Tachykinin receptors and tachykinin receptor antagonists

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Tachykinin receptors and tachykinin receptor antagonists is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1111/J.1474-8673.1993.TB00396.X
P3181OpenCitations bibliographic resource ID5090579
P698PubMed publication ID8382703

P2093author name stringA Giachetti
C A Maggi
R Patacchini
P Rovero
P2860cites workNeurotrophic and neurotoxic effects of amyloid beta protein: reversal by tachykinin neuropeptidesQ22242269
Human substance P receptor (NK-1): organization of the gene, chromosome localization, and functional expression of cDNA clonesQ24311743
An unidentified depressor substance in certain tissue extractsQ24540414
Molecular characterisation, expression and localisation of human neurokinin‐3 receptorQ28209225
Isolation and characterisation of the human lung NK-2 receptor gene using rapid amplification of cDNA endsQ28274008
Molecular cloning, structural characterization and functional expression of the human substance P receptorQ28279939
NK2 tachykinin receptors and contraction of circular muscle of the human colon: characterization of the NK2 receptor subtypeQ28283883
Isolation and characterisation of the human lung NK-1 receptor cDNAQ28305731
Antagonists for the neurokinin NK-3 receptor evaluated in selective receptor systemsQ28330800
Different receptors are involved in the endothelium-mediated relaxation and the smooth muscle contraction of the rabbit pulmonary artery in response to substance P and related neurokininsQ28337015
Stable expression of high affinity NK1 (substance P) and NK2 (neurokinin A) receptors but low affinity NK3 (neurokinin B) receptors in transfected CHO cellsQ28343055
Preprotachykinin gene expression in the human basal ganglia: characterization of mRNAs and pre-mRNAs produced by alternate RNA splicingQ31160220
Further evidence for the existence of NK2 tachykinin receptor subtypesQ33241565
Actinomycin D is a competitive and selective antagonist at NK2 tachykinin receptorsQ33241794
Alterations in cat knee joint blood flow induced by electrical stimulation of articular afferents and efferentsQ33262404
The non‐peptide NK1 receptor antagonist, (±)‐CP‐96,345, produces antinociceptive and anti‐oedema effects in the ratQ42238959
Tachykinin receptors in the guinea-pig renal pelvis: activation by exogenous and endogenous tachykininsQ42278083
Clinical and inflammatory responses to exogenous tachykinins in allergic rhinitisQ42467148
Tachykinin receptors in the circular muscle of the guinea-pig ileumQ42562051
Investigation into species variants in tachykinin NK1 receptors by use of the non-peptide antagonist, CP-96,345Q42710885
Stimulation of connective tissue cell growth by substance P and substance K.Q42815612
Comparison of the effects of epithelium removal and of an enkephalinase inhibitor on the neurokinin-induced contractions of guinea-pig isolated tracheaQ42848928
Regulation of epithelial transport in the jejunal mucosa of the guinea pig by neurokininsQ43463625
Substance P-like immunoreactivity in adrenal chromaffin cells and intra-adrenal nerve fibers of ratsQ43486931
Multiple tachykinins (neurokinin A, neuropeptide K and substance P) in capsaicin-sensitive sensory neurons in the guinea-pigQ43516687
Effects of actinomycin D on airway constriction induced by tachykinins and capsaicin in guinea-pigsQ43518101
Tachykinin receptors and noncholinergic bronchoconstriction in the guinea-pig isolated bronchiQ43534445
Neurokinins produce selective venoconstriction via NK-3 receptors in the rat mesenteric vascular bed.Q43678529
Tachykinins and calcitonin gene-related peptide as co-transmitters in local motor responses produced by sensory nerve activation in the guinea-pig isolated renal pelvis.Q43780079
Pupillary supersensitivity to substance P following prolonged treatment with tetrodotoxin or substance P antagonistsQ43841333
Further studies on the motor response of the human isolated urinary bladder to tachykinins, capsaicin and electrical field stimulationQ43862254
Substance P-, calcitonin gene-related peptide-and C-flanking peptide of neuropeptide Y-immunoreactive fibres are present in normal synovium but depleted in patients with rheumatoid arthritisQ43925730
Effect of substance P/bombesin antagonists on the release of growth hormone by GHRP and GHRHQ43948451
Substance P release from knee joint afferent terminals: modulation by opioidsQ44030680
Heterogeneity of tachykinin-like immunoreactive peptides in rat spinal cord and dorsal root gangliaQ44091468
Tachykinin multiplicity in rat central nervous system as studied using antisera raised against substance P and neurokinin A.Q44185914
Regional distribution of neuropeptide γ and other tachykinin peptides derived from the substance P gene in the ratQ44215164
Evidence for substance P as a functional neurotransmitter in guinea pig small intestinal mucosaQ44288635
Motor response of the human isolated colon to capsaicin and its relationship to release of vasoactive intestinal polypeptide.Q44497126
Tachykinin antagonists inhibit the morphine withdrawal response in guinea-pigsQ44500639
Dactinomycin is a competitive neurokinin-2 receptor antagonistQ44509636
The effects of capsaicin upon electrogenic ion transport in rat descending colonQ44518259
Substance P enhances interferon-gamma production by human peripheral blood mononuclear cellsQ44625214
In vivo pharmacology of [beta Ala8]neurokinin A-(4-10), a selective NK-2 tachykinin receptor agonistQ44787444
Human isolated small intestine: motor responses of the longitudinal muscle to field stimulation and exogenous neuropeptidesQ44951761
Presence of various carbohydrate moieties including beta-galactose and N-acetylglucosamine residues on solubilized porcine brain neurokinin-1/substance P receptorsQ45202013
Effects of substance P and neurokinin A (substance K) on motor behavior: unique effect of substance P attributable to its amino-terminal sequenceQ45230937
Role of central tachykinin peptides in cardiovascular regulation in ratsQ45238582
Stereospecific effects of a nonpeptidic NK1 selective antagonist, CP-96,345: Antinociception in the absence of motor dysfunctionQ46008800
Effect of endothelium on the actions of sympathetic and sensory nerves in the perfused rat mesenteryQ46128636
Substance P antagonists showing some selectivity for different receptor typesQ46143344
Structure-activity studies of heptapeptide derivatives related to substance P, neurokinin A, B and other tachykinins on smooth musclesQ46175012
A synthetic peptide that is a bombesin receptor antagonistQ46175289
Activity of peptide and non-peptide antagonists at peripheral NK1 receptorsQ46185121
Release of multiple tachykinins from capsaicin-sensitive sensory nerves in the lung by bradykinin, histamine, dimethylphenyl piperazinium, and vagal nerve stimulationQ46256671
Substance P enteric neurons mediate non-cholinergic transmission to the circular muscle of the guinea-pig intestineQ46357246
A specific substance P antagonist blocks smooth muscle contractions induced by non-cholinergic, non-adrenergic nerve stimulationQ46380348
In vivo and in vitro actions of mammalian tachykininsQ46532142
Multiple tachykinin binding sites in hamster, rat and guinea-pig urinary bladderQ46558511
Use of substance P fragments to differentiate substance P receptors of different tissuesQ46570554
Neurokinin receptors antagonists: old and new.Q46588584
Intestinal peristalsis associated with release of immunoreactive substance PQ46598921
Multiple tachykinin binding sites in peripheral tissues and in brainQ46609145
Effects of selective tachykinin receptor antagonists on capsaicin- and tachykinin-induced bronchospasm in anaesthetized guinea-pigsQ46628082
Structure-activity studies of neurokinin A.Q46686837
Capillary permeability induced by intravenous neurokinins. Receptor characterization and mechanism of action.Q50886925
Capsaicin induced release of multiple tachykinins (substance P, neurokinin A and eledoisin-like material) from guinea-pig spinal cord and ureter.Q50907967
Plasma extravasation in the cat knee-joint induced by antidromic articular nerve stimulation.Q50916209
Comparison of cardiovascular and bronchoconstrictor effects of substance P, substance K and other tachykininsQ50919872
Substance P-Evoked release of GABA from isolated spinal cord of the newborn ratQ51721713
Mediators of substance P-induced inflammation in the rat knee jointQ51725469
Evidence for an involvement of substance P, but not cholecystokinin-like peptides, in hexamethonium-resistant intestinal peristalsis.Q51762780
Bronchoconstrictor and hypotensive effects in relation to pharmacokinetics of tachykinins in the guinea-pig--evidence for extraneuronal cleavage of neuropeptide K to neurokinin A.Q51787780
Extravasation in the knee induced by antidromic stimulation of articular C fibre afferents of the anaesthetized cat.Q51803208
Comparison of the effects of substance P and substance K on blood pressure, salivation and urinary bladder motility in urethane-anaesthetized rats.Q51824548
Evidence for the involvement of endogenous substance P in the motor effects of capsaicin on the rat urinary bladder.Q51830587
Undeca- and octa-peptide antagonists for substance P, a study on the guinea pig trachea.Q51847574
Ocular responses evoked by capsaicin and prostaglandin E2 are inhibited by a substance P antagonistQ51851683
On the role of NK-2 tachykinin receptors in the mediation of spinal reflex excitability in the rat.Q52239152
Ultrastructural localisation of serotonin and substance P in vascular endothelial cells of rat femoral and mesenteric arteries.Q52254068
Neurokinin A (NK2) receptor revisited with SR 48968, a potent non-peptide antagonistQ53845785
Selective agonists of NK-2 binding sites highly active on rat portal vein (NK-3 bioassay)Q53859757
Tachykinin receptors in the guinea-pig isolated bronchi.Q53859914
Comparison of the presence and actions of substance P and neurokinin A in guinea-pig taenia coli.Q53860653
Phylogeny of tachykinin receptor localization in the vertebrate central nervous system: apparent absence of neurokinin-2 and neurokinin-3 binding sites in the human brainQ53863667
Activity and Distribution of Binding Sites in Brain of a Nonpeptide Substance P (NK 1 ) Receptor AntagonistQ53863671
Substance P-immunoreactive sensory nerves in the lower respiratory tract of various mammals including manQ53917173
Influence of perivascular peptides on endoneurial blood flow and microvascular resistance in the sciatic nerve of the ratQ54284273
In vitro effects of substance P on neonatal rat sympathetic preganglionic neurones.Q54385053
The possible existence of multiple receptors for substance PQ55062375
Substance P and neurokinin A are codistributed and colocalized in the porcine gastrointestinal tractQ58449288
Fertilization of Denuded Rabbit Eggs in vitro by Sperm recovered from the Uterus or VaginaQ59067575
Receptor binding sites for substance P, but not substance K or neuromedin K, are expressed in high concentrations by arterioles, venules, and lymph nodules in surgical specimens obtained from patients with ulcerative colitis and Crohn diseaseQ33571955
Neuropeptide K potently stimulates salivary gland secretion and potentiates substance P-induced salivationQ33830293
Molecular characterization of a functional cDNA encoding the rat substance P receptorQ33891305
Competitive antagonists discriminate between NK2 tachykinin receptor subtypesQ33933966
Substance P receptor binding sites are expressed by glia in vivo after neuronal injuryQ34288573
Asthma as an axon reflexQ34382020
Three rat preprotachykinin mRNAs encode the neuropeptides substance P and neurokinin AQ34594580
Role of NK1 tachykinin receptors in thermonociception: Effect of (±)-CP 96,345, a non-peptide substance P antagonist, on the hot plate test in miceQ34599054
Depolarizing influences regulate preprotachykinin mRNA in sympathetic neuronsQ34641526
Vasoconstrictor effects in spinal cord of the substance P antagonist [D-Arg, D-Trp7,9 Leu11]-substance P (Spantide) and somatostatin and interaction with thyrotropin releasing hormoneQ35118849
Therapeutic potential of capsaicin-like molecules: studies in animals and humansQ35528847
Intragastric capsaicin enhances rat gastric acid elimination and mucosal blood flow by afferent nerve stimulationQ35756165
Effects of capsaicin pretreatment on neuropeptides and salivary secretion of rat parotid glandsQ35756650
NK-1 receptor mediation of neurogenic plasma extravasation in rat skinQ35756691
Tachykinin antagonists and capsaicin-induced contraction of the rat isolated urinary bladder: evidence for tachykinin-mediated cotransmissionQ35871938
The non-peptide tachykinin antagonist, CP-96,345, is a potent inhibitor of neurogenic inflammationQ35872152
Inhibition of neurogenic plasma exudation in guinea-pig airways by CP-96,345, a new non-peptide NK1 receptor antagonistQ35872417
A tachykinin antagonist inhibits gastric emptying and gastrointestinal transit in the rat.Q35887462
Substance P in sensory nerve fibres contributes to the development of oedema in the rat hind paw after thermal injuryQ36004414
cDNA cloning of bovine substance-K receptor through oocyte expression system.Q36288721
NK-2 receptor agonists and antagonistsQ36440037
Pain and neurotransmittersQ36609561
Concepts in Characterization of Tachykinin ReceptorsQ36697019
Substance P interactions with the nicotinic response.Q36697074
The Tachykinin Neuroimmune Connection in Inflammatory PainQ36697090
Substance P and neurodegenerative disorders. A speculative reviewQ36716659
Structure and gene organization of bovine neuromedin K precursorQ37400075
Characterization of a tachykinin peptide NK2 receptor transfected into murine fibroblast B82 cellsQ37412709
Precursor forms of substance P (SP) in nervous tissue: detection with antisera to SP, SP-Gly, and SP-Gly-LysQ37541699
Neurokinin B is a preferred agonist for a neuronal substance P receptor and its action is antagonized by enkephalinQ37554258
Effect of CP-96,345, a nonpeptide substance P receptor antagonist, on salivation in ratsQ37617969
Pharmacological properties of a potent and selective nonpeptide substance P antagonistQ37621800
Neuroeffector functions of sensory fibres: implications for headache mechanisms and drug actionsQ37748431
Substance P and Arg-Pro-Lys-Pro-NH-C12-H25-induced mediator release from different mast cell subtypes of rat and guinea-pigQ46694592
Autoradiographic mapping of substance P receptors in lungQ46711911
Activity of spantide I and II at various tachykinin receptors and NK-2 tachykinin receptor subtypesQ46713541
Release of substance P- and substance K-like immunoreactivities from the isolated perfused guinea-pig lungQ46766188
Multiple tachykinin receptors in guinea pig brain. High densities of substance K (neurokinin A) binding sites in the substantia nigraQ46796361
Interaction of amyloid beta protein (25-35) with tachykinin receptorsQ46829086
Imidazo[4,5-b]quinoxaline cyanines as neurokinin antagonistsQ46863056
[Leu9 psi(CH2NH)Leu10]-neurokinin A (4-10) (MDL 28,564) distinguishes tissue tachykinin peptide NK2 receptorsQ46873316
Potent and highly selective neurokinin antagonistsQ46886862
Conversion of neuropeptide K to neurokinin A and vesicular colocalization of neurokinin A and substance P in neurons of the guinea pig small intestineQ46925262
Species differences in affinities of non-peptide antagonists for substance p receptorsQ46925772
Release of immunoreactive substance P in the spinal cord during development of acute arthritis in the knee joint of the cat: a study with antibody microprobesQ47575135
Substance P levels differ in sympathetic target organ terminals and ganglion perikaryaQ47734893
Localization of tachykinin binding sites (NK1, NK2, NK3 ligands) in the rat brainQ48108880
Neuropeptides and their peptidases: Functional considerationsQ48124573
The NK-3 tachykinin agonist senktide elicits yawning and chewing mouth movements following subcutaneous administration in the rat. Evidence for cholinergic mediation.Q48167486
Regional distribution of neuropeptide K and other tachykinins (neurokinin A, neurokinin B and substance P) in rat central nervous systemQ48265472
Pharmacologic characterization and autoradiographic distribution of binding sites for iodinated tachykinins in the rat central nervous systemQ48283640
Substance P antagonists in substantia nigra are anticonvulsantQ48299053
Behavioural effects of tachykinins and related peptidesQ48309587
In vivo release of substance P in the nucleus tractus solitarii increases during hypoxiaQ48310888
Tissue-specific generation of two preprotachykinin mRNAs from one gene by alternative RNA splicingQ48384593
Selective activation of mesolimbic and mesocortical dopamine metabolism in rat brain by infusion of a stable substance P analogue into the ventral tegmental areaQ48386085
Nucleotide sequences of cloned cDNAs for two types of bovine brain substance P precursorQ48395090
Regional distribution of substance P, neurokinin alpha and neurokinin beta in rat spinal cord, nerve roots and dorsal root ganglia, and the effects of dorsal root section or spinal transectionQ48427028
Calcium-dependent potassium-stimulated release of neurokinin A and neurokinin B from rat brain regions in vitroQ48459178
Substance K excites dopaminergic and non-dopaminergic neurons in rat substantia nigraQ48480241
The substance P receptor subtype modulating catecholamine release from adrenal chromaffin cellsQ48496330
Distribution of neurons expressing neurokinin B in the rat brain: immunohistochemistry and in situ hybridizationQ48506705
Neurokinin agonists differentially affect A9 and A10 dopamine cells in the rat.Q48507580
Regional distribution and in vivo release of tachykinin-like immunoreactivities in rat brain: evidence for regional differences in relative proportions of tachykininsQ48519093
Characterization of substance P-like immunoreactivity and tachykinin-encoding mRNAs in rat medullary thyroid carcinoma cell linesQ48521722
Evidence that substance P and somatostatin transmit separate information related to pain in the spinal dorsal hornQ48534576
Substance K and substance P differentially modulate mesolimbic and mesocortical systemsQ48587478
Regional distribution of substance P, neurokinin α and neurokinin β in rat central nervous systemQ48599826
Novel Pharmacology of Substance K-Binding Sites: a Third Type of Tachykinin ReceptorQ48600937
Biochemical characterization and anatomical distribution of a major form of unamidated precursor of substance P in rat brainQ48608355
Binding sites for [3H][Sar9, Met(O2)11]substance P in rat bain and guinea pig ileumQ48653617
Substance P in the rat parotid gland: evidence for a dual origin from the otic and trigeminal gangliaQ48656091
Role of D-tryptophan for affinity of MEN 10207 tachykinin antagonist at NK2 receptorsQ48668004
Species differences between [3h] substance P binding in rat and guinea-pig shown by the use of peptide agonists and antagonistsQ48670130
Injection of tachykinins and selective neurokinin receptor ligands into the substantia nigra reticulata increases striatal dopamine and 5-hydroxytryptamine metabolismQ48768042
Role of NK-2 receptors in the antidipsogenic activity of neurokinins in the mouseQ48847320
Localization of neuropeptide receptor mRNA in rat brain: Initial observations using probes for neurotensin and substance P receptorsQ48857796
Binding characteristics of [125I]Bolton-Hunter [Sar9,Met(O2)11]substance P, a new selective radioligand for the NK1 receptorQ48920304
[125I]-Bolton-Hunter scyliorhinin II: a novel, selective radioligand for the tachykinin NK3 receptor in rat brainQ48943621
Inhibition of salt appetite in the rat following injection of tachykinins into the medial amygdalaQ49022500
NK-1, but not NK-2, tachykinin receptors mediate plasma extravasation induced by antidromic C-fiber stimulation in rat hindpaw: Demonstrated with the NK-1 antagonist CP-96,345 and the NK-2 antagonist Men 10207Q50793165
Direct evidence that capsaicin-induced plasma protein extravasation is mediated through tachykinin NK1 receptorsQ50798603
Cigarette smoke-induced airway oedema is blocked by the NK1 antagonist, CP-96,345Q50800418
Tachykinin receptor types: Classification and membrane signalling mechanismsQ37760972
G protein activation: a receptor-independent mode of action for cationic amphiphilic neuropeptides and venom peptides.Q37827766
Tachykinin receptors in the airways and lung: what should be block?Q37903173
Interactions between neuropeptides and dopamine neurons in the ventromedial mesencephalonQ38156461
"Kassinin" in mammals: the newest tachykininsQ38161330
Search for a physiological role of substance P in gastrointestinal motilityQ38163187
Pharmacological receptors for substance P and neurokininsQ38170054
Arthritis and the nervous systemQ38201398
New selective agonists for neurokinin receptors: pharmacological tools for receptor characterizationQ39332972
The sensory-efferent function of capsaicin-sensitive sensory neuronsQ39631475
Local effector functions of capsaicin-sensitive sensory nerve endings: involvement of tachykinins, calcitonin gene-related peptide and other neuropeptidesQ39645839
Substance P and multiple sclerosisQ41092137
The involvement of neurokinin receptor subtypes in somatosensory processing in the superficial dorsal horn of the cat.Q41137377
Tachykinin-mediated modulation of the primary antibody response in rats: evidence for mediation by an NK-2 receptorQ41138481
Tachykinin-like immunoreactivity in the mammalian urinary bladder: correlation with the functions of the capsaicin-sensitive sensory nervesQ41253919
Spinal action of neurokinins producing cardiovascular responses in the conscious freely moving rat: evidence for a NK-1 receptor mechanismQ41256172
Isolation and characterization of neurokinin A, neurokinin A(3-10) and neurokinin A(4-10) from a neutral water extract of a metastatic ileal carcinoid tumourQ41372294
Demonstration of a neurokinin A receptor subtype in transfected fibroblastsQ41640120
Evidence of NK1 and NK2 tachykinin receptors and their involvement in histamine release in a murine mast cell lineQ41642073
Multiple NK2 receptor subtypes are suggested by physiological and biochemical studies with neurokinin A (NKA) analogues and antagonistsQ41708952
[D-Arg1,D-Phe5,D-Trp7,9,Leu11]substance P, a neuropeptide antagonist, blocks binding, Ca2(+)-mobilizing, and mitogenic effects of endothelin and vasoactive intestinal contractor in mouse 3T3 cells.Q41720904
Substance P stimulates neovascularization in vivo and proliferation of cultured endothelial cellsQ41724135
Biological evaluation of substance P antagonistsQ41741345
A study of [d-Pro2, d-Phe7, d-Trp9]-substance P and [d-Trp7,9]-substance P as tachykinin partial agonists in the rat colonQ41742767
Different substance P receptors are found on mucosal epithelial cells and submucous neurons of the guinea-pig small intestine.Q41768394
Selective localization of vasoactive intestinal peptide and substance P in human eosinophilsQ41784502
Tachykinins activate guinea-pig alveolar macrophages: involvement of NK2 and NK1 receptorsQ41811618
Novel selective agonists and antagonists confirm neurokinin NK1 receptors in guinea-pig vas deferensQ41823272
Characterization of histamine-H3 receptors controlling non-adrenergic non-cholinergic contractions of the guinea-pig isolated ileumQ41843309
Tachykinin receptors in smooth muscles: a study with agonists (substance P, neurokinin A) and antagonists.Q41856571
NK1-receptors mediate the proliferative response of human fibroblasts to tachykininsQ41861649
Differences in neurokinin receptor pharmacology between rat and guinea-pig superior cervical gangliaQ41864232
Tachykinin NK1 receptor in the guinea-pig isolated proximal urethra: characterization by receptor selective agonists and antagonistsQ41885307
Characterization of the receptor mediating relaxation to substance P in canine middle cerebral artery: no evidence for involvement of substance P in neurogenically mediated relaxationQ41943134
Sensory nerves, vascular endothelium and neurogenic relaxation of the guinea-pig isolated pulmonary arteryQ41983251
Receptors mediating tachykinin-induced contractile responses in guinea-pig tracheaQ41984021
The mechanism of action of a substance P antagonist (D-Pro2, D-Trp7,9)-SP.Q41984028
An examination of the pharmacology of two substance P antagonists and the evidence for tachykinin receptor subtypesQ41985800
Effect of 5-HT3 receptor antagonists on responses to selective activation of mesolimbic dopaminergic pathways in the ratQ41990391
Bronchodilatation by tachykinins and capsaicin in the mouse main bronchusQ42020312
Intramural neurons of the guinea-pig urinary bladder: histochemical localization of putative neurotransmitters in cultures and newborn animalsQ42030998
Modulation of the vasodepressor actions of acetylcholine, bradykinin, substance P and endothelin in the rat by a specific inhibitor of nitric oxide formationQ42051498
Stimulatory effect of substance P on sympathetic ganglia and spinal cord in cultureQ42098468
Tachykininergic transmission to the circular muscle of the guinea-pig ileum: evidence for the involvement of NK2 receptorsQ42106654
Substance P is released from the endothelium of normal and capsaicin-treated rat hind-limb vasculature, in vivo, by increased flowQ42130399
Tachykinin antagonists have potent local anaesthetic actionsQ42148905
Vasoactive intestinal peptide in bovine pulmonary artery: localisation, function and receptor autoradiographyQ42197644
Sialic acid is selectively involved in the interaction of agonists with M2 muscarinic acetylcholine receptorsQ42213248
P433issue1
P407language of work or nameEnglishQ1860
P921main subjecttachykinin receptorQ426034
P304page(s)23-93
P577publication date1993-02-01
P1433published inAutonomic and Autacoid PharmacologyQ15754246
P1476titleTachykinin receptors and tachykinin receptor antagonists
P478volume13

Reverse relations

cites work (P2860)
Q28368884'Sensory-efferent' neural control of mucus secretion: characterization using tachykinin receptor antagonists in ferret trachea in vitro
Q339779643-benzhydryl-4-piperidones as novel neurokinin-1 receptor antagonists and their efficient synthesis
Q43692536A flexible approach to the design of new potent substance P receptor ligands
Q47728062A method to measure dual NK1/NK2-antagonist activity in dogs
Q77744497A novel super-potent neurokinin A receptor antagonist containing dehydroalanine
Q44297334A tachykinin-like factor increases glutamate toxicity in rat cerebellar granule cells.
Q46701237AMPA receptors are modulated by tachykinins in rat cerebellum neurons
Q71237568Absorption of Cam-2445, and NK1 neurokinin receptor antagonist: in vivo, in situ, and in vitro evaluations
Q35040768Activation of the cloned human NK3 receptor in Chinese Hamster Ovary cells characterized by the cellular acidification response using the Cytosensor microphysiometer
Q41143394Alterations in neurokinin 1 receptor gene expression in models of pain and inflammation
Q24322842Altered nociception, analgesia and aggression in mice lacking the receptor for substance P
Q77153157An investigation of tachykinin NK2 receptor subtypes in the rat
Q43967464Analogs of Substance P modified at the C-terminus which are both agonist and antagonist of the NK-1 receptor depending on the second messenger pathway.
Q36621139Anti-tumour activity of tachykinin NK1 receptor antagonists on human glioma U373 MG xenograft
Q37039597Antiemetics: an update and the MASCC guidelines applied in clinical practice
Q44239828Application of LC-NMR for the study of the volatile metabolite of MK-0869, a substance P receptor antagonist
Q24676229Association between kinin B(1) receptor expression and leukocyte trafficking across mouse mesenteric postcapillary venules
Q48085106Autonomic & Autacoid Pharmacology: past, present and future
Q46610523Autoradiographic mapping of pulmonary NK1 and NK2 tachykinin receptors and changes after repeated antigen challenge in guinea pigs
Q44512655Biologic activity of the tachykinins on lamb and sheep gallbladder
Q58234708Building a model of interaction at the NK-2 receptors: Polycondensed heterocycles containing the pyrimidoindole skeleton
Q42097975Cardiovascular and behavioural effects of centrally administered neuropeptide K in the rat: receptor characterization
Q24679394Cardiovascular and behavioural effects of centrally administered tachykinins in the rat: characterization of receptors with selective antagonists
Q51420898Cellular and synaptic effect of substance P on neonatal phrenic motoneurons.
Q73153568Cellular localization and distribution of neurokinin-1 receptors in the rat stomach
Q46686742Cellular sites of expression of the neurokinin‐1 receptor in the rat gastrointestinal tract
Q73978655Central and peripheral antiulcer and antisecretory effects of Ala5NKA(4-10), a tachykinin NK2 receptor agonist, in rats
Q35026070Central antitussive activity of the NK1 and NK2 tachykinin receptor antagonists, CP-99,994 and SR 48968, in the guinea-pig and cat.
Q46150974Characterisation of substance P-induced endocytosis of NK1 receptors on enteric neurons
Q42063978Characterization of NK1 and NK2 tachykinin receptors in guinea-pig and rat bronchopulmonary and vascular systems
Q48493896Characterization of actions of Leucophaea tachykinin-related peptides (LemTRPs) and proctolin on cockroach hindgut contractions
Q41821983Characterization of central and peripheral effects of septide with the use of five tachykinin NK1 receptor antagonists in the rat.
Q43179592Characterization of receptors mediating contraction induced by tachykinins in the guinea-pig isolated common bile duct
Q52075495Characterization of substance P-membrane interaction by transferred nuclear Overhauser effect.
Q73031669Characterization of tachykinin NK2 receptor on dog proximal colon. Antagonism by MEN 10,627 and SR 48,968
Q35027108Characterization of tachykinin receptors in the uterus of the oestrogen-primed rat.
Q36826373Characterization of tachykinin receptors mediating plasma extravasation and vasodilatation in normal and acutely inflamed knee joints of the rat
Q35029104Characterization of the [125I]-neurokinin A binding site in the circular muscle of human colon
Q73862905Co-distribution of NK2 tachykinin receptors and substance P in nerve endings of guinea-pig ileum
Q46670511Combined tachykinin receptor antagonist: synthesis and stereochemical structure-activity relationships of novel morpholine analogues
Q41872098Comparative behavioural profile of centrally administered tachykinin NK1, NK2 and NK3 receptor agonists in the guinea-pig
Q46967061Comparative effects of nonpeptide tachykinin receptor antagonists on experimental gut inflammation in rats and guinea-pigs
Q38336515Comparative, general pharmacology of SDZ NKT 343, a novel, selective NK1 receptor antagonist.
Q42117930Comparison of tachykinin NK1 and NK2 receptors in the circular muscle of the guinea-pig ileum and proximal colon.
Q43680602Conformation of the tripeptide Cbz-Pro-Leu-Trp-OBzl(CF3)2 deduced from two-dimensional 1H-NMR and conformational energy calculations is related to its affinity for NK1-receptor.
Q77748933Conformational probes for elucidating the nature of substance P binding to the NK1 receptor: initial efforts to map the Phe7-Phe8 region
Q41508037Conserved HisVI-17 of the NK-1 receptor is involved in binding of non-peptide antagonists but not substance P.
Q44604761Contribution of tachykinin receptor subtypes to micturition reflex in guinea pigs
Q35623447Correlation between the appearance of neuropeptides in the rat trigeminal ganglion and reinnervation of the healing root socket after tooth extraction
Q36568728Current and emerging investigational medical therapies for the treatment of overactive bladder
Q35874664Cutaneous vasodilatation induced by nitric oxide‐evoked stimulation of afferent nerves in the rat
Q74623154Defects of tyrosine289phenylalanine mutation on binding and functional properties of the human tachykinin NK2 receptor stably expressed in chinese hamster ovary cells
Q42146190Demonstration of a 'septide-sensitive' inflammatory response in rat skin
Q43565356Depression of windup of spinal neurons in the neonatal rat spinal cord in vitro by an NK3 tachykinin receptor antagonist
Q43552127Design of non-peptide CCK2 and NK1 peptidomimetics using 1-(2-nitrophenyl)thiosemicarbazide as a novel common scaffold
Q42735567Design of novel neurokinin 1 receptor antagonists based on conformationally constrained aromatic amino acids and discovery of a potent chimeric opioid agonist-neurokinin 1 receptor antagonist
Q74570838Design, synthesis and biological activity of carbohydrate-containing peptidomimetics as new ligands for the human tachykinin NK-2 receptor
Q74508047Development and application of sensitive HPLC assays for NK3 antagonists in rat plasma
Q48268125Diencephalic neurons producing melanin-concentrating hormone are influenced by local and multiple extra-hypothalamic tachykininergic projections through the neurokinin 3 receptor
Q72113837Different mechanism of tachykinin NK2 receptor blockade by SR 48968 and MEN 10,627 in the guinea-pig isolated gallbladder and colon
Q43172881Differential activation of the epithelial and smooth muscle NK1 receptors by synthetic tachykinin agonists in guinea-pig trachea
Q43625228Differential alterations in tachykinin NK2 receptors in isolated colonic circular smooth muscle in inflammatory bowel disease and idiopathic chronic constipation
Q28583147Direct evidence for the interaction of neurokinin A with the tachykinin NK(1) receptor in tissue
Q74327497Distribution of Fos-like immunoreactivity within the rat brain following intraventricular injection of the selective NK(3) receptor agonist senktide
Q41836203Effect of NG-monomethyl-L-arginine on kinin-induced vasodilation in the human forearm
Q71378260Effect of SR 142801 on nitric oxide-dependent and independent responses to tachykinin NK3 receptor agonists in isolated guinea-pig colon
Q43540654Effect of a tachykinin NK(2) receptor antagonist, nepadutant, on cardiovascular and gastrointestinal function in rats and dogs
Q36922574Effect of chronic, extrinsic denervation on functional NANC innervation with vasoactive intestinal polypeptide and substance P in longitudinal muscle of rat jejunum
Q22254329Effect of nepadutant at tachykinin NK(2) receptors in human intestine and urinary bladder
Q73302803Effect of non-peptide tachykinin NK(1) receptor antagonists on non-adrenergic, non-cholinergic neurogenic mucus secretion in ferret trachea
Q74515937Effect of several bicyclic peptide and cyclic pseudopeptide tachykinin NK2 receptor antagonists in the human isolated ileum and colon
Q71771547Effect of the non-peptide blocker (+/-) CP 96,345 on the cellular mechanism involved in the response to NK1 receptor stimulation in human skin fibroblasts
Q41790903Effect of the tachykinin NK1 receptor antagonists, RP 67580 and SR 140333, on electrically-evoked substance P release from rat spinal cord
Q71549319Effect of the tachykinin receptor antagonists, SR 140333, FK 888, and SR 142801, on capsaicin-induced mouse ear oedema
Q54543921Effects of ischemia on tachykinin-containing nerves and neurokinin receptors in the rabbit bladder.
Q34079164Effects of tachykinin receptor agonists and antagonists on the guinea-pig isolated oesophagus
Q34079159Effects of tachykinins on uterine smooth muscle
Q42370128Effects of the tachykinin NK1 receptor antagonist, RP 67580, on central cardiovascular and behavioural effects of substance P, neurokinin A and neurokinin B.
Q42447559Electrophysiological evidence that neurokinin A acts via NK-1 receptors in the cat dorsal horn
Q77209775Endogenous peptidergic modulation of perisynaptic Schwann cells at the frog neuromuscular junction
Q49080608Endogenously produced substance P contributes to lymphocyte proliferation induced by dendritic cells and direct TCR ligation
Q51520191Evaluation of PD 154075, a tachykinin NK1 receptor antagonist, in a rat model of postoperative pain.
Q41979276Evidence that tachykinin NK1 and NK2 receptors mediate non-adrenergic non-cholinergic excitation and contraction in the circular muscle of guinea-pig duodenum
Q38561929Evidence that tachykinin NK2 receptors modulate resting tone in the rat isolated small intestine
Q43185063Evidence that tachykinins are the main NANC excitatory neurotransmitters in the guinea-pig common bile duct.
Q42144915Evidence that tachykinins relax the guinea-pig trachea via nitric oxide release and by stimulation of a septide-insensitive NK1 receptor
Q34397958Evolution of vertebrate neuropeptides
Q35028104Excitatory motor and electrical effects produced by tachykinins in the human and guinea-pig isolated ureter and guinea-pig renal pelvis
Q34737724Expression and coupling of neurokinin receptor subtypes to inositol phosphate and calcium signaling pathways in human airway smooth muscle cells
Q48388973Expression and presence of septal neurokinin-2 receptors controlling hippocampal acetylcholine release during sensory stimulation in rat.
Q77361337Expression of neurokinin-1 receptors on cultured dorsal root ganglion neurons from the adult rat
Q45750848Extracts and constituents of Hypericum perforatum inhibit the binding of various ligands to recombinant receptors expressed with the Semliki Forest virus system
Q41319496From acute to chronic pain: mechanisms and hypotheses.
Q48616401Functional characterization of substance P receptors on cultured human spinal cord astrocytes: synergism of substance P with cytokines in inducing interleukin-6 and prostaglandin E2 production
Q42704618Functional evidence for NO-synthase activation by substance P through a mechanism not involving classical tachykinin receptors in guinea-pig ileum in vitro.
Q24312052Functional expression of a novel human neurokinin-3 receptor homolog that binds [3H]senktide and [125I-MePhe7]neurokinin B, and is responsive to tachykinin peptide agonists
Q34793277Functional interaction between losartan and central tachykinin NK3 receptors in the conscious rat.
Q41836224Identification of both NK1 and NK2 receptors in guinea‐pig airways
Q40285095Immunolocalization of full-length NK1 tachykinin receptors in human tumors
Q32144991Immunologically induced histamine release from rat peritoneal mast cells is enhanced by low levels of substance P.
Q35027804Impaired IL-1beta-induced neutrophil accumulation in tachykinin NK1 receptor knockout mice
Q41095765Improved discriminatory properties between human and murine tachykinin NK1 receptors of MEN 10930: a new potent and competitive antagonist
Q35027801In vitro characterization of tachykinin NK2-receptors modulating motor responses of human colonic muscle strips
Q42369007Inhibition by SR 140333 of NK1 tachykinin receptor-evoked, nitric oxide-dependent vasodilatation in the hamster cheek pouch microvasculature in vivo
Q71726618Inhibition by actinomycin D of neurogenic mouse ear oedema
Q41840406Inhibition of Ca(2+)-sensitive K+ currents in NG 108-15 cells by substance P and related tachykinins
Q73024991Interleukin-1beta-induced hyperresponsiveness to [Sar9,Met(O2)11]substance P in isolated human bronchi
Q60733559Internalization of the neurokinin 1 receptor in rat myenteric neurons
Q35874499Investigation of the specificity of FK 888 as a tachykinin NK1 receptor antagonist
Q52207115Involvement of neurokinin receptors in the induction but not the maintenance of mechanical allodynia in rat flexor motoneurones.
Q37617971Involvement of substance P and the NK-1 receptor in pancreatic cancer
Q70992664Involvement of substance P as a mediator in capsaicin-induced mouse ear oedema
Q42494051Involvement of tachykinin NK2 receptors in the modulation of spontaneous motility in rat proximal colon
Q36718238Isolation and characterization of neurokinin A receptor cDNAs from guinea-pig lung and rabbit pulmonary artery
Q46433088Localisation of NK1 receptor immunoreactivity to neurons and interstitial cells of the guinea-pig gastrointestinal tract
Q36309083Localization of neurokinin B receptor in mouse gastrointestinal tract
Q80625357Long-term effects of extrinsic denervation on VIP and substance P innervation in circular muscle of rat jejunum
Q37380509Lung respiratory rhythm and pattern generation in the bullfrog: role of neurokinin-1 and mu-opioid receptors
Q28379348MEN 11420 (Nepadutant), a novel glycosylated bicyclic peptide tachykinin NK2 receptor antagonist
Q73188535Major metabolites of substance P degraded by spinal synaptic membranes antagonize the behavioral response to substance P in rats
Q40616888Membrane-induced structure of novel human tachykinin hemokinin-1 (hHK1).
Q54187439Metabolic stability of some tachykinin analogues to cell-surface peptidases: Roles for endopeptidase-24.11 and aminopeptidase N
Q71720526Modulation of gut substance P after whole-body irradiation. A new pathological feature
Q43231195Modulation on C- and N-terminal moieties of a series of potent and selective linear tachykinin NK(2) receptor antagonists
Q43260751Molecular and pharmacological characterization of a functional tachykinin NK3 receptor cloned from the rabbit iris sphincter muscle
Q32065075Molecular and pharmacological characterization of the murine tachykinin NK(3) receptor
Q73807935Molecular determinants of peptide and nonpeptide NK-2 receptor antagonists binding sites of the human tachykinin NK-2 receptor by site-directed mutagenesis
Q43254445NK-3 receptors mediate enhancement of substance P release from capsaicin-sensitive spinal cord afferent terminals
Q71652591NK1 and NK2 receptors are similar in man and rabbit
Q73413996NK1 receptor expression in the interstitial cells of Cajal and neurons and tachykinins distribution in rat ileum during development
Q71980784NK1-tachykinin receptors and prolonged, stimulus-evoked alterations in the excitability of withdrawal reflexes in the decerebrated and spinalized rabbit
Q73426217NK3 receptor blockade prevents hyperalgesia and the associated spinal cord substance P release in monoarthritic rats
Q80686325Neurogenic inflammation in lung disease: burnt out?
Q41319571Neurogenic mechanisms and neuropeptides in chronic pain
Q35042205Neurokinin B- and specific tachykinin NK(3) receptor agonists-induced airway hyperresponsiveness in the guinea-pig
Q77425680Neurokinin B- and substance P-like immunoreactivity are co-localized in enteric nerves of rat ileum
Q48451417Neurokinin receptor 3 peptide exacerbates 6-hydroxydopamine-induced dopaminergic degeneration in rats through JNK pathway.
Q33905991Neurokinin receptor antagonists
Q41143437Neurokinin receptors subserving airways secretion
Q41143430Neurokinin receptors subserving bronchoconstriction
Q48628404Neurokinin-1 and neurokinin-3 receptors are expressed in vagal efferent neurons that innervate different parts of the gastro-intestinal tract
Q43814498Neuronal bursting induced by NK3 receptor activation in the neonatal rat spinal cord in vitro
Q77748966Neuronorm is a potent and water soluble neurokinin A receptor antagonist
Q47103471Neuropeptides and ATP signaling in the trigeminal ganglion
Q34655147Neuropeptides in hyperthermia
Q46584544Nitric oxide induces acetylcholine-mediated contractions in the guinea-pig small intestine
Q35874315Non-specific actions of the non-peptide tachykinin receptor antagonists, CP-96,345, RP 67580 and SR 48968, on neurotransmission
Q40041782Novel anti-inflammatory treatments for asthma
Q41293781Novel pharmacological strategies for analgesia
Q44057884Novel potent substance P and neurokinin A receptor antagonists. Conception, synthesis and biological evaluation of indolizine derivatives
Q46799249Oxidative stress and substance P mediate psychological stress-induced autophagy and delay of hair growth in mice
Q46323752Parallel bioassay of 39 tachykinins on 11 smooth muscle preparations. Structure and receptor selectivity/affinity relationship.
Q51536511Peptidergic activation of locust dorsal unpaired median neurons: depolarization induced by locustatachykinins may be mediated by cyclic AMP.
Q51554681Peripheral effects of three novel non-peptide tachykinin NK1 receptor antagonists in the anaesthetized rat.
Q28204105Peripheral tachykinin receptors as targets for new drugs
Q36955876Peripheral tachykinins and the neurokinin receptor NK1 are required for platelet thrombus formation.
Q24673375Pharmacological profile of the novel mammalian tachykinin, hemokinin 1
Q74446250Pharmacology of the peptidomimetic, MEN 11149, a new potent, selective and orally effective tachykinin NK1 receptor antagonist
Q34060762Principles of tachykininergic co-transmission in the peripheral and enteric nervous system
Q48634338Profile of neuronal excitation following selective activation of the neurokinin-1 receptor in rat deep dorsal horn in vitro
Q44652916RNA interference prevents lipopolysaccharide-induced preprotachykinin gene expression
Q41471400Rational design of high affinity tachykinin NK1 receptor antagonists
Q36430845Relationships between neurokinin receptor-expressing interstitial cells of Cajal and tachykininergic nerves in the gut.
Q42037304Renal effects of intracerebroventricularly injected tachykinins in the conscious saline-loaded rat: receptor characterization
Q78113199Replacement of the quinoline system in 2-phenyl-4-quinolinecarboxamide NK-3 receptor antagonists
Q40085168Role of Substance P Neuropeptide in Inflammation, Wound Healing, and Tissue Homeostasis
Q28368251Role of intrathecal tachykinins for micturition in unanaesthetized rats with and without bladder outlet obstruction
Q59852872Role of neurokinin 1 receptors in dextran sulfate-induced colitis: studies with gene-deleted mice and the selective receptor antagonist netupitant
Q35041990Role of nitric oxide and septide-insensitive NK(1) receptors in bronchoconstriction induced by aerosolised neurokinin A in guinea-pigs
Q73221775Role of substance P and tachykinin receptor antagonists in citric acid-induced cough in pigs
Q33899646Role of tachykinins in asthma
Q42458136Role of tachykinins in the regulation of the hypothalamo-pituitary-adrenal axis
Q36105763Selective and combined neurokinin receptor antagonists
Q53319380Selective nasal allergen provocation induces substance P-mediated bronchial hyperresponsiveness.
Q41664954Sensory neuropeptides: their role in inflammation and wound healing
Q73404424Sequential activation of the triple excitatory transmission to the circular muscle of guinea-pig colon
Q43004987Serotonin and vasoactive intestinal peptide antagonists attenuate rotavirus diarrhoea
Q78048899Spinal actions of GR73632, a novel tachykinin NK1 receptor agonist
Q40940881Spinal cord tachykinins in the micturition reflex.
Q71657322Structural comparison of NK2 receptor agonists and antagonists
Q32148641Structure determination and by-product profile of the NK(2) receptor antagonist nepadutant, a bicyclic glycopeptide
Q36179745Structure-based design in drug discovery--the application of a peptoid drug design strategy for the development of non-peptide neuropeptide receptor ligands
Q90599304Substance P Receptor in the Rat Heart and Regulation of Its Expression in Long-Term Diabetes
Q42695078Substance P activates both contractile and inflammatory pathways in lymphatics through the neurokinin receptors NK1R and NK3R.
Q40980907Substance P activates responses correlated with tumour growth in human glioma cell lines bearing tachykinin NK1 receptors
Q41911986Substance P and Neurokinin 1 receptor - expression is affected in the ileum of mice with mutation in the W locus
Q43713612Substance P and its transglutaminase-synthesized spermine derivative elicit yawning behavior via nitric oxide in rats.
Q71911949Substance P and neurokinin A metabolism by cultured human skeletal muscle myocytes and fibroblasts
Q34075030Substance P antagonists: novel agents in the treatment of depression
Q36592563Substance P enhances the activation of AMPK and cellular lipid accumulation in 3T3‑L1 cells in response to high levels of glucose
Q46626690Substance P immunoreactive nerves and interstitial cells of Cajal in the rat and guinea-pig ileum. A histochemical and quantitative study
Q74529110Substance P receptor (neurokinin-1)-expressing neurons in lamina I of the spinal cord encode for the intensity of noxious stimulation: a c-Fos study in rat
Q30837190Substance P-evoked Cl(-) secretion in guinea pig distal colonic epithelia: interaction with PGE(2).
Q46161774Synergistic role of muscarinic acetylcholine and tachykinin NK-2 receptors in intestinal peristalsis
Q71788406Synthesis and biological evaluation of novel NK‐1 tachykinin receptor antagonists: The use of cycloalkyl amino acids as a template
Q42165713Synthesis of a novel class of non-peptide NK-2 receptor ligand, derived from 1-phenyl-3-pyrrol-1-ylindan-2-carboxamides
Q28577874Tachykinin NK(2) receptor mediates contraction and ion transport in rat colon by different mechanisms
Q51660620Tachykinin NK-1 and NK-2 receptors in the circular muscle of the guinea-pig proximal colon
Q42700984Tachykinin NK1 and NK2 receptor antagonists and atropine-resistant ascending excitatory reflex to the circular muscle of the guinea-pig ileum
Q51631464Tachykinin NK1 and NK2 receptors mediate atropine-resistant ileal circular muscle contractions evoked by capsaicin
Q24673126Tachykinin NK1 and NK2 receptors mediate inhibitory vs excitatory motor responses in human isolated corpus cavernosum and spongiosum
Q46883653Tachykinin NK1 and NK2 receptors mediate non-adrenergic non-cholinergic excitatory neuromuscular transmission in the guinea-pig stomach
Q73557239Tachykinin NK1 and NK2 receptors mediate non-adrenergic non-cholinergic excitatory neuromuscular transmission in the human ileum
Q41835345Tachykinin NK1 but not NK2 receptors mediate non-cholinergic excitatory junction potentials in the circular muscle of guinea-pig colon
Q37965737Tachykinin NK2 receptor antagonists. A patent review (2006 - 2010).
Q34400995Tachykinin NK2 receptors further characterized in the lung with nonpeptide receptor antagonists
Q52868098Tachykinin actions on deep dorsal horn neurons in vitro: an electrophysiological and morphological study in the immature rat.
Q48702539Tachykinin neurokinin-1 and neurokinin-3 receptor-mediated responses in guinea-pig substantia nigra: an in vitro electrophysiological study
Q37638682Tachykinin receptor antagonists in clinical trials
Q34147318Tachykinin receptor assays.
Q46843069Tachykinin receptors are involved in the "local efferent" motor response to capsaicin in the guinea-pig small intestine and oesophagus
Q40465220Tachykinin receptors in gastrointestinal motility
Q43169440Tachykinin receptors in the guinea-pig isolated oesophagus: a complex system
Q42875520Tachykinin-induced contraction of the guinea-pig isolated oesophageal mucosa is mediated by NK(2) receptors
Q48887663Tachykinins and central respiratory activity: an in vitro study on the newborn rat.
Q34803993Tachykinins and tachykinin receptors in bone
Q41491263Tachykinins in the gut. Part I. Expression, release and motor function
Q44537826Tachykinins mediate non-adrenergic, non-cholinergic excitatory neurotransmission to the hamster ileum via NK1 and NK2 receptors
Q41209277Tachykinins, neurotrophism and neurodegenerative diseases: a critical review on the possible role of tachykinins in the aetiology of CNS diseases
Q41093430Targeting neurokinin-3 receptor: a novel anti-angiogenesis strategy for cancer treatment
Q57110771Temporal increase in the reactivity of pulmonary vasculature to substance P in chronically hypoxic rats
Q35967286The Role of Sonic Hedgehog Signaling in Osteoclastogenesis and Jaw Bone Destruction
Q34369831The anxiolytic-like activity of GR159897, a non-peptide NK2 receptor antagonist, in rodent and primate models of anxiety
Q41633157The dual nature of the tachykinin NK1 receptor.
Q39377879The effects of NK-1 and NK-2 receptor antagonists on the capsaicin evoked synaptic response in the rat spinal cord in vitro
Q41578664The effects of tachykinins on inflammatory and immune cells
Q34975942The guinea-pig oesophagus is a versatile in vitro preparation for pharmacological studies
Q48829249The neostriatal mosaic: basis for the changing distribution of neurokinin-1 receptor immunoreactivity during development
Q73980279The neurokinin-1 receptor antagonist RP 67580 reduces the sensitization of primary afferents by substance P in the rat
Q74268477The neurokinin-2 receptor is not involved in the sensitization of primary afferents of the rat knee joint
Q74313940The nonpeptide NK-1 receptor antagonists LY303870 and LY306740 block the responses of spinal dorsal horn neurons to substance P and to peripheral noxious stimuli
Q42706973The pharmacology of GR203040, a novel, potent and selective non-peptide tachykinin NK1 receptor antagonist
Q48503485The role of lateral septal NK1 receptors in mediating anxiogenic effects induced by intracerebroventricular injection of substance P.
Q48391175The role of substance P in cerebral ischemia
Q44361751The role of the amino-terminal domain of tachykinins in neurokinin-1 receptor signaling and desensitization
Q43749930The roles of the N-terminal portions of various tachykinins in promoting salivation
Q28141864The tachykinin NK1 receptor in the brain: pharmacology and putative functions
Q71345757The tachykinin NK1 receptor mediates the migration-promoting effect of substance P on human skin fibroblasts in culture
Q29306227The tachykinin NK1 receptor. Part I: Ligands and mechanisms of cellular activation
Q41757345The tachykinin NK1 receptor. Part II: Distribution and pathophysiological roles
Q74400952Three-dimensional quantitative structure-activity relationship for several bioactive peptides searched by a convex hull-comparative molecular field analysis approach
Q60678323Topical acetyl salicylate and dipyrone attenuate neurogenic protein extravasation in rat skin in vivo
Q54074159Transglutaminase-mediated amine incorporation into substance P protects the peptide against proteolysis in vitro.
Q32061436Transglutaminase-synthesized gamma-(glutamyl5) spermidine derivative of substance P is a selective tool for neurokinin-2 receptors characterization.
Q73070134Transglutaminase-synthesized spermine derivative of substance P recognizes rat portal vein neurokinin-3 receptors
Q42701410Typical and atypical NK1 tachykinin receptor characteristics in the rabbit isolated iris sphincter
Q52507637Vascular bed-dependent roles of the peptide CGRP and nitric oxide in acid-evoked hyperaemia of the rat stomach.
Q81092905[Neurobiological mechanisms of muscle pain referral.].

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