Overexpression of an ADP-ribosylation factor-guanine nucleotide exchange factor, BIG2, uncouples brefeldin A-induced adaptor protein-1 coat dissociation and membrane tubulation

scientific article (publication date: 15 March 2002)

Overexpression of an ADP-ribosylation factor-guanine nucleotide exchange factor, BIG2, uncouples brefeldin A-induced adaptor protein-1 coat dissociation and membrane tubulation is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.M112427200
P698PubMed publication ID11777925

P2093author name stringKazuhisa Nakayama
Yusaku Yoshida
Hiroyuki Takatsu
Chisa Shinotsuka
Kazumasa Kawamoto
P2860cites workPurification and cloning of a brefeldin A-inhibited guanine nucleotide-exchange protein for ADP-ribosylation factorsQ22009440
Identification and localization of two brefeldin A-inhibited guanine nucleotide-exchange proteins for ADP-ribosylation factors in a macromolecular complexQ22253338
A family of ADP-ribosylation factor effectors that can alter membrane transport through the trans-GolgiQ22253480
Separation of membrane trafficking and actin remodeling functions of ARF6 with an effector domain mutantQ22254679
Identification and characterization of novel clathrin adaptor-related proteinsQ24312080
Brefeldin A: insights into the control of membrane traffic and organelle structureQ24643698
p200 ARF-GEP1: a Golgi-localized guanine nucleotide exchange protein whose Sec7 domain is targeted by the drug brefeldin AQ24644693
GBF1: A novel Golgi-associated BFA-resistant guanine nucleotide exchange factor that displays specificity for ADP-ribosylation factor 5Q24651935
GGAs: a family of ADP ribosylation factor-binding proteins related to adaptors and associated with the Golgi complexQ24685976
Nucleotide exchange on ARF mediated by yeast Gea1 protein.Q27936330
Structure and intracellular localization of mouse ADP-ribosylation factors type 1 to type 6 (ARF1-ARF6)Q28115160
Segregation of COPI-rich and anterograde-cargo-rich domains in endoplasmic-reticulum-to-Golgi transport complexesQ28143417
Turning on ARF: the Sec7 family of guanine-nucleotide-exchange factorsQ28143666
Adaptor gamma ear homology domain conserved in gamma-adaptin and GGA proteins that interact with gamma-synerginQ28144526
Clathrin and adaptorsQ28280468
Structure and function of ARF proteins: activators of cholera toxin and critical components of intracellular vesicular transport processesQ28301965
Expression of a dominant allele of human ARF1 inhibits membrane traffic in vivoQ28567541
Endophilin I mediates synaptic vesicle formation by transfer of arachidonate to lysophosphatidic acid.Q30175352
Activation of ARF6 by ARNO stimulates epithelial cell migration through downstream activation of both Rac1 and phospholipase DQ30307678
Visualization of the dynamics of synaptic vesicle and plasma membrane proteins in living axonsQ32129557
A primer on vesicle buddingQ33603151
Lipid regulators of membrane traffic through the Golgi complexQ33632971
The role of ARF and Rab GTPases in membrane transportQ33712473
CtBP/BARS induces fission of Golgi membranes by acylating lysophosphatidic acidQ33882728
Regulators and effectors of the ARF GTPases.Q33954573
Tubulovesicular processes emerge from trans-Golgi cisternae, extend along microtubules, and interlink adjacent trans-golgi elements into a reticulumQ33976972
Dissociation of a 110-kD peripheral membrane protein from the Golgi apparatus is an early event in brefeldin A actionQ36224297
Tubulation of Golgi membranes in vivo and in vitro in the absence of brefeldin AQ36232230
Role of NAD+ and ADP-ribosylation in the maintenance of the Golgi structure.Q36274972
Golgi tubule traffic and the effects of brefeldin A visualized in living cellsQ36275025
Correlative light-electron microscopy reveals the tubular-saccular ultrastructure of carriers operating between Golgi apparatus and plasma membraneQ36301626
Biochemical dissection of AP-1 recruitment onto Golgi membranes.Q36383269
The morphology but not the function of endosomes and lysosomes is altered by brefeldin AQ36531990
Cloning and expression of a cDNA encoding a bovine brain brefeldin A-sensitive guanine nucleotide-exchange protein for ADP-ribosylation factorQ36713143
Building a secretory apparatus: role of ARF1/COPI in Golgi biogenesis and maintenanceQ40849330
Cytotoxicity of brefeldin A correlates with its inhibitory effect on membrane binding of COP coat proteinsQ41345938
Recruitment of coat proteins onto Golgi membranes in intact and permeabilized cells: effects of brefeldin A and G protein activatorsQ41629883
Brefeldin A's effects on endosomes, lysosomes, and the TGN suggest a general mechanism for regulating organelle structure and membrane trafficQ41659144
Brefeldin A causes a microtubule-mediated fusion of the trans-Golgi network and early endosomesQ41659646
Dissociation of coatomer from membranes is required for brefeldin A-induced transfer of Golgi enzymes to the endoplasmic reticulumQ42837132
Trafficking of yellow-fluorescent-protein-tagged mu1 subunit of clathrin adaptor AP-1 complex in living cellsQ43605994
Molecular cloning and functional characterization of brefeldin A-ADP-ribosylated substrate. A novel protein involved in the maintenance of the Golgi structure.Q47957307
The binding of AP-1 clathrin adaptor particles to Golgi membranes requires ADP-ribosylation factor, a small GTP-binding proteinQ48268447
Lipid membranes shape upQ59001430
P433issue11
P407language of work or nameEnglishQ1860
P921main subjectguanineQ169313
overexpressionQ61643320
P304page(s)9468-73
P577publication date2002-03-15
P1433published inJournal of Biological ChemistryQ867727
P1476titleOverexpression of an ADP-ribosylation factor-guanine nucleotide exchange factor, BIG2, uncouples brefeldin A-induced adaptor protein-1 coat dissociation and membrane tubulation
P478volume277

Reverse relations

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