Genetic polymorphisms in the cyclooxygenase-2 gene, use of nonsteroidal anti-inflammatory drugs, and breast cancer risk

scientific article (publication date: 2006)

Genetic polymorphisms in the cyclooxygenase-2 gene, use of nonsteroidal anti-inflammatory drugs, and breast cancer risk is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1019018138
P356DOI10.1186/BCR1629
P932PMC publication ID1797023
P698PubMed publication ID17181859
P5875ResearchGate publication ID6618191

P50authorAlfred I. NeugutQ107503728
Regina M. SantellaQ113619023
Mary Beth TerryQ75067963
Susan L TeitelbaumQ93243028
Marilie GammonQ104751082
P2093author name stringJing Shen
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Polymorphisms in prostaglandin synthase 2/cyclooxygenase 2 (PTGS2/COX2) and risk of colorectal cancerQ28168820
The role of COX-2 inhibition in breast cancer treatment and preventionQ28168853
Risk of breast cancer among users of aspirin and other anti-inflammatory drugsQ28169157
Nonsteroidal anti-inflammatory drug use and breast cancer risk by stage and hormone receptor statusQ28176257
The proximal region of the 3'-untranslated region of cyclooxygenase-2 is recognized by a multimeric protein complex containing HuR, TIA-1, TIAR, and the heterogeneous nuclear ribonucleoprotein UQ28186564
Nonsteroidal antiinflammatory drugs, cyclooxygenase polymorphisms, and the risk of developing breast carcinoma among women with benign breast diseaseQ28195395
PTGS2 (COX-2) -765G > C promoter variant reduces risk of colorectal adenoma among nonusers of nonsteroidal anti-inflammatory drugsQ28210376
Aspirin and other nonsteroidal anti-inflammatory drugs and breast cancer incidence in a large U.S. cohortQ28213690
Characterization of the human gene (PTGS2) encoding prostaglandin-endoperoxide synthase 2Q28253346
Polymorphism in the 3'-untranslated region of TNFalpha mRNA impairs binding of the post-transcriptional regulatory protein HuR to TNFalpha mRNA.Q34229483
Targeting cyclooxygenase-2 in human neoplasia: rationale and promiseQ34287766
Cyclo-oxygenase 2: a pharmacological target for the prevention of cancer.Q34571903
Fluorescence polarization in homogeneous nucleic acid analysisQ35023029
The role of COX-2 in breast and cervical cancer.Q35148936
Dysregulated post-transcriptional control of COX-2 gene expression in cancerQ35668348
Non-steroidal anti-inflammatory drugs for the prevention and treatment of cancerQ36194125
Breast cancer and NSAID use: a meta-analysisQ36622959
Molecular classification of breast cancer: implications for selection of adjuvant chemotherapy.Q36642141
Interaction between cyclooxygenase-2 gene polymorphism and dietary n-6 polyunsaturated fatty acids on colon cancer risk: the Singapore Chinese Health StudyQ36695052
Growth differentiation factor-9 stimulates progesterone synthesis in granulosa cells via a prostaglandin E2/EP2 receptor pathwayQ37455567
COX-2 gene promoter haplotypes and prostate cancer riskQ38345290
The Long Island Breast Cancer Study Project: description of a multi-institutional collaboration to identify environmental risk factors for breast cancerQ38454025
Environmental toxins and breast cancer on Long Island. I. Polycyclic aromatic hydrocarbon DNA adductsQ38454180
Association between non-steroidal anti-inflammatory drugs (NSAIDs) and invasive breast cancer and carcinoma in situ of the breastQ40534891
Common promoter variant in cyclooxygenase-2 represses gene expression: evidence of role in acute-phase inflammatory response.Q40697859
Prostaglandin synthase 2.Q40941854
Cyclooxygenase 2 polymorphism (Val511Ala), nonsteroidal anti-inflammatory drug use and breast cancer in African American womenQ43858996
Aromatase and COX-2 expression in human breast cancersQ43890516
A polymorphism in the cyclooxygenase 2 gene as an inherited protective factor against myocardial infarction and strokeQ44103563
Colorectal adenoma risk is modified by the interplay between polymorphisms in arachidonic acid pathway genes and fish consumptionQ45154644
A common polymorphism in the 3'UTR of cyclooxygenase 2/prostaglandin synthase 2 gene and risk of lung cancer in a Chinese populationQ46390548
The cyclooxygenase-2 (PTGS2) 8473T>C polymorphism is associated with breast cancer riskQ46952833
Prospective study of nonsteroidal anti-inflammatory drugs and breast cancer.Q50636879
Peroxisome proliferator-activated [corrected] receptor-gamma2 [corrected] Pro12Ala, interaction with alcohol intake and NSAID use, in relation to risk of breast cancer in a prospective study of Danes.Q51787247
A new algorithm for haplotype-based association analysis: the Stochastic-EM algorithm.Q52001789
Identification of functional genetic variants in cyclooxygenase-2 and their association with risk of esophageal cancer.Q53355583
Polymorphism in the nuclear factor kappa-B binding promoter region of cyclooxygenase-2 is associated with an increased risk of bladder cancer.Q53629616
Genetic variants in cyclooxygenase-2: Expression and risk of gastric cancer and its precursors in a Chinese population.Q54597767
Lack of Association between Polymorphisms in Inflammatory Genes and Lung Cancer RiskQ57272147
Association of a common polymorphism in the cyclooxygenase 2 gene with risk of non-small cell lung cancerQ57610567
Expression of cyclooxygenase-1 and cyclooxygenase-2 in human breast cancerQ74376052
Genotype transposer: automated genotype manipulation for linkage disequilibrium analysisQ74428447
Prognostic significance of elevated cyclooxygenase-2 expression in breast cancerQ77601963
Correlation of cyclooxygenase-2 and aromatase immunohistochemical expression in invasive ductal carcinoma, ductal carcinoma in situ, and adjacent normal epitheliumQ81563636
Prostaglandin-endoperoxide synthase 2 (PTGS2) gene polymorphisms and risk of biliary tract cancer and gallstones: a population-based study in Shanghai, ChinaQ81638679
Increased cyclooxygenase-2 expression in duodenal compared with colonic tissues in familial adenomatous polyposis and relationship to the -765G -> C COX-2 polymorphismQ81805957
P433issue6
P407language of work or nameEnglishQ1860
P921main subjectinflammationQ101991
P304page(s)R71
P577publication date2006-01-01
P1433published inBreast Cancer ResearchQ2208481
P1476titleGenetic polymorphisms in the cyclooxygenase-2 gene, use of nonsteroidal anti-inflammatory drugs, and breast cancer risk
P478volume8

Reverse relations

cites work (P2860)
Q43294461-765G>C and 8473T>C polymorphisms of COX-2 and cancer risk: a meta-analysis based on 33 case-control studies
Q34206458A common single-nucleotide polymorphism in cyclooxygenase-2 disrupts microRNA-mediated regulation
Q38191999Aging, nutrient signaling, hematopoietic senescence, and cancer
Q36081333Association of the -14C/G MET and the -765G/C COX-2 gene polymorphisms with the risk of chronic rhinosinusitis with nasal polyps in a Polish population
Q34119332Association of the three common SNPs of cyclooxygenase-2 gene (rs20417, rs689466, and rs5275) with the susceptibility of breast cancer: an updated meta-analysis involving 34,590 subjects
Q35527962Associations between ALOX, COX, and CRP polymorphisms and breast cancer among Hispanic and non-Hispanic white women: The breast cancer health disparities study
Q28274081Cyclooxygenase-2 and cancer treatment: understanding the risk should be worth the reward
Q30367680Cyclooxygenase-2 and the inflammogenesis of breast cancer.
Q34458235Effect of COX-2 inhibitors and other non-steroidal inflammatory drugs on breast cancer risk: a meta-analysis.
Q38393725Five COX-2 gene polymorphisms and risk of breast cancer: an updated meta-analysis based on 19 case-control studies
Q36290438Genetic polymorphisms in the cyclooxygenase-1 and cyclooxygenase-2 genes and risk of colorectal adenoma
Q34351250Genetic variants in COX-2, non-steroidal anti-inflammatory drugs, and breast cancer risk: the Western New York Exposures and Breast Cancer (WEB) Study.
Q94391805Interaction between polyunsaturated fatty acids and genetic variants in relation to breast cancer incidence
Q34794017Interaction between use of non-steroidal anti-inflammatory drugs and selected genetic polymorphisms in ovarian cancer risk
Q34721693Lack of association between COX-2 8473T>C polymorphism and breast cancer risk: a meta-analysis
Q36746417Linkage disequilibrium and haplotype analysis of COX-2 and risk of colorectal adenoma development
Q36336831Mechanistic aspects of COX-2 expression in colorectal neoplasia
Q43061636Modulation of breast cancer risk by nonsteroidal anti-inflammatory drugs.
Q38444433Pharmacogenomics of cyclooxygenases
Q34294719Platelets and cancer: a casual or causal relationship: revisited.
Q41030946Polymorphisms in cyclooxygenase-2 gene in endometrial cancer patients
Q33741123Polymorphisms in regulatory regions of cyclooxygenase-2 gene and breast cancer risk in Brazilians: a case-control study
Q37769274Potentially functional COX-2-1195G>A polymorphism increases the risk of digestive system cancers: a meta-analysis
Q37475804Prognostic Significance and Clinicopathological Associations of COX-2 SNP in Patients with Nonsmall Cell Lung Cancer
Q37602314The rationale and potential of cancer chemoprevention with special emphasis on breast cancer

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