review article | Q7318358 |
scholarly article | Q13442814 |
P356 | DOI | 10.1016/S0083-6729(04)67001-4 |
P698 | PubMed publication ID | 15110168 |
P2093 | author name string | Sun-Shin Cha | |
Byung-Ha Oh | |||
Young-Lan Song | |||
P2860 | cites work | Triggering cell death: the crystal structure of Apo2L/TRAIL in a complex with death receptor 5 | Q22010751 |
Caspase-10 is recruited to and activated at the native TRAIL and CD95 death-inducing signalling complexes in a FADD-dependent manner but can not functionally substitute caspase-8. | Q24305298 | ||
The receptor for the cytotoxic ligand TRAIL | Q24310481 | ||
Osteoprotegerin: a novel secreted protein involved in the regulation of bone density | Q24313918 | ||
TRAIL-R2: a novel apoptosis-mediating receptor for TRAIL. | Q24314730 | ||
Cloning and characterization of TRAIL-R3, a novel member of the emerging TRAIL receptor family | Q24315643 | ||
Identification and characterization of a new member of the TNF family that induces apoptosis | Q24318423 | ||
The novel receptor TRAIL-R4 induces NF-kappaB and protects against TRAIL-mediated apoptosis, yet retains an incomplete death domain | Q24320162 | ||
Induction of apoptosis by Apo-2 ligand, a new member of the tumor necrosis factor cytokine family | Q24320301 | ||
2.8 A resolution crystal structure of human TRAIL, a cytokine with selective antitumor activity | Q27619603 | ||
Differential hepatocyte toxicity of recombinant Apo2L/TRAIL versions | Q73704158 | ||
Apoptosis induced in normal human hepatocytes by tumor necrosis factor-related apoptosis-inducing ligand | Q73766150 | ||
TRAIL: a molecule with multiple receptors and control mechanisms | Q77485552 | ||
Structure of the TRAIL-DR5 complex reveals mechanisms conferring specificity in apoptotic initiation | Q27620110 | ||
A unique zinc-binding site revealed by a high-resolution X-ray structure of homotrimeric Apo2L/TRAIL | Q27621107 | ||
Crystal structure of TRAIL-DR5 complex identifies a critical role of the unique frame insertion in conferring recognition specificity | Q27625357 | ||
Crystal structure of the TRANCE/RANKL cytokine reveals determinants of receptor-ligand specificity | Q27635130 | ||
Crystal structure of the extracellular domain of mouse RANK ligand at 2.2-A resolution | Q27636573 | ||
Crystal structure of extracellular human BAFF, a TNF family member that stimulates B lymphocytes | Q27637597 | ||
Crystal structure of sTALL-1 reveals a virus-like assembly of TNF family ligands | Q27637902 | ||
Structural basis of BLyS receptor recognition | Q27638026 | ||
Crystal structure of the BAFF–BAFF-R complex and its implications for receptor activation | Q27641056 | ||
Ligand-receptor binding revealed by the TNF family member TALL-1 | Q27641102 | ||
BAFF/BLyS receptor 3 comprises a minimal TNF receptor-like module that encodes a highly focused ligand-binding site | Q27641286 | ||
Crystal structure of the soluble human 55 kd TNF receptor-human TNF beta complex: implications for TNF receptor activation | Q27732032 | ||
2 A crystal structure of an extracellular fragment of human CD40 ligand | Q27732546 | ||
Structures of the extracellular domain of the type I tumor necrosis factor receptor | Q27733974 | ||
High resolution crystal structure of a human tumor necrosis factor-alpha mutant with low systemic toxicity | Q27748818 | ||
Temperature-sensitive differential affinity of TRAIL for its receptors. DR5 is the highest affinity receptor | Q28142274 | ||
Apo2L/TRAIL: apoptosis signaling, biology, and potential for cancer therapy | Q28176737 | ||
The TNF and TNF receptor superfamilies: integrating mammalian biology | Q28203717 | ||
An antagonist decoy receptor and a death domain-containing receptor for TRAIL | Q28245153 | ||
Control of TRAIL-induced apoptosis by a family of signaling and decoy receptors | Q28245164 | ||
A novel receptor for Apo2L/TRAIL contains a truncated death domain | Q28255451 | ||
FADD/MORT1 and caspase-8 are recruited to TRAIL receptors 1 and 2 and are essential for apoptosis mediated by TRAIL receptor 2 | Q28609079 | ||
Safety and antitumor activity of recombinant soluble Apo2 ligand | Q33855449 | ||
Critical role for tumor necrosis factor-related apoptosis-inducing ligand in immune surveillance against tumor development | Q33956982 | ||
The molecular architecture of the TNF superfamily | Q34109796 | ||
Osteoprotegerin is a receptor for the cytotoxic ligand TRAIL. | Q34469691 | ||
Apo2L/TRAIL and its death and decoy receptors | Q34532325 | ||
Targeting death and decoy receptors of the tumour-necrosis factor superfamily | Q34791120 | ||
TRAIL-induced eradication of primary tumour cells from multiple myeloma patient bone marrows is not related to TRAIL receptor expression or prior chemotherapy | Q40776719 | ||
Tumoricidal activity of tumor necrosis factor-related apoptosis-inducing ligand in vivo. | Q40975748 | ||
Functional discrepancies between tumor necrosis factor and lymphotoxin alpha explained by trimer stability and distinct receptor interactions. | Q41315972 | ||
Apo2L/TRAIL-dependent recruitment of endogenous FADD and caspase-8 to death receptors 4 and 5. | Q41747264 | ||
Structure of tumour necrosis factor | Q41792389 | ||
Functional analysis of tumour necrosis factor-alpha-related apoptosis-inducing ligand (TRAIL): cysteine-230 plays a critical role in the homotrimerization and biological activity of this novel tumoricidal cytokine | Q42751498 | ||
Increased susceptibility to tumor initiation and metastasis in TNF-related apoptosis-inducing ligand-deficient mice | Q43860748 | ||
Characterization of the in vivo function of TNF-alpha-related apoptosis-inducing ligand, TRAIL/Apo2L, using TRAIL/Apo2L gene-deficient mice | Q44124109 | ||
Involvement of tumor necrosis factor-related apoptosis-inducing ligand in surveillance of tumor metastasis by liver natural killer cells | Q60489570 | ||
Cysteine 230 is essential for the structure and activity of the cytotoxic ligand TRAIL | Q73626815 | ||
P407 | language of work or name | English | Q1860 |
P921 | main subject | crystal structure | Q895901 |
P304 | page(s) | 1-17 | |
P577 | publication date | 2004-01-01 | |
P1433 | published in | Vitamins and Hormones | Q15753296 |
P1476 | title | Specificity of molecular recognition learned from the crystal structures of TRAIL and the TRAIL:sDR5 complex | |
P478 | volume | 67 |
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