Glutamate alleviates intestinal injury, maintains mTOR and suppresses TLR4 and NOD signaling pathways in weanling pigs challenged with lipopolysaccharide
Q38782324Glycine Regulates Expression and Distribution of Claudin-7 and ZO-3 Proteins in Intestinal Porcine Epithelial Cells
Q37843684Good fences make good neighbors: Gastrointestinal mucosal structure
Q36517183Group A Streptococcus exploits human plasminogen for bacterial translocation across epithelial barrier via tricellular tight junctions.
Q39396702Guanine nucleotide-binding protein Gαi2: a new partner of claudin-5 that regulates tight junction integrity in human brain endothelial cells
Q90468267Guanylate binding protein-1-mediated epithelial barrier in human salivary gland duct epithelium
Q37488181HGF signaling regulates Claudin-3 dynamics through its C-terminal tyrosine residues
Q43496324HIV-1 Tat protein alters tight junction protein expression and distribution in cultured brain endothelial cells
Q47802370HLA-DR- and CD11c-positive dendritic cells penetrate beyond well-developed epithelial tight junctions in human nasal mucosa of allergic rhinitis
Q91865067Haptoglobin genotype and gut barrier-related complications of allogeneic hematopoietic cell transplantation
Q47324996HbAHP-25 attenuates HIV-1 gp120 mediated inflammation and barrier dysfunction
Q28391092Heme oxygenase-1 protects corexit 9500A-induced respiratory epithelial injury across species
Q56911131Hepatitis C virus entry into the hepatocyte
Q84434171Hepatocyte growth factor stimulates the migration of gastric epithelial cells by altering the subcellular localization of the tight junction protein ZO-1
Q28569839Hepatocyte nuclear factor (HNF)-4α triggers formation of functional tight junctions and establishment of polarized epithelial morphology in F9 embryonal carcinoma cells
Q38695885Histone deacetylase inhibition prevents cell death induced by loss of tricellular tight junction proteins in temperature-sensitive mouse cochlear cells
Q33965984Holey barrier: claudins and the regulation of brain endothelial permeability
Q63740474Human Vascular Pericytes and Cytomegalovirus Pathobiology
Q33346003Human hereditary hearing impairment: mouse models can help to solve the puzzle
Q36114911Human intestinal epithelial cell line SK-CO15 is a new model system to study Na(+)/H(+) exchanger 3
Q51978709Human salivary gland branching morphogenesis: morphological localization of claudins and its parallel relation with developmental stages revealed by expression of cytoskeleton and secretion markers.
Q49202522Human small intestine is capable of restoring barrier function after short ischemic periods
Q42474949Hyperosmolarity-Induced Down-Regulation of Claudin-2 Mediated by Decrease in PKCβ-Dependent GATA-2 in MDCK Cells
Q41914153Hypotonic Stress-induced Down-regulation of Claudin-1 and -2 Mediated by Dephosphorylation and Clathrin-dependent Endocytosis in Renal Tubular Epithelial Cells
Q40153022Hypoxia disrupts the barrier function of neural blood vessels through changes in the expression of claudin-5 in endothelial cells
Q91803027Hypoxic Environment Promotes Barrier Formation in Human Intestinal Epithelial Cells through Regulation of MicroRNA 320a Expression
Q37217121IGF-I regulates tight-junction protein claudin-1 during differentiation of osteoblast-like MC3T3-E1 cells via a MAP-kinase pathway
Q45046111IL-1beta regulates expression of Cx32, occludin, and claudin-2 of rat hepatocytes via distinct signal transduction pathways
Q45233841ILDR1 is important for paracellular water transport and urine concentration mechanism.
Q42814410Identification and characterization of JRAB/MICAL-L2, a junctional Rab13-binding protein
Q38930038Identification and chromosomal localization of one locus of Leishmania (L.) major related with resistance to itraconazole
Q42513671Identification and subcellular localization of paracellin-1 (claudin-16) in human salivary glands
Q24293163Identification of MarvelD3 as a tight junction-associated transmembrane protein of the occludin family
Q36324231Identification of a tight junction-associated guanine nucleotide exchange factor that activates Rho and regulates paracellular permeability
Q33317834Identification of adherens junction-associated GTPase activating proteins by the fluorescence localization-based expression cloning.
Q35539472Identification of novel immune and barrier genes in atopic dermatitis by means of laser capture microdissection.
Q85039312Immunohistochemical analysis of colorectal cancer with gastric phenotype: Claudin-18 is associated with poor prognosis
Q42590043Immunohistochemical profiles of claudin-3 in primary and metastatic prostatic adenocarcinoma.
Q35082674Immunohistological characterization of intercellular junction proteins in rhesus macaque intestine
Q47280497Immunolocalization of tight junction proteins in the adult and developing human brain
Q89338409Immunoreactivity patterns of tight junction proteins are useful for differential diagnosis of human salivary gland tumors
Q42042176Immunosuppressant MPA Modulates Tight Junction through Epigenetic Activation of MLCK/MLC-2 Pathway via p38MAPK.
Q89522263Impact of a high‑fat diet on intestinal stem cells and epithelial barrier function in middle‑aged female mice
Q39388126Impact of mycotoxins on the intestine: are mucus and microbiota new targets?
Q36121354Impaired Tight Junctions in Atopic Dermatitis Skin and in a Skin-Equivalent Model Treated with Interleukin-17.
Q64982692Implications of AMPK in the Formation of Epithelial Tight Junctions.
Q24306339Implications of nectin-like molecule-2/IGSF4/RA175/SgIGSF/TSLC1/SynCAM1 in cell-cell adhesion and transmembrane protein localization in epithelial cells
Q37781315Importance of disrupted intestinal barrier in inflammatory bowel diseases
Q58250615In Vitro Screening of Blood-Brain Barrier Penetration of Monoquaternary Acetylcholinesterase Reactivators
Q38749332In vivo measurement of vocal fold surface resistance
Q39789847Inducible Expression of Claudin-1 in Glomerular Podocytes Generates Aberrant Tight Junctions and Proteinuria through Slit Diaphragm Destabilization
Q36146446Infection and upregulation of proinflammatory cytokines in human brain vascular pericytes by human cytomegalovirus
Q38902578Inflammation and the Intestinal Barrier: Leukocyte-Epithelial Cell Interactions, Cell Junction Remodeling, and Mucosal Repair
Q36631468Inflammatory bowel disease and the apical junctional complex
Q44800688Inflammatory mediators weaken the amniotic membrane barrier through disruption of tight junctions
Q38763824Influence of Enamel Matrix Derivative on Human Epithelial Cells In Vitro
Q40809595Influence of retinoic acid on human gingival epithelial barriers
Q34426899Inhibition of Src phosphorylation reduces damage to the blood-brain barrier following transient focal cerebral ischemia in rats
Q39824870Inhibition of basal p38 or JNK activity enhances epithelial barrier function through differential modulation of claudin expression
Q40958947Inhibition of histone deacetylase 6 restores intestinal tight junction in hemorrhagic shock
Q40682472Inhibitors of glycosphingolipid biosynthesis reduce transepithelial electrical resistance in MDCK I and FRT cells
Q37280601Innate Immunity in the Female Reproductive Tract: Role of Sex Hormones in Regulating Uterine Epithelial Cell Protection Against Pathogens
Q92301873Inner Blood-Retinal Barrier Regulation in Retinopathies
Q90705746Integrated genomic and methylation profile analysis to identify candidate tumor marker genes in patients with colorectal cancer
Q54568836Integrity and barrier function of the epidermis critically depend on glucosylceramide synthesis.
Q39269431Interactions of Giardia sp. with the intestinal barrier: Epithelium, mucus, and microbiota
Q34360639Intercellular junctions and cellular polarity: the PAR-aPKC complex, a conserved core cassette playing fundamental roles in cell polarity.
Q53153713Interferon-gamma increased epithelial barrier function via upregulating claudin-7 expression in human submandibular gland duct epithelium.
Q40790831Interleukin-2 receptor beta subunit-dependent and -independent regulation of intestinal epithelial tight junctions
Q89886066Intestinal Barrier Dysfunction, LPS Translocation, and Disease Development
Q40272327Intestinal Transport Characteristics and Metabolism of C-Glucosyl Dihydrochalcone, Aspalathin
Q28250081Intestinal barrier function: molecular regulation and disease pathogenesis
Q50600432Intestinal deletion of Claudin-7 enhances paracellular organic solute flux and initiates colonic inflammation in mice.
Q39298268Intestinal epithelial claudins: expression and regulation in homeostasis and inflammation
Q47104884Intestinal epithelium, intraepithelial lymphocytes and the gut microbiota - Key players in the pathogenesis of celiac disease.
Q26859272Intestinal permeability regulation by tight junction: implication on inflammatory bowel diseases
Q27015884Intestinal permeability--a new target for disease prevention and therapy
Q90604164Intestine-specific expression of human chimeric intestinal alkaline phosphatase attenuates Western diet-induced barrier dysfunction and glucose intolerance
Q42822156Intracellular Haemophilus influenzae invades the brain: is zyxin a critical blood brain barrier component regulated by TNF-α?
Q40077004Involvement of Rab13 and JRAB/MICAL-L2 in epithelial cell scattering.
Q24309562Involvement of actinin-4 in the recruitment of JRAB/MICAL-L2 to cell-cell junctions and the formation of functional tight junctions
Q36523471Involvement of cell junctions in hepatocyte culture functionality
Q41741480Involvement of intracellular signaling in the IL-1β inhibitory effect on fructose intestinal absorption
Q30157022Involvement of the interaction of afadin with ZO-1 in the formation of tight junctions in Madin-Darby canine kidney cells
Q36066313Ion dependence of Na-K-ATPase-mediated epithelial cell adhesion and migration
Q41503343Irsogladine maleate regulates gap junctional intercellular communication-dependent epithelial barrier in human nasal epithelial cells
Q28591650JACOP, a novel plaque protein localizing at the apical junctional complex with sequence similarity to cingulin
Q41847742JAM-A and aPKC: A close pair during cell-cell contact maturation and tight junction formation in epithelial cells.
Q36294373JAM-A regulates permeability and inflammation in the intestine in vivo
Q28588755JAM-C regulates tight junctions and integrin-mediated cell adhesion and migration
Q38199343JAM-related proteins in mucosal homeostasis and inflammation
Q28506613JAM4, a junctional cell adhesion molecule interacting with a tight junction protein, MAGI-1
Q28208782JEAP, a novel component of tight junctions in exocrine cells
Q24306920JRAB/MICAL-L2 is a junctional Rab13-binding protein mediating the endocytic recycling of occludin
Q37952877Jumping the barrier: VE-cadherin, VEGF and other angiogenic modifiers in cancer.
Q47771280Junctional Adhesion Molecules (JAMs): Cell Adhesion Receptors With Pleiotropic Functions in Cell Physiology and Development.
Q24669667Junctional adhesion molecule (JAM) binds to PAR-3: a possible mechanism for the recruitment of PAR-3 to tight junctions
Q42085912Junctional adhesion molecule-A is required for hematogenous dissemination of reovirus
Q40241931Junctional adhesion molecule-a participates in the formation of apico-basal polarity through different domains
Q54277662Junctional adhesion molecules 2 and 3 may potentially be involved in progression of gastric adenocarcinoma tumors.
Q79079253Junctional complex revisited by high‐resolution scanning electron microscopy
Q35046911Junctional complexes of the blood-brain barrier: permeability changes in neuroinflammation
Q30384261Junctional music that the nucleus hears: cell-cell contact signaling and the modulation of gene activity.
Q41849877Keratinocyte junctions and the epidermal barrier: how to make a skin-tight dress
Q45249905Knockdown of occludin expression leads to diverse phenotypic alterations in epithelial cells.
Q39904783Knockdown of tight junction protein claudin-2 prevents bile canalicular formation in WIF-B9 cells
Q34103720Knockout mice reveal key roles for claudin 18 in alveolar barrier properties and fluid homeostasis
Q35810069Label-free analysis of breast tissue polarity by Raman imaging of lipid phase
Q35150607Lactobacillus reuteri I5007 modulates tight junction protein expression in IPEC-J2 cells with LPS stimulation and in newborn piglets under normal conditions
Q39434367Layered defense: how mucus and tight junctions seal the intestinal barrier
Q38002767Lecture: New light on the role of claudins in the kidney
Q54592882Ligand-of-Numb protein X is an endocytic scaffold for junctional adhesion molecule 4.
Q35841899Lipid polarity is maintained in absence of tight junctions
Q37777780Looking at the blood–brain barrier: Molecular anatomy and possible investigation approaches
Q48357621Loss and recovery of the blood-nerve barrier in the rat sciatic nerve after crush injury are associated with expression of intercellular junctional proteins
Q84779796Loss of Claudin-15, but Not Claudin-2, Causes Na+ Deficiency and Glucose Malabsorption in Mouse Small Intestine
Q38859765Loss of Desmoglein 2 Contributes to the Pathogenesis of Crohn's Disease
Q39943968Loss of occludin affects tricellular localization of tricellulin.
Q41846918Loss of tight junction proteins (Claudin 1, 4, and 7) correlates with aggressive behavior in colorectal carcinoma
Q92839247Low expression of occludin: a predictor of poor prognosis in esophageal squamous cell carcinoma
Q36513217Luminal B tumors are the most frequent molecular subtype in breast cancer of North African women: an immunohistochemical profile study from Morocco
Q45189883Luminal cysteine-proteases degrade colonic tight junction structure and are responsible for abdominal pain in constipation-predominant IBS.
Q47413203Lysophosphatidic Acid Receptor 1 Is Important for Intestinal Epithelial Barrier Function and Susceptibility to Colitis
Q35018207Lysophosphatidic acid in vascular development and disease
Q58769609M cell-dependent antigen uptake on follicle-associated epithelium for mucosal immune surveillance
Q40368399MA026, an anti-hepatitis C virus compound, opens tight junctions of the epithelial cell membrane.
Q46697366MAGI-1 is a component of the glomerular slit diaphragm that is tightly associated with nephrin
Q35018010MARVEL: a conserved domain involved in membrane apposition events
Q34517760MCRS1 overexpression, which is specifically inhibited by miR-129*, promotes the epithelial-mesenchymal transition and metastasis in non-small cell lung cancer
Q38685179MPA Modulates Tight Junctions' Permeability via Midkine/PI3K Pathway in Caco-2 Cells: A Possible Mechanism of Leak-Flux Diarrhea in Organ Transplanted Patients
Q37565430MT2-MMP induces proteolysis and leads to EMT in carcinomas
Q38391951Malignant transformation of hyperplastic gastric polyps: An immunohistochemical and pathological study of the changes of neoplastic phenotype
Q91232756Marked Changes in Blood-Brain Barrier Biomarkers After Direct Bypass Surgery for Moyamoya Angiopathy: Preliminary Study
Q35146757Mast cells disrupt epithelial barrier function during enteric nematode infection
Q41598370Maternal obesity in mice not only affects fresh embryo quality but also aggravates injury due to vitrification
Q39120017Mathematical classification of tight junction protein images
Q51640421Matrix metalloproteinase-9-deficient dendritic cells have impaired migration through tracheal epithelial tight junctions.
Q48468454Matrix metalloproteinase-mediated disruption of tight junction proteins in cerebral vessels is reversed by synthetic matrix metalloproteinase inhibitor in focal ischemia in rat.
Q34049874Mechanism of IFN-gamma-induced endocytosis of tight junction proteins: myosin II-dependent vacuolarization of the apical plasma membrane
Q37921172Mechanism of action of 1,25-dihydroxyvitamin D3 on intestinal calcium absorption
Q64448505Mechanisms of Blood Brain Barrier Disruption by Different Types of Bacteria, and Bacterial-Host Interactions Facilitate the Bacterial Pathogen Invading the Brain
Q36166123Mechanisms of the blood-brain barrier disruption in HIV-1 infection
Q54558035Medullary thymic epithelial cells expressing Aire represent a unique lineage derived from cells expressing claudin.
Q38810883Medullary thymic epithelial stem cells: role in thymic epithelial cell maintenance and thymic involution
Q30444715Metastasis suppressor proteins: discovery, molecular mechanisms, and clinical application
Q57374799Methyl-β-Cyclodextrin Increases Permeability of Caco-2 Cell Monolayers by Displacing Specific Claudins from Cholesterol Rich Domains Associated with Tight Junctions
Q37047074MicroRNA regulation of intestinal epithelial tight junction permeability
Q38696037MicroRNA-210 Suppresses Junction Proteins and Disrupts Blood-Brain Barrier Integrity in Neonatal Rat Hypoxic-Ischemic Brain Injury.
Q35109715Microbial pathogenesis and cytoskeletal function.
Q39363389Microbiome and NAFLD: potential influence of aerobic fitness and lifestyle modification
Q42558418Microtubule disassembly breaks down the barrier integrity of corneal endothelium
Q30809823Microtubules regulate disassembly of epithelial apical junctions
Q35295818Migration of Toxoplasma gondii across biological barriers
Q37982360Modulation of tight junction structure and function by kinases and phosphatases targeting occludin
Q48253457Molecular and Physiological Effects on the Small Intestine of Weaner Pigs Following Feeding with Deoxynivalenol-Contaminated Feed
Q35919870Molecular and cellular mechanisms of tight junction dysfunction in the irritable bowel syndrome
Q77110276Molecular and cellular permeability control at the blood-brain barrier
Q47069445Molecular and functional analysis of apical junction formation in the gut epithelium of Caenorhabditis elegans
Q28510848Molecular characterization of angiomotin/JEAP family proteins: interaction with MUPP1/Patj and their endogenous properties
Q36032680Molecular genetics of MARVELD2 and clinical phenotype in Pakistani and Slovak families segregating DFNB49 hearing loss
Q35586708Molecular networks controlling epithelial cell polarity in development
Q37810004Morphology and Properties of Brain Endothelial Cells
Q73396773Morphology and physiology of the blood-brain barrier
Q28203316Multi-PDZ domain protein 1 (MUPP1) is concentrated at tight junctions through its possible interaction with claudin-1 and junctional adhesion molecule
Q34110996Multiple facets of intestinal permeability and epithelial handling of dietary antigens
Q33734527Multiple protein interactions involving proposed extracellular loop domains of the tight junction protein occludin
Q40434620Muscarinic acetylcholine receptor-mediated tight junction opening is involved in epiphora in late phase of submandibular gland transplantation
Q34731236Myeloperoxidase-derived oxidants induce blood-brain barrier dysfunction in vitro and in vivo
Q91811265N-acetylcysteine Amide Ameliorates Blast-Induced Changes in Blood-Brain Barrier Integrity in Rats
Q89880370N-acetylcysteine decreases airway inflammation and responsiveness in asthma by modulating claudin 18 expression
Q35973447NG2, a common denominator for neuroinflammation, blood-brain barrier alteration, and oligodendrocyte precursor response in EAE, plays a role in dendritic cell activation
Q39850572NHS-A isoform of the NHS gene is a novel interactor of ZO-1.
Q26779447Nanoparticle based insulin delivery system: the next generation efficient therapy for Type 1 diabetes
Q59806591Necrotizing enterocolitis leads to disruption of tight junctions and increase in gut permeability in a mouse model
Q39083230Nectin and junctional adhesion molecule are critical cell adhesion molecules for the apico-basal alignment of adherens and tight junctions in epithelial cells.
Q53093542Nectin-3 Is Increased in the Cell Junctions of the Uterine Epithelium at Implantation.
Q34220056Nectins and nectin-like molecules: roles in cell adhesion, migration, and polarization.
Q42917125Neuroglian, Gliotactin, and the Na+/K+ ATPase are essential for septate junction function in Drosophila
Q33643866Neurovascular unit on a chip: implications for translational applications.
Q37791921New aspects of the molecular constituents of tissue barriers
Q37360580New diagnostic and molecular characteristics of malignant mesothelioma
Q35548957Nitric Oxide/Nitric Oxide Synthase, Spermatogenesis, and Tight Junction Dynamics1
Q42082089No static at all.
Q39332710Non-canonical functions of claudin proteins: Beyond the regulation of cell-cell adhesions
Q28508837Normal establishment of epithelial tight junctions in mice and cultured cells lacking expression of ZO-3, a tight-junction MAGUK protein
Q39280432Novel roles of Vmp1: inhibition metastasis and proliferation of hepatocellular carcinoma
Q33812424Nuclear accumulation of symplekin promotes cellular proliferation and dedifferentiation in an ERK1/2-dependent manner
Q47145929Nuclear expression of claudin-3 in human colorectal adenocarcinoma cell lines and tissues
Q41117734Nuclear localization of tricellulin promotes the oncogenic property of pancreatic cancer
Q52648199Occludin induces microvillus formation via phosphorylation of ezrin in a mouse hepatic cell line.
Q40141217Occludin-mediated premature senescence is a fail-safe mechanism against tumorigenesis in breast carcinoma cells
Q40145744Oncostatin M induces upregulation of claudin-2 in rodent hepatocytes coinciding with changes in morphology and function of tight junctions
Q64265564Oral Mucosal Epithelial Cells
Q52723966Organic osmolytes preserve the function of the developing tight junction in ultraviolet B-irradiated rat epidermal keratinocytes.
Q37118549Organization of multiprotein complexes at cell-cell junctions
Q42443965Overexpression of the calcium sensing receptor accelerates epidermal differentiation and permeability barrier formation in vivo
Q37835839Oxidative stress and blood-brain barrier dysfunction under particular consideration of matrix metalloproteinases.
Q35650728PALS1 regulates E-cadherin trafficking in mammalian epithelial cells
Q35632826PATJ regulates directional migration of mammalian epithelial cells
Q36321518PATJ regulates tight junction formation and polarity in mammalian epithelial cells
Q30164767PDZ Domain Proteins: Plug and Play!
Q37571326Paracellular Cl- permeability is regulated by WNK4 kinase: insight into normal physiology and hypertension
Q28279500Paracellular drug absorption enhancement through tight junction modulation
Q37727943Partial recovery of the damaged rat blood-brain barrier is mediated by adherens junction complexes, extracellular matrix remodeling and macrophage infiltration following focal astrocyte loss
Q38936511Pathobiology of neutrophil-epithelial interactions
Q37592281Pathogen translocation across the blood-brain barrier
Q40084707Pathophysiological role of the activation of p38 mitogen-activated protein kinases in poorly differentiated gastric cancer
Q50450544Perfluorooctanoic acid disrupts the blood-testis barrier and activates the TNFα/p38 MAPK signaling pathway in vivo and in vitro.
Q28577856Peripheral myelin protein 22 is a constituent of intercellular junctions in epithelia
Q28265568Pertussis toxin transiently affects barrier integrity, organelle organization and transmigration of monocytes in a human brain microvascular endothelial cell barrier model
Q97643659Phase separation as a therapeutic target in tight junction-associated human diseases
Q33758290Phenotypic and genetic aspects of epithelial barrier function in asthmatic patients
Q93132997Phosphorylated claudin-16 interacts with Trpv5 and regulates transcellular calcium transport in the kidney
Q24302552Phosphorylation of claudin-3 at threonine 192 by cAMP-dependent protein kinase regulates tight junction barrier function in ovarian cancer cells
Q34116905Phosphorylation of ephrin-B1 via the interaction with claudin following cell-cell contact formation
Q37508192Phylogeny of proteolipid proteins: divergence, constraints, and the evolution of novel functions in myelination and neuroprotection
Q24291796Pilt, a novel peripheral membrane protein at tight junctions in epithelial cells
Q54266973Pirfenidone exhibits cardioprotective effects by regulating myocardial fibrosis and vascular permeability in pressure-overloaded hearts.
Q40134757Pituitary Adenylate Cyclase Activating Polypeptide, A Potential Therapeutic Agent for Diabetic Retinopathy in Rats: Focus on the Vertical Information Processing Pathway
Q46498130Platelet adhesion in hypertension: application of a novel assay of platelet adhesion
Q34301265Platelets potentiate brain endothelial alterations induced by Plasmodium falciparum
Q24795727Polarity determination in breast tissue: desmosomal adhesion, myoepithelial cells, and laminin 1
Q33966512Polarity protein complex Scribble/Lgl/Dlg and epithelial cell barriers
Q36530065Polarization and myelination in myelinating glia
Q42864321Poly(I:C) reduces expression of JAM-A and induces secretion of IL-8 and TNF-α via distinct NF-κB pathways in human nasal epithelial cells
Q92259550Polyhexamethylene Guanidine Phosphate Damages Tight Junctions and the F-Actin Architecture by Activating Calpain-1 via the P2RX7/Ca2+ Signaling Pathway
Q36808308Polymeric nanoparticle drug delivery technologies for oral delivery applications
Q37167611Pores in the epidermis: aquaporins and tight junctions
Q37480371Possible angiogenic roles for claudin-4 in ovarian cancer
Q37967680Possible involvement of tight junctions, extracellular matrix and nuclear receptors in epithelial differentiation
Q34439240Potential markers that complement expression of CA125 in epithelial ovarian cancer
Q37248478Potentiometric-scanning ion conductance microscopy for measurement at tight junctions
Q28513418Predicted expansion of the claudin multigene family
Q47670930Primary angle closure glaucoma (PACG) susceptibility gene PLEKHA7 encodes a novel Rac1/Cdc42 GAP that modulates cell migration and blood-aqueous barrier function
Q92493716Principles and Applications of Biological Membrane Organization
Q36749403Pro-inflammatory miR-223 mediates the cross-talk between the IL23 pathway and the intestinal barrier in inflammatory bowel disease
Q58186380Probing effects of pH change on dynamic response of Claudin-2 mediated adhesion using single molecule force spectroscopy
Q60515769Probiotic Species Strengthen Intestinal Barrier Function and Tight Junction Integrity in Experimental Necrotizing Enterocolitis
Q47584454Process of tight junction recovery in the injured vocal fold epithelium: Morphological and paracellular permeability analysis.
Q35673622Prognostic and clinical significance of claudin-4 in gastric cancer: a meta-analysis
Q48008368Prognostic significance of the genetic and the immunohistochemical expression of epithelial-mesenchymal-related markers in colon cancer
Q36815936Progress in absorption enhancers based on tight junction
Q28568696Proinflammatory cytokines tumor necrosis factor-alpha and interferon-gamma alter tight junction structure and function in the rat parotid gland Par-C10 cell line
Q34187574Prostaglandin-induced cervical remodelling in humans in the first trimester is associated with increased expression of specific tight junction, but not gap junction proteins
Q35928397Protective Effects of Ferulic Acid against Heat Stress-Induced Intestinal Epithelial Barrier Dysfunction In Vitro and In Vivo
Q64943693Protective Effects of a Lipid Extract from Hard-Shelled Mussel (Mytilus coruscus) on Intestinal Integrity after Lipopolysaccharide Challenge in Mice.
Q33440901Protein kinase C activation disrupts epithelial apical junctions via ROCK-II dependent stimulation of actomyosin contractility
Q34081941Protein kinase C activation has distinct effects on the localization, phosphorylation and detergent solubility of the claudin protein family in tight and leaky epithelial cells
Q39429708Protein kinase Cα inhibitor enhances the sensitivity of human pancreatic cancer HPAC cells to Clostridium perfringens enterotoxin via claudin-4.
Q35976653Protein kinase cβ phosphorylates occludin regulating tight junction trafficking in vascular endothelial growth factor-induced permeability in vivo
Q45294292Protein profile of the luteal phase endometrium by tissue microarray assessment
Q37746454Protein subcellular localization in bacteria
Q38266101Proteins and peptides: The need to improve them as promising therapeutics for ulcerative colitis.
Q37576326Proteome changes in the small intestinal mucosa of growing pigs with dietary supplementation of non-starch polysaccharide enzymes
Q28544676Proteomic analysis of proteins surrounding occludin and claudin-4 reveals their proximity to signaling and trafficking networks
Q41982297Pseudomonas aeruginosa elastase causes transient disruption of tight junctions and downregulation of PAR-2 in human nasal epithelial cells
Q37095009Puerarin transport across a Calu-3 cell monolayer - an in vitro model of nasal mucosa permeability and the influence of paeoniflorin and menthol
Q41503540Puerarin transport across rat nasal epithelial cells and the influence of compatibility with peoniflorin and menthol
Q28207789Putting tumours in context
Q38932562Pyrrolidine dithiocarbamate restores gastric damages and suppressive autophagy induced by hydrogen peroxide.
Q92785707R40.76 binds to the α domain of ZO-1: role of ZO-1 (α+) in epithelial differentiation and mechano-sensing
Q24311646Rab13 mediates the continuous endocytic recycling of occludin to the cell surface
Q24337319Rab13 regulates PKA signaling during tight junction assembly
Q30529893Rab13 small G protein and junctional Rab13-binding protein (JRAB) orchestrate actin cytoskeletal organization during epithelial junctional development
Q36161700Rab27 effector Slp2-a transports the apical signaling molecule podocalyxin to the apical surface of MDCK II cells and regulates claudin-2 expression.
Q91645103Reciprocal Association between the Apical Junctional Complex and AMPK: A Promising Therapeutic Target for Epithelial/Endothelial Barrier Function?
Q34873529Recombinant human sonic hedgehog protein regulates the expression of ZO-1 and occludin by activating angiopoietin-1 in stroke damage
Q38978743Redox-sensitive structure and function of the first extracellular loop of the cell-cell contact protein claudin-1: lessons from molecular structure to animals
Q40429873Regulation of E-cadherin endocytosis by nectin through afadin, Rap1, and p120ctn
Q91994983Regulation of Epithelial Cell Functions by the Osmolality and Hydrostatic Pressure Gradients: A Possible Role of the Tight Junction as a Sensor
Q24548016Regulation of PCNA and cyclin D1 expression and epithelial morphogenesis by the ZO-1-regulated transcription factor ZONAB/DbpA
Q34061031Regulation of airway tight junctions by proinflammatory cytokines
Q33863571Regulation of blood-testis barrier (BTB) dynamics during spermatogenesis via the "Yin" and "Yang" effects of mammalian target of rapamycin complex 1 (mTORC1) and mTORC2.
Q47354964Regulation of blood-testis barrier assembly in vivo by germ cells
Q38199105Regulation of claudins in blood-tissue barriers under physiological and pathological states
Q34858216Regulation of endothelial cell contacts during leukocyte extravasation
Q35846716Regulation of epithelial permeability by the actin cytoskeleton
Q34287155Regulation of intestinal epithelial permeability by tight junctions.
Q40624224Regulation of intestinal homeostasis by the ulcerative colitis-associated gene RNF186.
Q39454371Regulation of intrahepatic biliary duct morphogenesis by Claudin 15-like b.
Q37687731Regulation of ionotropic glutamate receptors by their auxiliary subunits
Q35153994Regulation of mucosal immunity in the female reproductive tract: the role of sex hormones in immune protection against sexually transmitted pathogens
Q39906454Regulation of renal epithelial tight junctions by the von Hippel-Lindau tumor suppressor gene involves occludin and claudin 1 and is independent of E-cadherin
Q28204178Regulation of the Expression of the Prostate-specific Antigen by Claudin-7
Q40338912Regulation of the assembly and adhesion activity of E-cadherin by nectin and afadin for the formation of adherens junctions in Madin-Darby canine kidney cells
Q33306608Regulation of tight junction assembly and epithelial morphogenesis by the heat shock protein Apg-2
Q39336324Regulation of tight junctions in human normal pancreatic duct epithelial cells and cancer cells
Q38091094Regulation of tight junctions in upper airway epithelium
Q36450027Regulation of transport in the connecting tubule and cortical collecting duct
Q27027456Regulatory pathways affecting vascular stabilization via VE-cadherin dynamics: insights from zebrafish (Danio rerio)
Q53650326Relative contribution of cell contact pattern, specific PKC isoforms and gap junctional communication in tight junction assembly in the mouse early embryo.
Q59795352Replacement of grains with soybean hulls ameliorates SARA-induced impairment of the colonic epithelium barrier function of goats
Q39734201Requirement of ZO-1 for the formation of belt-like adherens junctions during epithelial cell polarization
Q40293957Requirement of nectin, but not cadherin, for formation of claudin-based tight junctions in annexin II-knockdown MDCK cells
Q40522184Requirement of the actin cytoskeleton for the association of nectins with other cell adhesion molecules at adherens and tight junctions in MDCK cells.
Q91622767Rescue of tight junctional localization of a claudin-16 mutant D97S by antimalarial medicine primaquine in Madin-Darby canine kidney cells
Q50713401Resealing of endothelial junctions by focal adhesion kinase.
Q64068590Resveratrol inhibits paclitaxel-induced neuropathic pain by the activation of PI3K/Akt and SIRT1/PGC1α pathway
Q45028397Reversible disruption of tight junction complexes in the rat blood-brain barrier, following transitory focal astrocyte loss
Q37800133Review: Molecular pathogenesis of blood–brain barrier breakdown in acute brain injury
Q24548276Rhamnolipids are virulence factors that promote early infiltration of primary human airway epithelia by Pseudomonas aeruginosa
Q36056399Rho GTP exchange factor ARHGEF11 regulates the integrity of epithelial junctions by connecting ZO-1 and RhoA-myosin II signaling
Q35949016Rho/Rho-associated kinase-II signaling mediates disassembly of epithelial apical junctions
Q34359173Role for actin filament turnover and a myosin II motor in cytoskeleton-driven disassembly of the epithelial apical junctional complex
Q35142103Role of Estrogen Receptor-α in the Regulation of Claudin-6 Expression in Breast Cancer Cells
Q52573012Role of cell adhesion molecule nectin-3 in spermatid development.
Q34888133Role of claudin species-specific dynamics in reconstitution and remodeling of the zonula occludens
Q35127976Role of interendothelial adhesion molecules in the control of vascular functions
Q47102832Role of matrix metalloproteinase-2/9 (MMP2/9) in lead-induced changes in an in vitro blood-brain barrier model
Q36944609Role of mitochondrial respiratory chain complex III in high glucose peritoneal dialysate-induced hyperpermeability of HPMCs
Q52876379Role of regenerating gene I in claudin expression and barrier function in the small intestine.
Q38594976Role of tight junctions in signal transduction: an update.
Q42441604Roles of gap junctions in glucose transport from glucose transporter 1-positive to -negative cells in the lateral wall of the rat cochlea
Q35954748Roles of nectins in cell adhesion, migration and polarization.
Q39084479Roles of the cytoskeleton, cell adhesion and rho signalling in mechanosensing and mechanotransduction.
Q28572063SUMOylation attenuates sensitivity toward hypoxia- or desferroxamine-induced injury by modulating adaptive responses in salivary epithelial cells
Q44896653Salmonella enterica serovar Typhimurium regulates intercellular junction proteins and facilitates transepithelial neutrophil and bacterial passage
Q36828527Scanning ion conductance microscopy measurement of paracellular channel conductance in tight junctions
Q36483860Segmental Differences in Radiation-Induced Alterations of Tight Junction-Related Proteins in Non-Human Primate Jejunum, Ileum and Colon
Q37295746Sequential biphasic changes in claudin1 and claudin4 expression are correlated to colorectal cancer progression and liver metastasis
Q43884308Serine proteases decrease intestinal epithelial ion permeability by activation of protein kinase Czeta
Q35073616Sertoli cell tight junction dynamics: their regulation during spermatogenesis
Q37334338Sex hormone regulation of innate immunity in the female reproductive tract: the role of epithelial cells in balancing reproductive potential with protection against sexually transmitted pathogens.
Q34180670Signalling to and from tight junctions
Q38796060Signals and Receptors
Q39877904Similar and distinct properties of MUPP1 and Patj, two homologous PDZ domain-containing tight-junction proteins.
Q80532326Simultaneous cell death and desquamation of the embryonic diffusion barrier during epidermal development
Q37308921Simvastatin alleviates hyperpermeability of glomerular endothelial cells in early-stage diabetic nephropathy by inhibition of RhoA/ROCK1.
Q36322348Sinuous is a Drosophila claudin required for septate junction organization and epithelial tube size control
Q28203769Size-selective loosening of the blood-brain barrier in claudin-5-deficient mice
Q35757285Skin barrier disruption: a requirement for allergen sensitization?
Q42815956Small GTPase proteins Rin and Rit Bind to PAR6 GTP-dependently and regulate cell transformation
Q27666896Solution structure of the second PDZ domain of Zonula Occludens 1
Q28504768Sp1 site is crucial for the mouse claudin-19 gene expression in the kidney cells
Q58480697Spatial Overlap of Claudin- and Phosphatidylinositol Phosphate-Binding Sites on the First PDZ Domain of Zonula Occludens 1 Studied by NMR.
Q45089664Spatiotemporal regulation of morphogenetic molecules during in vitro branching of the isolated ureteric bud: toward a model of branching through budding in the developing kidney
Q35534690Spectrin-adducin membrane skeleton: A missing link between epithelial junctions and the actin cytoskeletion?
Q36181772Sphingosine 1-phosphate receptor 5 mediates the immune quiescence of the human brain endothelial barrier
Q51645776Staphylococcus aureus impairs the airway epithelial barrier in vitro.
Q35071400Sticky business: orchestrating cellular signals at adherens junctions
Q113959010Structural Revision of Natural Cyclic Depsipeptide MA026 Established by Total Synthesis and Biosynthetic Gene Cluster Analysis
Q39324341Structural and functional alteration of corneal epithelial barrier under inflammatory conditions
Q50309594Structurally and functionally characterized in vitro model of rabbit vocal fold epithelium
Q38110756Structure and function of the thin limbs of the loop of Henle
Q24321126Structure of a cell polarity regulator, a complex between atypical PKC and Par6 PB1 domains
Q27671708Structure of the Food-Poisoning Clostridium perfringens Enterotoxin Reveals Similarity to the Aerolysin-Like Pore-Forming Toxins
Q40224183Study of claudin function by RNA interference
Q39409518Suppression of Rac1 activity at the apical membrane of MDCK cells is essential for cyst structure maintenance.
Q33664419Symplekin promotes tumorigenicity by up-regulating claudin-2 expression
Q36012269Synapses: sites of cell recognition, adhesion, and functional specification.
Q28271194Systems Proteomics View of the Endogenous Human Claudin Protein Family
Q42917997TGF-beta receptor kinase inhibitor enhances growth and integrity of embryonic stem cell-derived endothelial cells
Q29619820TGF-beta-induced epithelial to mesenchymal transition
Q34145044TGF-β-induced MiR-491-5p Expression Promotes Par-3 Degradation in Rat Proximal Tubular Epithelial Cells
Q49357566TRPA1-dependent reversible opening of tight junction by natural compounds with an α,β-unsaturated moiety and capsaicin
Q42805342TRPV4 Regulates Tight Junctions and Affects Differentiation in a Cell Culture Model of the Corneal Epithelium.
Q34124455Targeted disruption of outer limiting membrane junctional proteins (Crb1 and ZO-1) increases integration of transplanted photoreceptor precursors into the adult wild-type and degenerating retina.
Q34614482Targeted proteasome inhibition by Velcade induces apoptosis in human mesothelioma and breast cancer cell lines
Q37699264Targeted therapy in uterine serous carcinoma: an aggressive variant of endometrial cancer
Q64089708Targeting claudin-4 enhances CDDP-chemosensitivity in gastric cancer
Q89840285Targeting claudin-4 enhances chemosensitivity in breast cancer
Q93194999Targeting claudin-4 enhances chemosensitivity of pancreatic ductal carcinomas
Q38026601Targeting claudin-4 in human pancreatic cancer
Q38242808Targeting tight junctions during epithelial to mesenchymal transition in human pancreatic cancer.
Q39117874TcpC protein from E. coli Nissle improves epithelial barrier function involving PKCζ and ERK1/2 signaling in HT-29/B6 cells
Q92286639Testosterone Reduces Tight Junction Complexity and Down-regulates Expression of Claudin-4 and Occludin in the Endometrium in Ovariectomized, Sex-steroid Replacement Rats
Q47069345The C. elegans ezrin-radixin-moesin protein ERM-1 is necessary for apical junction remodelling and tubulogenesis in the intestine
Q41231334The Clinical Signification of Claudin-11 Promoter Hypermethylation for Laryngeal Squamous Cell Carcinoma.
Q36856740The Drosophila tricellular junction protein Gliotactin regulates its own mRNA levels through BMP-mediated induction of miR-184.
Q57950142The Effect of Capsaicin Derivatives on Tight-Junction Integrity and Permeability of Madin-Darby Canine Kidney Cells
Q26747031The Effect of Capsaicin on Salivary Gland Dysfunction
Q59356038The Good, the Bad, and the Shocking: The Multiple Roles of Dengue Virus Nonstructural Protein 1 in Protection and Pathogenesis
Q89743976The IL1β-HER2-CLDN18/CLDN4 axis mediates lung barrier damage in ARDS
Q89552148The Integral Role of Tight Junction Proteins in the Repair of Injured Intestinal Epithelium
Q48300181The NMDA and AMPA/KA receptors are involved in glutamate-induced alterations of occludin expression and phosphorylation in brain endothelial cells
Q49484389The Pulmonary Vascular Barrier: Insights into Structure, Function, and Regulatory Mechanisms
Q50940221The RING finger- and PDZ domain-containing protein PDZRN3 controls localization of the Mg2+ regulator claudin-16 in renal tube epithelial cells.
Q30443412The Rac activator Tiam1 controls tight junction biogenesis in keratinocytes through binding to and activation of the Par polarity complex
Q54636790The Rac1/JNK pathway is critical for EGFR-dependent barrier formation in human airway epithelial cells
Q38267149The Role of the Clathrin Adaptor AP-1: Polarized Sorting and Beyond.
Q39042481The Wnt/planar cell polarity signaling pathway contributes to the integrity of tight junctions in brain endothelial cells
Q36322940The ZO-1-associated Y-box factor ZONAB regulates epithelial cell proliferation and cell density
Q47068943The apical disposition of the Caenorhabditis elegans intestinal terminal web is maintained by LET-413.
Q33619070The apical junctional complex in respiratory diseases
Q24595075The association of microtubules with tight junctions is promoted by cingulin phosphorylation by AMPK.
Q94493870The bicistronic gene würmchen encodes two essential components for epithelial development in Drosophila
Q35909425The blood-brain barrier is disrupted in a mouse model of infantile neuronal ceroid lipofuscinosis: amelioration by resveratrol
Q38134725The blood-brain barrier: an engineering perspective.
Q41966646The cell adhesion molecules Echinoid and Friend of Echinoid coordinate cell adhesion and cell signaling to regulate the fidelity of ommatidial rotation in the Drosophila eye
Q30805771The cell junction protein VAB-9 regulates adhesion and epidermal morphology in C. elegans
Q37302556The claudin family of proteins in human malignancy: a clinical perspective
Q47072676The claudin-like megatrachea is essential in septate junctions for the epithelial barrier function in Drosophila.
Q37350823The claudins
Q24675378The conditional inactivation of the beta-catenin gene in endothelial cells causes a defective vascular pattern and increased vascular fragility
Q35067772The development of nasal polyp disease involves early nasal mucosal inflammation and remodelling
Q37813173The diagnostic and molecular characteristics of malignant mesothelioma and ovarian/peritoneal serous carcinoma
Q89982470The differential response of the chicken trachea to chronic infection with virulent Mycoplasma gallisepticum strain Ap3AS and Vaxsafe MG (strain ts-304) - a transcriptional profile
Q37708020The dual role of zonula occludens (ZO) proteins
Q48045527The ecological and genetic basis of convergent thick-lipped phenotypes in cichlid fishes
Q40258168The effect of omega- 3 polyunsaturated fatty acids on endothelial tight junction occludin expression in rat aorta during lipopolysaccharide-induced inflammation
Q37798825The enteric nervous system as a regulator of intestinal epithelial barrier function in health and disease
Q44770771The exon 38-containing ARHGEF11 splice isoform is differentially expressed and is required for migration and growth in invasive breast cancer cells
Q34864544The exploitation of differential endocytic pathways in normal and tumor cells in the selective targeting of nanoparticulate chemotherapeutic agents
Q35145246The expression patterns of tight junction protein claudin-1, -3, and -4 in human gastric neoplasms and adjacent non-neoplastic tissues
Q89808100The extracellular domain of angulin-1 and palmitoylation of its cytoplasmic region are required for angulin-1 assembly at tricellular contacts
Q40383479The four-transmembrane protein IP39 of Euglena forms strands by a trimeric unit repeat.
Q34647328The front line of enteric host defense against unwelcome intrusion of harmful microorganisms: mucins, antimicrobial peptides, and microbiota
Q30159960The heat-shock protein Apg-2 binds to the tight junction protein ZO-1 and regulates transcriptional activity of ZONAB.
Q38811256The interaction of Clostridium perfringens enterotoxin with receptor claudins
Q28587668The interaction of JRAB/MICAL-L2 with Rab8 and Rab13 coordinates the assembly of tight junctions and adherens junctions
Q28277155The intestinal barrier as an emerging target in the toxicological assessment of mycotoxins
Q24320149The keratin-binding protein Albatross regulates polarization of epithelial cells
Q64235087The latest progress on miR-374 and its functional implications in physiological and pathological processes
Q33817521The level of claudin-7 is reduced as an early event in colorectal carcinogenesis
Q89763104The multifarious regulation of the apical junctional complex
Q26865809The ocular surface epithelial barrier and other mechanisms of mucosal protection: from allergy to infectious diseases
Q34103481The organization of tight junctions in epithelia: implications for mammary gland biology and breast tumorigenesis
Q33576633The outer limiting membrane (OLM) revisited: clinical implications
Q48002827The prognostic role of claudins in head and neck squamous cell carcinomas
Q89440743The regulation of junctional actin dynamics by cell adhesion receptors
Q27302299The reversible increase in tight junction permeability induced by capsaicin is mediated via cofilin-actin cytoskeletal dynamics and decreased level of occludin
Q82263885The role of EFA6, exchange factor for Arf6, for tight junction assembly, functions, and interaction with the actin cytoskeleton
Q35875599The role of altered cell-cell communication in melanoma progression
Q48938424The role of caveolin-1 in blood-brain barrier disruption induced by focused ultrasound combined with microbubbles
Q38927656The role of claudins in cancer metastasis
Q44031080The role of glutathione in the permeation enhancing effect of thiolated polymers
Q40217811The role of the beta1 subunit of the Na,K-ATPase and its glycosylation in cell-cell adhesion
Q40052094The role of transcriptional factor p63 in regulation of epithelial barrier and ciliogenesis of human nasal epithelial cells
Q37000458The roles of the Na,K-ATPase beta 1 subunit in pump sorting and epithelial integrity
Q45114983The rotavirus surface protein VP8 modulates the gate and fence function of tight junctions in epithelial cells
Q40439617The second loop of occludin is required for suppression of Raf1-induced tumor growth
Q27312380The structural and functional organization of the podocyte filtration slits is regulated by Tjp1/ZO-1
Q35763162The suprabasal layer of corneal epithelial cells represents the major barrier site to the passive movement of small molecules and trafficking leukocytes
Q42519731The targeted overexpression of a Claudin mutant in the epidermis of transgenic mice elicits striking epidermal and hair follicle abnormalities
Q28211466The tight junction protein ZO-2 localizes to the nucleus and interacts with the heterogeneous nuclear ribonucleoprotein scaffold attachment factor-B
Q30538920The tight junction protein claudin-b regulates epithelial permeability and sodium handling in larval zebrafish, Danio rerio
Q36660697The tight junction protein complex undergoes rapid and continuous molecular remodeling at steady state
Q35777543The tight junction: a multifunctional complex
Q80686035The tight junctional protein occludin is found in the uterine epithelium of squamate reptiles
Q40360748The transcription factors Slug and Snail act as repressors of Claudin-1 expression in epithelial cells.
Q30159513The unique-5 and -6 motifs of ZO-1 regulate tight junction strand localization and scaffolding properties
Q38021504The yin and yang of claudin-14 function in human diseases
Q38725364Therapeutic potential of dairy bioactive peptides: A contemporary perspective
Q40512823Thr(207) of claudin-5 is involved in size-selective loosening of the endothelial barrier by cyclic AMP.
Q39815099Thrombin induces rapid disassembly of claudin-5 from the tight junction of endothelial cells
Q54446299Thymic stromal lymphopoietin induces tight junction protein claudin-7 via NF-kappaB in dendritic cells.
Q28073886Tight Junction Disruption Induced by Type 3 Secretion System Effectors Injected by Enteropathogenic and Enterohemorrhagic Escherichia coli
Q36305755Tight Junction Pore and Leak Pathways: A Dynamic Duo
Q38713034Tight Junction Protein Occludin Is a Porcine Epidemic Diarrhea Virus Entry Factor
Q89509897Tight Junction Proteins and the Biology of Hepatobiliary Disease
Q92354281Tight Junctions of the Outer Blood Retina Barrier
Q28505301Tight function zonula occludens-3 regulates cyclin D1-dependent cell proliferation
Q36337194Tight junction biology and kidney dysfunction
Q34629278Tight junction defects in patients with atopic dermatitis.
Q26777540Tight junction disruption: Helicobacter pylori and dysregulation of the gastric mucosal barrier
Q38193357Tight junction dynamics: the role of junctional adhesion molecules (JAMs).
Q45314147Tight junction interactions
Q36812411Tight junction modulation of the blood brain barrier: CNS delivery of small molecules
Q38227863Tight junction physiology of pleural mesothelium
Q52088623Tight junction proteins ZO-1, occludin, and claudins in developing and adult human perineurium.
Q42985802Tight junction proteins claudin-2 and -12 are critical for vitamin D-dependent Ca2+ absorption between enterocytes.
Q50162449Tight junction proteins in gallbladder epithelium: different expression in acute acalculous and calculous cholecystitis
Q36473683Tight junction proteins in the skin
Q37333599Tight junction-based epithelial microenvironment and cell proliferation
Q38077200Tight junction-related human diseases
Q28203688Tight junction-related protein expression and distribution in human corneal epithelium
Q33676584Tight junctional localization of claudin-16 is regulated by syntaxin 8 in renal tubular epithelial cells
Q37139446Tight junctions and the modulation of barrier function in disease
Q38058856Tight junctions at the blood brain barrier: physiological architecture and disease-associated dysregulation
Q51973279Tight junctions containing claudin 4 and 6 are essential for blastocyst formation in preimplantation mouse embryos.
Q28592632Tight junctions in Schwann cells of peripheral myelinated axons: a lesson from claudin-19-deficient mice
Q27012318Tight junctions in human pancreatic duct epithelial cells
Q33674271Tight junctions in salivary epithelium
Q37733955Tight junctions in the testis: new perspectives.
Q24292730Tight junctions of the blood-brain barrier: development, composition and regulation
Q36950607Tight junctions on the move: molecular mechanisms for epithelial barrier regulation
Q27697986Tight junctions. Structural insight into tight junction disassembly by Clostridium perfringens enterotoxin
Q37420725Tight junctions: a barrier to the initiation and progression of breast cancer?
Q36400271Tight junctions: molecular architecture and function
Q50560839Time- and dose-dependent claudin contribution to biological functions: Lessons from claudin-1 in skin.
Q34103375Tissue architecture: the ultimate regulator of breast epithelial function
Q33817720Tissue polarity-dependent control of mammary epithelial homeostasis and cancer development: an epigenetic perspective
Q47073598Tjp3/zo-3 is critical for epidermal barrier function in zebrafish embryos
Q44582154Total parenteral nutrition adversely affects gut barrier function in neonatal piglets
Q92802972Toward a new generation of smart skins
Q38719405Transcription Factor SOX9 Promotes Osteosarcoma Cell Growth by Repressing Claudin-8 Expression
Q40046453Transcriptional activation of the human claudin-18 gene promoter through two AP-1 motifs in PMA-stimulated MKN45 gastric cancer cells
Q34033442Transcriptional control of tight junction proteins via a protein kinase C signal pathway in human telomerase reverse transcriptase-transfected human pancreatic duct epithelial cells
Q39580311Transcriptional regulation of claudin-18 via specific protein kinase C signaling pathways and modification of DNA methylation in human pancreatic cancer cells
Q28261649Transcriptional regulators of claudins in epithelial tight junctions
Q36546133Transcriptional response of ex vivo human skin to ionizing radiation: comparison between low- and high-dose effects.
Q34328845Transcriptome analysis of the Octopus vulgaris central nervous system
Q58698775Transcriptomic analysis reveal an efficient osmoregulatory system in Siberian sturgeon Acipenser baeri in response to salinity stress
Q39899962Transport and uptake effects of marine complex lipid liposomes in small intestinal epithelial cell models.
Q24679401Tricellulin constitutes a novel barrier at tricellular contacts of epithelial cells
Q28511757Tricellulin deficiency affects tight junction architecture and cochlear hair cells.
Q39224297Tricellulin expression in brain endothelial and neural cells
Q40025036Tricellulin expression in normal and neoplastic human pancreas
Q30491701Tricellulin forms a barrier to macromolecules in tricellular tight junctions without affecting ion permeability
Q39730623Tricellulin forms homomeric and heteromeric tight junctional complexes.
Q28505155Tricellulin is expressed in autotypic tight junctions of peripheral myelinating Schwann cells
Q81326881Trichomonas vaginalis perturbs the junctional complex in epithelial cells
Q33556272Tumor suppressor scribble regulates assembly of tight junctions in the intestinal epithelium
Q33268020Two distinct modes of myosin assembly and dynamics during epithelial wound closure
Q35589987Two sides to every story: the HIF-dependent and HIF-independent functions of pVHL.
Q39785444Two-path impedance spectroscopy for measuring paracellular and transcellular epithelial resistance
Q87822860Type AB thymoma is not a mixed tumor of type A and type B thymomas, but a distinct type of thymoma
Q36969851Type III secretion systems and disease
Q24304509USP9x-mediated deubiquitination of EFA6 regulates de novo tight junction assembly
Q37512902Unexpected roles of the Na-K-ATPase and other ion transporters in cell junctions and tubulogenesis
Q42362918Up-regulation of claudin-2 expression by aldosterone in colonic epithelial cells of mice fed with NaCl-depleted diets.
Q89862050Upregulation of Claudin-7 Expression by Angiotensin II in Colonic Epithelial Cells of Mice Fed with NaCl-Depleted Diets
Q38616313Urinary Claudin-2 Measurements as a Predictor of Necrotizing Enterocolitis: A Pilot Study
Q38130285Uriniferous tubule: structural and functional organization
Q35564741Use of cell-based screening to identify small-molecule compounds that modulate claudin-4 expression
Q34143269Using physiologically-based pharmacokinetic-guided "body-on-a-chip" systems to predict mammalian response to drug and chemical exposure
Q35868623Uterine inactivation of muscle segment homeobox (Msx) genes alters epithelial cell junction proteins during embryo implantation
Q42015867VE-cadherin and claudin-5: it takes two to tango.
Q51062851Value of claudin-4 immunostaining in the diagnosis of mesothelioma.
Q33375197Varicose: a MAGUK required for the maturation and function of Drosophila septate junctions
Q37034906Vascular endothelial growth factor mediates the estrogen-induced breakdown of tight junctions between and increase in proliferation of microvessel endothelial cells in the baboon endometrium
Q38130686Vascular permeability and drug delivery in cancers
Q92533673Vinculin is critical for the robustness of the epithelial cell sheet paracellular barrier for ions
Q36812354Viral interactions with the blood-brain barrier: old dog, new tricks
Q36116932Vitamin D and intestinal calcium absorption
Q33417943Voltage-gated sodium channels in taste bud cells
Q24621479WNK4 regulates apical and basolateral Cl- flux in extrarenal epithelia
Q30746707Water permeability of capillaries in the subfornical organ of rats determined by Gd-DTPA(2-) enhanced 1H magnetic resonance imaging
Q34983471What does irritable bowel syndrome share with non-alcoholic fatty liver disease?
Q39642580Yersinia enterocolitica induces epithelial barrier dysfunction through regional tight junction changes in colonic HT-29/B6 cell monolayers
Q30157199ZO-1 stabilizes the tight junction solute barrier through coupling to the perijunctional cytoskeleton
Q30483283ZO-1- and ZO-2-dependent integration of myosin-2 to epithelial zonula adherens
Q43172469ZO-oming on growth control by junctional proteins.
Q37387966Zona occludens-2 is critical for blood-testis barrier integrity and male fertility
Q28506982Zonula occludens-1 (ZO-1) is involved in morula to blastocyst transformation in the mouse
Q35401854Zonula occludens-1, occludin and E-cadherin expression and organization in salivary glands with Sjögren's syndrome
Q35839775aPKC phosphorylates JAM-A at Ser285 to promote cell contact maturation and tight junction formation
Q33572769alpha-Catenin as a tension transducer that induces adherens junction development
Q38928332c-Jun N-terminal kinase inhibitor SP600125 enhances barrier function and elongation of human pancreatic cancer cell line HPAC in a Ca-switch model
Q39695461c-Jun N-terminal kinase is largely involved in the regulation of tricellular tight junctions via tricellulin in human pancreatic duct epithelial cells
Q38110520miRNA in the regulation of ion channel/transporter expression
Q39125547p38δ mitogen-activated protein kinase regulates the expression of tight junction protein ZO-1 in differentiating human epidermal keratinocytes

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