Polyglutamine tract-binding protein-1 dysfunction induces cell death of neurons through mitochondrial stress

scientific article

Polyglutamine tract-binding protein-1 dysfunction induces cell death of neurons through mitochondrial stress is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1111/J.1471-4159.2005.03405.X
P698PubMed publication ID16104847
P5875ResearchGate publication ID7655586

P2093author name stringHitoshi Okazawa
Ichiro Kanazawa
Mei-Ling Qi
Masaya Nakagawa
Shigeki Marubuchi
Tomohiro Okuda
Yukiko Hara
Masataka Hoshino
Yo-Ichi Wada
P2860cites workAssociation of two nuclear proteins, Npw38 and NpwBP, via the interaction between the WW domain and a novel proline-rich motif containing glycine and arginineQ22010920
The Huntington's disease protein interacts with p53 and CREB-binding protein and represses transcriptionQ22254119
Bcl-xL regulates the membrane potential and volume homeostasis of mitochondriaQ24311858
The mammalian immediate-early TIS21 protein and the leukemia-associated BTG1 protein interact with a protein-arginine N-methyltransferaseQ24320461
Novel truncating mutations in the polyglutamine tract binding protein 1 gene (PQBP1) cause Renpenning syndrome and X-linked mental retardation in another family with microcephalyQ24533381
PQBP-1/Npw38, a nuclear protein binding to the polyglutamine tract, interacts with U5-15kD/dim1p via the carboxyl-terminal domainQ28139548
Evidence that dim1 associates with proteins involved in pre-mRNA splicing, and delineation of residues essential for dim1 interactions with hnRNP F and Npw38/PQBP-1Q28142421
PQBP-1, a novel polyglutamine tract-binding protein, inhibits transcription activation by Brn-2 and affects cell survivalQ28144288
Mutations in the polyglutamine binding protein 1 gene cause X-linked mental retardationQ28186625
Interaction between mutant ataxin-1 and PQBP-1 affects transcription and cell deathQ28204152
Genotype-phenotype studies in three families with mutations in the polyglutamine-binding protein 1 gene (PQBP1)Q28280938
Critical function of endogenous XIAP in regulating caspase activation during sympathetic neuronal apoptosisQ28510508
Ribin, a protein encoded by a message complementary to rRNA, modulates ribosomal transcription and cell proliferationQ28578720
Mitochondrial control of cell deathQ29617739
Molecular Pathways of Neurodegeneration in Parkinson's DiseaseQ29619903
Insoluble detergent-resistant aggregates form between pathological and nonpathological lengths of polyglutamine in mammalian cellsQ30779186
T Cell Activation-Induced Mitochondrial Hyperpolarization Is Mediated by Ca2+- and Redox-Dependent Production of Nitric OxideQ33834238
Different responses of astrocytes and neurons to nitric oxide: the role of glycolytically generated ATP in astrocyte protection.Q33953141
Apoptosis and caspases in neurodegenerative diseasesQ35097801
Antagonizing XIAP-mediated caspase-3 inhibition. Achilles' heel of cancers?Q35641603
Minocycline inhibits caspase-independent and -dependent mitochondrial cell death pathways in models of Huntington's diseaseQ35918549
Caspase inhibition extends the commitment to neuronal death beyond cytochrome c release to the point of mitochondrial depolarizationQ36342515
Biochemical and genetic analysis of the mitochondrial response of yeast to BAX and BCL-X(L)Q39452632
Mutant huntingtin directly increases susceptibility of mitochondria to the calcium-induced permeability transition and cytochrome c releaseQ40551652
Striatal cells from mutant huntingtin knock-in mice are selectively vulnerable to mitochondrial complex II inhibitor-induced cell death through a non-apoptotic pathwayQ40590116
Mitochondrial dysfunction in a cell culture model of familial amyotrophic lateral sclerosisQ40723426
Dominant-negative suppression of HNF-1 alpha results in mitochondrial dysfunction, INS-1 cell apoptosis, and increased sensitivity to ceramide-, but not to high glucose-induced cell death.Q40766274
CREB-binding protein sequestration by expanded polyglutamineQ40859094
PQBP-1 increases vulnerability to low potassium stress and represses transcription in primary cerebellar neuronsQ42522108
Partial purification and characterization of human hepatoma-derived growth factorQ42796084
Apoptosis-resistant mitochondria in T cells selected for resistance to Fas signalingQ43509302
Release of cytochrome c into the extracellular space contributes to neuronal apoptosis induced by staurosporineQ43960599
Minocycline inhibits cytochrome c release and delays progression of amyotrophic lateral sclerosis in miceQ43977943
High glucose-induced oxidative stress and mitochondrial dysfunction in neurons.Q44200273
Additive neuroprotective effects of minocycline with creatine in a mouse model of ALS.Q44296123
Mutant huntingtin promotes the fibrillogenesis of wild-type huntingtin: a potential mechanism for loss of huntingtin function in Huntington's diseaseQ44530908
AMPA-induced dark cell degeneration of cerebellar Purkinje neurons involves activation of caspases and apparent mitochondrial dysfunctionQ44671811
Mitochondrial hyperpolarization after transient oxygen-glucose deprivation and subsequent apoptosis in cultured rat hippocampal neuronsQ44672002
To learn better, keep the HAT on.Q46135047
PQBP-1 transgenic mice show a late-onset motor neuron disease-like phenotypeQ48019311
P433issue3
P407language of work or nameEnglishQ1860
P921main subjectcell deathQ2383867
P304page(s)858-70
P577publication date2005-11-01
P1433published inJournal of NeurochemistryQ6295643
P1476titlePolyglutamine tract-binding protein-1 dysfunction induces cell death of neurons through mitochondrial stress
P478volume95

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cites work (P2860)
Q38309416Hepatoma-derived growth factor, a new trophic factor for motor neurons, is up-regulated in the spinal cord of PQBP-1 transgenic mice before onset of degeneration
Q30480195New insights into mitochondrial structure during cell death
Q35854630PQBP1 Is a Proximal Sensor of the cGAS-Dependent Innate Response to HIV-1.
Q28247678The splicing factor PQBP1 regulates mesodermal and neural development through FGF signaling
Q47070332X chromosome-linked intellectual disability protein PQBP1 associates with and regulates the translation of specific mRNAs

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