| scholarly article | Q13442814 |
| review article | Q7318358 |
| P2093 | author name string | Koichi Suzuki | |
| Hiroyuki Sorimachi | |||
| Shoji Hata | |||
| Yukiko Kawabata | |||
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | S12-8 | |
| P577 | publication date | 2004-02-01 | |
| P1433 | published in | Diabetes | Q895262 |
| P1476 | title | Structure, activation, and biology of calpain | |
| P478 | volume | 53 Suppl 1 |
| Q58696892 | A Membrane Potential- and Calpain-Dependent Reversal of Caspase-1 Inhibition Regulates Canonical NLRP3 Inflammasome |
| Q48821218 | A pharmacogenetic association between a variation in calpain 10 (CAPN10) gene and the response to metformin treatment in patients with type 2 diabetes. |
| Q48501623 | A possible therapeutic potential of quercetin through inhibition of μ-calpain in hypoxia induced neuronal injury: a molecular dynamics simulation study |
| Q37824806 | Aberrant expression of apoptosis-related molecules in endometriosis: a possible mechanism underlying the pathogenesis of endometriosis |
| Q36765901 | Activation of Calpain-2 by Mediators in Pulmonary Vascular Remodeling of Pulmonary Arterial Hypertension |
| Q28476733 | Acute toxicity of the antifouling compound butenolide in non-target organisms |
| Q24293645 | Advanced glycation end-products induce calpain-mediated degradation of ezrin |
| Q37990195 | All cut up! The consequences of calpain activation on platelet function |
| Q40301580 | Altered reactivity of tertiary mesenteric arteries following acute myocardial ischemia |
| Q36134506 | Analysis of calpain-3 protein in muscle biopsies of different muscular dystrophies from India. |
| Q42442656 | Association of Smoking With Semen Quality and µ-Calpain Level in Normospermia: A Case-Control Study |
| Q39036936 | Atrial Calpains: Mediators of Atrialmyopathies in Atrial Fibrillation |
| Q24300075 | Autolytic activity of human calpain 7 is enhanced by ESCRT-III-related protein IST1 through MIT-MIM interaction |
| Q42628242 | CAPN3 mRNA processing alteration caused by splicing mutation associated with novel genomic rearrangement of Alu elements |
| Q92558825 | CAPN5 genetic inactivation phenotype supports therapeutic inhibition trials |
| Q35882582 | CAPN5 mutation in hereditary uveitis: the R243L mutation increases calpain catalytic activity and triggers intraocular inflammation in a mouse model |
| Q36283915 | Calcium Regulates the Activity and Structural Stability of Tpr, a Bacterial Calpain-like Peptidase |
| Q45360719 | Calcium dysregulation in relation to Alzheimer-type pathology in the ageing brain. |
| Q45775611 | Calcium paradox induces apoptosis in the isolated perfused Rana ridibunda heart: involvement of p38-MAPK and calpain |
| Q40046395 | Calpain 1 and 2 are required for RNA replication of echovirus 1. |
| Q28584194 | Calpain 1 and Calpastatin expression is developmentally regulated in rat brain |
| Q43050228 | Calpain 10 homology modeling with CYGAK and increased lipophilicity leads to greater potency and efficacy in cells |
| Q24338621 | Calpain 2 activated through N-methyl-D-aspartic acid receptor signaling cleaves CPEB3 and abrogates CPEB3-repressed translation in neurons |
| Q33888505 | Calpain 5 is highly expressed in the central nervous system (CNS), carries dual nuclear localization signals, and is associated with nuclear promyelocytic leukemia protein bodies |
| Q33649868 | Calpain 8/nCL-2 and calpain 9/nCL-4 constitute an active protease complex, G-calpain, involved in gastric mucosal defense |
| Q47161675 | Calpain Inhibition Attenuates Adipose Tissue Inflammation and Fibrosis in Diet-induced Obese Mice |
| Q64122227 | Calpain Inhibition Restores Autophagy and Prevents Mitochondrial Fragmentation in a Human iPSC Model of Diabetic Endotheliopathy |
| Q35157505 | Calpain chronicle--an enzyme family under multidisciplinary characterization |
| Q33894681 | Calpain cleavage prediction using multiple kernel learning. |
| Q48725567 | Calpain inhibitor MDL 28170 protects against the Ca2+ paradox in rat hearts |
| Q41876653 | Calpain inhibitor SNJ-1945 attenuates events prior to angiogenesis in cultured human retinal endothelial cells |
| Q36801466 | Calpain inhibitor reduces cancer-induced bone pain possibly through inhibition of osteoclastogenesis in rat cancer-induced bone pain model |
| Q39661641 | Calpain inhibitors reduce retinal hypoxia in ischemic retinopathy by improving neovascular architecture and functional perfusion |
| Q37857282 | Calpain inhibitors: a survey of compounds reported in the patent and scientific literature |
| Q30429980 | Calpain mediates pulmonary vascular remodeling in rodent models of pulmonary hypertension, and its inhibition attenuates pathologic features of disease |
| Q33973418 | Calpain protects the heart from hemodynamic stress |
| Q38234563 | Calpain system and its involvement in myocardial ischemia and reperfusion injury |
| Q90398287 | Calpain-10 drives podocyte apoptosis and renal injury in diabetic nephropathy |
| Q33784601 | Calpain-10 is a component of the obesity-related quantitative trait locus Adip1. |
| Q59329092 | Calpain-10 regulates actin dynamics by proteolysis of microtubule-associated protein 1B |
| Q57414617 | Calpain-10 variants and haplotypes are associated with polycystic ovary syndrome in Caucasians |
| Q34435033 | Calpain-10: from genome search to function. |
| Q28535028 | Calpain-6 deficiency promotes skeletal muscle development and regeneration |
| Q39947179 | Calpain-mediated androgen receptor breakdown in apoptotic prostate cancer cells |
| Q89985530 | Calpain-mediated cleavage of p53 in human cytomegalovirus-infected lung fibroblasts |
| Q53088604 | Calpain2 protease: A new member of the Wnt/Ca(2+) pathway modulating convergent extension movements in Xenopus. |
| Q33565470 | Calpain3 is expressed in a proteolitically active form in papillomavirus-associated urothelial tumors of the urinary bladder in cattle |
| Q37324405 | Calpain5 expression is decreased in endometriosis and regulated by HOXA10 in human endometrial cells |
| Q39144278 | Calpains are required for invasive and metastatic potentials of human HCC cells |
| Q28507146 | Calpains mediate epithelial-cell death during mammary gland involution: mitochondria and lysosomal destabilization |
| Q38009779 | Calpains, mitochondria, and apoptosis |
| Q53421991 | Calpastatin, an endogenous calpain-inhibitor protein, regulates the cleavage of the Cdk5 activator p35 to p25. |
| Q24309140 | Capns1, a new binding partner of RasGAP-SH3 domain in K-Ras(V12) oncogenic cells: modulation of cell survival and migration |
| Q24654460 | Cellular interplay between neurons and glia: toward a comprehensive mechanism for excitotoxic neuronal loss in neurodegeneration |
| Q37557828 | Chapter 4. Peptidases of trematodes |
| Q51964579 | Characterization and comparative expression of zebrafish calpain system genes during early development. |
| Q34600254 | Cisplatin-induced apoptosis inhibits autophagy, which acts as a pro-survival mechanism in human melanoma cells |
| Q47165501 | Co-conspirators in a new mechanism for the degradation of Δ9-desaturase |
| Q34298023 | Comprehensive survey of p94/calpain 3 substrates by comparative proteomics--possible regulation of protein synthesis by p94. |
| Q87423379 | Computational investigation of the key factors affecting the second stage activation mechanisms of domain II m-calpain |
| Q27652953 | Concerted multi-pronged attack by calpastatin to occlude the catalytic cleft of heterodimeric calpains |
| Q42590164 | Constitutive activation of the pH-responsive Rim101 pathway in yeast mutants defective in late steps of the MVB/ESCRT pathway |
| Q79387221 | Cross-talk between calpain and caspase-3/-7 in cisplatin-induced apoptosis of melanoma cells: a major role of calpain inhibition in cell death protection and p53 status |
| Q37087283 | Decreased expression of Calpain-9 predicts unfavorable prognosis in patients with gastric cancer |
| Q36201829 | Deficiency of Capn4 gene inhibits nuclear factor-κB (NF-κB) protein signaling/inflammation and reduces remodeling after myocardial infarction |
| Q35672928 | Delivery of Topically Applied Calpain Inhibitory Peptide to the Posterior Segment of the Rat Eye |
| Q34533516 | Different roles for contracture and calpain in calcium paradox-induced heart injury |
| Q24306130 | Differential contribution of Puma and Noxa in dual regulation of p53-mediated apoptotic pathways |
| Q51523100 | Differential functions of calpain 1 during epithelial cell death and adipocyte differentiation in mammary gland involution. |
| Q50472537 | Differential role of calpain-dependent protein cleavage in intermediate and long-term operant memory in Aplysia. |
| Q46122899 | Distinguishing between calpain heterodimerization and homodimerization |
| Q34028669 | Dynamic distribution of muscle-specific calpain in mice has a key role in physical-stress adaptation and is impaired in muscular dystrophy. |
| Q38704976 | ENaC activity is regulated by calpain-2 proteolysis of MARCKS proteins |
| Q57973234 | Eccentric contractions lead to myofibrillar dysfunction in muscular dystrophy |
| Q48432923 | Effect of magnesium sulfate on the osmotic fragility and lipid peroxidation of intact red blood cells from pregnant women with severe preeclampsia |
| Q34635153 | Effect of nutrient restriction and re-feeding on calpain family genes in skeletal muscle of channel catfish (Ictalurus punctatus) |
| Q59239674 | Effects of selected myofibrillar protein activities on beef tenderization process based on electrophoretic analysis |
| Q37377194 | Elevated Expression of Calpain-4 Predicts Poor Prognosis in Patients with Gastric Cancer after Gastrectomy |
| Q38052761 | From genotype to human β cell phenotype and beyond |
| Q42412803 | Further characterization of the signaling proteolysis step in the Aspergillus nidulans pH signal transduction pathway. |
| Q34545768 | GWAS identifies four novel eosinophilic esophagitis loci |
| Q35072053 | Galectin-3 secretion and tyrosine phosphorylation is dependent on the calpain small subunit, Calpain 4 |
| Q24672249 | Genes, diet and type 2 diabetes mellitus: a review |
| Q59049526 | Genetic Markers of Polycystic Ovary Syndrome: Emphasis on Insulin Resistance |
| Q33755662 | Homology modeling study of bovine μ-calpain inhibitor-binding domains. |
| Q36098867 | Hypoxia Activates Calpains in the Nerve Fiber Layer of Monkey Retinal Explants |
| Q33572036 | Identification and optimization of a novel inhibitor of mitochondrial calpain 10 |
| Q36643383 | Identification of active Plasmodium falciparum calpain to establish screening system for Pf-calpain-based drug development |
| Q33826073 | Identification of calpain substrates by ORF phage display |
| Q36068283 | In vitro and in vivo effects of HIV protease inhibitors on apoptosis |
| Q30490856 | Inhibition of calpain increases LIS1 expression and partially rescues in vivo phenotypes in a mouse model of lissencephaly |
| Q41951212 | Insulin, insulin resistance, and platelet signaling in diabetes |
| Q42118651 | Interactions with M-band titin and calpain 3 link myospryn (CMYA5) to tibial and limb-girdle muscular dystrophies |
| Q34991527 | Intracellular ANKRD1 protein levels are regulated by 26S proteasome-mediated degradation |
| Q38322158 | Involvement of calpain-calpastatin in cigarette smoke-induced inhibition of lung endothelial nitric oxide synthase |
| Q34043503 | KAP degradation by calpain is associated with CK2 phosphorylation and provides a novel mechanism for cyclosporine A-induced proximal tubule injury |
| Q33863846 | LabCaS: labeling calpain substrate cleavage sites from amino acid sequence using conditional random fields |
| Q28578452 | Loss of calpain 10 causes mitochondrial dysfunction during chronic hyperglycemia |
| Q36146335 | Membrane Repair: Mechanisms and Pathophysiology. |
| Q45146040 | Microarray analysis of differentially expressed genes in rat frontal cortex under chronic risperidone treatment |
| Q37295056 | Mitochondrial abnormalities, energy deficit and oxidative stress are features of calpain 3 deficiency in skeletal muscle |
| Q35674605 | Mitochondrial calpain 10 is degraded by Lon protease after oxidant injury |
| Q37526353 | Mitochondrial membrane permeabilization in neuronal injury |
| Q92293297 | Molecular characterization and functional analysis of the Schistosoma mekongi Ca2+-dependent cysteine protease (calpain) |
| Q24319118 | Multiple molecular interactions implicate the connectin/titin N2A region as a modulating scaffold for p94/calpain 3 activity in skeletal muscle |
| Q52659218 | Mycobacterium fortuitum-induced ER-Mitochondrial calcium dynamics promotes calpain/caspase-12/caspase-9 mediated apoptosis in fish macrophages. |
| Q33279373 | Myogenic stage, sarcomere length, and protease activity modulate localization of muscle-specific calpain |
| Q40037129 | N terminus of calpain 1 is a mitochondrial targeting sequence |
| Q26799250 | Natural Compounds from Saffron and Bear Bile Prevent Vision Loss and Retinal Degeneration |
| Q36947169 | Neuroprotection in glaucoma using calpain-1 inhibitors: regional differences in calpain-1 activity in the trabecular meshwork, optic nerve and implications for therapeutics |
| Q35081723 | Neuroprotective strategies against calpain-mediated neurodegeneration |
| Q35282636 | Nicotinic acetylcholine receptor α1 promotes calpain-1 activation and macrophage inflammation in hypercholesterolemic nephropathy |
| Q34664340 | Non-proteolytic functions of calpain-3 in sarcoplasmic reticulum in skeletal muscles. |
| Q24318456 | Novel variants of muscle calpain 3 identified in human melanoma cells: cisplatin-induced changes in vitro and differential expression in melanocytic lesions |
| Q58770910 | Over-expression of calpastatin attenuates myocardial injury following myocardial infarction by inhibiting endoplasmic reticulum stress |
| Q33757275 | Oxidants and Ca+2 induce PGC-1alpha degradation through calpain |
| Q99605020 | Pharmacogenetics of Type 2 Diabetes-Progress and Prospects |
| Q34342521 | Phevalin (aureusimine B) production by Staphylococcus aureus biofilm and impacts on human keratinocyte gene expression. |
| Q37316717 | Photoreceptor cell death mechanisms in inherited retinal degeneration. |
| Q37812402 | Physiologic and pathophysiologic role of calpain: implications for the occurrence of atrial fibrillation |
| Q35796859 | Physiological Roles of Calpain 1 Associated to Multiprotein NMDA Receptor Complex |
| Q37426834 | Poly(ADP-ribose) signals to mitochondrial AIF: a key event in parthanatos |
| Q82448666 | Possible functions of p94 in connectin-mediated signaling pathways in skeletal muscle cells |
| Q34468979 | Prion pathogenesis is faithfully reproduced in cerebellar organotypic slice cultures. |
| Q34712688 | Regional development of uterine decidualization: molecular signaling by Hoxa-10. |
| Q36239537 | Regulation and physiological roles of the calpain system in muscular disorders |
| Q42998566 | Regulation of TET protein stability by calpains. |
| Q52721187 | Regulatory role of calpain in neuronal death. |
| Q38574681 | Resuscitation of a dead cardiomyocyte |
| Q38090928 | Role of calpain in apoptosis. |
| Q37438390 | Role of calpains in the injury-induced dysfunction and degeneration of the mammalian axon |
| Q37899085 | Role of various proteases in cardiac remodeling and progression of heart failure |
| Q51439096 | Sequential cleavage of insulin receptor by calpain 2 and γ-secretase impairs insulin signalling. |
| Q28508166 | Skeletal muscle-specific calpain is an intracellular Na+-dependent protease |
| Q39543557 | Small-angle X-ray scattering of calpain-5 reveals a highly open conformation among calpains. |
| Q38315864 | Stomach-specific calpain, nCL-2, localizes in mucus cells and proteolyzes the beta-subunit of coatomer complex, beta-COP. |
| Q47035960 | Stomach-specific calpain, nCL-2/calpain 8, is active without calpain regulatory subunit and oligomerizes through C2-like domains |
| Q42972216 | Substrate specificity and the effect of calcium on Trypanosoma brucei metacaspase 2. |
| Q34515641 | Suppressed disassembly of autolyzing p94/CAPN3 by N2A connectin/titin in a genetic reporter system. |
| Q55714731 | Suppression of AURKA alleviates p27 inhibition on Bax cleavage and induces more intensive apoptosis in gastric cancer. |
| Q40205378 | Suppression of calpain-dependent cleavage of the CDK5 activator p35 to p25 by site-specific phosphorylation |
| Q91226507 | Systematic spatiotemporal mapping reveals divergent cell death pathways in three mouse models of hereditary retinal degeneration |
| Q35404816 | Targeted inhibition of calpain reduces myocardial hypertrophy and fibrosis in mouse models of type 1 diabetes |
| Q33912118 | Targeting Cellular Calcium Homeostasis to Prevent Cytokine-Mediated Beta Cell Death |
| Q34247526 | Tau phosphorylation and μ-calpain activation mediate the dexamethasone-induced inhibition on the insulin-stimulated Akt phosphorylation |
| Q35151516 | Tear me down: role of calpain in the development of cardiac ventricular hypertrophy |
| Q37579056 | The calpain system as a potential target for pelvic muscle reinforcement |
| Q38056782 | The cellular decision between apoptosis and autophagy |
| Q41987507 | The human blood parasite Schistosoma mansoni expresses extracellular tegumental calpains that cleave the blood clotting protein fibronectin |
| Q37113015 | The role of calcium-activated protease calpain in experimental retinal pathology |
| Q37338608 | The role of proteolytic cellular systems in trabecular meshwork homeostasis |
| Q46682087 | Type 2 diabetes candidate gene CAPN10: first, but not last |
| Q36095054 | Type 2 diabetes: principles of pathogenesis and therapy |
| Q51190794 | Use of recombinant calpain-2 siRNA adenovirus to assess calpain-2 modulation of lung endothelial cell migration and proliferation. |
| Q81778506 | [Genetics of type 2 diabetes] |
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