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P50 | author | David E. Levy | Q39631582 |
Ricky W Johnstone | Q42384442 | ||
Daniel J Gough | Q55473952 | ||
Nicole L Messina | Q56513475 | ||
P2093 | author name string | Christopher J P Clarke | |
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Identification of genes differentially regulated by interferon alpha, beta, or gamma using oligonucleotide arrays | Q28646554 | ||
Stats: transcriptional control and biological impact | Q29547776 | ||
Paradoxical roles of the immune system during cancer development | Q29614305 | ||
Virus induction of human IFN beta gene expression requires the assembly of an enhanceosome | Q29616850 | ||
Distinct and essential roles of transcription factors IRF-3 and IRF-7 in response to viruses for IFN-alpha/beta gene induction | Q29620054 | ||
Interferon-beta pretreatment of conventional and plasmacytoid human dendritic cells enhances their activation by influenza virus | Q33381621 | ||
Modulation of SOCS protein expression influences the interferon responsiveness of human melanoma cells | Q33557548 | ||
Functional crosstalk between type I and II interferon through the regulated expression of STAT1. | Q33570493 | ||
Structure and function of the interferon-beta enhanceosome | Q33671579 | ||
A null mutation in the gene encoding a type I interferon receptor component eliminates antiproliferative and antiviral responses to interferons alpha and beta and alters macrophage responses | Q33771205 | ||
Partial impairment of cytokine responses in Tyk2-deficient mice | Q33924660 | ||
Functional classification of interferon-stimulated genes identified using microarrays | Q33951179 | ||
Deficiency of the type I interferon receptor protects mice from experimental lupus | Q34016334 | ||
Mutational switch of an IL-6 response to an interferon-gamma-like response | Q34031049 | ||
Defining emerging roles for NF-κB in antivirus responses: revisiting the interferon-β enhanceosome paradigm | Q34055270 | ||
Interferon messenger RNA is produced constitutively in the organs of normal individuals | Q34641073 | ||
Distinct roles for the NF-kappa B RelA subunit during antiviral innate immune responses | Q34742996 | ||
Type 1 interferon induction of natural killer cell gamma interferon production for defense during lymphocytic choriomeningitis virus infection | Q35149011 | ||
Control of T cell viability | Q35698562 | ||
Modulation of STAT1 protein levels: a mechanism shaping CD8 T-cell responses in vivo | Q35850004 | ||
IFN-beta in rheumatoid arthritis | Q35880785 | ||
Selective contribution of IFN-alpha/beta signaling to the maturation of dendritic cells induced by double-stranded RNA or viral infection | Q35978569 | ||
Normal human epidermis contains an interferon-like protein | Q36215434 | ||
High basal STAT4 balanced by STAT1 induction to control type 1 interferon effects in natural killer cells. | Q36228978 | ||
Basal expression levels of IFNAR and Jak-STAT components are determinants of cell-type-specific differences in cardiac antiviral responses | Q36315128 | ||
Fatal leukemia in interleukin 15 transgenic mice follows early expansions in natural killer and memory phenotype CD8+ T cells. | Q36369031 | ||
Demonstration of an interferon gamma-dependent tumor surveillance system in immunocompetent mice | Q36497106 | ||
Biologic Effects of Interferons | Q36612328 | ||
Interferon-beta1b in multiple sclerosis | Q36752915 | ||
Endogenous interferon production by endotoxin-responsive macrophages provides an autostimulatory differentiation signal | Q37076337 | ||
The transcriptional code of human IFN-beta gene expression | Q37684189 | ||
Interactions between gut microbiota and host metabolism predisposing to obesity and diabetes | Q37827867 | ||
Type I interferon in organ-targeted autoimmune and inflammatory diseases | Q37838003 | ||
Regulation of effector and memory T-cell functions by type I interferon | Q37841676 | ||
Genomic view of IFN-alpha response in pre-autoimmune NZB/W and MRL/lpr mice | Q38298730 | ||
The specificity of innate immune responses is enforced by repression of interferon response elements by NF-κB p50 | Q39587742 | ||
NF-kappa B RelA subunit is crucial for early IFN-beta expression and resistance to RNA virus replication | Q39683125 | ||
Expression of SOCS-1, suppressor of cytokine signalling-1, in human melanoma | Q40514922 | ||
Chronic myeloid leukemia cells resistant to interferon-alpha lack STAT1 expression | Q40741810 | ||
IFN-gamma priming up-regulates IFN-stimulated gene factor 3 (ISGF3) components, augmenting responsiveness of IFN-resistant melanoma cells to type I IFNs. | Q41038934 | ||
Interferon-alpha resistance in a cutaneous T-cell lymphoma cell line is associated with lack of STAT1 expression. | Q41071715 | ||
Interferon-resistant human melanoma cells are deficient in ISGF3 components, STAT1, STAT2, and p48-ISGF3gamma. | Q41082105 | ||
Is interferon produced in physiologic conditions? | Q41538283 | ||
Correlation between interferon (IFN) alpha resistance and deletion of the IFN alpha/beta genes in acute leukemia cell lines suggests selection against the IFN system | Q41611115 | ||
Rheumatoid arthritis induced by alpha-interferon therapy | Q41918975 | ||
GM-CSF- and M-CSF-dependent macrophage phenotypes display differential dependence on type I interferon signaling. | Q42453025 | ||
Fos and jun proteins are specifically expressed during differentiation of human keratinocytes | Q42472984 | ||
Differential expression of phosphorylated NF-kappaB/RelA in normal and psoriatic epidermis and downregulation of NF-kappaB in response to treatment with etanercept | Q42479845 | ||
Targeted disruption of the p50 subunit of NF-kappa B leads to multifocal defects in immune responses | Q42488424 | ||
Distinct requirements for IFNs and STAT1 in NK cell function | Q42494660 | ||
Contribution of interferon-beta to the murine macrophage response to the toll-like receptor 4 agonist, lipopolysaccharide | Q42499800 | ||
Psoriatic lesional skin exhibits an aberrant expression pattern of interferon regulatory factor-2 (IRF-2). | Q42528591 | ||
Distinct clinical courses in type 1 diabetes mellitus induced by peg-interferon-alpha treatment for chronic hepatitis C. | Q43146940 | ||
Interferon-beta is required for interferon-alpha production in mouse fibroblasts | Q43412872 | ||
Cross talk of the interferon-alpha/beta signalling complex with gp130 for effective interleukin-6 signalling | Q43688291 | ||
Effect of exercise on plasma interferon levels | Q44187100 | ||
IFNalpha activates dormant haematopoietic stem cells in vivo. | Q44358922 | ||
Constitutive IFN-alpha/beta signal for efficient IFN-alpha/beta gene induction by virus | Q45736557 | ||
Interferon regulatory factor-2 protects quiescent hematopoietic stem cells from type I interferon-dependent exhaustion. | Q45988825 | ||
A critical function for type I interferons in cancer immunoediting | Q46542397 | ||
IFN-beta gene deletion leads to augmented and chronic demyelinating experimental autoimmune encephalomyelitis. | Q52550265 | ||
Interferon system defects in malignant T-cells. | Q52826947 | ||
Type I IFN modulates innate and specific antiviral immunity. | Q52920823 | ||
Induction of dendritic cell differentiation by IFN-alpha in systemic lupus erythematosus. | Q53718320 | ||
STAT3 negatively regulates type I IFN-mediated antiviral response. | Q54356093 | ||
Critical role for constitutive type I interferon signaling in the prevention of cellular transformation. | Q54503356 | ||
Activation of the interferon-alpha pathway identifies a subgroup of systemic lupus erythematosus patients with distinct serologic features and active disease. | Q54664586 | ||
Type I IFN negatively regulates CD8+ T cell responses through IL-10-producing CD4+ T regulatory 1 cells | Q56881042 | ||
Interferon-induced nuclear factors that bind a shared promoter element correlate with positive and negative transcriptional control | Q57055074 | ||
RANKL maintains bone homeostasis through c-Fos-dependent induction of interferon-β | Q57675150 | ||
Sensitization of IFN-γ Jak-STAT signaling during macrophage activation | Q60595376 | ||
Type I interferons produced by dendritic cells promote their phenotypic and functional activation | Q61473768 | ||
The down-regulation of alpha-interferon receptors in human lymphoblastoid cells: relation to cellular responsiveness to the antiproliferative action of alpha-interferon | Q68415965 | ||
P433 | issue | 2 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | infectious disease | Q18123741 |
P304 | page(s) | 166-74 | |
P577 | publication date | 2012-02-24 | |
P1433 | published in | Immunity | Q6005457 |
P1476 | title | Constitutive type I interferon modulates homeostatic balance through tonic signaling | |
P478 | volume | 36 |
Q28118033 | A BRISC-SHMT complex deubiquitinates IFNAR1 and regulates interferon responses |
Q91564570 | A molecular switch from STAT2-IRF9 to ISGF3 underlies interferon-induced gene transcription |
Q35568496 | A robust type I interferon gene signature from blood RNA defines quantitative but not qualitative differences between three major IFNβ drugs in the treatment of multiple sclerosis |
Q33710852 | AGO2 Negatively Regulates Type I Interferon Signaling Pathway by Competition Binding IRF3 with CBP/p300. |
Q58701377 | ATP/P2X7 receptor signaling as a potential anti-inflammatory target of natural polyphenols |
Q39071091 | Absent in Melanoma 2 proteins in SLE. |
Q36736634 | Activation of RNase L by Murine Coronavirus in Myeloid Cells Is Dependent on Basal Oas Gene Expression and Independent of Virus-Induced Interferon |
Q52680802 | Alpha/Beta Interferon (IFN-α/β) Signaling in Astrocytes Mediates Protection against Viral Encephalomyelitis and Regulates IFN-γ-Dependent Responses. |
Q38723712 | Alpha/beta interferon receptor deficiency in mice significantly enhances susceptibility of the animals to pseudorabies virus infection |
Q35927838 | Amplified RLR signaling activation through an interferon-stimulated gene-endoplasmic reticulum stress-mitochondrial calcium uniporter protein loop |
Q35936773 | Analysis of Transcriptional Signatures in Response to Listeria monocytogenes Infection Reveals Temporal Changes That Result from Type I Interferon Signaling |
Q40085222 | Anti-Cancer Drug HMBA Acts as an Adjuvant during Intracellular Bacterial Infections by Inducing Type I IFN through STING. |
Q38748641 | Antitumour actions of interferons: implications for cancer therapy |
Q28394994 | Antiviral regulation in porcine monocytic cells at different activation states |
Q34745565 | Apoptotic caspases prevent the induction of type I interferons by mitochondrial DNA. |
Q36492367 | Asthma exacerbations: a molecular dichotomy between antiviral and pro-inflammatory responses revealed |
Q40213573 | Autocrine activation of the IFN signaling pathway may promote immune escape in glioblastoma |
Q52371735 | Bacterial-Host Interactions: Physiology and Pathophysiology of Respiratory Infection. |
Q47555713 | Blimp-1/PRDM1 is a critical regulator of Type III Interferon responses in mammary epithelial cells |
Q41807293 | Blockade of chronic type I interferon signaling to control persistent LCMV infection |
Q92765898 | Bloom syndrome protein restrains innate immune sensing of micronuclei by cGAS |
Q39283180 | Bone Marrow-Derived Mesenchymal Stem Cells From Patients With Systemic Lupus Erythematosus Have a Senescence-Associated Secretory Phenotype Mediated by a Mitochondrial Antiviral Signaling Protein-Interferon-β Feedback Loop. |
Q34646554 | Borrelia burgdorferi arthritis-associated locus Bbaa1 regulates Lyme arthritis and K/B×N serum transfer arthritis through intrinsic control of type I IFN production |
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Q39128976 | Canonical and Non-Canonical Aspects of JAK-STAT Signaling: Lessons from Interferons for Cytokine Responses |
Q36451854 | Cardif (MAVS) Regulates the Maturation of NK Cells |
Q58091450 | Caspase-8 induces cleavage of gasdermin D to elicit pyroptosis during infection |
Q89000356 | Cell-intrinsic regulation of murine epidermal Langerhans cells by protein S |
Q36895423 | Changing partners at the dance: Variations in STAT concentrations for shaping cytokine function and immune responses to viral infections |
Q28487445 | Characterizing the relationship between steady state and response using analytical expressions for the steady states of mass action models |
Q54112529 | Compound heterozygous TYK2 mutations underlie primary immunodeficiency with T-cell lymphopenia. |
Q39241252 | Conditional IFNAR1 ablation reveals distinct requirements of Type I IFN signaling for NK cell maturation and tumor surveillance |
Q64937387 | Constitutive Interferon Maintains GBP Expression Required for Release of Bacterial Components Upstream of Pyroptosis and Anti-DNA Responses. |
Q47094073 | Constitutively elevated levels of SOCS1 suppress innate responses in DF-1 immortalised chicken fibroblast cells |
Q28602705 | Contraction of the type I IFN locus and unusual constitutive expression of IFN-α in bats |
Q36364287 | Control of the induction of type I interferon by Peste des petits ruminants virus |
Q35108235 | Critical role of interferon-α constitutively produced in human hepatocytes in response to RNA virus infection |
Q52648279 | Critical role of the endogenous interferon ligand-receptors in type I and type II interferons response. |
Q39260017 | Cross Talk between Inhibitory Immunoreceptor Tyrosine-Based Activation Motif-Signaling and Toll-Like Receptor Pathways in Macrophages and Dendritic Cells. |
Q40561368 | Cutting Edge: Direct Sensing of TLR7 Ligands and Type I IFN by the Common Myeloid Progenitor Promotes mTOR/PI3K-Dependent Emergency Myelopoiesis. |
Q30381154 | Cytokine Activation by Antibody Fragments Targeted to Cytokine-Receptor Signaling Complexes. |
Q50044861 | Cytosolic DNA Sensing Promotes Macrophage Transformation and Governs Myocardial Ischemic Injury. |
Q40107354 | DDX6 Represses Aberrant Activation of Interferon-Stimulated Genes |
Q53734706 | Deficiency in plasmacytoid dendritic cells and type I interferon signalling prevents diet-induced obesity and insulin resistance in mice. |
Q64899744 | Deficient pulmonary IFN-β expression in COPD patients. |
Q44657393 | Defined Sensing Mechanisms and Signaling Pathways Contribute to the Global Inflammatory Gene Expression Output Elicited by Ionizing Radiation. |
Q34651934 | Defining the transcriptional and cellular landscape of type 1 diabetes in the NOD mouse |
Q38997361 | Delayed apoptosis of tumor associated neutrophils in the absence of endogenous IFN-β. |
Q37358380 | Despite Increased Type 1 IFN, Autoimmune Nonobese Diabetic Mice Display Impaired Dendritic Cell Response to CpG and Decreased Nuclear Localization of IFN-Activated STAT1. |
Q41944558 | Different STAT Transcription Complexes Drive Early and Delayed Responses to Type I IFNs |
Q34615006 | Differential activity of type I interferon subtypes for dendritic cell differentiation |
Q40884254 | Distinct immunologic and radiographic patterns in etanercept-induced lung injury |
Q37565269 | Epidermal growth factor receptor inhibitors trigger a type I interferon response in human skin. |
Q38065485 | Epigenetic regulation of macrophage polarization and function |
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Q27469006 | Expansion of amphibian intronless interferons revises the paradigm for interferon evolution and functional diversity |
Q39253678 | Fas-Associated Factor 1 Negatively Regulates the Antiviral Immune Response by Inhibiting Translocation of Interferon Regulatory Factor 3 to the Nucleus |
Q38591382 | Fine-tuning of type I IFN-signaling in microglia--implications for homeostasis, CNS autoimmunity and interferonopathies |
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Q37598937 | GAS6 is a key homeostatic immunological regulator of host-commensal interactions in the oral mucosa. |
Q35088187 | Genome-wide analysis of antiviral signature genes in porcine macrophages at different activation statuses |
Q38775242 | Growing tumors induce a local STING dependent Type I IFN response in dendritic cells |
Q93335194 | HDAC stimulates gene expression through BRD4 availability in response to IFN and in interferonopathies |
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Q38486383 | IFNA2: The prototypic human alpha interferon. |
Q36509839 | IFNAR signaling directly modulates T lymphocyte activity, resulting in milder experimental autoimmune encephalomyelitis development |
Q36525884 | IFNα gene/cell therapy curbs colorectal cancer colonization of the liver by acting on the hepatic microenvironment |
Q64971795 | IRF1 Maintains Optimal Constitutive Expression of Antiviral Genes and Regulates the Early Antiviral Response. |
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Q39077769 | Identification of a negative feedback loop between cyclic di-GMP-induced levels of IFI16 and p202 cytosolic DNA sensors and STING. |
Q34712064 | Identification of residues of SARS-CoV nsp1 that differentially affect inhibition of gene expression and antiviral signaling |
Q35145346 | Inherited STING-activating mutation underlies a familial inflammatory syndrome with lupus-like manifestations |
Q38973834 | Interaction of SARS and MERS Coronaviruses with the Antiviral Interferon Response. |
Q36127624 | Interferon Tau Affects Mouse Intestinal Microbiota and Expression of IL-17. |
Q91345396 | Interferon target-gene expression and epigenomic signatures in health and disease |
Q26861003 | Interferon-alpha, immune activation and immune dysfunction in treated HIV infection |
Q37259195 | Interferon-dependent IL-10 production by Tregs limits tumor Th17 inflammation |
Q92860608 | Interferon-inducible cytoplasmic lncLrrc55-AS promotes antiviral innate responses by strengthening IRF3 phosphorylation |
Q34653726 | Interferon-tau attenuates uptake of nanoparticles and secretion of interleukin-1β in macrophages |
Q33988567 | Interferons and their stimulated genes in the tumor microenvironment |
Q89533105 | Intestinal epithelial cells express immunomodulatory ISG15 during active ulcerative colitis and Crohn's disease |
Q52650219 | Intracellular Antiviral Immunity. |
Q36813754 | Late stages of T cell maturation in the thymus involve NF-κB and tonic type I interferon signaling |
Q28602250 | Leucocyte subset-specific type 1 interferon signatures in SLE and other immune-mediated diseases |
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Q37571293 | Novel antiviral host factor, TNK1, regulates IFN signaling through serine phosphorylation of STAT1. |
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