Engineered human pluripotent-stem-cell-derived intestinal tissues with a functional enteric nervous system

scientific article (publication date: 21 November 2016)

Engineered human pluripotent-stem-cell-derived intestinal tissues with a functional enteric nervous system is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1038/NM.4233
P932PMC publication ID5562951
P698PubMed publication ID27869805

P50authorMaxime M MaheQ57498736
Andrew ElefantyQ77343878
Edouard G StanleyQ91105886
P2093author name stringYuichiro Miyaoka
Bruce R Conklin
Jacqueline Schiesser
Mohammad A Mandegar
Nambirajan Sundaram
Michel Neunlist
Philippe Aubert
Michael A Helmrath
Holly M Poling
Carey L Watson
James M Wells
Ching-Fang Chang
Samantha A Brugmann
Michael J Workman
Stephen Trisno
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Appearance of cholinergic myenteric neurons during enteric nervous system development: comparison of different ChAT fluorescent mouse reporter lines.Q33680578
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The enteric nervous systemQ34250716
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Microbiota controls the homeostasis of glial cells in the gut lamina propriaQ35013616
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Transplanted progenitors generate functional enteric neurons in the postnatal colonQ36638182
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Birthdating of myenteric neuron subtypes in the small intestine of the mouseQ37423421
Generating human intestinal tissue from pluripotent stem cells in vitroQ37495400
Development of the enteric nervous system and its role in intestinal motility during fetal and early postnatal stages.Q37603670
Multipotent caudal neural progenitors derived from human pluripotent stem cells that give rise to lineages of the central and peripheral nervous system.Q37696446
The enteric nervous system and neurogastroenterology.Q37990818
Development and developmental disorders of the enteric nervous systemQ38066359
Cellular changes in the enteric nervous system during ageingQ38093934
Hirschsprung disease: a developmental disorder of the enteric nervous system.Q38116935
Distinct subpopulations of enteric neuronal progenitors defined by time of development, sympathoadrenal lineage markers and Mash-1-dependence.Q38287443
Enteric nervous system assembly: Functional integration within the developing gut.Q38846945
Automated Video-Based Analysis of Contractility and Calcium Flux in Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes Cultured over Different Spatial ScalesQ39109857
Faithful expression of multiple proteins via 2A-peptide self-processing: a versatile and reliable method for manipulating brain circuits.Q39827307
A method for genetic modification of human embryonic stem cells using electroporationQ40143374
GDNF is a chemoattractant for enteric neural cells.Q40833233
Transient catecholaminergic (TC) cells in the vagus nerves and bowel of fetal mice: relationship to the development of enteric neuronsQ41275572
Directed differentiation of human pluripotent stem cells into intestinal tissue in vitroQ41770080
Modeling neural crest induction, melanocyte specification, and disease-related pigmentation defects in hESCs and patient-specific iPSCsQ42153574
Loss of enteric dopaminergic neurons and associated changes in colon motility in an MPTP mouse model of Parkinson's diseaseQ43090325
Neural stem cell therapies for enteric nervous system disordersQ43617676
Chemical coding of the human gastrointestinal nervous system: cholinergic, VIPergic, and catecholaminergic phenotypesQ44357603
Perturbation of hoxb5 signaling in vagal neural crests down-regulates ret leading to intestinal hypoganglionosis in miceQ46659431
Congenital central hypoventilation syndrome and Hirschsprung's disease in an extremely preterm infantQ47787585
Embryonic development of the ganglion plexuses and the concentric layer structure of human gut: a topographical study.Q48021523
Isolation and directed differentiation of neural crest stem cells derived from human embryonic stem cells.Q50856695
HOXB5 expression is spatially and temporarily regulated in human embryonic gut during neural crest cell colonization and differentiation of enteric neuroblasts.Q52100965
Development of the enteric nervous system, smooth muscle and interstitial cells of Cajal in the human gastrointestinal tractQ81322487
Human and mouse enteric nervous system neurosphere transplants regulate the function of aganglionic embryonic distal colonQ81366321
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectnervous systemQ9404
pluripotencyQ1894941
P304page(s)49-59
P577publication date2016-11-21
P1433published inNature MedicineQ1633234
P1476titleEngineered human pluripotent-stem-cell-derived intestinal tissues with a functional enteric nervous system
P478volume23

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