Specificity of molecular recognition learned from the crystal structures of TRAIL and the TRAIL:sDR5 complex

scientific article

Specificity of molecular recognition learned from the crystal structures of TRAIL and the TRAIL:sDR5 complex is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1016/S0083-6729(04)67001-4
P698PubMed publication ID15110168

P2093author name stringSun-Shin Cha
Byung-Ha Oh
Young-Lan Song
P2860cites workTriggering cell death: the crystal structure of Apo2L/TRAIL in a complex with death receptor 5Q22010751
Caspase-10 is recruited to and activated at the native TRAIL and CD95 death-inducing signalling complexes in a FADD-dependent manner but can not functionally substitute caspase-8.Q24305298
The receptor for the cytotoxic ligand TRAILQ24310481
Osteoprotegerin: a novel secreted protein involved in the regulation of bone densityQ24313918
TRAIL-R2: a novel apoptosis-mediating receptor for TRAIL.Q24314730
Cloning and characterization of TRAIL-R3, a novel member of the emerging TRAIL receptor familyQ24315643
Identification and characterization of a new member of the TNF family that induces apoptosisQ24318423
The novel receptor TRAIL-R4 induces NF-kappaB and protects against TRAIL-mediated apoptosis, yet retains an incomplete death domainQ24320162
Induction of apoptosis by Apo-2 ligand, a new member of the tumor necrosis factor cytokine familyQ24320301
2.8 A resolution crystal structure of human TRAIL, a cytokine with selective antitumor activityQ27619603
Differential hepatocyte toxicity of recombinant Apo2L/TRAIL versionsQ73704158
Apoptosis induced in normal human hepatocytes by tumor necrosis factor-related apoptosis-inducing ligandQ73766150
TRAIL: a molecule with multiple receptors and control mechanismsQ77485552
Structure of the TRAIL-DR5 complex reveals mechanisms conferring specificity in apoptotic initiationQ27620110
A unique zinc-binding site revealed by a high-resolution X-ray structure of homotrimeric Apo2L/TRAILQ27621107
Crystal structure of TRAIL-DR5 complex identifies a critical role of the unique frame insertion in conferring recognition specificityQ27625357
Crystal structure of the TRANCE/RANKL cytokine reveals determinants of receptor-ligand specificityQ27635130
Crystal structure of the extracellular domain of mouse RANK ligand at 2.2-A resolutionQ27636573
Crystal structure of extracellular human BAFF, a TNF family member that stimulates B lymphocytesQ27637597
Crystal structure of sTALL-1 reveals a virus-like assembly of TNF family ligandsQ27637902
Structural basis of BLyS receptor recognitionQ27638026
Crystal structure of the BAFF–BAFF-R complex and its implications for receptor activationQ27641056
Ligand-receptor binding revealed by the TNF family member TALL-1Q27641102
BAFF/BLyS receptor 3 comprises a minimal TNF receptor-like module that encodes a highly focused ligand-binding siteQ27641286
Crystal structure of the soluble human 55 kd TNF receptor-human TNF beta complex: implications for TNF receptor activationQ27732032
2 A crystal structure of an extracellular fragment of human CD40 ligandQ27732546
Structures of the extracellular domain of the type I tumor necrosis factor receptorQ27733974
High resolution crystal structure of a human tumor necrosis factor-alpha mutant with low systemic toxicityQ27748818
Temperature-sensitive differential affinity of TRAIL for its receptors. DR5 is the highest affinity receptorQ28142274
Apo2L/TRAIL: apoptosis signaling, biology, and potential for cancer therapyQ28176737
The TNF and TNF receptor superfamilies: integrating mammalian biologyQ28203717
An antagonist decoy receptor and a death domain-containing receptor for TRAILQ28245153
Control of TRAIL-induced apoptosis by a family of signaling and decoy receptorsQ28245164
A novel receptor for Apo2L/TRAIL contains a truncated death domainQ28255451
FADD/MORT1 and caspase-8 are recruited to TRAIL receptors 1 and 2 and are essential for apoptosis mediated by TRAIL receptor 2Q28609079
Safety and antitumor activity of recombinant soluble Apo2 ligandQ33855449
Critical role for tumor necrosis factor-related apoptosis-inducing ligand in immune surveillance against tumor developmentQ33956982
The molecular architecture of the TNF superfamilyQ34109796
Osteoprotegerin is a receptor for the cytotoxic ligand TRAIL.Q34469691
Apo2L/TRAIL and its death and decoy receptorsQ34532325
Targeting death and decoy receptors of the tumour-necrosis factor superfamilyQ34791120
TRAIL-induced eradication of primary tumour cells from multiple myeloma patient bone marrows is not related to TRAIL receptor expression or prior chemotherapyQ40776719
Tumoricidal activity of tumor necrosis factor-related apoptosis-inducing ligand in vivo.Q40975748
Functional discrepancies between tumor necrosis factor and lymphotoxin alpha explained by trimer stability and distinct receptor interactions.Q41315972
Apo2L/TRAIL-dependent recruitment of endogenous FADD and caspase-8 to death receptors 4 and 5.Q41747264
Structure of tumour necrosis factorQ41792389
Functional analysis of tumour necrosis factor-alpha-related apoptosis-inducing ligand (TRAIL): cysteine-230 plays a critical role in the homotrimerization and biological activity of this novel tumoricidal cytokineQ42751498
Increased susceptibility to tumor initiation and metastasis in TNF-related apoptosis-inducing ligand-deficient miceQ43860748
Characterization of the in vivo function of TNF-alpha-related apoptosis-inducing ligand, TRAIL/Apo2L, using TRAIL/Apo2L gene-deficient miceQ44124109
Involvement of tumor necrosis factor-related apoptosis-inducing ligand in surveillance of tumor metastasis by liver natural killer cellsQ60489570
Cysteine 230 is essential for the structure and activity of the cytotoxic ligand TRAILQ73626815
P407language of work or nameEnglishQ1860
P921main subjectcrystal structureQ895901
P304page(s)1-17
P577publication date2004-01-01
P1433published inVitamins and HormonesQ15753296
P1476titleSpecificity of molecular recognition learned from the crystal structures of TRAIL and the TRAIL:sDR5 complex
P478volume67

Reverse relations

cites work (P2860)
Q37832083Combined modality therapy with TRAIL or agonistic death receptor antibodies.
Q33674881TRAIL mutant membrane penetrating peptide alike-MuR6-TR enhances the antitumor effects of TRAIL in pancreatic carcinoma both in vitro and in vivo

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