Stereoselective analysis of hydroxybupropion and application to drug interaction studies

scientific article

Stereoselective analysis of hydroxybupropion and application to drug interaction studies is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1002/CHIR.20356
P698PubMed publication ID17167747

P2093author name stringAndrew J McLachlan
Annette S Gross
Hongmei Xu
Katarzyna K Loboz
P2860cites workBehavioral and biochemical investigations of bupropion metabolitesQ28156301
Pharmacokinetic optimisation of sustained-release bupropion for smoking cessationQ34137853
Effects of prototypical microsomal enzyme inducers on cytochrome P450 expression in cultured human hepatocytesQ34184221
Comparative pharmacokinetics and pharmacodynamics of the rifamycin antibacterialsQ34296734
Enantioselective effects of hydroxy metabolites of bupropion on behavior and on function of monoamine transporters and nicotinic receptorsQ34342464
Synthesis and evaluation of the antidepressant activity of the enantiomers of bupropionQ34344602
Pharmacological significance of the species differences in bupropion metabolismQ34685532
Bupropion: pharmacological and clinical profile in smoking cessation.Q35073939
Enantiomeric determination of the phenylmorpholinol metabolite of bupropion in human plasma using coupled achiral-chiral liquid chromatographyQ36866718
Regulation of CYP2B6 in primary human hepatocytes by prototypical inducersQ40587140
Single-dose pharmacokinetics of bupropion in adolescents: effects of smoking status and genderQ43673470
Induction of cytochrome P450 enzymes in cultured precision-cut human liver slicesQ44313267
HPLC assay for bupropion and its major metabolites in human plasmaQ46596611
Pharmacokinetics of bupropion and its metabolites in cigarette smokers versus nonsmokers.Q50922300
Pharmacokinetics of bupropion and its major basic metabolites in normal subjects after a single doseQ69968314
Pharmacokinetics of single- and multiple-dose bupropion in elderly patients with depressionQ71483223
P433issue3
P407language of work or nameEnglishQ1860
P921main subjectstereoselectivityQ903429
P304page(s)163-70
P577publication date2007-03-01
P1433published inChiralityQ2120255
P1476titleStereoselective analysis of hydroxybupropion and application to drug interaction studies
P478volume19

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cites work (P2860)
Q37810213Chiral Determination of Antidepressant Drugs and their Metabolites in Biological Samples
Q42407006Chiral Plasma Pharmacokinetics and Urinary Excretion of Bupropion and Metabolites in Healthy Volunteers
Q48027985Chirality and neuropsychiatric drugs: an update on stereoselective disposition and clinical pharmacokinetics of bupropion
Q88658051Common Polymorphisms of CYP2B6 Influence Stereoselective Bupropion Disposition
Q36796793Development and validation of a high-throughput stereoselective LC-MS/MS assay for bupropion, hydroxybupropion, erythrohydrobupropion, and threohydrobupropion in human plasma
Q37148882Influence of CYP2B6 genetic variants on plasma and urine concentrations of bupropion and metabolites at steady state.
Q37358704Inhibition of Cytochrome P450 2B6 Activity by Voriconazole Profiled Using Efavirenz Disposition in Healthy Volunteers
Q37153012Rifampin enhances cytochrome P450 (CYP) 2B6-mediated efavirenz 8-hydroxylation in healthy volunteers
Q33927695Sensitive, selective and rapid determination of bupropion and its major active metabolite, hydroxybupropion, in human plasma by LC-MS/MS: application to a bioequivalence study in healthy Indian subjects
Q36236685Simultaneous quantitative determination of bupropion and its three major metabolites in human umbilical cord plasma and placental tissue using high-performance liquid chromatography-tandem mass spectrometry
Q35376254Stereo-specific LC and LC-MS bioassays of antidepressants and psychotics
Q36737009Stereoselective Glucuronidation of Bupropion Metabolites In Vitro and In Vivo
Q41153557Stereoselective metabolism of bupropion by cytochrome P4502B6 (CYP2B6) and human liver microsomes
Q36900154Stereoselective method to quantify bupropion and its three major metabolites, hydroxybupropion, erythro-dihydrobupropion, and threo-dihydrobupropion using HPLC-MS/MS
Q51831896Synthesis of deuterium-labeled hydroxybupropion.
Q36733922Use of enantiomeric bupropion and hydroxybupropion to assess CYP2B6 activity in glomerular kidney diseases

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