SALL4 is a key transcription regulator in normal human hematopoiesis

scientific article

SALL4 is a key transcription regulator in normal human hematopoiesis is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1111/J.1537-2995.2012.03888.X
P3181OpenCitations bibliographic resource ID609220
P932PMC publication ID3653586
P698PubMed publication ID22934838
P5875ResearchGate publication ID230767642

P2093author name stringYupo Ma
Jianchang Yang
Li Chai
Daniel G Tenen
Jie He
Ailing Li
Chong Gao
Grace S Kao
Hiro Tatetu
Nikki R Kong
Shikiko Ueno
Youyang Yang
P2860cites workSall4 regulates distinct transcription circuitries in different blastocyst-derived stem cell lineages.Q39937872
Head and tail development of the Drosophila embryo involves spalt, a novel homeotic gene.Q41090703
CD34+ marrow cells, devoid of T and B lymphocytes, reconstitute stable lymphopoiesis and myelopoiesis in lethally irradiated allogeneic baboonsQ41094042
Dissecting the role of SALL4, a newly identified stem cell factor, in chronic myelogenous leukemiaQ42143823
Loss of function of the homeobox gene Hoxa-9 perturbs early T-cell development and induces apoptosis in primitive thymocytes.Q43419606
PTEN maintains haematopoietic stem cells and acts in lineage choice and leukaemia preventionQ59067116
Biology of CD34+CD38- cells in lymphohematopoiesisQ77737226
Enhanced self-renewal of hematopoietic stem cells mediated by the polycomb gene product Bmi-1Q81119990
Duane radial ray syndrome (Okihiro syndrome) maps to 20q13 and results from mutations in SALL4, a new member of the SAL familyQ24632196
Bmi-1 is a target gene for SALL4 in hematopoietic and leukemic cellsQ24669757
Loss of expression of the Hoxa-9 homeobox gene impairs the proliferation and repopulating ability of hematopoietic stem cellsQ24670084
Novel mutations in the gene SALL4 provide further evidence for acro-renal-ocular and Okihiro syndromes being allelic entities, and extend the phenotypic spectrumQ24675032
Mutations at the SALL4 locus on chromosome 20 result in a range of clinically overlapping phenotypes, including Okihiro syndrome, Holt-Oram syndrome, acro-renal-ocular syndrome, and patients previously reported to represent thalidomide embryopathyQ24676719
SALL4, a novel oncogene, is constitutively expressed in human acute myeloid leukemia (AML) and induces AML in transgenic miceQ24685799
spalt encodes an evolutionarily conserved zinc finger protein of novel structure which provides homeotic gene function in the head and tail region of the Drosophila embryoQ26782010
Expression of HOX genes, HOX cofactors, and MLL in phenotypically and functionally defined subpopulations of leukemic and normal human hematopoietic cellsQ28137796
Bmi-1 is required for maintenance of adult self-renewing haematopoietic stem cellsQ28201183
Okihiro syndrome is caused by SALL4 mutationsQ28209941
Stem cell factor SALL4 represses the transcriptions of PTEN and SALL1 through an epigenetic repressor complexQ28244856
The murine homolog of SALL4, a causative gene in Okihiro syndrome, is essential for embryonic stem cell proliferation, and cooperates with Sall1 in anorectal, heart, brain and kidney developmentQ28247514
Sall4 interacts with Nanog and co-occupies Nanog genomic sites in embryonic stem cellsQ28251945
Sall4 modulates embryonic stem cell pluripotency and early embryonic development by the transcriptional regulation of Pou5f1Q28264106
Murine inner cell mass-derived lineages depend on Sall4 functionQ28270152
SALL4 is a key regulator of survival and apoptosis in human leukemic cellsQ28280516
A Sall4 mutant mouse model useful for studying the role of Sall4 in early embryonic development and organogenesisQ28282843
IVIC syndrome is caused by a c.2607delA mutation in the SALL4 locusQ28285272
Mice bearing a targeted interruption of the homeobox gene HOXA9 have defects in myeloid, erythroid, and lymphoid hematopoiesis.Q34418792
SALL4 is a robust stimulator for the expansion of hematopoietic stem cellsQ35125909
Enhanced self-renewal of hematopoietic stem/progenitor cells mediated by the stem cell gene Sall4Q35252403
Antigen CD34+ marrow cells engraft lethally irradiated baboonsQ35587124
Genome-wide analysis reveals Sall4 to be a major regulator of pluripotency in murine-embryonic stem cellsQ37018962
HOXA9 is required for survival in human MLL-rearranged acute leukemiasQ37129652
P4510describes a project that usesCytoscapeQ3699942
P433issue5
P407language of work or nameEnglishQ1860
P921main subjecthemopoiesisQ919283
P304page(s)1037-49
P577publication date2013-05-01
P1433published inTransfusionQ15758500
P1476titleSALL4 is a key transcription regulator in normal human hematopoiesis
P478volume53

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cites work (P2860)
Q38628583A New Indole Derivative Decreased SALL4 Gene Expression in Acute Promyelocytic Leukemia Cell Line (NB4)
Q28298834A SALL4/MLL/HOXA9 pathway in murine and human myeloid leukemogenesis
Q28597089Ex-vivo expansion of nonhuman primate CD34(+) cells by stem cell factor Sall4B
Q38805786Functional and clinical significance of SALL4 in breast cancer.
Q92645575High expression of SALL4 is associated with poor prognosis in squamous cell carcinoma of the uterine cervix
Q28300940Histone lysine-specific demethylase 1 (LSD1) protein is involved in Sal-like protein 4 (SALL4)-mediated transcriptional repression in hematopoietic stem cells
Q37024249Inhibition of SALL4 reduces tumorigenicity involving epithelial-mesenchymal transition via Wnt/β-catenin pathway in esophageal squamous cell carcinoma
Q37389409Leukemic survival factor SALL4 contributes to defective DNA damage repair
Q33618541Oncofetal gene SALL4 and prognosis in cancer: A systematic review with meta-analysis.
Q47747424SALL4 as a transcriptional and epigenetic regulator in normal and leukemic hematopoiesis
Q52597548SALL4 oncogene is an immunogenic antigen presented in various HLA-DR contexts.
Q45903019SALL4 suppresses PTEN expression to promote glioma cell proliferation via PI3K/AKT signaling pathway.
Q28273464SALL4, the missing link between stem cells, development and cancer
Q34718209Sall4 overexpression blocks murine hematopoiesis in a dose-dependent manner
Q28302909Stem cell factor SALL4, a potential prognostic marker for myelodysplastic syndromes
Q42122424Stem cell gene SALL4 in aggressive hepatocellular carcinoma: a cancer stem cell-specific target?
Q89767252Thalidomide Inhibits Human iPSC Mesendoderm Differentiation by Modulating CRBN-dependent Degradation of SALL4
Q36998221The characteristic expression pattern of BMI-1 and SALL4 genes in placenta tissue and cord blood
Q40560744The next new target in leukemia: The embryonic stem cell gene SALL4.
Q42281102The stem cell factor SALL4 is an essential transcriptional regulator in mixed lineage leukemia-rearranged leukemogenesis
Q34655962Very small embryonic-like stem cells (VSELs) represent a real challenge in stem cell biology: recent pros and cons in the midst of a lively debate.

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