Biochemical and Proteomic Analysis of Ubiquitination of Hsc70 and Hsp70 by the E3 Ligase CHIP

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Biochemical and Proteomic Analysis of Ubiquitination of Hsc70 and Hsp70 by the E3 Ligase CHIP is …
instance of (P31):
scholarly articleQ13442814

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P819ADS bibcode2015PLoSO..1028240S
P356DOI10.1371/JOURNAL.PONE.0128240
P3181OpenCitations bibliographic resource ID3151498
P932PMC publication ID4444009
P698PubMed publication ID26010904
P5875ResearchGate publication ID277962519

P2093author name stringWalter J Chazin
Kristie L Rose
Salisha Hill
Sarah E Soss
Sophie Jouan
P2860cites workInsights into the conformational dynamics of the E3 ubiquitin ligase CHIP in complex with chaperones and E2 enzymes.Q51560326
Allosteric regulation of Hsp70 chaperones involves a conserved interdomain linkerQ79278307
Identification of CHIP, a novel tetratricopeptide repeat-containing protein that interacts with heat shock proteins and negatively regulates chaperone functionsQ22010047
The co-chaperone CHIP regulates protein triage decisions mediated by heat-shock proteinsQ24290709
The ubiquitin-conjugating enzyme (E2) Ube2w ubiquitinates the N terminus of substratesQ24605908
Solution conformation of wild-type E. coli Hsp70 (DnaK) chaperone complexed with ADP and substrateQ27655465
Molecular architecture and assembly of the eukaryotic proteasomeQ27693890
The SWISS-MODEL workspace: a web-based environment for protein structure homology modellingQ27860637
The ubiquitin systemQ27860803
An approach to correlate tandem mass spectral data of peptides with amino acid sequences in a protein databaseQ27861106
CHIP is a U-box-dependent E3 ubiquitin ligase: identification of Hsc70 as a target for ubiquitylationQ28216253
CHIP-mediated stress recovery by sequential ubiquitination of substrates and Hsp70Q28303344
Mms2-Ubc13 covalently bound to ubiquitin reveals the structural basis of linkage-specific polyubiquitin chain formationQ29619698
Identification of residues on Hsp70 and Hsp90 ubiquitinated by the cochaperone CHIPQ34048681
The function of heat-shock proteins in stress tolerance: degradation and reactivation of damaged proteinsQ34336799
Ube2W conjugates ubiquitin to α-amino groups of protein N-terminiQ34337452
The ABC's (and XYZ's) of peptide sequencingQ34344848
Certain pairs of ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s) synthesize nondegradable forked ubiquitin chains containing all possible isopeptide linkages.Q34617875
Ubiquitin in motion: structural studies of the ubiquitin-conjugating enzyme∼ubiquitin conjugateQ34666396
E2 conjugating enzyme selectivity and requirements for function of the E3 ubiquitin ligase CHIP.Q35065158
Imbalance of Hsp70 family variants fosters tau accumulationQ36710912
Dynamic interactions of proteins in complex networks: identifying the complete set of interacting E2s for functional investigation of E3-dependent protein ubiquitinationQ37588018
100% protein sequence coverage: a modern form of surrealism in proteomicsQ37772117
The complexity of recognition of ubiquitinated substrates by the 26S proteasomeQ38122985
CHIP is a chaperone-dependent E3 ligase that ubiquitylates unfolded proteinQ41776375
The E3 ubiquitin ligase CHIP and the molecular chaperone Hsc70 form a dynamic, tethered complexQ42833100
The size of the proteasomal substrate determines whether its degradation will be mediated by mono- or polyubiquitylationQ46223379
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue5
P407language of work or nameEnglishQ1860
P921main subjectprotein ubiquitinationQ3547638
P304page(s)e0128240
P577publication date2015-01-01
P1433published inPLOS OneQ564954
P1476titleBiochemical and Proteomic Analysis of Ubiquitination of Hsc70 and Hsp70 by the E3 Ligase CHIP
P478volume10

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cites work (P2860)
Q28078724A Decade of Boon or Burden: What Has the CHIP Ever Done for Cellular Protein Quality Control Mechanism Implicated in Neurodegeneration and Aging?
Q39842950A Drosophila heat shock response represents an exception rather than a rule amongst Diptera species
Q48227312Interplay between recombinant Hsp70 and proteasomes: proteasome activity modulation and ubiquitin-independent cleavage of Hsp70.
Q33788240Lys48 ubiquitination during the intraerythrocytic cycle of the rodent malaria parasite, Plasmodium chabaudi
Q44917386Multi-omics Comparative Analysis Reveals Multiple Layers of Host Signaling Pathway Regulation by the Gut Microbiota
Q26771978RNA-Binding Proteins in Trichomonas vaginalis: Atypical Multifunctional Proteins
Q39430414Repair or destruction-an intimate liaison between ubiquitin ligases and molecular chaperones in proteostasis
Q47141859Small Molecule Enhancement of 20S Proteasome Activity Targets Intrinsically Disordered Proteins
Q58766271UBXN2A enhances CHIP-mediated proteasomal degradation of oncoprotein mortalin-2 in cancer cells

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