| scholarly article | Q13442814 |
| P50 | author | Filippo Caraci | Q83164166 |
| Georg C Terstappen | Q130272397 | ||
| Andrea Caricasole | Q130272400 | ||
| Ferdinando Nicoletti | Q56541999 | ||
| P2093 | author name string | Agata Copani | |
| Alessandra Caruso | |||
| Annemieke J Rozemuller | |||
| Eleonora Aronica | |||
| Giovanni Gaviraghi | |||
| Marianna Storto | |||
| P2860 | cites work | Lithium induces gene expression through lymphoid enhancer-binding factor/T-cell factor responsive element in rat PC12 cells | Q77371368 |
| Signal transduction by the Wnt family of ligands | Q24530639 | ||
| The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics | Q27860914 | ||
| Human Dkk-1, a gene encoding a Wnt antagonist, responds to DNA damage and its overexpression sensitizes brain tumor cells to apoptosis following alkylation damage of DNA | Q28200753 | ||
| Wnt signalling: antagonistic Dickkopfs | Q28214105 | ||
| Activation of Wnt signaling rescues neurodegeneration and behavioral impairments induced by beta-amyloid fibrils | Q28570115 | ||
| The multifaceted roles of glycogen synthase kinase 3beta in cellular signaling | Q29620489 | ||
| Regulation of p53 in response to DNA damage | Q33807801 | ||
| The role of apolipoprotein E in Alzheimer's disease: pharmacogenomic target selection | Q33971309 | ||
| Molecular cloning and initial characterization of the MG61/PORC gene, the human homologue of the Drosophila segment polarity gene Porcupine | Q34130592 | ||
| p53-dependent apoptosis pathways. | Q34305233 | ||
| Wnt signaling involvement in beta-amyloid-dependent neurodegeneration. | Q34784360 | ||
| The Wnt pathway, cell-cycle activation and beta-amyloid: novel therapeutic strategies in Alzheimer's disease? | Q35136322 | ||
| Causative and susceptibility genes for Alzheimer's disease: a review. | Q35146030 | ||
| Wnt-1 modulates cell-cell adhesion in mammalian cells by stabilizing beta-catenin binding to the cell adhesion protein cadherin | Q36233814 | ||
| Selective cytotoxicity of intracellular amyloid beta peptide1-42 through p53 and Bax in cultured primary human neurons | Q36324215 | ||
| Apoptosis is induced by beta-amyloid in cultured central nervous system neurons | Q36501389 | ||
| Staging of Alzheimer's disease-related neurofibrillary changes | Q40416705 | ||
| A potential role for apoptosis in neurodegeneration and Alzheimer's disease | Q40437117 | ||
| Akt participation in the Wnt signaling pathway through Dishevelled | Q40817549 | ||
| Beta-catenin: a key mediator of Wnt signaling | Q41732761 | ||
| Erratic expression of DNA polymerases by beta-amyloid causes neuronal death. | Q44192054 | ||
| Protein kinase C inhibits amyloid beta peptide neurotoxicity by acting on members of the Wnt pathway. | Q44192070 | ||
| Abnormalities of Wnt signalling in schizophrenia--evidence for neurodevelopmental abnormality | Q47959350 | ||
| Activation of tau protein kinase I/glycogen synthase kinase-3beta by amyloid beta peptide (25-35) enhances phosphorylation of tau in hippocampal neurons | Q48354068 | ||
| AbetaPP induces cdk5-dependent tau hyperphosphorylation in transgenic mice Tg2576. | Q48439872 | ||
| Evidence supporting WNT2 as an autism susceptibility gene. | Q48810402 | ||
| Expression of TGF-beta s and their receptors during implantation and organogenesis of the mouse embryo. | Q52212762 | ||
| Evidence for apoptotic cell death in Alzheimer's disease. | Q53200058 | ||
| Microglia, amyloid and dementia in alzheimer disease. A correlative study. | Q53234672 | ||
| Dickkopf-1, an inhibitor of the Wnt signaling pathway, is induced by p53. | Q55475779 | ||
| Phosphorylation of tau protein by recombinant GSK-3beta: pronounced phosphorylation at select Ser/Thr-Pro motifs but no phosphorylation at Ser262 in the repeat domain | Q60603639 | ||
| Involvement of glyceraldehyde-3-phosphate dehydrogenase (GAPDH) and p53 in neuronal apoptosis: evidence that GAPDH is upregulated by p53 | Q73107353 | ||
| Mitotic signaling by beta-amyloid causes neuronal death | Q73263325 | ||
| Wnt signaling function in Alzheimer's disease | Q74248964 | ||
| P433 | issue | 26 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | Alzheimer's disease | Q11081 |
| brain | Q1073 | ||
| P304 | page(s) | 6021-6027 | |
| P577 | publication date | 2004-06-30 | |
| P1433 | published in | Journal of Neuroscience | Q1709864 |
| P1476 | title | Induction of Dickkopf-1, a negative modulator of the Wnt pathway, is associated with neuronal degeneration in Alzheimer's brain | |
| P478 | volume | 24 |
| Q33606991 | A common biological mechanism in cancer and Alzheimer's disease? |
| Q93373716 | A novel high-content imaging-based technique for measuring binding of Dickkopf-1 to low-density lipoprotein receptor-related protein 6 |
| Q58714162 | A role for APP in Wnt signalling links synapse loss with β-amyloid production |
| Q41438444 | Aberrant Wnt signaling pathway in medial temporal lobe structures of Alzheimer's disease |
| Q39387696 | Aberrant Wnt signaling: a special focus in CNS diseases |
| Q35034360 | Activation of Wnt/β-catenin signaling in Muller glia protects photoreceptors in a mouse model of inherited retinal degeneration |
| Q46254513 | Activity-dependent synaptic Wnt release regulates hippocampal long term potentiation |
| Q28075617 | Alzheimer Disease: Crosstalk between the Canonical Wnt/Beta-Catenin Pathway and PPARs Alpha and Gamma |
| Q96348254 | Amyloid β neurotoxicity is IDO1-Kyn-AhR dependent and blocked by IDO1 inhibitor |
| Q47620637 | Amyloid β synaptotoxicity is Wnt-PCP dependent and blocked by fasudil. |
| Q29977753 | Amyloid-beta binds to the extracellular cysteine-rich domain of Frizzled and inhibits Wnt/beta-catenin signaling |
| Q37361564 | Amyloid-β oligomers regulate the properties of human neural stem cells through GSK-3β signaling |
| Q37409308 | Association between osteocalcin and cognitive performance in healthy older adults. |
| Q94594156 | Associations of Bone Turnover Markers with Cognitive Function in Patients Undergoing Hemodialysis |
| Q100504005 | Caffeine inhibits Notum activity by binding at the catalytic pocket |
| Q39807502 | Calcium/calmodulin-dependent protein kinase type IV is a target gene of the Wnt/beta-catenin signaling pathway. |
| Q36580159 | Characterization of Wnt signaling during photoreceptor degeneration |
| Q41849989 | Chronic hypoxia induces the activation of the Wnt/β-catenin signaling pathway and stimulates hippocampal neurogenesis in wild-type and APPswe-PS1ΔE9 transgenic mice in vivo. |
| Q57050335 | Chronic noise exposure exacerbates AD-like neuropathology in SAMP8 mice in relation to Wnt signaling in the PFC and hippocampus |
| Q64087689 | Clusterin in Alzheimer's Disease: Mechanisms, Genetics, and Lessons From Other Pathologies |
| Q29870999 | Clusterin regulates β-amyloid toxicity via Dickkopf-1-driven induction of the wnt-PCP-JNK pathway |
| Q35839636 | Common genetic variation within the low-density lipoprotein receptor-related protein 6 and late-onset Alzheimer's disease |
| Q38645158 | Comparing the Effects of Melatonin with Caloric Restriction in the Hippocampus of Aging Mice: Involvement of Sirtuin1 and the FOXOs Pathway |
| Q35768464 | DKK1 is a potential novel mediator of cisplatin-refractoriness in non-small cell lung cancer cell lines |
| Q34350189 | Deficiency in LRP6-mediated Wnt signaling contributes to synaptic abnormalities and amyloid pathology in Alzheimer's disease. |
| Q58698087 | Deficient Wnt Signaling and Synaptic Vulnerability in Alzheimer’s Disease: Emerging Roles for the LRP6 Receptor |
| Q28591970 | Deficient Wnt signalling triggers striatal synaptic degeneration and impaired motor behaviour in adult mice |
| Q42725479 | Dickkopf 1 mediates glucocorticoid-induced changes in human neural progenitor cell proliferation and differentiation |
| Q58750104 | Dickkopf-3 Causes Neuroprotection by Inducing Vascular Endothelial Growth Factor |
| Q48105192 | Dickkopf-related protein 3 is a potential Aβ-associated protein in Alzheimer's Disease |
| Q33646702 | Differential Modulation of TCF/LEF-1 Activity by the Soluble LRP6-ICD |
| Q46910883 | Differential activation of the calcium/protein kinase C and the canonical beta-catenin pathway by Wnt1 and Wnt7a produces opposite effects on cell proliferation in PC12 cells |
| Q28508090 | Dkk1 regulates ventral midbrain dopaminergic differentiation and morphogenesis |
| Q64057521 | Downregulated Wnt/β-catenin signalling in the Down syndrome hippocampus |
| Q29347521 | Dysfunction of Wnt signaling and synaptic disassembly in neurodegenerative diseases |
| Q46293996 | Effects of cannabidiol interactions with Wnt/β-catenin pathway and PPARγ on oxidative stress and neuroinflammation in Alzheimer's disease |
| Q46691801 | Enhanced tau phosphorylation in the hippocampus of mice treated with 3,4-methylenedioxymethamphetamine ("Ecstasy"). |
| Q37241063 | Estrogen regulation of Dkk1 and Wnt/β-Catenin signaling in neurodegenerative disease |
| Q47624153 | Evaluation of Synapse Density in Hippocampal Rodent Brain Slices. |
| Q94544608 | Exercise Attenuates Brain Aging by Rescuing Down-Regulated Wnt/β-Catenin Signaling in Aged Rats |
| Q51061345 | Fluoride Induces Neuroinflammation and Alters Wnt Signaling Pathway in BV2 Microglial Cells. |
| Q37364186 | Fluoxetine Prevents Aβ1-42-Induced Toxicity via a Paracrine Signaling Mediated by Transforming-Growth-Factor-β1. |
| Q36672665 | Function and biological roles of the Dickkopf family of Wnt modulators |
| Q37005265 | Functional Characterization of a Small-Molecule Inhibitor of the DKK1-LRP6 Interaction |
| Q36787346 | Functional genomic analyses identify pathways dysregulated by progranulin deficiency, implicating Wnt signaling |
| Q42748129 | GSK3 Function in the Brain during Development, Neuronal Plasticity, and Neurodegeneration |
| Q38365364 | Hippocampal Wnt Signaling: Memory Regulation and Hormone Interactions. |
| Q34797526 | Huperzine A activates Wnt/β-catenin signaling and enhances the nonamyloidogenic pathway in an Alzheimer transgenic mouse model |
| Q34063312 | Huperzine A: Is it an Effective Disease-Modifying Drug for Alzheimer's Disease? |
| Q54978082 | Impaired Wnt Signaling in the Prefrontal Cortex of Alzheimer's Disease. |
| Q49417153 | Impaired Wnt signaling in dopamine containing neurons is associated with pathogenesis in a rotenone triggered Drosophila Parkinson's disease model |
| Q50861765 | In vivo activation of Wnt signaling pathway enhances cognitive function of adult mice and reverses cognitive deficits in an Alzheimer's disease model. |
| Q37261432 | Inclusion body myositis: a view from the Caenorhabditis elegans muscle |
| Q48651285 | Increased Dickkopf-1 expression is correlated with poisoning severity in carbon monoxide-poisoned humans and rats |
| Q48974850 | Induction of Dickkopf-1, a negative modulator of the Wnt pathway, is required for the development of ischemic neuronal death. |
| Q33815184 | Induction of the Wnt antagonist Dickkopf-1 is involved in stress-induced hippocampal damage. |
| Q48900276 | Induction of the Wnt antagonist, Dickkopf-1, contributes to the development of neuronal death in models of brain focal ischemia. |
| Q48201269 | Induction of the Wnt inhibitor, Dickkopf-1, is associated with neurodegeneration related to temporal lobe epilepsy |
| Q46608687 | Inhibition of Wnt and PI3K signaling modulates GSK-3beta activity and induces morphological changes in cortical neurons: role of tau phosphorylation. |
| Q48460242 | Inhibition of Wnt signaling induces amyloidogenic processing of amyloid precursor protein and the production and aggregation of Amyloid-β (Aβ)42 peptides |
| Q24296942 | Inhibition of the canonical Wnt pathway by Dickkopf-1 contributes to the neurodegeneration in 6-OHDA-lesioned rats |
| Q28771380 | Inhibition of the canonical Wnt signaling pathway by apolipoprotein E4 in PC12 cells |
| Q27301311 | Is L-methionine a trigger factor for Alzheimer's-like neurodegeneration?: Changes in Aβ oligomers, tau phosphorylation, synaptic proteins, Wnt signaling and behavioral impairment in wild-type mice |
| Q58721505 | Lithium as a disease-modifying agent for prion diseases |
| Q36672688 | Long-term estrogen deprivation leads to elevation of Dickkopf-1 and dysregulation of Wnt/β-Catenin signaling in hippocampal CA1 neurons |
| Q33667195 | Melatonin regulates the aging mouse hippocampal homeostasis via the sirtuin1-FOXO1 pathway |
| Q35197096 | Molecular actions and therapeutic potential of lithium in preclinical and clinical studies of CNS disorders |
| Q92649463 | Multi-Loop Model of Alzheimer Disease: An Integrated Perspective on the Wnt/GSK3β, α-Synuclein, and Type 3 Diabetes Hypotheses |
| Q35144310 | N-butylidenephthalide attenuates Alzheimer's disease-like cytopathy in Down syndrome induced pluripotent stem cell-derived neurons |
| Q37584417 | Neurogenesis and Alzheimer's disease: at the crossroads |
| Q46833725 | Neuroprotective Role of Novel Triazine Derivatives by Activating Wnt/β Catenin Signaling Pathway in Rodent Models of Alzheimer's Disease |
| Q37549551 | Neurosteroids Involvement in the Epigenetic Control of Memory Formation and Storage |
| Q90630267 | New insights into Wnt signaling alterations in amyotrophic lateral sclerosis: a potential therapeutic target? |
| Q38149943 | New insights into the role of glycogen synthase kinase-3 in Alzheimer's disease. |
| Q26866006 | New pharmacological strategies for treatment of Alzheimer's disease: focus on disease modifying drugs |
| Q47557165 | Olfactory memory is enhanced in mice exposed to extremely low-frequency electromagnetic fields via Wnt/β-catenin dependent modulation of subventricular zone neurogenesis |
| Q34544243 | Oligomeric Aβ-induced synaptic dysfunction in Alzheimer's disease |
| Q42580206 | Palmitoylethanolamide controls reactive gliosis and exerts neuroprotective functions in a rat model of Alzheimer's disease |
| Q64064683 | Parallel profiling of DNA methylation and hydroxymethylation highlights neuropathology-associated epigenetic variation in Alzheimer's disease |
| Q33794494 | Pentazocine Protects SN4741 Cells Against MPP+-Induced Cell Damage via Up-Regulation of the Canonical Wnt/β-Catenin Signaling Pathway |
| Q42722184 | Phosphorylation of PPP(S/T)P motif of the free LRP6 intracellular domain is not required to activate the Wnt/beta-catenin pathway and attenuate GSK3beta activity |
| Q38867198 | Plasma dickkopf-related protein 1, an antagonist of the Wnt pathway, is associated with HIV-associated neurocognitive impairment |
| Q50437287 | Prenatal high sucrose intake affected learning and memory of aged rat offspring with abnormal oxidative stress and NMDARs/Wnt signaling in the hippocampus |
| Q92402674 | Presymptomatic Treatment With Andrographolide Improves Brain Metabolic Markers and Cognitive Behavior in a Model of Early-Onset Alzheimer's Disease |
| Q40365406 | Remarkable impairment of Wnt/β-catenin signaling in the brains of the mice infected with scrapie agents |
| Q91695227 | Restoring Wnt/β-catenin signaling is a promising therapeutic strategy for Alzheimer's disease |
| Q41507015 | Reversal of Synapse Degeneration by Restoring Wnt Signaling in the Adult Hippocampus |
| Q89608062 | Riluzole: a therapeutic strategy in Alzheimer's disease by targeting the WNT/β-catenin pathway |
| Q37091609 | Role of Dickkopf-1, an antagonist of the Wnt/beta-catenin signaling pathway, in estrogen-induced neuroprotection and attenuation of tau phosphorylation |
| Q36798886 | Role of the Transforming-Growth-Factor-β1 Gene in Late-Onset Alzheimer's Disease: Implications for the Treatment |
| Q38176898 | Role of wnt signaling in the control of adult hippocampal functioning in health and disease: therapeutic implications. |
| Q41863070 | S100B induces tau protein hyperphosphorylation via Dickopff-1 up-regulation and disrupts the Wnt pathway in human neural stem cells. |
| Q36626700 | Secreted and transmembrane wnt inhibitors and activators |
| Q38200151 | Signaling pathway cross talk in Alzheimer's disease |
| Q49017578 | Stress-induced upregulation of VLDL receptor alters Wnt-signaling in neurons. |
| Q38077507 | Systemic effects of Wnt signaling |
| Q37635281 | TGF-β1 pathway as a new target for neuroprotection in Alzheimer's disease |
| Q36961595 | Target deconvolution strategies in drug discovery |
| Q36506697 | Targeting Wnt pathways in disease |
| Q35594575 | Tau reduction prevents Aβ-induced axonal transport deficits by blocking activation of GSK3β. |
| Q37035378 | The GSK3 hypothesis of Alzheimer's disease |
| Q49804881 | The Role of Wnt Signal in Glioblastoma Development and Progression: A Possible New Pharmacological Target for the Therapy of This Tumor |
| Q37144218 | The Wnt antagonist, Dickkopf-1, as a target for the treatment of neurodegenerative disorders. |
| Q40025151 | The Wnt pool of glycogen synthase kinase 3beta is critical for trophic-deprivation-induced neuronal death |
| Q47555859 | The Wnt signaling pathway is differentially expressed during the bovine herpesvirus 1 latency-reactivation cycle: evidence that two protein kinases associated with neuronal survival (Akt3 and bone morphogenetic protein receptor 2) are expressed at h |
| Q39000464 | The age factor in axonal repair after spinal cord injury: A focus on neuron-intrinsic mechanisms |
| Q28115237 | The importance of Wnt signalling for neurodegeneration in Parkinson's disease |
| Q24299312 | The low density lipoprotein receptor-related protein 6 interacts with glycogen synthase kinase 3 and attenuates activity |
| Q35828711 | The oxidative stress response regulates DKK1 expression through the JNK signaling cascade in multiple myeloma plasma cells |
| Q26991986 | The regulation and deregulation of Wnt signaling by PARK genes in health and disease |
| Q39741741 | The regulation of Dkk1 expression during embryonic development. |
| Q42390629 | The role of Wnt signaling in neuronal dysfunction in Alzheimer's Disease |
| Q33634629 | The role of Wnt signaling in the development of Alzheimer's disease: a potential therapeutic target? |
| Q48624099 | The secreted Wnt antagonist Dickkopf-1 is required for amyloid β-mediated synaptic loss. |
| Q28277009 | The ups and downs of Wnt signaling in prevalent neurological disorders |
| Q24626017 | Therapeutic potential of mood stabilizers lithium and valproic acid: beyond bipolar disorder |
| Q30494084 | Uncovering molecular biomarkers that correlate cognitive decline with the changes of hippocampus' gene expression profiles in Alzheimer's disease |
| Q38101982 | Understanding the relationship between GSK-3 and Alzheimer's disease: a focus on how GSK-3 can modulate synaptic plasticity processes |
| Q92422653 | WNT Signaling in Disease |
| Q34722036 | WNT signaling in activated microglia is proinflammatory. |
| Q38121069 | WNT signaling in neuronal maturation and synaptogenesis |
| Q36793426 | WNT signaling underlies the pathogenesis of neuropathic pain in rodents |
| Q33999052 | WNT5A signaling contributes to Aβ-induced neuroinflammation and neurotoxicity |
| Q35093167 | WNTS and WNT receptors as therapeutic tools and targets in human disease processes. |
| Q92698961 | Wnt Signaling Deregulation in the Aging and Alzheimer's Brain |
| Q98771738 | Wnt Signaling Pathway Dysregulation in the Aging Brain: Lessons From the Octodon degus |
| Q36086193 | Wnt and extraocular muscle sparing in amyotrophic lateral sclerosis |
| Q38113139 | Wnt and lithium: a common destiny in the therapy of nervous system pathologies? |
| Q35788801 | Wnt pathway in atypical teratoid rhabdoid tumors |
| Q59796856 | Wnt proteins as modulators of synaptic plasticity |
| Q34658275 | Wnt signaling and the control of human stem cell fate. |
| Q35251157 | Wnt signaling in amygdala-dependent learning and memory |
| Q27008843 | Wnt signaling in neuropsychiatric disorders: ties with adult hippocampal neurogenesis and behavior |
| Q38189240 | Wnt signaling in the nervous system and in Alzheimer's disease. |
| Q27000787 | Wnt signaling in the vertebrate central nervous system: from axon guidance to synaptic function |
| Q38060562 | Wnt signaling: role in Alzheimer disease and schizophrenia |
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| Q37032393 | Wnt-pathway activation during the early stage of neurodegeneration in FTDP-17 mice |
| Q52593421 | Wnt3a ligand facilitates autophagy in hippocampal neurons by modulating a novel GSK-3β-AMPK axis. |
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| Q38172119 | Wnts in adult brain: from synaptic plasticity to cognitive deficiencies |
| Q53397123 | miRNA-431 Prevents Amyloid-β-Induced Synapse Loss in Neuronal Cell Culture Model of Alzheimer's Disease by Silencing Kremen1. |
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